CN1593599A - Ointment for dispersing breast nodules and preparation method thereof - Google Patents
Ointment for dispersing breast nodules and preparation method thereof Download PDFInfo
- Publication number
- CN1593599A CN1593599A CN 200410043648 CN200410043648A CN1593599A CN 1593599 A CN1593599 A CN 1593599A CN 200410043648 CN200410043648 CN 200410043648 CN 200410043648 A CN200410043648 A CN 200410043648A CN 1593599 A CN1593599 A CN 1593599A
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- China
- Prior art keywords
- rhizoma curcumae
- semen
- chinese medicine
- angelicae dahuricae
- radix
- Prior art date
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- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000002674 ointment Substances 0.000 title claims description 4
- 206010006272 Breast mass Diseases 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000011505 plaster Substances 0.000 claims abstract description 13
- 238000010438 heat treatment Methods 0.000 claims abstract description 9
- 238000003756 stirring Methods 0.000 claims abstract description 5
- 210000000582 semen Anatomy 0.000 claims description 42
- 239000003814 drug Substances 0.000 claims description 29
- 210000000481 breast Anatomy 0.000 claims description 19
- 239000000843 powder Substances 0.000 claims description 19
- 238000000605 extraction Methods 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 5
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims description 4
- 229940126678 chinese medicines Drugs 0.000 claims description 4
- 239000006071 cream Substances 0.000 claims description 4
- 230000006837 decompression Effects 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- 239000012535 impurity Substances 0.000 claims description 4
- 229960003639 laurocapram Drugs 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 238000004064 recycling Methods 0.000 claims description 4
- 238000010992 reflux Methods 0.000 claims description 4
- 235000014375 Curcuma Nutrition 0.000 claims description 3
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 3
- 244000164480 Curcuma aromatica Species 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 3
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 244000163122 Curcuma domestica Species 0.000 abstract 1
- 240000009138 Curcuma zedoaria Species 0.000 abstract 1
- 235000003405 Curcuma zedoaria Nutrition 0.000 abstract 1
- 244000018716 Impatiens biflora Species 0.000 abstract 1
- 235000015912 Impatiens biflora Nutrition 0.000 abstract 1
- 235000009815 Momordica Nutrition 0.000 abstract 1
- 241000218984 Momordica Species 0.000 abstract 1
- 235000005155 Tanacetum balsamita Nutrition 0.000 abstract 1
- 235000003373 curcuma longa Nutrition 0.000 abstract 1
- 239000001812 curcuma zedoaria berg. rosc. Substances 0.000 abstract 1
- 239000004519 grease Substances 0.000 abstract 1
- 235000012907 honey Nutrition 0.000 abstract 1
- 235000019509 white turmeric Nutrition 0.000 abstract 1
- 238000011084 recovery Methods 0.000 description 23
- 230000000694 effects Effects 0.000 description 22
- 238000011282 treatment Methods 0.000 description 8
- 206010006298 Breast pain Diseases 0.000 description 7
- 208000006662 Mastodynia Diseases 0.000 description 7
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 206010014080 Ecchymosis Diseases 0.000 description 3
- 238000007619 statistical method Methods 0.000 description 3
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 241000407170 Curcuma Species 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 206010034754 petechiae Diseases 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 230000027758 ovulation cycle Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000007427 paired t-test Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000000528 statistical test Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a externally used plaster for treating galactophore diseases and method for its preparation, wherein the plaster is prepared from zedoary 153-187, curcuma longa 122-150, garden balsam seed 122-150, root of muskroot-like semiaqilegia 91.8-112.2, momordica seed 30.6-37.4, dahurian angelica root 45.9-56.1 through disintegrating into mesh fines, preparing alcohol extract grease, heating honey and stirring.
Description
Technical field:
The present invention relates to mastotic externally used paste of a kind of treatment and preparation method thereof.
Background technology:
There is the drawback that Chinese medicine ingredients is many, cost is high, curative effect is bad in the mastotic Chinese medicine of existing treatment, and there is the drawback of complex procedures in prior preparation method.
