CN1593601A - Chinese medicinal composition for cholecystitis and preparing method thereof - Google Patents
Chinese medicinal composition for cholecystitis and preparing method thereof Download PDFInfo
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Abstract
The invention discloses a pharmaceutical composition for treating cholecystitis, which is prepared from 25 traditional Chinese medicinal herbs including root of herbaceous peony, lysimachia christinae, curcuma aromatica, Bupleurum root, radix paeoniae rubrathe, root of red rooted saliva, rhizoma corydalis, bitter orange, haw, banksia rose, oriental wormwood, baikal skullcap root, magnolia bark, root bark of tree peony, cyperus tuber, giant knotweed rhizome, Chinese radish seed, toosendan fruit, bighead atractylodes rhizome, frankincense, myrrh, green tangerine orange peel, and rheum officinale.
Description
Technical field:
What the present invention relates to is a kind of Chinese medicine composition for the treatment of cholecystitis and preparation method thereof.
Background technology:
Cholecystitis is clinical comparatively common frequently-occurring disease, its morbidity is also because of comparatively complicated, though chronic and acute branch is arranged, but its cause of disease mostly is liver and gall stasis, damp-heat accumulation or improper diet, disorder of emotion, depression of liver-QI, tired transition and make liver and gall, incoordination between the spleen and stomach smoulder and send out damp and hot, cause the gallbladder morbidity.Cholecystitis is called " gallbladder rises " " gallbladder is strongly fragrant " in the traditional Chinese medical science, the treatment prescription mostly is depressed liver-energy dispersing and function of gallbladder promoting, clearing away heat-damp and promoting diuresis.Mostly be in western medical treatment that based on antiinflammatory then perform the operation gallbladder removal when serious, postoperative bile directly enters intestinal, its clinical effectiveness is unsatisfactory, and regular meeting causes other disease after surgery, and as dyspepsia, bile enters intestinal can bring out colon cancer.Adopting Chinese prescription to treat acute and chronic cholecystitis also has many, mainly be to consider prescription from wet (endogenous dampness), heat (fire of Liver Channel), strongly fragrant (stagnation of QI), the stasis of blood (blood stasis), empty (deficiency of YIN, insufficiency of the spleen) 5 aspects, therefore, each Chinese medicine composition prescription all has its distinctive feature.
Summary of the invention:
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of cholecystitis and preparation method thereof, at cholecystopathy chronicity, outbreak repeatedly, take based on treatment blood stasis, hot and suffocating Therapeutic Method, make the mucosa of degeneration and gallbladder wall blood vessel obtain to a certain degree improvement, the patient removes slight illness for cholecystitis.
Realize that foregoing invention purpose technical scheme is: a kind of Chinese medicine composition for the treatment of cholecystitis is based on treatment blood stasis, gallbladder strongly fragrant (mainly being blood stasis, hot and suffocating), by the Radix Paeoniae Alba, Herba Lysimachiae, Radix Curcumae, Radix Bupleuri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, bran Fructus Aurantii, Fructus Crataegi (parched), the Radix Aucklandiae, Herba Artemisiae Scopariae, Radix Scutellariae, Cortex Magnoliae Officinalis, Massa Medicata Fermentata, Cortex Moutan, Rhizoma Cyperi, Rhizoma Polygoni Cuspidati, Semen Raphani, Endothelium corneum, Fructus Toosendan, Rhizoma Atractylodis Macrocephalae preparata, Olibanum, Myrrha, Pericarpium Citri Reticulatae Viride, Radix Et Rhizoma Rhei totally 25 Chinese medicines of distinguishing the flavor of form; The weight proportion of Chinese medicine of respectively distinguishing the flavor of in the prescription is: Radix Paeoniae Alba 5-10 part, Herba Lysimachiae 10-15 part, Radix Curcumae 10-15 part, Radix Bupleuri 5-10 part, Radix Paeoniae Rubra 5-7 part, Radix Salviae Miltiorrhizae 5-8 part, Rhizoma Corydalis 5-7 part, bran Fructus Aurantii 7-8 part, Fructus Crataegi (parched) 7-8 part, Radix Aucklandiae 5-8 part, Herba Artemisiae Scopariae 5-8 part, Radix Scutellariae 5-7 part, Cortex Magnoliae Officinalis 7-8 part, Massa Medicata Fermentata 7-8 part, Cortex Moutan 5-7 part, Rhizoma Cyperi 5-8 part, Rhizoma Polygoni Cuspidati 5-7 part, Semen Raphani 5-7 part, Endothelium corneum 7-8 part, Fructus Toosendan 5-6 part, Rhizoma Atractylodis Macrocephalae preparata 5-8 part, Olibanum 5-7 part, Myrrha 5-7 part, Pericarpium Citri Reticulatae Viride 5-8 part, Radix Et Rhizoma Rhei 5-6 part.
