CN1613430A - Separated low-temperature tumor therapeutical equipments - Google Patents

Separated low-temperature tumor therapeutical equipments Download PDF

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Publication number
CN1613430A
CN1613430A CN 200410084732 CN200410084732A CN1613430A CN 1613430 A CN1613430 A CN 1613430A CN 200410084732 CN200410084732 CN 200410084732 CN 200410084732 A CN200410084732 A CN 200410084732A CN 1613430 A CN1613430 A CN 1613430A
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feed tube
vacuum
end cap
escape pipe
responsible
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CN 200410084732
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CN1256919C (en
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张鹏
齐守良
王如竹
许煜雄
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Shanghai Jiaotong University
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Shanghai Jiaotong University
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Abstract

A split-type low-temp therapeutic instrument for treating tumor is composed of a low-temp therapeutic segment consisting of front diffuser and thermoelectric couple, an insulating vacuum segment consisting of ring plug, internal and external vacuum tubes and vacuum chamber, a handle module consisting of air outlet tube and casing, and a liquid inlet module consisting of liquid inlet tube, locating block and sealing ring. Its front probe is disposable.

Description

Separated low-temperature tumor therapeutical equipments
Technical field
The present invention relates to a kind of low-temperature tumor therapeutical equipments, specifically is a kind of separated low-temperature tumor therapeutical equipments, belongs to the low temperature medical instruments field.
Background technology
Cryosurgery is to utilize cryotherapy to make a tissue injury so that a downright bad Clinical Science.Compare with the operation of traditional oncotherapy, cryosurgery has less, the no dose limitation of treatment side effect, the treatment cost is lower and advantage such as painful less that patient is caused, and can prevent that cancerous cell from spreading, and has to stop blooding and reduce hemorrhage effect.Cryosurgery often depends on the development of freezing apparatus.For the freezing treatment of in-vivo tissue tumor, mostly use the deep to thrust the formula probe.It can be divided into open and closed probe again.Open end of probe is open, and behind the insertion tissue, by the next airtight probe of solidifying of front end tissue, this method is not suitable for the bigger situation of pressure.And closed probe makes cryogenic liquid directly not contact with tissue, by the end of probe freezing tissue of sealing, thereby operates more convenient safety.For the in-vivo tissue tumor, closed end of probe thrusts method under the monitoring of ultrasonic, x-ray tomography imaging (CT) or nuclear magnetic resonance analyser imaging (MRI), can realize not operating on, Wicresoft gets involved, focus accurate positioning, success rate height, complication is few and the curative effect obvious effects.Closed cryoprobe was with 1961; the cold therapy instrument structure of American physician I.S Cooper invention is the typical case the most, and this therapeutic instrument is made up of a metal canula, in order to protect the percutaneous health tissues; except that tip portion,, circulate freezing tissue by liquid nitrogen all with the vacuum insulation protection.
Find through literature search prior art, the patent No. is: 92231553.1, name is called: tumor cold therapy pin, its structure is for being equipped with entering and discharge channel of liquid nitrogen in the needle tubing of a sealing, two passages are linked up at the needle point position, stretch out needle tubing from the backshank end, needle tubing and liquid nitrogen channel part have heat insulation layer.Yet these structures all are all-in-one-piece, and because the existence of vacuum structure, make process for machining and manufacturing very complicated, because the leakage and the material outgassing of weld seam, vacuum is difficult to keep the long period, therefore usually adopt the vacuum of living, reserve extraction valve, regularly find time.In addition, according to size, shape, position and the character of tumor often needs select the probe of different-diameter and length, this just needs to be equipped with and to safeguard a series of cold therapy instrument.Because the existence of vacuum structure makes the probe cost relatively more expensive, is difficult to realize disposable use, might cause interpatient cross infection, thereby need strict disinfectant program.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, proposed a kind of separate type low temperature apparats for treating tumor, make it can realize that the microtrauma percutaneous puncture goes into the tumor of in-vivo tissue and carry out freezing treatment.The present invention mainly is made up of low temperature therapy section, vacuum insulation section, Handleset and feed tube assembly four parts, and all by being threaded, very convenient assembling, and because the low temperature shrinkage characteristics of material makes firm and reliable connection, good seal performance.Disposable low temperature therapy section is cheap, simple in structure.
The present invention is achieved by the following technical solutions, the present invention includes: low temperature therapy section, vacuum insulation section, Handleset and feed tube assembly four parts.Its annexation is: from left to right, be followed successively by the low temperature therapy section, and the vacuum insulation section, Handleset and feed tube assembly, this four part is independent assembly, and its connected mode all is to be threaded.
