CN1634007A - 快速杀灭多种性病病原体的苯扎氯胺避孕凝胶 - Google Patents
快速杀灭多种性病病原体的苯扎氯胺避孕凝胶 Download PDFInfo
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- CN1634007A CN1634007A CN 200410088709 CN200410088709A CN1634007A CN 1634007 A CN1634007 A CN 1634007A CN 200410088709 CN200410088709 CN 200410088709 CN 200410088709 A CN200410088709 A CN 200410088709A CN 1634007 A CN1634007 A CN 1634007A
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- eradication
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- venereal disease
- benzalkonii chloridum
- benzalkonium chloride
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- 201000010099 disease Diseases 0.000 title claims abstract description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 13
- 244000052769 pathogen Species 0.000 title claims abstract description 11
- 229960000686 benzalkonium chloride Drugs 0.000 title abstract 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003433 contraceptive agent Substances 0.000 title abstract 2
- 230000002254 contraceptive effect Effects 0.000 title abstract 2
- 230000008029 eradication Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000008367 deionised water Substances 0.000 claims abstract description 6
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 6
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 6
- XIWFQDBQMCDYJT-UHFFFAOYSA-M benzyl-dimethyl-tridecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 XIWFQDBQMCDYJT-UHFFFAOYSA-M 0.000 claims description 19
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 10
- 230000001717 pathogenic effect Effects 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 5
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 5
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 5
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 5
- 150000004702 methyl esters Chemical class 0.000 claims description 5
- 241001116389 Aloe Species 0.000 claims description 2
- 235000011399 aloe vera Nutrition 0.000 claims description 2
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims description 2
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 abstract description 2
- JBIROUFYLSSYDX-UHFFFAOYSA-M benzododecinium chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 JBIROUFYLSSYDX-UHFFFAOYSA-M 0.000 abstract 1
- XCRBXWCUXJNEFX-UHFFFAOYSA-N peroxybenzoic acid Chemical compound OOC(=O)C1=CC=CC=C1 XCRBXWCUXJNEFX-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 208000019802 Sexually transmitted disease Diseases 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 238000007865 diluting Methods 0.000 description 3
- 208000030507 AIDS Diseases 0.000 description 2
- 241000204031 Mycoplasma Species 0.000 description 1
- 241000588653 Neisseria Species 0.000 description 1
- 241000589884 Treponema pallidum Species 0.000 description 1
- 241000202921 Ureaplasma urealyticum Species 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- 229960001716 benzalkonium Drugs 0.000 description 1
- CYDRXTMLKJDRQH-UHFFFAOYSA-N benzododecinium Chemical compound CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 CYDRXTMLKJDRQH-UHFFFAOYSA-N 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
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Abstract
本发明提供了一种快速杀灭多种性病病原体的苯扎氯胺避孕凝胶。其特征在于：其中含有按重量百分比计的如下成分：苯扎氯胺0.1－5％，羟基丙基甲基纤维素0.5－5％，羟苯酸甲酯0.1－4％，去离子水30－96％。本发明苯扎氯胺避孕凝胶能使男女在性生活中，既可避孕又能彻底阻止性病感染，苯扎氯胺避孕凝胶符合世界卫生组织阴道用药的要求，无毒无害、无副作用、双向保护，药效长达24小时。
Description
技术领域：
本发明涉及药品，尤其是涉及快速杀灭多种性病病原体的苯扎氯胺避孕凝胶。
背景技术：
目前，随着人们生活水平的不断提高，大家对精神生活的追求越来越强烈。由于有些人的不良生活行为，利用安全套防意外怀孕的措施已经不能满足每个家庭的需要，另据有关专家报导，性病是传播艾滋病的大敌，艾滋病传播的途径之一是“性”。这已成了全世界紧迫且又不得不采取措施保护人类自己的重要问题。