A kind of preparation method for the treatment of the Chinese medicine composition of cholecystitis is: the Radix Paeoniae Alba in the prescription, Radix Curcumae, Radix Bupleuri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Rhizoma Cyperi, Endothelium corneum, Olibanum, Olibanum, Myrrha, Pericarpium Citri Reticulatae Viride are to be used as medicine after vinegar system, specifically be separately with vinegar spray, vexed with above-mentioned every kind of medicine, after using the slow fire parch then, by square weighing; Fructus Aurantii, Fructus Crataegi, Fructus Toosendan, the Rhizoma Atractylodis Macrocephalae are used as medicine by square weighing after parch; All the other direct weighings of medicine of respectively distinguishing the flavor of are made powder after the above-mentioned Chinese medicine of respectively distinguishing the flavor of mixes.
In the above-mentioned prescription: the Radix Paeoniae Alba nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG is gone into liver, soothing the liver, the resolving depression effect of convergence with strengthening after the vinegar parch; Herba Lysimachiae includes choline, potassium salt etc., and has the bile of promotion to discharge from bile duct, and the energy calculus, has detumescence softening the hard mass, promoting the function of the gallbladder to alleviate jaundice, especially staphylococcus aureus is had inhibitory action; Radix Curcumae is invigorated blood circulation, pain relieving, circulation of qi promoting, resolving depression, removing heat from blood, the function of gallbladder promoting that clears away heart-fire, jaundice eliminating, promotes bile secretion and drainage, and is especially effective to muddy stone, with strengthening the Shugan Zhitong effect after the vinegar parch; Radix Bupleuri reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy with relaxing hot strong property after the vinegar parch, strengthen dispersing the depressed liver-QI for alleviating pain, dissipating depression of QI effect.Above-mentioned four flavor Chinese medicines are formed monarchs drug, have dispersing the depressed liver-QI for alleviating pain, regulate the flow of vital energy, invigorate blood circulation, resolving depression, heat clearing away effect.
The Radix Aucklandiae has the effect in promoting the circulation of QI to relieve pain, the accent; Rhizoma Cyperi depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving stagnate into the Liver Channel effect with enhancing dispersing the depressed liver-QI for alleviating pain and removing food stagnancy, change after the vinegar parch; Fructus Aurantii dispelling the stagnated QI removing food stagnancy, reduce phlegm, remove painful abdominal mass, circulation of qi promoting, alleviating distention in middle-JIAO, remove and expand, parch becomes to have behind the bran Fructus Aurantii and relaxes hot dry property, strengthens to regulate the flow of vital energy and spleen, remove the effect of expanding; Cortex Magnoliae Officinalis dampness is removed full, activating qi for lowering adverse qi; Pericarpium Citri Reticulatae Viride is soothing the liver, dispelling the stagnated QI, eliminating stagnation, disappear stagnantly, and acid content is increased, and relaxes hot dry property with having after the vinegar parch, strengthens pain relieving, removing food stagnancy, change and stagnates and act on; The Fructus Toosendan promoting the circulation of QI to relieve pain, the property of mitigation bitter cold reduces its toxicity after the parch, strengthens the soothing the liver effect that relieves the pain, regulates the flow of vital energy; Radix Et Rhizoma Rhei heat and toxic materials clearing away, clearing away heat-fire, detoxifcation, blood circulation promoting and blood stasis dispelling, and by the cholesterol reducing effect; Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention; Cortex Moutan heat clearing away, removing heat from blood, dissipating blood stasis are with strengthening promoting blood circulation to relieve pain, clearing away heat and cooling blood after the vinegar parch, going into the liver effect; Radix Paeoniae Rubra clearing away heat and cooling blood, blood stasis dispelling relieve the pain; Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, the removing heat from blood pain that disappears, nourishing blood to tranquillize the mind has obvious inhibition gallbladder, the effect of bile duct fibrosis, strengthens blood circulation promoting and blood stasis dispelling after the vinegar system, the effect of relieving the pain; Rhizoma Corydalis is invigorated blood circulation, circulation of qi promoting relieves the pain, and strengthens the circulation of qi promoting effect of relieving the pain after the vinegar system and steams effective ingredient; Rhizoma Polygoni Cuspidati heat-clearing and toxic substances removing, dampness removing, jaundice eliminating, promoting blood circulation and stopping pain, preventing phlegm from forming and stopping coughing; Olibanum, Myrrha promoting blood circulation to relieve pain, detumescence, abirritate after the vinegar system strengthens promoting blood circulation to relieve pain, convergence promoting muscle growth functions and rectifys abnormal smells from the patient; The above-mentioned Chinese medicine of respectively distinguishing the flavor of is formed ministerial drug.
