CN209316044U - A kind of cryoablation conduit - Google Patents

Abstract

Technical solutions of the utility model disclose a kind of cryoablation conduit, it include: freezing unit, control handle and connection unit, connection unit is connected to by the control handle with the freezing unit, the freezing unit includes sacculus, cold source circulation loop, wire leading pipe, air injection pipe and sheath, the proximal end of the sacculus is connect with the distal end of the air injection pipe, the distal end of the sacculus is connect with the distal end of the wire leading pipe, the cold source circulation loop is set in the sacculus, and the sheath is movably sheathed on the sacculus, the air injection pipe, on the wire leading pipe.The conduit of technical solutions of the utility model can pass through the deformation of the expansion effectively control cold source circulation loop of sacculus, realize the adherent conduction of cold source, to improve efficiency and guarantee the validity of cryoablation and the safety of product, pulmonary vascular resistance, which is effectively reduced, reduces pulmonary artery pressure.

Description

A kind of cryoablation conduit

Technical field

The utility model relates to medical instruments field more particularly to cryoablation conduits.

Background technique

Idiopathic pulmonary hypertension is a kind of serious progressive disease, with the progress of the state of an illness, the right side occurs and feels concerned about system pressure Power increase, pulmonary vascular resistance progressive increase, gradually develop to right heart failure and it is dead.The primary treatment of pulmonary hypertension at present Means are to improve existing organs except lungs obstruction by blood vessel dilatation drug, alleviate right heart insufficiency.But also some researches show that There are permanently effective responses to vasodilator for only 25~30% patients with pulmonary hypertension.In recent years, research confirms in master Pulmonary artery pressure can be effectively reduced in pulmonary artery row RF ablation, but cryoablation treatment pulmonary hypertension only resides within theory Level.

Currently, in the market there are two types of the Cryoablation systems of mainstream: one is the refrigeration systems of liquid refrigerant direct gasification System absorbs amount of heat by low temperature liquid refrigerant vapor, forms ultralow temperature around freezing region；Another kind is high pressure The refrigeration system of gaseous refrigerant throttling is imitated such as Argon-Helium Cryosurgery system by the throttling of argon gas using Joule-Thomson principle Low temperature should be generated, generates heating effect using the throttle effect of helium to realize gas heating.And both the above cryoablation system System is all based on cryogenic media and sprays release generation low temperature in sacculus, and balloon interior will generate larger negative during release It carries, common high molecular material is unbearable, and therefore, there are serious and uncontrollable risk factors for the system.

If Chinese patent 201511008633.8 discloses a kind of tumour cryoablation conduit, the conduit is defeated using refrigerant The intracapsular generation gasification heat absorption of goal forms low temperature, to kill cell tissue, reaches cryoablation purpose, but the structure freezes Performance is uncontrollable, without effective safety measure, and there are major hidden dangers.Chinese patent 201520045658.4, which discloses one kind, to be had The cryoablation foley's tube of guidewire lumen, the conduit are the freezing units being located in sacculus using refrigerant input, and with freezing Cold source is diffuseed to form centered on unit outward, cooling capacity is transmitted to by balloon wall and vascular wall by the transmitting medium in input sacculus It forms ice hockey, realizes cryoablation, structure cooling capacity transmitting is slower, and freezing performance is uncontrollable and loss is serious, cannot achieve The ablation of lower temperature.

Utility model content

The technical problem to be solved is that the safeties in use of cryoablation conduit for technical solutions of the utility model Low, cooling capacity transmits the problems such as relatively slow, freezing is uncontrollable, cryoablation low efficiency.

In order to solve the above technical problems, technical solutions of the utility model provide a kind of cryoablation conduit, which can By the deformation of the expansion effectively control cold source circulation loop of sacculus, the adherent conduction of cold source is realized, to improve efficiency and guarantee The validity of cryoablation and the safety of product, pulmonary vascular resistance, which is effectively reduced, reduces pulmonary artery pressure.