发明内容：
本发明目的在于提供一种男女双方在性接触中既能轻松避孕又能防止性病传播的快速杀灭多种性病病原体的苯扎氯胺避孕凝胶。
本发明的目的是这样实现的：本发明提供了一种其中含有按重量百分比计的如下成分：
苯扎氯胺(Benzalkonium Chlordie)0.1-5％，
羟基丙基甲基纤维素 0.5-5％，
羟苯酸甲酯(Methyl paraden) 0.1-4％，
去离子水 30-96％。
快速杀灭多种性病病原体的苯扎氯胺避孕凝胶，其中还含有按重量百分比计的以下成分：
芦荟 1-10％和丙烯 0.1-5％。
快速杀灭多种性病病原体的苯扎氯胺避孕凝胶，为无色透明胶状粘稠体。
经中国医学科学院皮肤病研究所检测确认：本发明的快速杀灭多种性病病原体的苯扎氯胺避孕凝胶的浓度在1∶5时，作用2分钟，未见活动虫体，此浓度药液有较强的杀灭阴道毛滴虫的作用。苯扎氯胺避孕凝胶的浓度在1∶2与支原体悬液作用1分钟，即可杀灭解脲支原体。苯扎氯胺避孕凝胶的浓度在33.3％时，1分钟既能100％杀灭淋球菌。苯扎氯胺避孕凝胶的浓度经1∶2 和1∶3稀释作用1分钟，1∶4稀释作用3分钟，1∶5稀释作用5分钟，均可制动梅毒螺旋体。
本发明苯扎氯胺避孕凝胶能使男女双方在在性生活中，即可避孕又能彻底阻止性病感染，苯扎氯胺避孕凝胶符合世界卫生组织的要求，无毒无害、无副作用、双向保护，药效长达24小时。
实施例1：
a.将10kg苯扎氯胺与去离子水35kg混合在一起调和搅拌均匀得到混合物：
b.再将2kg羟基丙基甲基纤维素与5kg羟苯酸甲酯加入混合物调和搅拌成透明胶状粘稠体得到混合物；
c.将透明胶状粘稠体灌于经过消毒的备用容器中，经灌装机分别装入经过消毒的推进器中，即得成品。
实施例2：
a.将20kg苯扎氯胺与去离子水70kg混合在一起调和搅拌均匀得到混合物；
b.再将4kg羟基丙基甲基纤维素与10kg羟苯酸甲酯加入混合物调和搅拌成透明胶状粘稠体得到混合物；
c.将透明胶状粘稠体灌于经过消毒的备用容器中，经灌装机分别装入经过消毒的推进器中，即得成品。
实施例3：
a.将30kg苯扎氯胺与去离子水105kg混合在一起调和搅拌均匀得到混合物。
b.再将6kg羟基丙基甲基纤维素与15kg羟苯酸甲酯加入混合物调和搅拌成透明胶状粘稠体得到混合物。
c.将透明胶状粘稠体灌于经过消毒的备用容器中，经灌装机分别装入经过消毒的推进器中，即得成品。
Claims (3)
1、快速杀灭多种性病病原体的苯扎氯胺避孕凝胶。其特征在于：其中含有按重量百分比计的如下成分：
苯扎氯胺 0.1-5％，
羟基丙基甲基纤维素 0.5-5％，
羟苯酸甲酯 0.1-4％，
去离子水 30-96％。
2、权利要求1所述的快速杀灭多种性病病原体的苯扎氯胺避孕凝胶，其特征在于：其中还含有按重量百分比计的以下成分：
芦荟1-10％和丙烯0.1-5％。
3、权利要求1所述的快速杀灭多种性病病原体的苯扎氯胺避孕凝胶，为无色透明胶状粘稠体。
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|---|---|---|---|
| CN 200410088709 CN1634007B (zh) | 2004-11-01 | 2004-11-01 | 快速杀灭多种性病病原体的苯扎氯铵避孕凝胶 |
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| CN 200410088709 CN1634007B (zh) | 2004-11-01 | 2004-11-01 | 快速杀灭多种性病病原体的苯扎氯铵避孕凝胶 |
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| CN1634007A true CN1634007A (zh) | 2005-07-06 |
| CN1634007B CN1634007B (zh) | 2011-07-20 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214882A (zh) * | 2016-08-19 | 2016-12-14 | 吉安市御美丽健康产业股份有限公司 | 一种高强度抗菌液体凝胶及其制备方法 |
| CN109730985A (zh) * | 2019-03-27 | 2019-05-10 | 丹东欣时代生物医药科技有限公司 | 一种避孕凝胶的制作方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705187A (en) * | 1989-12-22 | 1998-01-06 | Imarx Pharmaceutical Corp. | Compositions of lipids and stabilizing materials |
| US6607716B1 (en) * | 1998-09-29 | 2003-08-19 | Tech Labs, Inc. | Pediculicidal compositions, a kit, and methods of use |
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- 2004-11-01 CN CN 200410088709 patent/CN1634007B/zh active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214882A (zh) * | 2016-08-19 | 2016-12-14 | 吉安市御美丽健康产业股份有限公司 | 一种高强度抗菌液体凝胶及其制备方法 |
| CN109730985A (zh) * | 2019-03-27 | 2019-05-10 | 丹东欣时代生物医药科技有限公司 | 一种避孕凝胶的制作方法 |
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| Publication number | Publication date |
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| CN1634007B (zh) | 2011-07-20 |
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Address after: 343100, No. 288, Beijing Jiulong Road, Jinggangshan economic and Technological Development Zone, Jiangxi Patentee after: Huang Linji Address before: 331200 No. 88 Jiangdong Road, Zhangshu City, Jiangxi Province Patentee before: Huang Linji |
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Application publication date: 20050706 Assignee: JI'AN CHEUNG KONG BIO-PHARMACEUTICAL Co.,Ltd. Assignor: Huang Linji Contract record no.: 2013360000048 Denomination of invention: Benzalkonium chloride contraceptive gel for quick eradication of multiple venereal disease pathogenic organism Granted publication date: 20110720 License type: Exclusive License Record date: 20130715 |
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