Hawthorn digesting eliminate indigestion, blood circulation promoting and blood stasis dispelling weaken its acidity after the parch, relax the zest to stomach, strengthen the promoting digestion and removing stagnation effect; The Massa Medicata Fermentata stomach function regulating that helps digestion, Semen Raphani promoting digestion and removing stagnation, lowering the adverse-rising QI to resolve phlegm; Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening, dampness diuretic, hidroschesis are antiabortive, and parch becomes Rhizoma Atractylodis Macrocephalae preparata to strengthen function of invigorating spleen, relaxes its dry property; Endothelium Corneum Gigeriae Galli has long-pending, the inducing decomposition of calculi of Sal Nitri, arresting seminal emission, activating the spleen; The above-mentioned Chinese medicine of respectively distinguishing the flavor of is adjuvant drug in the side.
Radix Bupleuri is lifted gas as messenger drug reducing fever by reconciliation, soothing liver-QI for relieving depression, Kaiyang, with the heat clearing away of Radix Et Rhizoma Rhei heat and toxic materials clearing away, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling.
Above monarch, minister, help, make the drug matching of respectively distinguishing the flavor of, bring into play soothing the liver, promoting QI circulation for relieving depression, promoting blood circulation and stopping pain, blood stasis dispelling, purging FU-organs function of gallbladder promoting, Sal Nitri, calculus, litholytic effect jointly.
Above-mentioned prescription is based on powder or fill capsule, each one after each meal, and every day three times, serveing on one month is a course of treatment.Begin to take after four days and can add the fry egg at every turn, heavier as the state of an illness, sick time is longer, the dead point 5% sugar+Radix Astragali 4 (Shanghai), 8 of Radix Salviae Miltiorrhizaes (Shanghai) once a day, logotype 7-14 days is 1 course of treatment, carries out auxiliary treatment, fibrosis or minimizing outbreak repeatedly.The each 5-10g of powder consumption, each 5 of capsule, every 1-2g.
It is 97.9% that above-mentioned prescription is taken the back total effective rate.
Medicine contraindication: annoyed, gastroptosis, anemia of pregnant woman, fatigue have slight stomachache phenomenon behind the clothes.
Above-mentioned prescription is used for the treatment of various acute and chronic cholecystitis, cholelithiasis, cholangitis, bile reflux gastritis, biliary tract ascarid, pancreatitis and biliary postoperative syndrome, gallbladder heart syndrome.
Advantage that the present invention has and good effect: reasonable recipe, evident in efficacy, non-relapse after healing.
The specific embodiment:
Embodiment 1: the Chinese medicine composition prescription of treatment cholecystitis is as follows:
Radix Paeoniae Alba 50g (5 parts), Herba Lysimachiae 100g (10 parts), Radix Curcumae 100g (10 parts), Radix Bupleuri 50g (5 parts), Radix Paeoniae Rubra 50g (5 parts), Radix Salviae Miltiorrhizae 50g (5 parts), Rhizoma Corydalis 50g (5 parts), bran Fructus Aurantii 70g (7 parts), Fructus Crataegi (parched) 70g (7 parts), Radix Aucklandiae 70g (7 parts), Herba Artemisiae Scopariae 50g (5 parts), Radix Scutellariae 50g (5 parts), Cortex Magnoliae Officinalis 70g (7 parts), Massa Medicata Fermentata 70g (7 parts), Cortex Moutan 50g (5 parts), Rhizoma Cyperi 70g (7 parts), Rhizoma Polygoni Cuspidati 50g (5 parts), Semen Raphani 70g (7 parts), Endothelium corneum 70g (7 parts), Fructus Toosendan 50g (5 parts), Rhizoma Atractylodis Macrocephalae preparata 50g (5 parts), Olibanum 50g (5 parts), Myrrha 50g (5 parts), Pericarpium Citri Reticulatae Viride 70g (7 parts), Radix Et Rhizoma Rhei 50g (5 parts).
