CN113907864A

CN113907864A - Multifunctional liquid nitrogen freezing therapeutic device

Info

Publication number: CN113907864A
Application number: CN202010665202.3A
Authority: CN
Inventors: 张湘民; 张依秋; 禹恩佳
Original assignee: Guangzhou Pairuomi Medical Devices Co ltd
Current assignee: Guangzhou Pairuomi Medical Devices Co ltd
Priority date: 2020-07-10
Filing date: 2020-07-10
Publication date: 2022-01-11

Abstract

The utility model provides a multi-functional liquid nitrogen cryotherapy ware, includes freezing head, freezing pole, liquid nitrogen pipe, liquid nitrogen container, sealed lid and controller, its characterized in that: 1. the freezing head is made of metal material with good heat conduction to form a structure with one closed end and one open end and a gasification chamber, a liquid nitrogen enhanced gasification heat conduction device is arranged in the freezing head and consists of metal wires or metal nets with good heat conduction, one end of the freezing head is welded and fixed on the metal wall of the closed treatment end of the gasification chamber of the freezing head, and the other end of the freezing head is dissociated and is opposite to a nozzle of a liquid nitrogen pipe in the freezing rod; 2. the freezing rod consists of three layers of sleeves, the innermost layer of sleeve is a liquid nitrogen pipe, a nitrogen gas discharge pipe is arranged between the middle layer of sleeve and the inner layer of sleeve, and a cold insulation layer is arranged between the middle layer of sleeve and the outer layer of sleeve, and the cold insulation layer can be arranged into a vacuum cavity structure or a heating nitrogen flow structure or an electric heating element constant temperature structure. 3. The controller part adopts self-heat-transfer pressurization and electric heating pressurization modes and is provided with a manual trigger. Simple structure, low cost, convenient operation, good effect and convenient popularization and application.

Description

Multifunctional liquid nitrogen freezing therapeutic device

Technical Field

The present invention belongs to a medical appliance, particularly to a medical appliance for liquid nitrogen low-temperature freezing treatment.

Background

Cryotherapy or cryosurgery is widely used in various clinical departments, such as dermatology, obstetrics and gynecology, stomatology, ophthalmology, otorhinolaryngology, oncology, and the like, and can be used for treating various superficial neoplasms, hemangiomas and certain benign and malignant tumors. It is used in otorhinolaryngology for treating lymphoid follicle hyperplasia of chronic rhinitis, epistaxis, chronic tonsillitis, chronic pharyngitis, and various neoplasms of nasopharynx and larynx. Because the anatomical parts of the ear, nose and throat are deeper and narrower, the freezing therapeutic apparatus is specially requiredIn order to solve the problem, the conventional cryotherapy device and the cryohead are difficult to enter the sinus cavity pipeline with nasopharynx and larynx stenosis for cryotherapy. The existing cryotherapy apparatus has various specifications, a small handheld liquid nitrogen cryotherapy device and a larger throttling cryoknife with a high-pressure gas container. The main disadvantages are: 1. the small liquid nitrogen cryotherapy device is low in freezing speed, the cryotherapy device can be sprayed with liquid nitrogen only by shaking, a liquid nitrogen pipe nozzle is large, the sprayed liquid nitrogen is thick and thick, and is difficult to attach to a treatment target spot and splashes to a non-treatment part, so that the treatment target spot is inaccurate, and the non-treatment target spot is damaged by side. 2. Liquid nitrogen in the contact type freezing head is not gasified enough, and the liquid nitrogen which is not gasified sufficiently is sprayed out from the air outlet when the injection pressure is higher, so that the freezing effect of the freezing head is reduced, the freezing rod is excessively frozen, normal tissues are easily damaged, and a liquid nitrogen conveying pipeline is easily blocked by ice slag. 3. The large-scale cryotherapy device has complex structure and high price, and various freezing heads suitable for ear, nose and throat are also lacked. When the medical freezing therapeutic apparatus is used for treating the focus deep in the uterine tissue of a human body, the non-treatment part of the freezing head of the medical freezing therapeutic apparatus needs to have good cold insulation performance so as to avoid freezing injury to the normal tissue. The more effective cold insulation method of the prior cryotherapy device is generally regarded as vacuum cavity cold insulation method, namely, a sealed vacuum cavity is formed on the periphery of the non-treatment part of the cryotherapy head. To achieve good cold insulation, the vacuum chamber needs to be large, and the vacuum degree needs to be kept at 10^-4Above mm Hg. The freezing head has complex technology and high manufacturing cost, and is difficult to be made thin and easy to be damaged. Some cryotherapeutic devices also use electrical heating materials and thermal insulation materials for cold insulation. But because of its large size, it is currently only suitable for cryotherapy of superficial parts and well exposed body cavities. In order to improve the refrigeration effect of the freezing head and the cold insulation effect of the non-treatment part of the freezing rod of the freezing head, the liquid nitrogen cryotherapy device in the body of the Chinese utility model patent (application number: CN 87204852) discloses the technical proposal that a hot air cold insulation cavity is arranged at the periphery of the non-treatment part of the freezing head, the hot air cold insulation cavity is communicated with an exhaust pipe at the position close to the treatment end of the freezing head, the other end is communicated with an electric heating pipe, and the inlets of the electric heating pipe are respectively communicated with a liquid nitrogen containerThe nitrogen conveying pipe and a nitrogen shunt pipe from the nitrogen separator. Chinese patent application No. CN201480078316 discloses a cryogen phase separation technique in cryosurgical instruments. A cryogen delivery tube spirals in fluid-tight contact with the inner surface of the shaft to form a spiraled cryogen evacuation pathway that extends from the distal end of the shaft along a portion of the length of the cryosurgical instrument. The cryogen delivery tube uses centrifugal force to force the two-phase flow of cryogen through phase separation and to drive the liquid phase toward the outer wall of the helical coil and the outer surface of the helical gap, with heat exchange occurring near the outer wall of the instrument. Chinese patent publication No. CN102378600 discloses a cryosurgical instrument with enhanced heat transfer, a cryosurgical instrument and method utilizing improved heat transfer characteristics. The cryosurgical device comprises: a tubular housing; a coolant supply passage; a heat exchange enhancing member located in the housing, arranged along a longitudinal axis of the housing; an annular cooling channel between the heat exchange enhancing member and the tubular housing; a tip cooling and cryogen flow directing section to conduct the temperature of the cryogen flow to the tip; and an insulating member located in the tubular housing. Chinese utility model patent (application number CN 201821181634) tumor cold and hot compound probe and tumor cold and hot compound treatment device, probe body is close to syringe needle portion and is equipped with the heat exchange district section, and the heat exchange district section has interior finned tube structure, and interior finned tube structure has a plurality of interior finned tubes, and a plurality of interior finned tubes set up along probe body outer wall circumference. Chinese and US patents (application nos. CN201180022782, US 7938822) employ heating and cooling of cryosurgical instruments with a single cryogen. Cryosurgical systems are characterized by cooling and heating with a single type of cryogen, but from two different sources. The liquid cryogen cools the tip of a cryosurgical instrument within a cryosurgical system, such as a cryoprobe or cryocatheter. The gaseous cryogen is further heated by a heating element, preferably an electrical heating element, to supply the heat required for the thawing and release portions of the cryosurgical procedure. The above technical solutions are numerous, but still have defects and need to be improved. In order to solve the problems of clinical application of the cryotherapy devices, the freezing head is further improvedThe refrigerating effect of the invention and the cold insulation effect of the non-treatment part of the freezing rod of the freezing head meet the clinical use requirement as much as possible, and particularly, various freezing heads suitable for the department of otorhinolaryngology are designed.

