CN2544689Y - B-ultrasonic location multi-cold-needle puncture internal tumor cryotherapy apparatus - Google Patents

B-ultrasonic location multi-cold-needle puncture internal tumor cryotherapy apparatus Download PDF

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CN2544689Y
CN2544689Y CN 02220581 CN02220581U CN2544689Y CN 2544689 Y CN2544689 Y CN 2544689Y CN 02220581 CN02220581 CN 02220581 CN 02220581 U CN02220581 U CN 02220581U CN 2544689 Y CN2544689 Y CN 2544689Y
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temperature
cold
unit
liquid nitrogen
low
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郁如煌
张新华
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Abstract

The utility model discloses a type-B ultrasonic positioning multi-freezing probe puncture in vivo tumor hypothermia treatment machine, which is characterized in that the hypothermia treatment machine includes a liquid storage unit, a transfusion unit, a slender-typed freezing probe unit, a freezing probe tip melting unit, an intelligent temperature control unit, a display control unit and a digital operation display screen unit. The utility model has the advantages that the utility model carries out the positioning by the type-B ultrasonic guide, the hypothermia freezing treatment is carried out by multi-freezing probe percutaneous puncture of liver cancer and other deep tumors, so as to realize the purpose of carrying out the hypothermia surgical treatment of the human deep tumors and middle and advanced stages of cancers without the open surgery; the flexibility of a liquid nitrogen transmission pipe is good, and the cold loss of the liquid nitrogen flow of the transmission pipe is reduced by using the high vacuum thermal insulation mode; the freezing probe adopts a liquid nitrogen flow channel with vacuum thermal insulation, the channel transmits the liquid nitrogen to the tip of the freezing probe, the control of the liquid nitrogen flow rate by the freezing probe can provide the flexibility for the matching of a sculpture ice ball and an anatomical structure.

Description

Low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic location
One. technical field
The utility model relates to a kind of is cold-producing medium with liquid nitrogen (--196 ℃), and multi-cold-needle is by B ultrasonic guiding location, percutaneous puncture deep layer tumor to the bodies such as hepatocarcinoma, the cryosurgery apparatus that carries out the cryosurgery treatment.
Two. background technology
Since Cooper in 1961 starts the liquid nitrogen cryotherapy device, obtained remarkable result by clinical treatment, caused the very big interest and the attention of medical circle.In the last thirty years, along with technological progress, a new-type therapy---cryosurgery is widely used in clinical each section successively.Current in China, though medical refrigeration popularization and application in the cold therapy of the shallow surface diseases of health such as skin carcinoma, bolt for fastening a door from outside flat wart, nasal polyp, cervical erosion, and also tumor cold therapies such as fritter hepatocarcinoma have been obtained certain effect with the surface contact, but because the restriction of prior art and equipment, at present China is to the treatment of freezing of deep layer tumor, large tracts of land tumor and middle and terminal cancer, also is in only a few hospital and doing among clinical trial explores.Existing patented technology " the comprehensive cold therapy of liver cancer device of spininess " (ZL patent No. 96220269X), it is under the state that cuts abdominal cavity exposure liver, liquid nitrogen flows to many cold probes by single pipe by tap and penetrates into liver tumor, carries out cryosurgical treatment.This achievement in research shows, the cryosurgery technique with the apparatus level of China has striden forward a step, but because of its employing is not the liquid-transport pipe-line of vacuum heat-insulation, cold probe also not tool every cold function, big and the cold probe of not only cold damage is difficult to avoid cold injury not need refrigerated tissue during operation, influence is freezed accurately and effectiveness cancer cell tissue, and the technical pattern of its apparatus is also still advanced inadequately.The shortcoming of its maximum is in addition, and operation must will be cut the abdominal cavity and just can be carried out, and does not promptly operate on just can't undergo surgery.And the mode of taking not operate on is carried out the cryosurgery treatment to deep layer tumor and middle and terminal cancer in the body, and is also impossible in China at present.