The cryoablation conduit of the utility model includes:

Freezing unit, the freezing unit include sacculus, cold source circulation loop, wire leading pipe, air injection pipe and sheath, the ball The proximal end of capsule is connect with the distal end of the air injection pipe, and the distal end of the sacculus is connect with the distal end of the wire leading pipe, this is practical new " connection " of type needs to guarantee that favorable sealing property, the cold source circulation loop are set in the sacculus, and the sheath is removable Ground is sheathed on the sacculus, the air injection pipe, on the wire leading pipe.It should be noted that " proximal end " described in the utility model Refer to one end close to operator, " distal end " refers to one end far from operator.

Preferably, the cold source circulation loop has shape memory function, and has first state and the second state, described First state is compressive state, and second state is after the balloon inflation, the cold source circulation loop restores to preboarding Recline the state of the sacculus when state.Thus, as the balloons are inflated, cold source circulation loop can restore to preset shape and be close to ball Cold source is transmitted to target site, realizes cryoablation by capsule inner wall.

Cold source circulation loop is arranged in the cryoablation conduit of the utility model, and refrigerant is not injected into sacculus, but It circulates in cold source circulation loop, there is no the risks of sacculus rupture, and there are two types of shapes for cold source circulation loop tool of the invention State, can recline balloon wall when it is restored to the second state from first state, and therefore, cold source can directly be passed by balloon wall It is delivered to target area, improves the efficiency of cryoablation.

Handle is controlled, the wire leading pipe connection including the handle connecting with the proximal end of the sheath and on the handle Seat, air injection pipe attachment base, the wire leading pipe attachment base are connect with the proximal end of the wire leading pipe, gas-guide tube and gas-guide tube attachment base group At the access that seal wire inputs, channel, the air injection pipe attachment base and the air injection pipe are established in vivo for subsidiary conduit Proximal end connection, the air injection pipe attachment base are equipped with gas injection joint, and gas injection joint is generally pumped with gas injection and connected, Jie in gas injection pump Matter is injected into sacculus by gas injection joint and air injection pipe, so that sacculus is along the laterally homogeneous expansion of wire leading pipe, general gas injection pump Medium be gas or liquid, suitable medium can be selected according to the needs of function or performance.

By the connection unit that is connected to the freezing unit of control handle, the connection unit include delivery pipe, Inlet suction port and return-air connector, the delivery pipe are connected to the cold source circulation loop, described inlet suction port one end with it is described defeated Pipe is sent to be connected to, the other end is connected to the delivery outlet of freezing equipment, and return-air connector one end is connected to the delivery pipe, the other end It is connected to the input port of freezing equipment, the cold source circulation loop is set by delivery pipe and inlet suction port and return-air connector with freezing The standby circuit for forming a closure, using the input and output of cryogenic media, to realize the refrigerating cycle of conduit.

One preferred embodiment of the utility model, the cold source circulation loop is one or more groups of petal-like structures, described Cold source circulation loop is arranged in rotational symmetry along the inner wall of the sacculus, so that cold source is recycled back to line route using the full expansion of sacculus Property revert to petal shape and be bonded the inner wall of sacculus, thus the rate of temperature fall of acceleration duct cold source, make cooling capacity transmitting more rapidly, More evenly, the shape and size of cold source circulation loop are controlled by controlling the state of sacculus, to realize to ablation areas Control.

One preferred embodiment of the utility model, the cold source circulation loop are along the sacculus axially around the spiral shell of setting Revolve shape structure.Work as balloon inflation, cold source circulation loop restore to helicoidal structure after closer to balloon wall and ablation tissue, meet The ablation demand of special target spot or special-shaped ablation areas, can be effectively controlled the transmitting of cooling capacity, accelerates cold source cool-down rate, makes cooling capacity Transmitting is more rapidly, more evenly and performance is controllable.In addition, the high-voltage resistance capability of the cold source circulation loop of helical structure is much higher than ball Capsule can avoid the security risk because of caused by balloon interior hypertonia.

Preferably, the wire leading pipe attachment base is by pushing or withdrawing the axial movement for controlling the wire leading pipe, to control Sacculus processed stretches, and then controls the shape of the sacculus.

One preferred embodiment of the utility model, the seal wire attachment base be equipped with retractable structure, the retractable structure with The proximal end of the wire leading pipe connects, and when retractable structure is in unstretched state, cold source circulation loop is first state, and wire leading pipe connects When joint chair is in tensional state, cold source circulation loop is the second state.