Summary of the invention:
The object of the present invention is to provide a kind of good effect, the simple eliminating stagnation nodules of the breast of preparation section plaster and preparation method thereof, the unguentum of eliminating stagnation nodules of the breast plaster comprises Rhizoma Curcumae, Rhizoma Curcumae Longae, Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, Radix Angelicae Dahuricae Six-element Chinese medicine, and the shared parts by weight of each Chinese medicine are respectively: Rhizoma Curcumae 153～187, Rhizoma Curcumae Longae 122～150, Semen Impatientis 122～150, Radix Semiaquilegiae 91.8～112.2, Semen Momordicae 30.6～37.4, the Radix Angelicae Dahuricae 45.9～56.1.Its preparation method comprises: a. gets Rhizoma Curcumae, curcuma powder is broken into fine powder, crosses 100 mesh sieves, warp
60Behind the Co irradiation, standby; B. after getting Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, Radix Angelicae Dahuricae four Chinese medicine material and being mixed in proportion, be 85% alcohol heating reflux extraction 2 times with accounting for four Chinese medicine gross weight 4 times of amounts, concentration respectively, return time was respectively 1 hour, filter then, it is 1.32 thick paste that merging filtrate, decompression recycling ethanol are concentrated into relative density in the time of 60 ℃, in dry below 60 ℃, be ground into fine powder, cross 100 mesh sieves, standby; Get Mel 1500g, heating dissolves, cross the 180 mesh sieve removal of impurity while hot, the fine powder that when 60, adds above-mentioned Rhizoma Curcumae and Rhizoma Curcumae Longae, stir, after adding the alcohol extraction cream powder of Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, the Radix Angelicae Dahuricae four flavor Chinese medicines and concentration again and be 3% laurocapram, stirred 20 minutes, mixing gets final product.
Eliminating stagnation nodules of the breast plaster of the present invention can be used for cystic hyperplasia of breast, this sick genus traditional Chinese medical science qi depression to blood stasis disease, and disease is seen lump in the breast, accompany mastalgia, mostly be distending pain, scurry pain or twinge, the costa sternales distension increases and decreases with menstrual cycle and emotion changes, dimly red tongue or ecchymosis is arranged, stringy pulse or string are puckery, and it has the effect of promoting flow of QI and blood, mass dissipating and swelling eliminating, and of the present invention have only Six-element Chinese medicine, not only cost is low for it, and good effect, preparation method is simple, is beneficial to apply.
The specific embodiment:
The specific embodiment one: the unguentum in the present embodiment comprises Rhizoma Curcumae, Rhizoma Curcumae Longae, Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, Radix Angelicae Dahuricae Six-element Chinese medicine, and the shared parts by weight of each Chinese medicine are respectively: Rhizoma Curcumae 153～187, Rhizoma Curcumae Longae 122～150, Semen Impatientis 122～150, Radix Semiaquilegiae 91.8～112.2, Semen Momordicae 30.6～37.4, the Radix Angelicae Dahuricae 45.9～56.1; Its preparation method is: a. gets Rhizoma Curcumae, curcuma powder is broken into fine powder, crosses 100 mesh sieves, warp
60Behind the Co irradiation, standby; B. after getting Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, Radix Angelicae Dahuricae four Chinese medicine material and being mixed in proportion, be 85% alcohol heating reflux extraction 2 times with accounting for four Chinese medicine gross weight 4 times of amounts, concentration respectively, return time was respectively 1 hour, filter then, it is 1.32 thick paste that merging filtrate, decompression recycling ethanol are concentrated into relative density in the time of 60 ℃, in dry below 60 ℃, be ground into fine powder, cross 100 mesh sieves, standby; Get Mel 1500g, heating dissolves, cross the 180 mesh sieve removal of impurity while hot, the fine powder that when 60, adds above-mentioned Rhizoma Curcumae and Rhizoma Curcumae Longae, stir, after adding the alcohol extraction cream powder of Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, the Radix Angelicae Dahuricae four flavor Chinese medicines and concentration again and be 3% laurocapram, stirred 20 minutes, mixing gets final product.
The specific embodiment two: the shared parts by weight of each Chinese medicine are respectively in the present embodiment, Rhizoma Curcumae 160, Rhizoma Curcumae Longae 125, Semen Impatientis 125, Radix Semiaquilegiae 95, Semen Momordicae 32, the Radix Angelicae Dahuricae 48.
The specific embodiment three: the shared parts by weight of each Chinese medicine are respectively in the present embodiment, Rhizoma Curcumae 170, Rhizoma Curcumae Longae 136, Semen Impatientis 136, Radix Semiaquilegiae 102, Semen Momordicae 34, the Radix Angelicae Dahuricae 51.
The specific embodiment four: the shared parts by weight of each Chinese medicine are respectively in the present embodiment, Rhizoma Curcumae 182, Rhizoma Curcumae Longae 145, Semen Impatientis 145, Radix Semiaquilegiae 108, Semen Momordicae 37, the Radix Angelicae Dahuricae 54.