The low temperature therapy section comprises: head bubbler and thermocouple that fine copper is made.The head bubbler is a hollow, and sharp-pointed sharp needle point is processed in the front portion, can directly thrust interior tissue, and afterbody is processed with female thread.Thermocouple is welded on head bubbler needle point place, is used for monitoring operation process tumor center temperature.
Described vacuum insulation section comprises: pipe in the ring taps, vacuum, vacuum outer tube, vacuum chamber left end cap, vacuum chamber housing, vacuum chamber right end cap.The ring taps front end has external screw thread, is used for being connected with the low temperature therapy section.Pipe in the ring taps, vacuum, the vacuum outer tube, the vacuum chamber left end cap, the vacuum chamber housing, the welding of vacuum chamber right end cap forms closing vacuum chamber, and getter is laid in inside.
Described Handleset is responsible for by escape pipe, the handle left end cap, and handle housing, adiabator, the handle right end cap, the escape pipe arm is formed.Escape pipe all has external screw thread about being responsible for, and is connected with the feed tube assembly with the vacuum insulation section respectively.By nut, left pad position fixing handle left end cap, right pad position right end cap, primary and secondary escape pipe welding UNICOM.Handle housing is fixed on the left and right end cap of handle by screw.Handle housing inside fills up adiabator.
Described feed tube assembly comprises: feed tube, politef locating piece, sealing ring, feed tube pad and feed tube clamp nut.From left to right successively politef locating piece, sealing ring, feed tube pad are enclosed within on the feed tube.Behind politef locating piece location, this assembly is inserted the Handleset escape pipe be responsible for, the feed tube insertion depth is adjustable.Utilize the feed tube clamp nut that the feed tube assembly is fixed on the Handleset escape pipe and be responsible for right-hand member.
The thermocouple of low temperature therapy section is drawn by feed tube.
The present invention can realize the disposable use of end of probe, and the closed ultrahigh vacuum adiabatic section that cost is relatively more expensive then can be recycled, and need not vaccum-pumping equipment and regularly finds time, and can keep more than 2 years, thereby reduce operation cost and maintenance cost greatly.What is more important, a vacuum insulation section can be used with the head bubbler of a plurality of models (length and diameter are different), and by regulating feed tube length, controls the ice hockey size flexibly, to adapt to the tumor of different sizes, position and character.
Description of drawings
Fig. 1 structural representation of the present invention
Fig. 2 low temperature therapy segment structure of the present invention sketch map
Fig. 3 vacuum insulation segment structure of the present invention sketch map
Fig. 4 Handleset structural representation of the present invention
Fig. 5 feed tube modular construction of the present invention sketch map
Wherein, low temperature therapy section 1, vacuum insulation section 2, Handleset 3, feed tube assembly 4, head bubbler 5, thermocouple 6, ring taps 7, pipe 8 in the vacuum, vacuum outer tube 9, vacuum chamber left end cap 10, vacuum chamber housing 11, getter 12, vacuum chamber right end cap 13, escape pipe is responsible for 14, handle left end cap 15, handle housing 16, adiabator 17, escape pipe arm 18, handle right end cap 19, feed tube 20, politef locating piece 21, sealing ring 22, feed tube pad 23.
The specific embodiment
As shown in Figure 1, the present invention includes: low temperature therapy section 1, vacuum insulation section 2, Handleset 3 and feed tube assembly 4.Its annexation is: from left to right, be followed successively by low temperature therapy section 1, and vacuum insulation section 2, Handleset 3 and feed tube assembly 4, its connected mode all is to be threaded.
As shown in Figure 2, described low temperature therapy section 1 is made of head bubbler 5 and thermocouple 6.Head bubbler 5 is a hollow, and sharp-pointed sharp needle point is processed in the front portion, and afterbody is processed with female thread.Head bubbler 5 needle point places are welded with thermocouple 6.
As shown in Figure 3, described vacuum insulation section 2 comprises: pipe 8 in the ring taps 7, vacuum, vacuum outer tube 9, vacuum chamber left end cap 10, vacuum chamber housing 11, getter 12, vacuum chamber right end cap 13.Ring taps 7 front ends have external screw thread, are used for being connected with low temperature therapy section 1.Pipe 8 in the ring taps 7, vacuum, vacuum outer tube 9, vacuum chamber left end cap 10, vacuum chamber housing 11,13 welding of vacuum chamber right end cap form closed cavity, and getter 12 back welding are laid in inside.Getter 12 is used for adsorbing the hydrogen that airborne nitrogen and material emit that bleeds.
As shown in Figure 4, described Handleset 3 is responsible for 14 by escape pipe, handle left end cap 15, handle housing 16, adiabator 17, escape pipe arm 18, handle right end cap 19.Escape pipe is responsible for about 14 all external screw thread, is connected with feed tube assembly 4 with vacuum insulation section 2 respectively.Escape pipe arm 18 welding escape pipes are responsible on 14, and mutual UNICOM.By nut, left pad position fixing handle left end cap 15, right pad position fixing handle right end cap 19.Handle housing 16 is fixed on handle left end cap 15 and the handle right end cap 19 by screw.Handle housing 16 inside fill up adiabator 17.