Preferably, the advance or recession of the sheath are realized by pushing or withdrawing the handle.

One preferred embodiment of the utility model, the sheath are connect with the handle threads, pass through the mutual of internal and external threads The displacement of sheath is realized in cooperation.

Described in the cooperation completion of one preferred embodiment of the utility model, the sheath and the handle by protrusion and groove The advance or recession of sheath.

One preferred embodiment of the utility model, the wire leading pipe and the air injection pipe are coaxial configuration, and the wire leading pipe is set In in the air injection pipe, the space between wire leading pipe and air injection pipe is the circulation passage of the medium in the injection sacculus, described Cold source circulation loop is set between the wire leading pipe and the air injection pipe.

One preferred embodiment of the utility model, the air injection pipe are independently arranged in the sheath with the wire leading pipe.

Preferably, angiography tube is equipped in the sheath, the distal end side wall of the sheath is equipped with remote with the angiography tube The adaptable hole in end, the distal end of the angiography tube are connect with described hole, and the handle is equipped with and is connected to the angiography tube Radiography pipe connections.

Traditional operation radiography mode is to need to withdraw angiography catheter after completing radiography function using angiography catheter Then cryoablation conduit is delivered to ablation areas by delivery sheath by human body, operating process is cumbersome and in cryoablation Conduit input after human body can not radiography again, in addition, since the leakproofness for being bonded ablation tissue after detection balloon inflation also needs To increase delivery sheath outside cryoablation conduit, pass through Jie of the gap of delivery sheath and cryoablation conduit injection detection The overall dimensions of matter, a whole set of surgical instrument are bigger than normal, limit the use of cryoablation conduit.And the utility model passes through cold Freeze and angiography tube be set inside ablation catheter, contrast medium is injected by angiography tube and radiography pipe connections, realizes radiography function, It is able to detect the sealing performance of balloon occluder simultaneously, optimizes design size, reduce surgical procedure process and uses the time, and expands Big application field.

Detailed description of the invention

Fig. 1 is the structural schematic diagram of the cryoablation conduit of the utility model embodiment 1；

Fig. 2 is the structural schematic diagram of the cold source circulation loop of the utility model embodiment 1；

Fig. 3 is the top view of the cold source circulation loop of the utility model embodiment 1；

Fig. 4 is the structural schematic diagram of the seal wire attachment base (unstretched state) of the utility model embodiment 1；

Fig. 5 is the structural schematic diagram of the seal wire attachment base (tensional state) of the utility model embodiment 1；

Fig. 6 is the sheath of the utility model embodiment 1 and the attachment structure schematic diagram of handle；

Fig. 7 is the sheath of the utility model embodiment 1 and another attachment structure schematic diagram of handle；

Fig. 8 is the distribution figure of the wire leading pipe of the utility model embodiment 2, air injection pipe and cold source circulation loop；

Fig. 9 is the structural schematic diagram of the cold source circulation loop of the utility model embodiment 3；

Figure 10 is the structural schematic diagram of the cold source circulation loop of the utility model embodiment 3；

Figure 11 is the structural schematic diagram of the angiography tube of the utility model embodiment 4；

Figure 12 is the structural schematic diagram of the angiography tube of the utility model other embodiments.

Specific embodiment

Technical solutions of the utility model are described in detail below with reference to embodiment.

Embodiment 1

As shown in Figure 1, the cryoablation conduit of the utility model embodiment includes freezing unit 1, control handle 2 and connection Unit 3.

Freezing unit 1 includes sacculus 11, cold source circulation loop 12, wire leading pipe 13, air injection pipe 14 and sheath 15, sacculus 11 Proximal end is connect with the distal end of air injection pipe 14, and the distal end of sacculus 11 is connect with the distal end of wire leading pipe 13, and cold source circulation loop 12 is set to In sacculus 11, sheath 15 is movably sheathed on sacculus 11, air injection pipe 14, on wire leading pipe 13.