The vacuum heat-insulation liquid nitrogen carrier pipe in the cryosurgical engineering of product grinds in existing China, though outer tube is a rustless steel ripple flexible pipe, and internal lining pipe is selected for use is that thin rustless steel hard tube (China still lacks the corrugated stainless steel tubing production and supply of special thin specification so far) is made, this liquid nitrogen carrier pipe oar extreme difference uses the other foot of other hands.What cryosurgical engineering adopted in addition all still is the instrument and meter of transistor line and pointer-type, compares with current digital age technology, and oneself seems very backward.
Three, summary of the invention
1. goal of the invention: the purpose of this utility model is the deficiency that exists at prior art, comprehensively take new technical means, design a kind of B ultrasonic location multi-cold-needle puncture in-vivo tumour hypothermia therapy unit, just can carry out the cryosurgery treatment deep layer tumor and middle and terminal cancer in the body to realize to operate on.
2. technical scheme: realize that the technical solution of the utility model is: low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of a kind of B ultrasonic location is characterized in that this hypothermia therapy unit comprises storage liquid unit, transfusion unit, slender type cryoprobe unit, cold needle tip thawing unit, intelligent temperature control unit, shows control unit and Numeral operation display screen unit; Wherein storing the liquid unit comprises from supercharging discharge opeing Dewar type container; Transfusion unit comprises low-temperature solenoid valve, liquid nitrogen carrier pipe probe active interface; Slender type cryoprobe unit comprises cryoprobe, air vent, thermocouple changeover plug; Cold needle tip thawing unit comprises microminiature high-pressure nitrogen bottle, decompressor, electromagnetic valve, nitrogen heat exchanger; The intelligent temperature control unit comprises the thermocouple that is installed in the cryoprobe tip, the digital temperature controller of the intelligent low-temperature that links to each other with thermocouple, lesion tissue thermometric needle; Show the control unit and comprise B ultrasonic and computer; The Numeral operation display screen unit comprises charactron, display screen, operation push-button etc.Center discharge pipe in supercharging discharge opeing Dewar type container is connected with the liquid nitrogen carrier pipe by low-temperature solenoid valve, the end of liquid nitrogen carrier pipe connects the probe active interface, cryoprobe is connected on the probe active interface, and the air inlet electromagnetic valve that the high-pressure nitrogen bottle escape pipe communicates with the top bypass duct side of liquid nitrogen carrier pipe after by decompressor, electromagnetic valve, nitrogen heat exchanger is connected.
Storage liquid unit also comprises feed liquor valve, capacitance sensor and digital liquidometer, and digital liquidometer is connected with capacitance sensor.
Storage liquid unit also comprises pressure charging valve, adjust blood pressure regulator, safety anti-explosive device, Pressure gauge, atmospheric valve, acoustic filter and the air vent that is connected successively with Dewar type container.
Liquid nitrogen carrier pipe in the transfusion unit has two, and every is the inside and outside fine vacuum multilayer insulation liquid nitrogen carrier pipe that is made of metal hose.
Twin-channel liquid nitrogen carrier pipe, active interface, cryoprobe and air vent in the transfusion unit and cold needle tip thawing unit constitute the hot nitrogen channel loop.
Cold needle tip thawing unit also comprises the intelligent digital temperature controller.
The intelligent temperature control unit also comprises the digital display instrument of low temperature, and the digital display instrument of this low temperature is connected with many root tissues of focus thermometric needle by changeover plug.
The intelligent temperature control unit comprises that also cooling freezes the Elapsed Time Code Generator of time-delay.
Storage liquid unit is by regulating elements such as voltage stabilizing and safety anti-explosive device and constitute from supercharging discharge opeing Dewar type container, the digital display instrument of liquid level, pressure; Employing can save thermal resistance is set in Dewar type container in the traditional structure, or external steel cylinder gas is pressurizeed the burden of discharge opeing from supercharging discharge opeing Dewar type container storage liquid.But the liquid nitrogen capacity in the digital display instrument direct-reading of the capacitance type liquid level Dewar type container monitors the liquid nitrogen consumption simultaneously in order to avoid excessive during the filling liquid nitrogen in the cryosurgery process.In the pipeline that prolongs behind the Dewar type container pressure charging valve, decompression regulator, Pressure gauge, relief valve are housed, the gas of superpressure discharges pressure release automatically by relief valve, and Dewar type container and work safety are guaranteed in the automatic explosion of rupture pressure disc when meeting accident.