As shown in Figure 5, described feed tube assembly 4 comprises: feed tube 20, politef locating piece 21, sealing ring 22, feed tube pad 23.From left to right successively with politef locating piece 21, sealing ring 22, feed tube pad 23 is enclosed within on the feed tube 20.Behind politef locating piece 21 location, this assembly is inserted Handleset 3 escape pipes be responsible for 14, feed tube 20 passes escape pipe and is responsible for 14, and pipe 8 extends in head bubbler 5 cavities always in the vacuum, and its insertion depth is adjustable.Utilize the feed tube clamp nut that feed tube assembly 4 is fixed on Handleset 3 escape pipes and be responsible for 14 right-hand members.
Further describe implementation process of the present invention below in conjunction with accompanying drawing and example:
Every separate type low temperature apparats for treating tumor is furnished with a series of low temperature therapy section 1, length and diameter have nothing in common with each other, its typical structure as shown in Figure 2, each head bubbler 5 afterbody all has unified external screw thread, can cooperate with vacuum insulation section 2, head all is welded with thermocouple 6.
Vacuum insulation section 2 as shown in Figure 3, material is the high-quality rustless steel entirely, pipe 8 external diameter 2.5mm in the vacuum, vacuum outer tube 9 external diameter 5mm, wall thickness is all between 0.15~0.20mm.Can weld airtight bleeding point behind the evacuation after adding getter 12.
Handleset 3 as shown in Figure 4, handle left end cap 15, handle housing 16 and handle right end cap 19 are processed by bark pocket bakelite or fiberglass, behind the inner filling heat insulator 17, effect of heat insulation is fine, makes things convenient for the doctor hand-held or adopt other special fixture clampings location.
Fig. 5 is feed tube assembly 4 structure charts, and feed tube 20 is the high-quality stainless steel capillary, external diameter 1.0mm, wall thickness 0.15mm.Every separate type low temperature apparats for treating tumor is furnished with a series of feed tube 20, and its length has nothing in common with each other, can be according to the selected suitable feed tube 20 of the model of selected head bubbler 5.
Cryogenic liquid enters low temperature apparats for treating tumor inside through feed tube 20; until head bubbler 5 cavities; because head bubbler 5 does not have the vacuum insulation protection; cryogenic liquid can absorb the heat of tumor tissues and rapidly boiling, the tumor tissues temperature is reduced rapidly and is subjected to low temperature injury so that dead.Liquid-vapor mixture after the boiling flows back to by the narrow annular channel of 8 of pipes in feed tube 20 and the vacuum, because escape pipe is responsible for 14 right-hand members by 21 sealings of politef locating piece, liquid-vapor mixture is discharged by escape pipe arm 18 at last.Through focus, on head bubbler 5, form " ice hockey " of ultralow temperature by successive conveying liquid nitrogen stream, thus the kill tumor cell.
Low temperature therapy section 1 can realize disposable use, vacuum insulation section 2, and Handleset 3, can be recycled after simply sterilizing, thereby save the operation cost owing to directly do not contact with patient's tumor cell with feed tube assembly 4.Vacuum insulation section 2 adopts closed ultrahigh vacuum thermal insulation, can keep more than 2 years, need not to be equipped with vacuum pump, need not regularly to find time, and maintenance cost is low.Each vacuum insulation section 2 can cooperate with a series of head bubblers 5, need not to lay in many separate type low temperature apparats for treating tumor and just can carry out cryosurgery to the tumor of all size, position and character.Easy to use, only need storage capsule is connected with feed tube 20, can undergo surgery, and feed tube 20 insertion depths are adjustable.The highest 1.0Mpa that bears of pressure, working media are liquid nitrogen.
Above-mentioned advantage makes that the cost of manufacture of this therapeutic instrument is cheap, and is simple in structure flexible, compares with traditional integral formula low temperature medical apparatus and instruments, has very big competitive advantage, is applicable to large, medium and small type hospital clinical application.
With the foregoing description is example, the use that utilizes this separate type apparats for treating tumor to carry out freezing operation is described below: 1. under the monitoring of ultrasonic, x-ray tomography imaging (CT) or nuclear magnetic resonance analyser imaging (MRI), determine position, size and the shape of tumor.2. according to position, size and the shape of tumor, determine the model (mainly determining) of the head bubbler 5 of therapeutic instrument, select the feed tube 20 of respective length by length and external diameter.3. after connecing data collecting card after thermocouple 6 being drawn by feed tube 20, with head bubbler 5, the attaching nut, the feed tube clamp nut is tightened, and the assembling of separate type low temperature apparats for treating tumor finishes.With separate type low temperature apparats for treating tumor with after the cryogenic liquid hold-up vessel is connected, under the guiding of armour tubing, insert the tumor tissues that needs treatment, begin to carry out freezing.5. after operation finishes, low temperature therapy section 1 is abandoned, vacuum insulation section 2, Handleset 3 and feed tube assembly 4 are through simply reusing after the sterilization.
Melt fast and thermotherapy effect for reaching, need logical high temperature nitrogen sometimes.This separate type low temperature apparats for treating tumor is suitable equally, and a cryogenic liquid that need feed is converted to high temperature nitrogen and gets final product, and need not to carry out other transformations, and is very convenient reliable.