The specific embodiment five: the preparation method of present embodiment is as follows: get 1700g Rhizoma Curcumae, 1360g Rhizoma Curcumae Longae, be ground into fine powder, cross 100 mesh sieves, warp
60Behind the Co irradiation, standby; After getting 1360g Semen Impatientis, 1020g Radix Semiaquilegiae, 340g Semen Momordicae, the mixing of 510g Radix Angelicae Dahuricae four Chinese medicine material, be 85% alcohol heating reflux extraction 2 times with accounting for four Chinese medicine gross weight 4 times of amounts, concentration respectively, return time was respectively 1 hour, filter, it is 1.32 thick paste that merging filtrate, decompression recycling ethanol are concentrated into relative density in the time of 60 ℃, in dry below 60 ℃, be ground into fine powder, cross 100 mesh sieves, standby; Get Mel 1500g, heating dissolves, cross the 180 mesh sieve removal of impurity while hot, the fine powder that when 60, adds above-mentioned Rhizoma Curcumae and Rhizoma Curcumae Longae, stir, after adding the alcohol extraction cream powder of Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, the Radix Angelicae Dahuricae four flavor Chinese medicines and concentration again and be 3% laurocapram, stirred mixing 20 minutes.The gained creme is with mould molding (4 * 6.5cm, heavy 5g), and behind all cotton non-woven fabric parcel, (on 7 * 10cm), seal with plastic bag, packing is made 1000 and pasted, promptly to place tensoplast.
Character: this product is pale brown color chips shape plaster, gas perfume (or spice).
The curative effect comprehensive report:
One. the case choice criteria:
1. meet the diagnostic criteria of doctor trained in Western medicine cyclomastopathy.
2. meet the dialectical standard of traditional Chinese medical science syndrome of qi stagnation and blood stasis.
3. the age was 18～55 years old women.
4. informed consent volunteers to be tried and sign the genus Informed Consent Form.
Two, the diagnostic criteria of disease:
1. Western medicine diagnose standard:
(1) mastalgia;
(2) lump in breast;
(3) auxiliary examination: 1. the mammary gland color doppler flow imaging 2. breast molybdenum target X line take the photograph 3. pathological examination of sheet.
2. Chinese medical discrimination standard:
Syndrome of qi stagnation and blood stasis: lump in breast, mastalgia, companion's costa sternales distension, susceptible to lose temper due to restlessness, the few color of menstrual blood volume is dark or clot, abdominal pain during menstruation arranged.Dimly red tongue or petechia, ecchymosis are arranged, white and thin fur, stringy pulse or string are puckery.
(1) primary symptom: lump in breast, mastalgia.
(2) inferior disease: 1. costa sternales distension; 2. susceptible to lose temper due to restlessness; 3. the few color of menstrual blood volume is dark or clot, abdominal pain during menstruation arranged.Tongue is dark red or petechia, ecchymosis, white and thin fur arranged.Pulse condition string or string are puckery.
Three. medicine ingredient: Rhizoma Curcumae, Rhizoma Curcumae Longae, Semen Impatientis, open certain herbaceous plants with big flowers, Semen Momordicae, the Radix Angelicae Dahuricae.
Four. administrated method: external.Earlier the skin affected part is cleaned and wiped away driedly, then lining paper on the plaster is thrown off, medicated core is aimed at the affected part stick.Once a day, each one pastes every subsides content of dispersion 5g.Sticked continuously 28 days.
Five. the criterion of curative effect:
1. clinical recovery: clinical symptoms, sign, lump in breast, mastalgia disappear.
2. produce effects: clinical symptoms, sign, mastalgia obviously alleviate or disappear, and the lump in breast major diameter dwindles more than 1/2.
3. effective: clinical symptoms, sign, mastalgia alleviate or disappear, and the lump in breast major diameter dwindles more than 1/3.
4. invalid: clinical symptoms, sign do not have change, and lump in breast is not seen to have and obviously dwindled or dwindle deficiency.
Six. the analysis of efficacy result, answer the coincidence statistics standard:
The typing of data is responsible for by the specific data manager of PLA General Hospital medical statistics teaching and research room with management.For guaranteeing the accuracy of data, should independently carry out double typing and check and correction by two data managers.
To the query that exists in the case report form, the data administrator will produce FAQ table (DRQ), and send inquiry to researcher by the CRA, researcher should answer and return as early as possible, the data administrator carries out data modification, affirmation and typing according to the answer of researcher, can send DRQ once more in case of necessity.
1. intentional analysis: all are divided into groups through randomization, and use whole cases of a medicine to analyze at least.Intentional analysis carries out at curative effect and adverse events.For the case data of failing to observe whole therapeutic processes, carry over the test final result to last observed data.