Transfusion unit is made of the rustless steel liquid nitrogen carrier pipe that is installed in the dual pathways (two) the fine vacuum multilayer insulation in the Dewar type container outlet and top low-temperature solenoid valve thereof, terminal active interface.The pipeline of fine vacuum multilayer insulation can farthest reduce the boil-off of liquid nitrogen in flow process.It is the thin rustless steel ripple of 2mm flexible pipe that this utility model has been selected special internal diameter for use, replaces rustless steel hard tube commonly used in the past and does internal lining pipe, the oar of liquid nitrogen carrier pipe is greatly improved, thereby made things convenient for operation, can change the treatment angle arbitrarily.Active interface on the liquid nitrogen carrier pipe end is used for changing fast and is connected a plurality of slender type cryoprobes.
Slender type cryoprobe unit is the core technology device that percutaneous puncture to deep layer tumor carries out the cryosurgery treatment, for obtaining the excision of target cancerous tissue, cryoprobe adopts the liquid nitrogen flow channel of vacuum heat-insulation, this passage is transported to the cryoprobe tip with liquid nitrogen, and can mate mutually for " engraving " ice hockey and anatomical structure the control of the liquid nitrogen flow rate by cryoprobe provides motility.Tiny and consistent cold needle handle portion and tip diameter make tissue injury reduce to minimum degree and probe are inserted easily.In order to enlarge the application of new type low temperature surgical instruments, the cold pin of slender type is taked the seriation design, and outside dimension is from 2mm-5mm; Length has 12 kinds of specifications from 18cm-40cm.
Cryoprobe is welded by three elongated stainless steel capillary intussusceptions.Manufacture difficulty is very big, and especially external diameter only is the cryoprobe of the special thin specification of 2mm.The outside is a vacuum interlayer between two.Innermost one is the liquid nitrogen spray pipe, is ejected into cold nitrogen after the liquid nitrogen heat exchange vaporization of cold needle tip from vacuum interlayer inwall and liquid nitrogen spray pipe seam crack (loop), the emptying of self cooling Aculeata exhaustor.By the globe joint that cold Aculeata can be connected fast with the active interface of liquid nitrogen carrier pipe, two cold pins of once dismantled and assembled replacing can freeze to comprehensive puncture to a plurality of cold pin in the destination organization so in batches, with the freezing efficiency of assurance cryosurgery.The thermocouple wire of monitoring probe tip temperature also passes from this slit, links to each other with intelligent digital low temperature monitor controller by miniature slotting Cuo.The elongated cryoprobe of the seriation all size that 18-40cm is long, freezing zone is (most advanced and sophisticated sealing) only at its most advanced and sophisticated 1-4cm place, other position is under the vacuum heat-insulation effect, still be in the room temperature state, when cryoprobe percutaneous puncture during to the deep layer tumor, consequently the destination organization excision only is accompanied by the minimum risk of adjacent tissue or the damage of device palace like this.
Cold needle tip thawing unit is made of two microminiature nitrogen cylinders, decompressor, electromagnetic valve, nitrogen heat exchanger, intelligent digital temperature controller and two air inlet electromagnetic valves.Be preheating to about 150 ℃ band press nitrogen by the air inlet electromagnetic valve by liquid nitrogen carrier pipe top bypass duct, lead to the liquid nitrogen carrier pipe and flow to cold needle tip, the tip is rapidly heated breaks away from the destination organization that is frozen into ice hockey.This root liquid nitrogen carrier pipe plays the effect of gas, the coaxial double flow channel of liquid, makes its structure more rationally compact.