Claims (2)

1. separated low-temperature tumor therapeutical equipments, comprise: low temperature therapy section (1), vacuum insulation section (2), Handleset (3), feed tube assembly (4), it is characterized in that, low temperature therapy section (1), vacuum insulation section (2), Handleset (3) and feed tube assembly (4) are independent assembly, from left to right connect successively by screw thread, described low temperature therapy section (1) is made of head bubbler (5) and thermocouple (6), head bubbler (5) is a hollow, sharp-pointed sharp needle point is processed in the front portion, afterbody is processed with female thread, head bubbler (5) needle point place is welded with thermocouple (6), described vacuum insulation section (2) comprising: ring taps (7), pipe (8) in the vacuum, vacuum outer tube (9), vacuum chamber left end cap (10), vacuum chamber housing (11), getter (12), vacuum chamber right end cap (13), its annexation is: ring taps (7) front end has external screw thread, be used for being connected with low temperature therapy section (1), ring taps (7), pipe (8) in the vacuum, vacuum outer tube (9), vacuum chamber left end cap (10), vacuum chamber housing (11), vacuum chamber right end cap (13) welding forms closed cavity, the welding of getter (12) back is laid in inside, described Handleset (3) comprising: escape pipe is responsible for (14), handle left end cap (15), handle housing (16), adiabator (17), escape pipe arm (18), handle right end cap (19), its annexation is: escape pipe arm (18) welding escape pipe is responsible on (14), and mutual UNICOM, handle housing (16) is fixed on handle left end cap (15) and the handle right end cap (19), handle housing (16) inside fills up adiabator (17), described feed tube assembly (4) comprising: feed tube (20), politef locating piece (21), sealing ring (22), feed tube pad (23), its annexation is: from left to right successively with politef locating piece (21), sealing ring (22), feed tube pad (23) is enclosed within on the feed tube (20), behind politef locating piece (21) location, this assembly is inserted Handleset (3) escape pipe be responsible for (14), feed tube (20) passes escape pipe and is responsible for (14), pipe (8) in the vacuum, extend in head bubbler (5) cavity, feed tube assembly (4) is fixed on Handleset (3) escape pipe and is responsible for (14) right-hand member always.
2. by the described separated low-temperature tumor therapeutical equipments of claim 1, it is characterized in that escape pipe is responsible for about (14) all external screw thread, is connected with feed tube assembly (4) with vacuum insulation section (2) respectively.
CN 200410084732 2004-12-02 2004-12-02 Separated low-temperature tumor therapeutical equipments Expired - Fee Related CN1256919C (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101869507A (en) * 2010-06-21 2010-10-27 重庆大学 Cryosurgical scalpel for in vivo minimally invasive operation
CN101652107B (en) * 2007-01-31 2011-08-31 西克斯特姆生活有限公司 Dispensing device for pressurized containers for the application of cryogenic coolant
CN102488550A (en) * 2011-11-29 2012-06-13 浙江大学 Low-temperature therapeutic apparatus for tumour
CN107440783A (en) * 2017-09-19 2017-12-08 杜忠海 A kind of new insertion type probe for cold therapy of liver cancer
CN108498163A (en) * 2018-04-24 2018-09-07 海杰亚(北京)医疗器械有限公司 The vacuum interlayer treatment process of fission connection cryoablation needle
CN108498162A (en) * 2018-04-24 2018-09-07 海杰亚(北京)医疗器械有限公司 Fission connection cryoablation needle and its needle assembly and backshank component
CN108742825A (en) * 2018-06-15 2018-11-06 海杰亚(北京)医疗器械有限公司 Equipment and its SURGICAL NEEDLE THREADING DEVICE group for minimally invasive combination therapy
CN110507405A (en) * 2019-08-13 2019-11-29 上海导向医疗系统有限公司 The cryoablation needle of adjustable targeting district
CN111184561A (en) * 2019-06-13 2020-05-22 杭州心创医疗器械有限公司 Oocyte collector
CN111481286A (en) * 2020-04-23 2020-08-04 中国人民解放军陆军特色医学中心 Wart body freezing device