Disclosure of Invention

The utility model provides a multi-functional liquid nitrogen cryotherapy ware, includes freezing head, freezing pole, liquid nitrogen pipe, liquid nitrogen container, sealed lid and controller, its characterized in that: 1. the freezing head is made of metal material with good heat conduction to form a structure with one closed end and one open end and a gasification chamber, a liquid nitrogen enhanced gasification heat conduction device is arranged in the freezing head and consists of metal wires or metal nets with good heat conduction, one end of the freezing head is welded and fixed on the metal wall of the closed treatment end of the gasification chamber of the freezing head, and the other end of the freezing head is dissociated and is opposite to a nozzle of a liquid nitrogen pipe in the freezing rod; 2. the freezing rod consists of three layers of sleeves, wherein the innermost sleeve is a liquid nitrogen pipe, a nitrogen gas discharge pipe is arranged between the middle sleeve and the inner sleeve, and a cold insulation layer is arranged between the middle sleeve and the outer sleeve, and the cold insulation layer can be arranged into a vacuum cavity structure or a heating nitrogen flow structure or an electric heating element constant temperature structure; 3. the controller part adopts a self-heat-transfer pressurization and electric heating pressurization mode and is provided with a manual trigger, the manual trigger is connected with a valve of a gas exhaust hole of a liquid nitrogen container sealing cover or a valve of a freezing rod nitrogen gas discharge pipe outlet and is provided with a return spring; 4. the junction of liquid nitrogen pipe and liquid nitrogen container liquid nitrogen conveyer pipe is equipped with liquid nitrogen and nitrogen gas separator, liquid nitrogen and nitrogen gas separator's import and liquid nitrogen container liquid nitrogen conveyer pipe connection, and the export divide into liquid nitrogen export and nitrogen gas export, and the liquid nitrogen export is connected with the liquid nitrogen union coupling in the freezing pole, and the nitrogen gas export passes through electric heating element constant temperature structure and is connected and by first manual control governing valve control nitrogen flow with the cold layer that separates in the freezing pole.