In the present embodiment, cold source circulation loop 12 has shape memory function, and has first state and the second state, First state is compressive state, and the second state is after sacculus 11 expands, and cold source circulation loop 12 reclines when restoring to predetermined form The state of sacculus 11, the cold source circulation loop in Fig. 1 are the second state.

It controls handle 2 and includes wire leading pipe attachment base 21, air injection pipe attachment base 22 and handle 23, wherein wire leading pipe attachment base 21, air injection pipe attachment base 22 is set on handle 23, and handle 23 is connect with the proximal end of sheath 15, wire leading pipe attachment base 21 and wire leading pipe 13 proximal end connection, wire leading pipe 13 and wire leading pipe attachment base 21 constitute the access of seal wire input, in vivo for subsidiary conduit Channel is established, air injection pipe attachment base 22 is connected to the proximal end of air injection pipe 14, and air injection pipe attachment base 22 is equipped with gas injection joint, gas injection Connector is generally pumped with gas injection and is connected, and the medium in gas injection pump is injected into sacculus 11 by gas injection joint and air injection pipe 14, so that Sacculus 11 is along the laterally homogeneous expansion of wire leading pipe 13.

Connection unit 3 be connected to by controlling handle 2 with freezing unit 1, it is main including delivery pipe 31, inlet suction port 32 and time Gas connector 33, delivery pipe 31 are connected to cold source circulation loop 12, and 32 one end of inlet suction port is connected to delivery pipe 31, the other end with it is cold Freeze the delivery outlet connection of equipment, 33 one end of return-air connector is connected to delivery pipe 31, and the other end is connected to the input port of freezing equipment, Cold source circulation loop 12 forms returning for a closure by delivery pipe 31 and inlet suction port 32 and return-air connector 33 and freezing equipment Road, using the input and output of cryogenic media, to realize the refrigerating cycle of conduit.

In conjunction with Fig. 2 and Fig. 3, cold source circulation loop 12 is one or more groups of petal-like structures, and cold source circulation loop 12 is along ball The inner wall of capsule 11 is arranged in rotational symmetry, keeps cold source circulation loop 12 petal by linear restoring using the full expansion of sacculus 11 Shape and the inner wall for being bonded sacculus 11, so that the rate of temperature fall of acceleration duct cold source, makes cooling capacity transmitting more rapidly, more evenly, pass through The state of sacculus 11 is controlled to control the shape and size of cold source circulation loop 12, to realize the control to ablation areas.

Wire leading pipe 13 and air injection pipe 14 are coaxial configuration, and wire leading pipe 13 is set in air injection pipe 14, wire leading pipe 13 and air injection pipe Space between 14 is the circulation passage of the medium injected in sacculus 11, and cold source circulation loop 12 is set to wire leading pipe 13 and air injection pipe Between 14.

Wire leading pipe attachment base 21 controls the axial movement of wire leading pipe 13 by pushing or withdrawing, so that sacculus 11 is flexible, And then control the shape of sacculus 11.

In conjunction with Fig. 4 and Fig. 5, in the present embodiment, seal wire attachment base 21 is equipped with retractable structure, retractable structure and seal wire The proximal end of pipe 13 connects, as shown in figure 4, cold source circulation loop 12 is first state when retractable structure is in unstretched state.Such as Shown in Fig. 5, when wire leading pipe attachment base 21 is in tensional state, cold source circulation loop 12 is the second state.

The advance of sheath 15 is realized with returning back through to push or withdraw handle 23, as shown in fig. 6, the sheath of the present embodiment 15 are threadedly coupled with handle 23, and the displacement of sheath 15 is realized by the mutual cooperation of internal and external threads.Certainly, it can also be tied by other Structure is realized, as shown in fig. 7, sheath 15 is equipped with protrusion, handle 23 is equipped with groove, and sheath is completed in the cooperation for passing through protrusion and groove The advance or recession of pipe 15.