The intelligent temperature control unit is by being installed in the thermocouple in the cryoprobe tip, two digital temperature controllers of intelligent low-temperature, and many root tissues thermometric needle, two digital display instruments of low temperature and the Elapsed Time Code Generator for the freezing time-delay of setting constitute.The digital temperature controller of intelligent low-temperature links to each other with the low-temperature solenoid valve at liquid nitrogen carrier pipe top, freezing time-delay Elapsed Time Code Generator, treatment temperature and time by predefined cryoprobe tip, drive and close low-temperature solenoid valve, make the cryoprobe tip in the cooling time of setting, relatively stable on the treatment temperature value that sets.The low temperature number display instrument that digital temperature controller of intelligent low-temperature and the thermometric needle in penetrating into destination organization link to each other can be observed the destination organization center and lip temperature and the rate of temperature fall that are frozen at any time.The destination organization lip temperature finally must reach-50 ℃ (the proof cancerous cell is killed), otherwise must prolong freeze-off time.
External colored B ultrasonic and computer show the control unit, be after detecting the accurate position of destination organization by the B ultrasonic ultrasound probe, many cryoprobe percutaneous are penetrated into the destination organization center, simultaneously with several edges of organizing thermometric needle to penetrate into the destination organization center, the computer software of design makes the computer display control device that is connected with colored B ultrasonic, shows each cryoprobe, organizes thermometric needle in in-house storing by image; Monitor the fluid activity that each cryoprobe liquid nitrogen stream is threaded a pipe; Monitor each cryoprobe, organize the thermocouple of thermometric needle, to guarantee each probe temperature---show in the time of the time relationship image; Patient counts a tree name data and is transfused to and is stored in and be used for the needs that hospital's retaining case is in the future called in the system.
The Numeral operation display screen is that all displays temperatures of intelligence instrument, the charactron of time and color touch formula operation push-button are installed concentratedly on the casing operating display, is convenient to the patient and operates various several a tree name situations of change directly perceived.
3. beneficial effect:
(1). by B ultrasonic guiding location, deep layer tumors such as multi-cold-needle percutaneous puncture hepatocarcinoma are carried out the freezing treatment, have realized not operating on human body deep layer tumor and middle and terminal cancer are carried out the purpose that cryosurgery is treated;
(2). select for use internal diameter only to be the special corrugated stainless steel tubing internal lining pipe of 2mm, liquid nitrogen carrier pipe oar in the cryosurgery apparatus of making is good, also, the mobile cold loss of carrier pipe liquid nitrogen is reduced, improved the refrigerating efficiency of cold needle tip greatly because taked the high vacuum insulation mode;
(3). seriation slender type cryoprobe adopts the liquid nitrogen flow channel of vacuum heat-insulation, this passage is transported to the tip of cryoprobe with liquid nitrogen, can improve motility for " engraving " ice hockey and anatomical structure are complementary to the control of the liquid nitrogen flow rate by cryoprobe.Tiny and consistent cold needle handle portion and tip diameter make tissue injury be reduced to minimum degree and probe are inserted easily.The thinnest a kind of cryoprobe of the present utility model, external diameter is 2mm, long 18cm, has reached world today's highest level;
(4) dual pathways (two) liquid nitrogen carrier pipe automatic control transfusion and with the quick dismounting mode that is connected of the cold pin active interface of slender type, can be in advance by the B ultrasonic location, 2-8 the cold pin that percutaneous penetrates into destination organization rotated freeze thawing and operated;
(5). press heated nitrogen by liquid nitrogen carrier pipe (becoming gas, the coaxial double flow channel of liquid) with band, cold needle tip is carried out thawing, make cold pin throw off the destination organization that forms ball fast, this is to the significant improvement of tradition with thermal resistance rewarming (fragile) frame mode;
(6). by revising the Refrigeration Technique parameter, make the destination organization lip temperature finally drop to effective low temperature (50 ℃) of kill cancer cell, thereby the success that has ensured cryosurgery is effective.
(7). adopt intelligent temperature controller, computer shows control and the Numeral operation display screen comes the monitoring low temperature operation.
Four, description of drawings
Accompanying drawing is a structural principle sketch map of the present utility model.