The freezing head is made of stainless steel or silver-copper alloy, a gasification chamber and a liquid nitrogen enhanced heat conduction gasification device are arranged in the freezing head, the appearance of a treatment end of the contact tissue is designed into a contact type freezing head with various shapes such as a spherical shape, a hemispherical shape, a conical shape, a flat shape, a bent hook shape, a slender shape and the like according to the requirement of a treatment part, the freezing head is fixedly or detachably connected with an outer sleeve of a freezing rod in a welding way, and is fixedly or detachably connected with a sealing cover of a liquid nitrogen container and a controller, thermocouple temperature sensing elements are respectively arranged in the freezing head and the freezing rod and are connected with a temperature display controller to respectively display the real-time temperature change of the freezing head and the freezing rod, and a temperature alarm and a timer are arranged. The freezing head is designed into a liquid nitrogen freezing nozzle and is composed of a liquid nitrogen pipe in a freezing rod, the liquid nitrogen pipe is made of thin-wall stainless steel with the diameter of 1.5-3 mm, a liquid nitrogen nozzle at the front end of the liquid nitrogen pipe is slightly reduced, a cold insulation protective sleeve is sleeved outside the liquid nitrogen pipe, the front end of the protective sleeve is reduced, the nozzle can be bent at an angle of 0-90 degrees, and the cold insulation protective sleeve is made of nontoxic medical plastic or silica gel and can be cleaned, sterilized and reused or used at one time. The liquid nitrogen enhanced heat conduction gasification device matched with the freezing head is composed of metal wires or metal nets made of copper or silver alloy materials, the metal wires or the metal nets are in a short brush shape, one end of the metal wires or the metal nets is welded and fixed on the metal wall of the treatment end of the freezing head gasification chamber, the other end of the metal wires or the metal nets is free and is close to a nozzle of a liquid nitrogen pipe in the freezing rod correspondingly, the front end of the freezing head is closed, and the rear end of the freezing head is open and connected with the freezing rod and is communicated with the nozzle of the liquid nitrogen pipe in the freezing rod and a nitrogen discharge pipe. The cold insulation layer of the freezing rod is positioned outside the nitrogen gas discharge pipe and is made of a resistance heating wire or an electric heating film with an insulating layer, the power supply voltage is 5-12V direct current, the power is 15-50W, a thermocouple temperature sensing element is arranged for monitoring the temperature of the cold insulation layer of the freezing rod, a constant temperature and thermal protection device is arranged, the temperature of the cold insulation layer is set to be constant at 25-35 ℃, and the thermal protection temperature is 40 ℃. Another embodiment is: the utility model discloses a freezing pole, including freezing pole, nitrogen gas discharge pipe, rear end, nitrogen gas adjusting valve, nitrogen gas pipe, the cold insulation layer of freezing pole is located outside the nitrogen gas discharge pipe, for the intermediate layer space between freezing pole middle level sleeve pipe and the outer sleeve pipe, front end and nitrogen gas discharge pipe entry intercommunication, the rear end is in the sealed lid department of nearly liquid nitrogen container through intercommunication in a nitrogen gas adjusting valve and the nitrogen gas pipe and the liquid nitrogen container, at freezing pole outer sleeve pipe, nitrogen gas adjusting valve and nitrogen gas pipe are equipped with the resistance heating wire of taking the insulating layer, supply voltage is 5 to 12 volts for direct current, power 15 to 50 watts, be equipped with the cold insulation layer temperature of thermocouple temperature sensing element control freezing pole, and be furnished with constant temperature and thermal protection device, set for cold insulation layer temperature invariant 25 to 35 degrees centigrade, thermal protection temperature is 40 degrees centigrade. The controller is provided with a manual trigger, the upper end of the manual trigger is connected with a sealing cover on the liquid nitrogen container through a movable joint, a hemispherical sealing plug is arranged at the position close to the movable joint and corresponds to an exhaust hole of the sealing cover on the liquid nitrogen container to be in an open state or corresponds to a valve at the outlet of a nitrogen gas discharge pipe of the freezing rod to be in a closed state, the lower end of the manual trigger is free, a reset spring and an electric heating circuit switch are arranged, when the lower end of the manual trigger is pressed, the exhaust hole of the sealing cover is sealed by the hemispherical sealing plug, the circuit switch is switched on when the pressing force is increased, and the resistance heating wire of the cold insulation layer of the freezing rod and the resistance heating wire in the liquid nitrogen container are heated in an electrified mode. A liquid nitrogen pipe in the freezing rod penetrates through the liquid nitrogen container sealing cover through a liquid nitrogen conveying pipe to reach the inside of the liquid nitrogen container, a heat transfer sleeve is arranged outside the liquid nitrogen conveying pipe and is provided with a resistance heating wire, and the bottom end of the liquid nitrogen conveying pipe is close to the bottom of the liquid nitrogen container and is provided with a filter screen. The power supply voltage of the resistance heating wire is 5 to 12 volts of direct current, the power is 15 to 50 watts, and a heat transfer sleeve outside the liquid nitrogen conveying pipe penetrates through the sealing cover of the liquid nitrogen container to be fixed and is connected with a heat absorber. The heat absorber is made of metal material with good heat conduction, is in a hollow box shape, is welded with a heat transfer sleeve outside the liquid nitrogen conveying pipe, and is provided with a temperature display screen on the upper side, a power socket on the lower part and a nitrogen adjusting valve knob on the side.

The liquid nitrogen container is a Dewar flask structure container with a vacuum heat insulation layer, the capacity of the liquid nitrogen container is 0.5-30 liters, the liquid nitrogen container is provided with a sealing cover, an electric heating supercharging device, a pressure controller, a manometer and a pressure regulating safety valve, a liquid nitrogen conveying pipe and a nitrogen pipe penetrate through the sealing cover to reach the liquid nitrogen container, the liquid nitrogen pipe is conveyed and extended to be of a hose structure with the electric heating or vacuum heat insulation layer, the other end of the liquid nitrogen pipe is connected with a liquid nitrogen and nitrogen separation device in a handheld liquid nitrogen freezing therapeutic apparatus, and the nitrogen pipe is extended to be connected with a cold insulation layer in a freezing rod through an electric heating element constant temperature structure and the flow of nitrogen is controlled by a second manual control regulating valve.

Drawings

Fig. 1 is a schematic structural diagram of a handheld cryotherapeutic device according to an embodiment of the present invention.

FIG. 2 is a schematic diagram of the detailed structure of the handheld cryotherapeutic device according to an embodiment of the present invention.

Fig. 3 is an enlarged schematic view of the freezing head and freezing rod of the present invention.

Fig. 4 is an enlarged schematic view of another embodiment of the freezing head and freezing bar of the present invention.