Embodiment 2

Unlike the first embodiment, the wire leading pipe 13 of the present embodiment, air injection pipe 14 and cold source circulation loop 12 are in sheath 15 Inside it is set side by side.As shown in figure 8, air injection pipe 14 is arranged on 13 side of wire leading pipe, transmitting medium is direct by air injection pipe 14 Sacculus 11 is injected, sacculus 11 is expanded, cold source circulation loop 12 tends to expand, and reverts to the petal shape of preboarding.Sacculus 11 The degrees of expansion that cold source circulation loop 12 can be limited controls the shifting of wire leading pipe 13 by pushing or withdrawing wire leading pipe attachment base 21 Position, may be implemented the control to 11 shape of sacculus, and then become cold source circulation loop 12 between the first state and a second state It changes, closer to balloon wall and ablation tissue after the recovery preset shape of cold source circulation loop 12.

Embodiment 3

In conjunction with Fig. 9 and Figure 10, the present embodiment the difference from example 2 is that cold source circulation loop 12 structure.This implementation The cold source circulation loop 12 of example is helicoidal structure, and along 11 axial rings of sacculus around setting.Connected by pushing or withdrawing wire leading pipe Joint chair 21 controls the displacement of wire leading pipe 13, the control to 11 shape of sacculus may be implemented, and then limit cold source circulation loop 12 Degrees of expansion converts cold source circulation loop 12 between the first state and a second state, and cold source circulation loop 12 restores default Closer to balloon wall and ablation tissue after shape.

Embodiment 4

As shown in figure 11, the present embodiment is provided with angiography tube 16, the distal end side wall of sheath 15 in the sheath 15 of embodiment 1 It is equipped with the hole adaptable with the distal end of angiography tube 16, the distal end of angiography tube 16 is connect with hole, and handle 23 is equipped with and makes The medium for being used to detect is injected ball by the contrasted pipe 16 of radiography pipe connections 24 by the radiography pipe connections 24 that shadow pipe 16 is connected to Whether 11 proximal end of capsule penetrates tissue by the medium of equipment observation detection, judges its leakproofness, so that it is guaranteed that freezing performance Well, by 16 injected media of angiography tube can real-time monitoring freeze situation, be more convenient for doctor or operator grasp the information of freezing.

As shown in figure 12, in other embodiments, angiography tube 16, angiography tube can also be set in the sheath 15 of embodiment 3 16 set-up mode is consistent with embodiment 4.

Below by taking the cryoablation conduit of embodiment 4 as an example, its working principle is described in detail, the work of other embodiments is former It manages substantially similar with embodiment 4.

Seal wire is sent into lesion tissue to be ablated along body passageway by operation consent, and guiding wire leading pipe 13 along seal wire will Freezing unit 1 is sent to ablation tissue region.Radiography pipe connections 24 are connect with angiography tube 16 and are injected contrast medium, by setting Standby observation and the shapes and sizes for measuring region to be ablated, in order to the optimal freezing parameter of determination.Then, gas injection is pumped and is infused The medium of the connection of tracheae attachment base 22 and injected media, injection can be gas or liquid or other media.The medium of injection is through infusing Tracheae 14 is inputted with Filled Balloon 11, makes sacculus 11 along the laterally homogeneous expansion of wire leading pipe 13, since cold source circulation loop 12 has Memory function, when sacculus 11 expands, cold source circulation loop 12 can restore preset shape, final to be bonded 11 inner wall of sacculus.Operation Wire leading pipe attachment base 21 drive wire leading pipe 13 withdraw, with adjust sacculus 11 expand after shape, and then by sacculus 11 limit it is cold The shape of source circulation loop 12, and adjustment appropriate is carried out to sacculus 11 according to the measurement result of ablation areas radiography, to guarantee Size adjustable and performance are controllable.After the full expansion of sacculus 11, the fitting of sacculus 11 is set to block the group being ablated to by driving handle 23 It knits, the medium for being used to detect is injected into 11 proximal end of sacculus by the contrasted pipe 16 of radiography pipe connections 24, is observed and is examined by equipment Whether the medium of survey penetrates tissue, judges its leakproofness, so that it is guaranteed that freezing performance is good.It is injected and is situated between by angiography tube 16 Matter can real-time monitoring freeze situation, be more convenient for doctor or operator grasp the information of freezing.