Five. the specific embodiment:
Referring to accompanying drawing, this utility model is made up of seven construction units.They are by the storage liquid unit of forming from supercharging discharge opeing Dewar type container 1, center outlet tube 2, feed liquor valve 3, capacitance sensor 4, digital liquidometer 5, pressure charging valve 6, adjust blood pressure regulator 7, safety anti-explosive device 8, Pressure gauge 9, atmospheric valve 10, acoustic filter 11, air vent 12; The transfusion unit of forming by the active interface 15 on two low-temperature solenoid valves 13, two rustless steel liquid nitrogen carrier pipes 14, the end; The slender type cryoprobe unit of forming by a plurality of cryoprobes 16, air vent 17 and changeover plug 27; The cold needle tip thawing unit of forming by two microminiature high-pressure nitrogen bottles 18, decompressor 19, electromagnetic valve 20, nitrogen heat exchanger 21, intelligent digital temperature controller 22 and two electromagnetic valves 23 of air inlet of communicating with infusion tube top bypass duct side; By being installed in thermocouple 24 in the cryoprobe tip, being attached thereto two intelligent low-temperatures that connect digital temperature controller 25, many root tissues thermometric needle 26, changeover plugs 27, being attached thereto the intelligent temperature control unit that Elapsed Time Code Generator 29 that the digital display instrument 28 of two low temperature that connect and cooling freeze time-delay is formed; The apparent control unit of forming by external colored B ultrasonic 30 and computer 31; Install Numeral operation display screen Unit 32 of together forming concentratedly by all intelligence instrument displays temperatures and the charactron of time, color touch formula operation push-button.
Operation principle of the present utility model is:
1. filling liquid nitrogen: with external low-temperature (low temperature) vessel liquid supplementation pipe with after feed liquor valve 3 interfaces link to each other, close atmospheric valve 10, open feed liquor valve 3, liquid nitrogen promptly is pressed in supercharging discharge opeing Dewar flask 1, digital liquid level meter 5 display digits, stop filling when arriving the regulation value, close feed liquor valve 3, shed external liquid supplementation pipe, the filling liquid nitrogen finishes.
2.B overdetermination position puncture cryoprobe: open colored B ultrasonic 30 and computer 31, pass through video image, after Ultrasonic-B probe detects the destination organization accurate location, the 16 difference percutaneous punctures of 2-8 cryoprobe to destination organization, are inserted into many root tissues thermometric needle 26 also puncture appropriate location, destination organization edge simultaneously.
3. the cryosurgery technical parameter is set: root a tree name clinical experience and needs,, thawing temperature 32 freezing by the Numeral operation display screen and freezing time-delay button are set the cryogenic temperature value at pre-set cryoprobe tip respectively and (generally are set in the time value (3-8 minute) of-196 ℃ and freezing time-delay.Cooling time length, can finally reach-50 ℃ with the destination organization edge is foundation.
4. prepare before freezing: at first open the pressure charging valve 6 on supercharging discharge opeing Dewar type container 1, observe Pressure gauge 9, regulate adjust blood pressure regulator 7, gauge hand is pointed between the 2.0-2.5MPa.Open microminiature high pressure nitrogen steel cylinder 18 air outlet valves then, regulate decompressor 19 outlet pressure is decompressed between the 0.6-0.8MPa.
5. freezing: as to start Numeral operation display screen 32 freezing buttons, low-temperature solenoid valve 13 is opened, liquid nitrogen in the Dewar type container 1 under pressure, promptly flow into the tip of infusion tube 14 and cryoprobe 16 by low-temperature solenoid valve 13 from center outlet tube 2, after carrying out heat exchange intensely with the tip, the most advanced and sophisticated fast-refrigerating cooling of cryoprobe.Gas nitrogen after the heat exchange is from air vent emptying.The situation of cold needle tip variations in temperature is by the digital temperature controller 25 of most advanced and sophisticated thermocouple 24 and the intelligent low-temperature that links to each other, show by Numeral operation display screen 32 corresponding digital green pipes, destination organization lip temperature and variation also by the thermocouple 26 at thermometric needle tip and the digital display instrument 27 of low temperature that links to each other, are shown by Numeral operation display screen 32 corresponding digital green pipes.Simultaneously in computer 31, show fluid activity and each one time of the cryoprobe temperature graph of a relation picture that each cryoprobe 16 liquid nitrogen stream is threaded a pipe by image switching.The digital temperature controller 25 of intelligent low-temperature by to the driving of low-temperature solenoid valve 13 with close, can guarantee the cryoprobe tip temperature, in predetermined cooling time, maintain in the cryogenic temperature value of being scheduled to (error<5%=) relatively.