Figure 5 is a schematic diagram of the fine structure of various freezer heads and freezer rods of the present invention.

Fig. 6 is a schematic structural view of a nasal turbinate freezing head and freezing rod of the present invention.

Fig. 7 is a schematic view of the tongue root freezing head and freezing bar of the present invention.

Fig. 8 is a schematic structural view of a freezing spray gun of a hand-held freezing therapeutic device according to the present invention.

Fig. 9 is a schematic structural view of a cryogun of a split cryotherapeutic device according to the present invention.

Fig. 10 is a fine structure diagram of a split type cryotherapy device cryogun of the invention.

Fig. 11 is a schematic structural diagram of a split-type cryotherapeutic device cryogun and a main machine according to the present invention.

Fig. 12 is a schematic structural view of a flexible freezing head and a main machine of another split-type cryotherapeutic apparatus of the present invention.

Detailed Description

The following detailed description of embodiments of the invention will be made with reference to the accompanying drawings.

Referring to fig. 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12, a multifunctional liquid nitrogen cryotherapy apparatus includes a freezing head 1, a freezing rod 5, a liquid nitrogen pipe 7, a liquid nitrogen container 28, a sealing cover 22 and a controller, wherein: 1. the freezing head 1 is made of metal material with good heat conduction to be a structure with one closed end and one open end and a gasification chamber, a liquid nitrogen enhanced gasification heat conduction device 3 is arranged in the freezing head and consists of metal wires or metal nets with good heat conduction, one end of the freezing head is welded and fixed on the metal wall of the treatment end with the closed gasification chamber of the freezing head, and the other end of the freezing head is dissociated and is opposite to a nozzle 4 of a liquid nitrogen pipe in a freezing rod; 2. the freezing rod 5 consists of three layers of sleeves, wherein the innermost sleeve 7-1 is a liquid nitrogen pipe 7, a nitrogen gas discharge pipe 8 is arranged between the middle sleeve 8-1 and the inner sleeve 7-1, a cold insulation layer 9 is arranged between the middle sleeve 8-1 and the outer sleeve 9-1, and the cold insulation layer 9 can be arranged into a vacuum cavity structure or a heating nitrogen flow structure or an electric heating element constant temperature structure; 3. the controller part adopts a self-heat-transfer pressurization and electric heating pressurization mode, is provided with a manual trigger 12, the manual trigger 12 is connected with a liquid nitrogen container 28, a sealing cover 22, an exhaust hole 19 or a valve 15 of a freezing rod nitrogen gas discharge pipe outlet 11, and is provided with a return spring 13; 4. the connection part of the liquid nitrogen pipe 7 and the liquid nitrogen delivery pipe 32 of the liquid nitrogen container 28 is provided with a liquid nitrogen and nitrogen separation device 30, the liquid nitrogen and nitrogen separation device 30 is a cylindrical sealed container, a liquid nitrogen inlet is arranged below the liquid nitrogen and is connected with the liquid nitrogen delivery pipe 32 of the liquid nitrogen container 28, and the liquid nitrogen inlet extends to the middle part of the inner side of the liquid nitrogen and nitrogen separation device 30 through a thin metal pipe. Two outlets are arranged above the liquid nitrogen and nitrogen separation device 30 and respectively are a liquid nitrogen outlet and a nitrogen outlet, the liquid nitrogen outlet is connected with a liquid nitrogen pipe 7 in the freezing rod 5, the liquid nitrogen outlet extends to the bottom of the inner side of the liquid nitrogen and nitrogen separation device 30 through a thin metal pipe, the nitrogen outlet is connected with a cold insulation layer 9-1 in the freezing rod 5 through an electric heating element constant temperature structure 10, and the flow of nitrogen is controlled by a first manual control adjusting valve 16. The working principle of the liquid nitrogen and nitrogen gas separation device 30 is as follows: when liquid nitrogen flows into the liquid nitrogen and nitrogen separation device 30, the liquid nitrogen extends to the middle part of the inner side of the liquid nitrogen and nitrogen separation device 30 through the liquid nitrogen inlet metal thin pipe and flows out, the liquid nitrogen is separated from the nitrogen, the liquid nitrogen sinks to the bottom, and the liquid nitrogen extends to the metal thin pipe at the bottom through the liquid nitrogen outlet and flows into the liquid nitrogen pipe in the freezing rod. The nitrogen gas upwards passes through the nitrogen gas outlet and is communicated with a cold insulation layer 9-1 in the freezing rod 5 through an electric heating element constant temperature structure 10.

The freezing head 1 is made of stainless steel or silver-copper alloy, a gasification chamber and a liquid nitrogen enhanced heat conduction gasification device 2 are arranged in the freezing head, the appearance of a treatment end of a contact tissue is designed into a contact type freezing head with various shapes such as a spherical shape, a hemispherical shape, a conical shape, a flat shape, a hook shape, a slender shape and the like according to the requirement of a treatment part, the freezing head 1 is fixedly welded or detachably connected with an outer sleeve 9 of a freezing rod 5, the outer sleeve 9 of the freezing rod 5 is made of a thin metal pipe, the outer sleeve 9 of the freezing rod 5 is fixedly or detachably connected with a sealing cover 22, a sealing ring 21 and a controller of a liquid nitrogen container 28, and an outermost sleeve made of a material with good heat insulation performance can be added outside the outer sleeve of the freezing rod. Thermocouple temperature sensing elements 3 are respectively arranged in the freezing head 1 and the freezing rod 5, are connected with a temperature display controller 17, respectively display real-time temperature changes of the freezing head 1 and the freezing rod 5, and are provided with a temperature alarm and a timer. The thermocouple temperature sensing element 3, the temperature display controller 17, the temperature alarm and the timer are well known and commercially available products.