Preparation method: 1, vinegar system: the Radix Paeoniae Alba with rice vinegar spray, mix thoroughly, vexed, it is yellow that warm fiery parch is; Radix Curcumae is with rice vinegar spray, vexed, and the slow fire parch is little dried; Radix Bupleuri with rice vinegar spray, mix thoroughly, vexed, slow fire parch yellow; Radix Salviae Miltiorrhizae is with rice vinegar spray, vexed, and the slow fire parch is little dried; Rhizoma Corydalis is with rice vinegar spray, vexed, the little yellow heat color of slow fire parch; Cortex Moutan is with rice vinegar spray, vexed, the little yellow of slow fire parch; Rhizoma Cyperi with rice vinegar mix thoroughly, vexed, the little yellow of slow fire parch, appear fragrance; Olibanum sprays, mixes thoroughly with rice vinegar, and is shinny with slow fire parch surface; Myrrha sprays, mixes thoroughly with rice vinegar, and is shinny with slow fire parch surface; Pericarpium Citri Reticulatae Viride with rice vinegar mix thoroughly, vexed, with the little yellow of slow fire parch, appear fragrance;
2, parch: Fructus Aurantii is burnt heat with pot with slow fire earlier, is sprinkled into wheat bran, adds Fructus Aurantii when smoldering, and fast the stir-fry sees that buff takes out, and also can directly buy commercially available finished product; Fructus Crataegi is heated with slow fire, the yellowish heat color of parch; Fructus Toosendan is put into pot and is heated with slow fire, and the parch surface is deep yellow heat color; The Rhizoma Atractylodis Macrocephalae is put into pot and is heated with slow fire, and the parch surface is sallow heat color;
3, above-mentioned Chinese medicine through vinegar system and parch and remaining Chinese medicine are made powder after mixing after by the prescription weighing, by each dose dress bag, bag or adorn capsule.
Clinical effectiveness: adopt to contrast on probation, observe the curative effect, make a definite diagnosis by regular hospital before case is taken medicine.
The treatment group: case is totally 1470 examples, wherein: male patient's 490 examples, female patient 980 examples, age 22-70 year, 41 years old mean age, course of disease 1-15.Take prescription of the present invention, every day 3 times, each 5g.
Contrast groups: case is totally 500 examples, wherein: male patient's 300 examples, female patient 200 examples, age 23-73 year, course of disease 1.3-15.Take medicine: routine is taken the Chinese patent medicine DANSHU, and each 2, every day 3 times, it is fixed that auxiliary antibiotic medicine head draws, each 0.5g, every day 3 times or the each 0.5g in amoxicillin, every day 3 times.
Above-mentioned two groups of administration times were a course of treatment with 1 month, serve on 2 months, and period in a medicine is withdrawn any treatment cholecystitis medicine, avoided tired, annoyed, alcohol prohibition.
Criterion: the disappearance of clinical cure sings and symptoms, ultrasound diagnosis gallbladder size is normal, and gallbladder wall is smooth, and nothing thickens, anacholia deposits, no calculus, follows up a case by regular visits to nothing outbreak in 2 years, produce effects symptom and the disappearance of body card; Ultrasound diagnosis gallbladder size is normal, and gallbladder wall is smooth, nothing thickens, the anacholia alluvial, does not have outbreak in 2 years, and effectively sings and symptoms disappears substantially; Ultrasound diagnosis gallbladder size, gallbladder wall are crude etc. has clear improvement, and idol has outbreak in 1 year, and futile treatment does not have improvement 2 courses of treatment.
The effect contrast:
The clinical observation result contrast table
By table as seen: treatment group cure rate and total effective rate show this Drug therapy cholecystitis and cholelithiasis satisfactory effect all apparently higher than matched group, 5 examples are wherein arranged because of the gastroptosis therapy discontinued in 30 examples, and all the other 25 examples are not taken medicine on request.