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101652107B (en) * 2007-01-31 2011-08-31 西克斯特姆生活有限公司 Dispensing device for pressurized containers for the application of cryogenic coolant
CN101869507A (en) * 2010-06-21 2010-10-27 重庆大学 Cryosurgical scalpel for in vivo minimally invasive operation
CN102488550A (en) * 2011-11-29 2012-06-13 浙江大学 Low-temperature therapeutic apparatus for tumour
CN102488550B (en) * 2011-11-29 2013-04-17 浙江大学 Low-temperature therapeutic apparatus for tumour
CN107440783B (en) * 2017-09-19 2019-10-11 杜忠海 A kind of insertion type probe for cold therapy of liver cancer
CN107440783A (en) * 2017-09-19 2017-12-08 杜忠海 A kind of new insertion type probe for cold therapy of liver cancer
CN108498163A (en) * 2018-04-24 2018-09-07 海杰亚(北京)医疗器械有限公司 The vacuum interlayer treatment process of fission connection cryoablation needle
CN108498162A (en) * 2018-04-24 2018-09-07 海杰亚(北京)医疗器械有限公司 Fission connection cryoablation needle and its needle assembly and backshank component
CN108498163B (en) * 2018-04-24 2020-07-28 海杰亚(北京)医疗器械有限公司 Vacuum interlayer treatment process for split connection cryoablation needle
CN108498162B (en) * 2018-04-24 2024-05-17 海杰亚(北京)医疗器械有限公司 Split-connection cryoablation needle, needle head assembly and needle tail assembly thereof
CN108742825A (en) * 2018-06-15 2018-11-06 海杰亚(北京)医疗器械有限公司 Equipment and its SURGICAL NEEDLE THREADING DEVICE group for minimally invasive combination therapy
CN108742825B (en) * 2018-06-15 2024-03-26 海杰亚(北京)医疗器械有限公司 Device for minimally invasive compound treatment and multifunctional surgical needle set thereof
CN111184561A (en) * 2019-06-13 2020-05-22 杭州心创医疗器械有限公司 Oocyte collector
CN110507405A (en) * 2019-08-13 2019-11-29 上海导向医疗系统有限公司 The cryoablation needle of adjustable targeting district
CN111481286A (en) * 2020-04-23 2020-08-04 中国人民解放军陆军特色医学中心 Wart body freezing device
CN111481286B (en) * 2020-04-23 2021-03-23 中国人民解放军陆军特色医学中心 Wart body freezing device

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