The other embodiment is that the freezing head 1 is designed into a liquid nitrogen freezing nozzle 4 and consists of a liquid nitrogen pipe 7 in a freezing rod 5, the liquid nitrogen pipe 7 is made of thin-wall stainless steel with the diameter of 1.5 to 3 mm, the liquid nitrogen nozzle 4 at the front end of the liquid nitrogen pipe is slightly reduced, a cold insulation protective sleeve is sleeved outside the liquid nitrogen pipe, the front end of the protective sleeve is reduced, the nozzle can be bent at an angle of 0 to 90 degrees, and the cold insulation protective sleeve is made of nontoxic medical plastic or silica gel and can be cleaned, sterilized and reused or used for one time.

The liquid nitrogen enhanced heat conduction gasification device 2 arranged in the freezing head 1 is composed of metal wires or metal nets made of copper or silver alloy materials, is in a short brush shape, the diameter of each metal wire is 0.05-0 mm and 5mm, one end of each metal wire is welded and fixed on the metal wall of the treatment end of the gasification chamber of the freezing head 1, and the other end of each metal wire is free and close to a liquid nitrogen pipe nozzle 4 of a liquid nitrogen pipe 7 in the freezing rod 5 correspondingly. The front end of the freezing head 1 is closed, and the rear end is open and is connected with an outer sleeve 9 of the freezing rod 5 and is communicated with a liquid nitrogen pipe nozzle 4 and a nitrogen gas discharge pipe 8 in the freezing rod 5. When liquid nitrogen is sprayed out of a nozzle of the liquid nitrogen pipe to the short brush-shaped metal wire of the liquid nitrogen enhanced heat conduction gasification device 2, the heat exchange gasification is rapid due to large contact area. When the temperature of the gasification chamber of the freezing head 1 is reduced, liquid nitrogen is more easily adhered to the metal wall of the gasification chamber and the short hairbrush-shaped metal wires, and the heat conduction freezing effect is further enhanced. The gasified nitrogen is discharged through a nitrogen discharge pipe 8.

The cold insulation layer 9 of the freezing rod 5 is positioned outside the nitrogen gas discharge pipe 8 and is made of a resistance heating wire or an electric heating film with an insulating layer, the power supply voltage is 5-12V direct current, the power is 15-50W, a thermocouple temperature sensing element is arranged to monitor the temperature of the cold insulation layer of the freezing rod, a constant temperature and thermal protection device 18 is arranged, the temperature of the cold insulation layer is set to be constant at 25-35 ℃, and the thermal protection temperature is 40 ℃. The existing resistance heating wire or electric heating film can be made thin, so that the diameter of the freezing rod can be made thin.

The other embodiment is that the cold insulation layer 9 of the freezing rod 5 is positioned outside the nitrogen gas discharge pipe 8 and is an interlayer space between the middle layer sleeve 8-1 and the outer layer sleeve 9-1 of the freezing rod, the front end of the cold insulation layer is communicated with the inlet of the nitrogen gas discharge pipe 8, the rear end of the cold insulation layer is communicated with the inside of the liquid nitrogen container 28 through a nitrogen gas adjusting valve 16 and a nitrogen gas pipe at the position close to the sealing cover 22 of the liquid nitrogen container, the outer sleeve 9-1, the nitrogen gas adjusting valve 16 and the nitrogen gas pipe of the freezing rod 5 are provided with resistance heating wires 10 with insulating layers, the power supply voltage is direct current 5-12V, the power is 15-50W, a thermocouple temperature sensing element is arranged to monitor the temperature of the cold insulation layer 9 of the freezing rod 5, and a constant temperature and thermal protection device 18 is arranged, the temperature of the cold insulation layer 9 is set to be constant at 25-35 ℃, and the thermal protection temperature is set to be 40 ℃. The method for isolating cold by hot air flow is simple in structure, and the freezing head and the freezing rod can be made smaller and are convenient to replace.

The controller is provided with a manual trigger 12, the upper end of the manual trigger 12 is connected with a sealing cover 22 on a liquid nitrogen container through a movable joint, a hemispherical sealing plug 15 is arranged at the position close to the movable joint, the upper end of the manual trigger is in an open state corresponding to an exhaust hole 19 of the sealing cover 22 on the liquid nitrogen container or in a closed state corresponding to a valve of an outlet 11 of a nitrogen gas discharge pipe of a freezing rod 5, the lower end of the manual trigger 12 is free, a reset spring 13 and an electric heating circuit switch 14 are arranged, when the lower end of the manual trigger 12 is pressed, the hemispherical sealing plug 15 seals the exhaust hole 18 of the sealing cover, the circuit switch 14 is switched on when the strength is increased, and the resistance heating wire 10 of the freezing rod cold insulation layer 9 and the resistance heating wire 23 in the liquid nitrogen container 28 are electrified and heated. The design scheme has the advantages of simple structure and easy operation, and can be conveniently controlled by one-hand operation.