2. meet the scheme data analysis: all Pass Test schemes, medication more than 14 days, good, the duration of test of compliance do not use the case of forbidding medication, finishing CRF regulation fill substance, and its curative effect is carried out statistical analysis.
3. statistical analysis adopts SAS 6.12 statistical analysis softwares to calculate.
All statistical test all adopt two-sided test, and the P value is less than or equal to 0.05 difference that will be considered to be checked statistical significance.
The measurement data that each time prescription on individual diagnosis is organized in different treatments will adopt mean ± standard deviation to carry out descriptive statistics.Compare with screening phase basic value, adopt front and back difference in the paired t-test comparable group.The variation of two groups of treatment front and back is adopted variance analysis (ANOVA) row relatively.
The enumeration data that each time prescription on individual diagnosis is organized in different treatments adopts frequency (constituent ratio) to carry out descriptive statistics.X is adopted in the variation of two groups of treatment front and back
2Check or rank test.
| Sequence number | Age | Sex | Occupation | Before the treatment | After the treatment | Curative effect |
| 1 | ?25 | The woman | The nurse | Severe | Recovery from illness | Recovery from illness |
| 2 | ?25 | The woman | The workman | Severe | Slightly | Produce effects |
| 3 | ?26 | The woman | The coroner | Moderate | Recovery from illness | Effectively |
| 4 | ?26 | The woman | The doctor | Severe | Moderate | Effectively |
| 5 | ?28 | The woman | The workman | Severe | Slightly | Produce effects |
| 6 | ?28 | The woman | The peasant | Slightly | Recovery from illness | Recovery from illness |
| 7 | ?28 | The woman | The civil servant | Severe | Slightly | Produce effects |
| 8 | ?30 | The woman | The civil servant | Severe | Slightly | Produce effects |
| 9 | ?30 | The woman | The nurse | Severe | Moderate | Effectively |
| 10 | ?30 | The woman | The workman | Moderate | Slightly | Effectively |
| 11 | ?33 | The woman | The coroner | Severe | Slightly | Produce effects |
| 12 | ?33 | The woman | The doctor | Severe | Slightly | Produce effects |
| 13 | ?33 | The woman | The workman | Slightly | Recovery from illness | Recovery from illness |
| 14 | ?35 | The woman | The peasant | Slightly | Recovery from illness | Recovery from illness |
| 15 | ?36 | The woman | The civil servant | Moderate | Recovery from illness | Recovery from illness |
| 16 | ?36 | The woman | The workman | Severe | Recovery from illness | Recovery from illness |
| 17 | ?39 | The woman | The peasant | Severe | Slightly | Produce effects |
| 18 | ?39 | The woman | Accounting | Moderate | Recovery from illness | Effectively |
| 19 | ?40 | The woman | The office worker | Severe | Moderate | Effectively |
| 20 | ?40 | The woman | Unemployed | Severe | Slightly | Produce effects |
| 21 | ?42 | The woman | Unemployed | Slightly | Recovery from illness | Recovery from illness |
| 22 | ?42 | The woman | The civil servant | Severe | Slightly | Produce effects |
| 23 | ?42 | The woman | The nurse | Severe | Slightly | Produce effects |
| 24 | ?43 | The woman | The workman | Severe | Moderate | Effectively |
| 25 | ?43 | The woman | The coroner | Moderate | Slightly | Effectively |
| 26 | ?44 | The woman | The doctor | Severe | Slightly | Produce effects |
| 27 | ?44 | The woman | The workman | Severe | Slightly | Produce effects |
| 28 | ?44 | The woman | The peasant | Slightly | Recovery from illness | Recovery from illness |
| 29 | ?46 | The woman | The civil servant | Slightly | Recovery from illness | Recovery from illness |
| 30 | ?46 | The woman | The civil servant | Moderate | Recovery from illness | Recovery from illness |
Result: cure rate 33.3%, obvious effective rate 40%, effective percentage 26.7%.
Claims (5)
1, a kind of eliminating stagnation nodules of the breast plaster, it is characterized in that unguentum comprises Rhizoma Curcumae, Rhizoma Curcumae Longae, Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, Radix Angelicae Dahuricae Six-element Chinese medicine, the shared parts by weight of each Chinese medicine are respectively: Rhizoma Curcumae 153～187, Rhizoma Curcumae Longae 122～150, Semen Impatientis 122～150, Radix Semiaquilegiae 91.8～112.2, Semen Momordicae 30.6～37.4, the Radix Angelicae Dahuricae 45.9～56.1.
2, eliminating stagnation nodules of the breast plaster according to claim 1 is characterized in that the shared parts by weight of each Chinese medicine are respectively, Rhizoma Curcumae 160, Rhizoma Curcumae Longae 125, Semen Impatientis 125, Radix Semiaquilegiae 95, Semen Momordicae 32, the Radix Angelicae Dahuricae 48.