6. the most advanced and sophisticated thawing of cryoprobe: after arriving at predetermined cooling time, low-temperature solenoid valve 13 outages start the most advanced and sophisticated thawing button of Numeral operation display screen 32 cryoprobes, and electromagnetic valve 20 unlatchings, nitrogen heat exchanger 21, intelligent digital temperature controller 22 are devoted oneself to work.When corresponding nitrogen temperature digital green pipe on the operating display 32 shows to more than 150 ℃ the time, intelligent digital temperature controller 22 promptly drives electromagnetic valve 13, hot nitrogen is poured cryoprobe 16 most advanced and sophisticated heating through infusion tube 14, nitrogen temperature digital green pipe temperature displayed on the Numeral operation display screen 32 is in fast rise, when temperature reaches more than 0 ℃, 21 outages of electromagnetic valve 20 nitrogen electric heaters quit work, this moment, the patient can extract cryoprobe out from destination organization, and it is freezing to finish the first round.In case of necessity, can be from the active interface on the infusion tube 14 15, fast quick-detach and be connected that other 2-6 is individual to insert cryoprobe 16 in the destination organization in advance repeats second and takes turns or third round, four-wheel frozen-thaw process, thoroughly freezes cancerous cell in the prang tissue with this.
7. finish operation:: behind the cryosurgery of finishing destination organization, can extract the cryoprobe 16 in destination organization out and organize thermometric needle 26, close pressure charging valve 6 then, open atmospheric valve 10, behind the nitrogen in the Dewar type container 1 of releasing, finish operation.

Claims (9)

1. the interior low-temperature tumor therapy apparatus of B ultrasonic location multi-cold-needle puncture body is characterized in that this hypothermia therapy unit comprises storage liquid unit, transfusion unit, slender type cryoprobe unit, cold needle tip thawing unit, intelligent temperature control unit, shows control unit and Numeral operation display screen unit; Wherein storing the liquid unit comprises from supercharging discharge opeing Dewar type container (1), slender type cryoprobe unit comprises a plurality of cryoprobes (16), air vent (17) and thermocouple changeover plug (27), transfusion unit comprises low-temperature solenoid valve (13), liquid nitrogen carrier pipe (14) and probe active interface (15), cold needle tip thawing unit comprises microminiature high-pressure nitrogen bottle (18), decompressor (19), electromagnetic valve (20), nitrogen heat exchanger (21), the intelligent temperature control unit comprises the thermocouple (24) that is installed in the cryoprobe tip, the digital temperature controller (25) of the intelligent low-temperature that links to each other with thermocouple (24), lesion tissue thermometric needle (26), show the control unit and comprise B ultrasonic (30) and computer (31), the Numeral operation display screen unit comprises display screen (32); Center discharge pipe (2) in supercharging discharge opeing Dewar type container (1) is connected with liquid nitrogen carrier pipe (14) by low-temperature solenoid valve (13), the end of liquid nitrogen carrier pipe (14) connects probe active interface (15), cryoprobe (16) is connected on the probe active interface (15), after microminiature high-pressure nitrogen bottle (18) passed through decompressor (19), electromagnetic valve (20), nitrogen heat exchanger (21), the air inlet electromagnetic valve (23) that communicates with the top bypass duct side of liquid nitrogen carrier pipe (14) was connected.
2. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location is characterized in that storing the liquid unit and also comprises pressure charging valve (6), adjust blood pressure regulator (7), safety anti-explosive device (8), Pressure gauge (9), atmospheric valve (10), acoustic filter (11) and the air vent (12) that is connected successively with Dewar type container (1).
3. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location, it is characterized in that storing the liquid unit and also comprise feed liquor valve (3), capacitance sensor (4) and digital liquidometer (5), digital liquidometer (5) is connected with capacitance sensor (4).