The liquid nitrogen pipe 7 in the freezing rod 5 is extended to be a liquid nitrogen delivery pipe 32 which penetrates through a liquid nitrogen container sealing cover 22 to reach the inside of a liquid nitrogen container 28, a heat transfer sleeve 25 and a resistance heating wire 23 are arranged outside one section of the liquid nitrogen delivery pipe 32 in the liquid nitrogen container 28, the bottom end 26 of the liquid nitrogen delivery pipe 32 is close to the bottom of the liquid nitrogen container 28 and is provided with a filter screen 27, the power supply voltage of the resistance heating wire 23 is 5-12V direct current, the power is 15-50W, and the heat transfer sleeve 25 outside the liquid nitrogen container penetrates through the liquid nitrogen container sealing cover 22 to be fixed and is connected with a heat absorber 38. The heat absorber 38 is made of metal material with good heat conduction, is in a hollow box shape, is welded with the heat transfer sleeve 25 outside the liquid nitrogen pipe, and is provided with a temperature display screen 17 on the upper side, a power socket 20 on the lower part and a first manual control adjusting valve 16 on the side. The design scheme can avoid ice slag from blocking the liquid nitrogen conveying pipe and the liquid nitrogen nozzle. The heat absorber 38 can achieve self-pressurization effect by heat transfer, and has better effect by adding electric heating pressurization.

Referring to fig. 9, 10, 11 and 12, the liquid nitrogen container 28 is a dewar structure container with a vacuum heat insulation layer, the capacity of the liquid nitrogen container is 0.5 to 30 liters, the liquid nitrogen container is provided with a sealing cover 22, a second heat absorber 35, an electric heating pressure device 36, a pressure controller 37, a pressure gauge 34 and a pressure regulating safety valve 38, the sealing cover 22 is provided with a liquid nitrogen delivery pipe 32 and a nitrogen pipe 33 which penetrate into the liquid nitrogen container 28, the liquid nitrogen delivery pipe 32 is extended to be a hose structure with the electric heating or vacuum heat insulation layer, the other end of the liquid nitrogen delivery pipe is connected with a liquid nitrogen and nitrogen separation device 30 in the handheld liquid nitrogen freezing therapeutic device, the nitrogen pipe 33 is extended to be connected with a cold insulation layer 9 in the freezing rod 5 through an electric heating element constant temperature structure 10, and the nitrogen flow is controlled by a second manual control valve 29. The technical scheme of pre-pressurizing pressure storage and constant pressure is that the pressure in the liquid nitrogen container is set to be 0.02-0.08 MPa, preferably 0.05MPa, so that the freezing treatment efficiency can be improved, and the method is very safe and reliable. When the pressure is lower than the preset pressure value, the pressure controller 37 controls the electric heating pressurizing device 36 to be connected with the power supply, the resistance heating wire 23 of the heat transfer sleeve 25 is heated, and the liquid nitrogen in the liquid nitrogen container is gasified and pressurized. When the pressure reaches a preset pressure value, the pressure controller 37 controls the electric heating supercharging device 36 to turn off the power supply, and heating is stopped. The pressure regulating safety valve 40 can increase the safety factor of the liquid nitrogen container and the cryotherapeutic device. The technology of controlling the opening and closing of the valve of the outlet 11 of the nitrogen discharge pipe of the freezing rod 5 by adopting the manual trigger 12 is matched with the technical scheme of pre-pressurization pressure storage and constant pressure, so that the control of the freezing therapeutic device is more rapid and reliable. The liquid nitrogen conveying pipeline of the whole machine is smooth, a switch or a valve is not required to be arranged, and the fault rate is reduced. The second heat absorber 35 and the liquid nitrogen delivery pipe 32 are extended to be in an electrified heat hose structure, which is beneficial to the liquid nitrogen delivery to be in a two-phase delivery state, reduces the flow resistance of the liquid nitrogen, and can keep the liquid nitrogen delivery pipe 32 soft and not frozen.

When the device is used, proper liquid nitrogen is filled in a liquid nitrogen container, the sealing cover is covered, the action is slow, the sealing cover is screwed after a part of liquid nitrogen is gasified, and a liquid nitrogen conveying pipe is cooled. The patient is treated by placing the appropriate cryotip and cryorod, pressing the manual trigger 12, and observing the effect of the liquid nitrogen spray and the cryotip to confirm proper placement. If the spray freezing mode is adopted, the freezing head and the freezing rod are taken down, the cold insulation sleeve is directly sleeved on the spray pipe, the manual control trigger 12 is pressed to close the exhaust hole, the pressure in the liquid nitrogen container is increased, and the liquid nitrogen is sprayed out from the nozzle of the liquid nitrogen pipe. The liquid nitrogen is sprayed out to be suitable for being applied to the focus of the patient. If the protective film is used in the internal cavity of a patient, such as the oropharynx, the nasal cavity, the tongue root or other parts, the protective film needs to be protected from cold so as to avoid frostbite on normal tissues. The freezing head is selected to contact with the focus in a proper size, a freezing program is started, the temperature of the tissue contacted with the freezing head is seen to be reduced, ice forms ice balls, the ice balls reach the proper size, the continuous freezing is stopped, a second manual control adjusting valve 29 can be adjusted, and the nitrogen flow is controlled to be changed into a rewarming state. After freezing for one freeze-thaw cycle, a second freeze-thaw cycle and a third freeze-thaw cycle may be repeated to completely freeze-ablate the lesion. Different responses will occur after freezing, and the greater the extent of tissue freezing or repeated freezing, the more severe the response after treatment. The patient needs to be explained, the treatment of the frozen wound surface is well done, and the wound surface is periodically reviewed, so that the optimal effect is achieved, and the adverse reaction is reduced.