3, eliminating stagnation nodules of the breast plaster according to claim 1 is characterized in that the shared parts by weight of each Chinese medicine are respectively, Rhizoma Curcumae 170, Rhizoma Curcumae Longae 136, Semen Impatientis 136, Radix Semiaquilegiae 102, Semen Momordicae 34, the Radix Angelicae Dahuricae 51.
4, eliminating stagnation nodules of the breast plaster according to claim 1 is characterized in that the shared parts by weight of each Chinese medicine are respectively, Rhizoma Curcumae 182, Rhizoma Curcumae Longae 145, Semen Impatientis 145, Radix Semiaquilegiae 108, Semen Momordicae 37, the Radix Angelicae Dahuricae 54.
5, a kind of preparation method of eliminating stagnation nodules of the breast plaster is characterized in that a. gets Rhizoma Curcumae, curcuma powder is broken into fine powder, crosses 100 mesh sieves, and is behind 60Co irradiation, standby; B. after getting Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, Radix Angelicae Dahuricae four Chinese medicine material and being mixed in proportion, be 85% alcohol heating reflux extraction 2 times with accounting for four Chinese medicine gross weight 4 times of amounts, concentration respectively, return time was respectively 1 hour, filter then, it is 1.32 thick paste that merging filtrate, decompression recycling ethanol are concentrated into relative density in the time of 60 ℃, in dry below 60 ℃, be ground into fine powder, cross 100 mesh sieves, standby; Get Mel 1500g, heating dissolves, cross the 180 mesh sieve removal of impurity while hot, the fine powder that in the time of 60 ℃, adds above-mentioned Rhizoma Curcumae and Rhizoma Curcumae Longae, stir, after adding the alcohol extraction cream powder of Semen Impatientis, Radix Semiaquilegiae, Semen Momordicae, the Radix Angelicae Dahuricae four flavor Chinese medicines and concentration again and be 3% laurocapram, stirred 20 minutes, mixing gets final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410043648 CN1251755C (en) | 2004-06-23 | 2004-06-23 | Ointment for dispersing breast nodules and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410043648 CN1251755C (en) | 2004-06-23 | 2004-06-23 | Ointment for dispersing breast nodules and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1593599A true CN1593599A (en) | 2005-03-16 |
| CN1251755C CN1251755C (en) | 2006-04-19 |
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ID=34665357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410043648 Expired - Lifetime CN1251755C (en) | 2004-06-23 | 2004-06-23 | Ointment for dispersing breast nodules and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1251755C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394043A (en) * | 2013-08-15 | 2013-11-20 | 黑龙江鹤翔制药有限责任公司 | Application of stasis-removing paste for nodules of breast for treatment of primary dysmenorrheal and ovarian cyst |
| CN106361960A (en) * | 2016-09-30 | 2017-02-01 | 上海御贴医药科技有限公司 | Traditional Chinese medicine composition capable of treating breast paste and preparation method thereof |
| CN109260426A (en) * | 2018-12-11 | 2019-01-25 | 周金 | A kind of disease eliminating powder junction pain-stopping external use Chinese medicine and its preparation method and application |
| CN112791167A (en) * | 2021-01-12 | 2021-05-14 | 杭州青蜓遵序堂健康管理有限公司 | Preparation process of pain-relieving and stasis-removing hydrogel patch |
-
2004
- 2004-06-23 CN CN 200410043648 patent/CN1251755C/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394043A (en) * | 2013-08-15 | 2013-11-20 | 黑龙江鹤翔制药有限责任公司 | Application of stasis-removing paste for nodules of breast for treatment of primary dysmenorrheal and ovarian cyst |
| CN106361960A (en) * | 2016-09-30 | 2017-02-01 | 上海御贴医药科技有限公司 | Traditional Chinese medicine composition capable of treating breast paste and preparation method thereof |
| CN109260426A (en) * | 2018-12-11 | 2019-01-25 | 周金 | A kind of disease eliminating powder junction pain-stopping external use Chinese medicine and its preparation method and application |
| CN109260426B (en) * | 2018-12-11 | 2021-08-17 | 周金 | External traditional Chinese medicine for eliminating mass, eliminating stagnation and relieving pain and preparation method and application thereof |
| CN112791167A (en) * | 2021-01-12 | 2021-05-14 | 杭州青蜓遵序堂健康管理有限公司 | Preparation process of pain-relieving and stasis-removing hydrogel patch |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1251755C (en) | 2006-04-19 |
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