When starting freezing function, cryogenic media is inputted by inlet suction port 32, through delivery pipe 31 and cold source circulation loop 12 And it is close to when cryogenic media reaches cold source circulation loop 12 distal end for reaching the refrigerating cycle circuit 12 being located in sacculus 11 It is exported after the tissue heat exchange of balloon wall, the medium of output inputs cold through cold source circulation loop 12, delivery pipe 31, return-air connector 33 Freeze in equipment or air.Freezing function is closed, closes rewarming function after carrying out in due course rewarming, interior negative pressure of taking out is pumped for ball by gas injection Medium pumpback in capsule 11, and pushing sheath tube 15 makes cold source circulation loop 12 and sacculus 11 withdraw sheath to distal end spacing place In 15, freezing unit is then withdrawn by human body by control handle 2, completes cryoablation.

Specific embodiment of the utility model is described in detail above, it should be understood that those skilled in the art without It needs creative work according to the present utility model can conceive and makes many modifications and variations.Therefore, it is all in the art Technical staff passes through logical analysis, reasoning, or a limited experiment according to the design of the utility model on the basis of existing technology can It, all should be within the scope of protection determined by the claims with obtained technical solution.

Claims (10)

1. a kind of cryoablation conduit characterized by comprising

Freezing unit, the freezing unit include sacculus, cold source circulation loop, wire leading pipe, air injection pipe and sheath, the sacculus Proximal end is connect with the distal end of the air injection pipe, and the distal end of the sacculus is connect with the distal end of the wire leading pipe, the cold source circulation Circuit is set in the sacculus, and the sheath is movably sheathed on the sacculus, the air injection pipe, on the wire leading pipe；

Handle is controlled, the control handle includes the handle connecting with the proximal end of the sheath and the seal wire on the handle Pipe attachment base, air injection pipe attachment base, the wire leading pipe attachment base are connect with the proximal end of the wire leading pipe, the air injection pipe attachment base It is connected to the proximal end of the air injection pipe, the air injection pipe attachment base is equipped with gas injection joint；

The connection unit being connected to by the control handle with the freezing unit, the connection unit includes delivery pipe, air inlet Connector and return-air connector, the delivery pipe are connected to the cold source circulation loop, described inlet suction port one end and the delivery pipe Connection, the other end is connected to the delivery outlet of freezing equipment, and return-air connector one end is connected to the delivery pipe, the other end with it is cold Freeze the input port connection of equipment.

2. cryoablation conduit as described in claim 1, which is characterized in that the cold source circulation loop have first state and Second state, the first state are compressive state, and second state is the cold source circulation loop after the balloon inflation Recline the state of the sacculus when restoring to predetermined form.

3. cryoablation conduit as claimed in claim 2, which is characterized in that the cold source circulation loop is one or more groups of flowers Valvular structure is the helicoidal structure along the sacculus axial direction around setting.

4. cryoablation conduit as described in claim 1, which is characterized in that the wire leading pipe attachment base is by pushing or withdrawing The axial movement of the wire leading pipe is controlled, and then controls the shape of the sacculus.

5. cryoablation conduit as claimed in claim 4, which is characterized in that the seal wire attachment base is equipped with retractable structure, The retractable structure is connect with the proximal end of the wire leading pipe.

6. cryoablation conduit as described in claim 1, which is characterized in that by pushing or withdrawing described in the handle realization The advance or recession of sheath.

7. cryoablation conduit as claimed in claim 6, which is characterized in that the sheath is connect with the handle threads.

8. cryoablation conduit as claimed in claim 6, which is characterized in that the sheath and the handle by protrusion with it is recessed The advance or recession of the sheath are completed in the cooperation of slot.

9. cryoablation conduit as described in claim 1, which is characterized in that the wire leading pipe is set in the air injection pipe, institute State cold source circulation loop be set between the wire leading pipe and the air injection pipe or the air injection pipe with the wire leading pipe described It is independently arranged in sheath.

10. cryoablation conduit as described in claim 1, which is characterized in that be equipped with angiography tube, the sheath in the sheath Distal end side wall be equipped with the hole adaptable with the distal end of the angiography tube, the distal end of the angiography tube and described hole connect It connects, the handle is equipped with the radiography pipe connections being connected to the angiography tube.