The invention has the beneficial effects that: 1. the freezing head is internally provided with a liquid nitrogen enhanced gasification heat conduction device which is composed of a metal wire or a metal net with good heat conduction, one end of the device is welded and fixed on the metal wall of the treatment end of the freezing head gasification chamber, the other end of the device is free and opposite to the nozzle of the liquid nitrogen pipe in the freezing rod, and the device can obviously enhance the gasification effect and the heat conduction effect of the liquid nitrogen and can quickly freeze the freezing head. The key technology of the quick freezing of the freezing head is to enlarge the contact area with liquid nitrogen and proper temperature difference. The contact area between the freezing head gasification chamber and the liquid nitrogen is small, the temperature difference is large, an air cushion is formed between the liquid nitrogen and the freezing head metal surface, and the heat exchange efficiency and the heat conduction efficiency are low. The liquid nitrogen gasification's reinforcing means is equipped with good wire and the metal mesh of heat conduction mainly, and its free end enlarges the area of contact with the liquid nitrogen, and the difference in temperature is suitable to be the adhesion state, can not form the air cushion, and the heat exchange is abundant, and the other end and the metal covering welding reinforcing heat-conduction of freezing head vaporizer make the freezing effect of gasification reinforcing. 2. The freezing rod cold insulation layer adopts a method of heating nitrogen flow at constant temperature for heat insulation, can reduce the volume and the diameter of the freezing rod, is safe and effective, and can select different freezing heads and freezing rods according to different treatment parts so as to be convenient for replacement and disinfection. 3. The handheld liquid nitrogen cryotherapy device has the advantages of simple overall structure, low manufacturing cost, convenient operation and convenient popularization and application. The split type liquid nitrogen freezing therapeutic device is suitable for being used in an operating table or complex cases, and particularly, a slender and flexible freezing therapeutic head is suitable for being used for a focus deep in a body. 4. By adopting the technical scheme of pre-pressurization and pressure storage and constant pressure, the freezing treatment efficiency can be improved, and the freezing treatment device is safe and reliable.

In view of the foregoing, it will be seen that various other embodiments of the invention may be devised without departing from the basic scope thereof, and it is therefore intended that all such changes and modifications as fall within the true spirit and scope of the appended claims be embraced by the present invention.

Claims

1. The utility model provides a multi-functional liquid nitrogen cryotherapy ware, includes freezing head, freezing pole, liquid nitrogen pipe, liquid nitrogen container, sealed lid and controller, its characterized in that: 1. the freezing head is made of metal material with good heat conduction to form a structure with one closed end and one open end and a gasification chamber, a liquid nitrogen enhanced gasification heat conduction device is arranged in the freezing head and consists of metal wires or metal nets with good heat conduction, one end of the freezing head is welded and fixed on the metal wall of the closed treatment end of the gasification chamber of the freezing head, and the other end of the freezing head is dissociated and is opposite to a nozzle of a liquid nitrogen pipe in the freezing rod; 2. the freezing rod consists of three layers of sleeves, wherein the innermost sleeve is a liquid nitrogen pipe, a nitrogen gas discharge pipe is arranged between the middle sleeve and the inner sleeve, and a cold insulation layer is arranged between the middle sleeve and the outer sleeve, and the cold insulation layer can be arranged into a vacuum cavity structure or a heating nitrogen flow structure or an electric heating element constant temperature structure; 3. the controller part adopts a self-heat-transfer pressurization and electric heating pressurization mode and is provided with a manual trigger, the manual trigger is connected with a valve of a gas exhaust hole of a liquid nitrogen container sealing cover or a valve of a freezing rod nitrogen gas discharge pipe outlet and is provided with a return spring; 4. the junction of liquid nitrogen pipe and liquid nitrogen container liquid nitrogen conveyer pipe is equipped with liquid nitrogen and nitrogen gas separator, and liquid nitrogen and nitrogen gas separator's import and liquid nitrogen container liquid nitrogen conveyer pipe are connected, and the export divide into liquid nitrogen export and nitrogen gas export, and the liquid nitrogen export is connected with the liquid nitrogen union coupling in the freezing pole, and the nitrogen gas export passes through electric heating element constant temperature structure and is connected and by manual control governing valve control nitrogen flow with the cold layer that separates in the freezing pole.

2. The multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1, wherein: the freezing head is made of stainless steel or silver-copper alloy, a gasification chamber and a liquid nitrogen enhanced heat conduction gasification device are arranged in the freezing head, the appearance of a treatment end of the contact tissue is designed into a contact type freezing head with various shapes such as a spherical shape, a hemispherical shape, a conical shape, a flat shape, a bent hook shape, a slender shape and the like according to the requirement of a treatment part, the freezing head is fixedly welded or detachably connected with an outer sleeve of a freezing rod, the outer sleeve of the freezing rod is fixedly or detachably connected with a sealing cover of a liquid nitrogen container and a controller, thermocouple temperature sensing elements are respectively arranged in the freezing head and the freezing rod and are connected with a temperature display controller to respectively display the real-time temperature changes of the freezing head and the freezing rod, and a temperature alarm and a timer are arranged.

3. The multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1, wherein: the freezing head is designed into a liquid nitrogen freezing nozzle and is composed of a liquid nitrogen pipe in a freezing rod, the liquid nitrogen pipe is made of thin-wall stainless steel with the diameter of 1.5-3 mm, a liquid nitrogen nozzle at the front end of the liquid nitrogen pipe is slightly reduced, a cold insulation protective sleeve is sleeved outside the liquid nitrogen pipe, the front end of the protective sleeve is reduced, the nozzle can be bent at an angle of 0-90 degrees, and the cold insulation protective sleeve is made of nontoxic medical plastic or silica gel and can be cleaned, sterilized and reused or used at one time.