Claims (3)
1, a kind of Chinese medicine composition for the treatment of cholecystitis is characterized in that: by the Radix Paeoniae Alba, Herba Lysimachiae, Radix Curcumae, Radix Bupleuri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, bran Fructus Aurantii, Fructus Crataegi (parched), the Radix Aucklandiae, Herba Artemisiae Scopariae, Radix Scutellariae, Cortex Magnoliae Officinalis, Massa Medicata Fermentata, Cortex Moutan, Rhizoma Cyperi, Rhizoma Polygoni Cuspidati, Semen Raphani, Endothelium corneum, Fructus Toosendan, Rhizoma Atractylodis Macrocephalae preparata, Olibanum, Myrrha, Pericarpium Citri Reticulatae Viride, Radix Et Rhizoma Rhei totally 25 the flavor Chinese medicines form; The weight proportion of Chinese medicine of respectively distinguishing the flavor of in the prescription is: Radix Paeoniae Alba 5-10 part, Herba Lysimachiae 10-15 part, Radix Curcumae 10-15 part, Radix Bupleuri 5-10 part, Radix Paeoniae Rubra 5-7 part, Radix Salviae Miltiorrhizae 5-8 part, Rhizoma Corydalis 5-7 part, bran Fructus Aurantii 7-8 part, Fructus Crataegi (parched) 7-8 part, Radix Aucklandiae 5-8 part, Herba Artemisiae Scopariae 5-8 part, Radix Scutellariae 5-7 part, Cortex Magnoliae Officinalis 7-8 part, Massa Medicata Fermentata 7-8 part, Cortex Moutan 5-7 part, Rhizoma Cyperi 5-8 part, Rhizoma Polygoni Cuspidati 5-7 part, Semen Raphani 5-7 part, Endothelium corneum 7-8 part, Fructus Toosendan 5-6 part, Rhizoma Atractylodis Macrocephalae preparata 5-8 part, Olibanum 5-7 part, Myrrha 5-7 part, Pericarpium Citri Reticulatae Viride 5-8 part, Radix Et Rhizoma Rhei 5-6 part.
2, a kind of Chinese medicine composition for the treatment of cholecystitis is characterized in that: the optimum weight proportioning of the Chinese medicine of respectively distinguishing the flavor of in the prescription is: 5 parts of the Radix Paeoniae Albas, 10 parts of Herba Lysimachiaes, 10 parts of Radix Curcumaes, 5 parts of Radix Bupleuri, 5 parts of Radix Paeoniae Rubra, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Rhizoma Corydalis, 7 parts of bran Fructus Aurantiis, 7 parts of Fructus Crataegi (parched), 7 parts of the Radix Aucklandiae, 5 parts of Herba Artemisiae Scopariaes, 5 parts of Radix Scutellariaes, 7 parts of Cortex Magnoliae Officinalis, 7 parts of Massa Medicata Fermentata, 5 parts of Cortex Moutans, 7 parts of Rhizoma Cyperis, 5 parts of Rhizoma Polygoni Cuspidati, 7 parts of Semen Raphanis, 7 parts of Endothelium corneum, 5 parts of Fructus Toosendans, 5 parts of Rhizoma Atractylodis Macrocephalae preparatas, 5 parts of Olibanums, 5 parts of Myrrhas, 7 parts on Pericarpium Citri Reticulatae Viride, 5 parts of Radix Et Rhizoma Rhei.
3, a kind of preparation method for the treatment of the Chinese medicine composition of cholecystitis is: the Radix Paeoniae Alba in the prescription, Radix Curcumae, Radix Bupleuri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Rhizoma Cyperi, Endothelium corneum, Olibanum, Olibanum, Myrrha, Pericarpium Citri Reticulatae Viride are to be used as medicine after vinegar system, specifically be separately with vinegar spray, vexed with above-mentioned every kind of medicine, after using the slow fire parch then, by square weighing; Fructus Aurantii, Fructus Crataegi, Fructus Toosendan, the Rhizoma Atractylodis Macrocephalae are after parch, by square weighing; All the other direct weighings of medicine of respectively distinguishing the flavor of are made powder after the above-mentioned Chinese medicine of respectively distinguishing the flavor of mixes.
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| CN100340284C (en) * | 2005-08-03 | 2007-10-03 | 孙润古 | Jindan gallbladder stone dissolving capsule |
| CN101579413B (en) * | 2008-05-15 | 2011-04-20 | 北京北大维信生物科技有限公司 | Medicinal composition for treating biliary calculus and preparation method thereof |
| CN101658657B (en) * | 2009-08-25 | 2011-05-11 | 路正平 | Drug for treating chronic cholecystitis |
| CN102579973A (en) * | 2012-02-02 | 2012-07-18 | 陈中元 | Medicine for treating gall-stone |
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| CN103316174A (en) * | 2013-07-10 | 2013-09-25 | 朱克兰 | Traditional Chinese medicinal composition for treating acute cholecystitis and preparation method thereof |
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| CN103495116B (en) * | 2013-09-29 | 2015-08-19 | 都匀文学诊所 | The Chinese medicine for the treatment of calculus of intrahepatic duct |
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| CN103768529A (en) * | 2014-02-11 | 2014-05-07 | 王雪雁 | Traditional Chinese medicine composition for treating postchole cystomy syndrome and application thereof |
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| CN1244373C (en) | 2006-03-08 |
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