4. B ultrasonic according to claim 1 location spininess puncture low-temperature tumor therapy apparatus is characterized in that the liquid nitrogen carrier pipe (14) in the transfusion unit has two, and every is the inside and outside fine vacuum multilayer insulation liquid nitrogen carrier pipe that is made of metal hose.
5. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location is characterized in that cryoprobe made by three elongated thin-wall stainless steel intussusceptions, has good vacuum heat-insulation characteristic, and the plurality of specifications size is arranged.
6. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location is characterized in that twin-channel liquid nitrogen carrier pipe (14), active interface (15) and a plurality of cryoprobe (16) in the transfusion unit is communicated with and cold needle tip thawing unit formation hot nitrogen channel loop.
7. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location is characterized in that cold needle tip thawing unit also comprises intelligent digital temperature controller (22).
8. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location, it is characterized in that the intelligent temperature control unit also comprises the digital display instrument (28) of low temperature, the digital display instrument of this low temperature (28) is connected with many root tissues of focus thermometric needle (26) by changeover plug (27).
9. low-temperature tumor therapy apparatus in the multi-cold-needle puncture body of B ultrasonic according to claim 1 location is characterized in that the intelligent temperature control unit comprises that also cooling freezes the Elapsed Time Code Generator of time-delay (29).
CN 02220581 2002-05-16 2002-05-16 B-ultrasonic location multi-cold-needle puncture internal tumor cryotherapy apparatus Expired - Fee Related CN2544689Y (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101396299B (en) * 2008-11-12 2010-11-10 郁如煌 Dewar integrated low-temperature operation device coupled with celioscope
CN101606862B (en) * 2009-07-14 2011-04-06 郁如煌 Simple low-temperature operation device for treating in-vivo tumour under aid of ultrasonic or celioscope
CN101330880B (en) * 2005-12-16 2011-04-20 爱尔伯电子医疗设备公司 Cryosurgical device with a probe coupling formed from the socket and the plug of cryoprobes
CN101797179B (en) * 2010-01-15 2011-07-20 浙江大学 Low-temperature therapeutic equipment using coolant
CN102784004A (en) * 2012-02-23 2012-11-21 中国人民解放军第三军医大学第一附属医院 Liquid nitrogen minimally-invasive cold knife
CN102935010A (en) * 2012-11-21 2013-02-20 湖南爱芷生医疗科技有限公司 Deep hypothermia therapy apparatus for rectal cancer
CN104548324A (en) * 2015-01-13 2015-04-29 刘素娟 Refrigeration medicine dual-purpose intervention therapeutic apparatus for medical oncology
CN109907815A (en) * 2018-12-10 2019-06-21 康沣生物科技(上海)有限公司 A kind of pressurization Cryoablation system certainly

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101330880B (en) * 2005-12-16 2011-04-20 爱尔伯电子医疗设备公司 Cryosurgical device with a probe coupling formed from the socket and the plug of cryoprobes
CN101396299B (en) * 2008-11-12 2010-11-10 郁如煌 Dewar integrated low-temperature operation device coupled with celioscope
CN101606862B (en) * 2009-07-14 2011-04-06 郁如煌 Simple low-temperature operation device for treating in-vivo tumour under aid of ultrasonic or celioscope
CN101797179B (en) * 2010-01-15 2011-07-20 浙江大学 Low-temperature therapeutic equipment using coolant
CN102784004A (en) * 2012-02-23 2012-11-21 中国人民解放军第三军医大学第一附属医院 Liquid nitrogen minimally-invasive cold knife
CN102935010A (en) * 2012-11-21 2013-02-20 湖南爱芷生医疗科技有限公司 Deep hypothermia therapy apparatus for rectal cancer
CN104548324A (en) * 2015-01-13 2015-04-29 刘素娟 Refrigeration medicine dual-purpose intervention therapeutic apparatus for medical oncology
CN109907815A (en) * 2018-12-10 2019-06-21 康沣生物科技(上海)有限公司 A kind of pressurization Cryoablation system certainly
CN109907815B (en) * 2018-12-10 2023-11-03 康沣生物科技(上海)股份有限公司 Self-pressurizing cryoablation system

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