4. A multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1 or 2, wherein: the liquid nitrogen enhanced heat conduction gasification device matched with the freezing head is composed of metal wires or metal nets made of copper or silver alloy materials, the metal wires or the metal nets are in a short brush shape, one end of the metal wires or the metal nets is welded and fixed on the metal wall of the treatment end of the freezing head gasification chamber, the other end of the metal wires or the metal nets is free and is close to a nozzle of a liquid nitrogen pipe in the freezing rod correspondingly, the front end of the freezing head is closed, and the rear end of the freezing head is open and connected with the freezing rod and is communicated with the nozzle of the liquid nitrogen pipe in the freezing rod and a nitrogen discharge pipe.

5. A multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1 or 2, wherein: the cold insulation layer of the freezing rod is positioned outside the nitrogen gas discharge pipe and is made of a resistance heating wire or an electric heating film with an insulating layer, the power supply voltage is 5-12V direct current, the power is 15-50W, a thermocouple temperature sensing element is arranged for monitoring the temperature of the cold insulation layer of the freezing rod, a constant temperature and thermal protection device is arranged, the temperature of the cold insulation layer is set to be constant at 25-35 ℃, and the thermal protection temperature is 40 ℃.

6. A multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1 or 2, wherein: the utility model discloses a freezing pole, including freezing pole, nitrogen gas discharge pipe, rear end, nitrogen gas adjusting valve, nitrogen gas pipe, the cold insulation layer of freezing pole is located outside the nitrogen gas discharge pipe, for the intermediate layer space between freezing pole middle level sleeve pipe and the outer sleeve pipe, front end and nitrogen gas discharge pipe entry intercommunication, the rear end is in the sealed lid department of nearly liquid nitrogen container through intercommunication in a nitrogen gas adjusting valve and the nitrogen gas pipe and the liquid nitrogen container, at freezing pole outer sleeve pipe, nitrogen gas adjusting valve and nitrogen gas pipe are equipped with the resistance heating wire of taking the insulating layer, supply voltage is 5 to 12 volts for direct current, power 15 to 50 watts, be equipped with the cold insulation layer temperature of thermocouple temperature sensing element control freezing pole, and be furnished with constant temperature and thermal protection device, set for cold insulation layer temperature invariant 25 to 35 degrees centigrade, thermal protection temperature is 40 degrees centigrade.

7. A multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1 or 2, wherein: the controller is provided with a manual trigger, the upper end of the manual trigger is connected with a sealing cover on the liquid nitrogen container through a movable joint, a hemispherical sealing plug is arranged at the position close to the movable joint and corresponds to an exhaust hole of the sealing cover on the liquid nitrogen container to be in an open state or corresponds to a valve at the outlet of a nitrogen gas discharge pipe of the freezing rod to be in a closed state, the lower end of the manual trigger is free and is provided with a reset spring and an electric heating circuit switch, when the lower end of the manual trigger is pressed, the exhaust hole of the sealing cover is sealed by the hemispherical sealing plug, the circuit switch is switched on when the force is increased, and the freezing rod is heated by resistance heating wires on a cold insulation layer and resistance heating wires in the liquid nitrogen container in an electrified mode.

8. A multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1 or 2, wherein: the liquid nitrogen pipe in the freezing rod penetrates through the liquid nitrogen container sealing cover to reach the inside of the liquid nitrogen container, a heat transfer sleeve is arranged outside the liquid nitrogen pipe and is provided with a resistance heating wire, the bottom end of the liquid nitrogen pipe is close to the bottom of the liquid nitrogen container, a filter screen is arranged, the power supply voltage of the resistance heating wire is 5-12V direct current, the power is 15-50W, and the heat transfer sleeve outside the liquid nitrogen pipe penetrates through the liquid nitrogen container sealing cover to be fixed and is connected with a heat absorber.

9. A multi-functional liquid nitrogen cryotherapeutic device according to claim 1 or 8, wherein: the heat absorber is made of metal material with good heat conduction, is in a hollow box shape, is welded with a heat transfer sleeve outside the liquid nitrogen pipe, and is provided with a temperature display screen above the side surface, a power socket at the lower part and a first manual control adjusting valve on the side surface.

10. A multi-functional liquid nitrogen cryotherapeutic apparatus according to claim 1 or 2, wherein: the liquid nitrogen container is a Dewar flask structure container with a vacuum heat insulation layer, the capacity of the liquid nitrogen container is 0.5-30 liters, the liquid nitrogen container is provided with a sealing cover, an electric heating supercharging device, a pressure controller, a manometer and a pressure regulating safety valve, a liquid nitrogen conveying pipe and a nitrogen pipe penetrate through the sealing cover to reach the liquid nitrogen container, the liquid nitrogen pipe is conveyed and extended to be of a hose structure with the electric heating or vacuum heat insulation layer, the other end of the liquid nitrogen pipe is connected with a liquid nitrogen and nitrogen separation device in a handheld liquid nitrogen freezing therapeutic apparatus, and the nitrogen pipe is extended to be connected with a cold insulation layer in a freezing rod through an electric heating element constant temperature structure and the flow of nitrogen is controlled by a second manual control regulating valve.