CN1589812A - Actire pilose deer horn, deer horn, deer bone nano powder and its preparation method - Google Patents
Actire pilose deer horn, deer horn, deer bone nano powder and its preparation method Download PDFInfo
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- CN1589812A CN1589812A CNA031325912A CN03132591A CN1589812A CN 1589812 A CN1589812 A CN 1589812A CN A031325912 A CNA031325912 A CN A031325912A CN 03132591 A CN03132591 A CN 03132591A CN 1589812 A CN1589812 A CN 1589812A
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- cervi
- cornu cervi
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- pantotrichum
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Abstract
An active nanoparticle of pilose antler, deerhorn and deer bone is prepared through breaking and ball grinding. It has higher chemical activity, nutritive value and curative effect.
Description
Technical field:
The present invention is used for the Chinese medicine intensive processing with the nano powder preparation technology, is specifically related to Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi nano powder and preparation method.
Background technology:
Deer country is the earliest supported by China, also is to support one of deer big country.The deer whole body is precious, all can be used as medicine.Cornu Cervi Pantotrichum is meant the still unossified young horn of close living fine hair on male Cervus nippon Temminck or the Cervus elaphus linnaeus head, is traditional famous and precious animal Chinese crude drug, the Compendium of Material Medica record of China Ming Dynasty: " Cornu Cervi Pantotrichum can be mended marrow by spermatogenesis, the Yiyang of nourishing blood, strong muscle key bone, the strong will of QI invigorating." modern medicine study proves, composition such as Cornu Cervi Pantotrichum contains phospholipid, glycolipid, glue fat, hormone, fatty acid, aminoacid, vitamin, protein and calcium, phosphorus, magnesium, receive.Also contain IGF-1 (insulin like growth factor), GHRF-6 bioactie agents such as (GHRFs).Cornu Cervi Pantotrichum has enhancing body immunity, effects such as delaying human body caducity.
The Cornu Cervi Pantotrichum eating method is single now, mainly is based on piece of antler, adopts the steeping in wine bubble, endures ways such as water is used as medicine and eats.Organic solvent extraction such as many employings such as pantocrine fluid injection ethanol prepare, and have destroyed the effective ingredient of Cornu Cervi Pantotrichum, and biological activity is low, and bioavailability is low, and its product purity is not high and have partial solvent residual.
Cornu Cervi is the promptly ossified angle of the ossified thing of Cornu Cervi Pantotrichum.Cornu Cervi can be used as medicine, and the kidney warming sun, bone and muscle strengthening, promoting the circulation of blood repercussive function are arranged.Cure mainly diseases such as impotence and seminal emission, the acid of waist knee joint is cold, acute mastitis swells and ache.Cornu Cervi is taken to endure water and to make Colla cornus cervi.Existing method exists the Cornu Cervi extracts active ingredients few, and is active low, the low deficiency that waits of bioavailability.
Os Cervi has a little less than the tonify deficiency, the effect of strengthening bone and muscle.Cure mainly limbs pain, the cold numbness of muscles and bones etc.The most deer of Os Cervi field abandons Os Cervi, is not utilized, and the minority Os Cervi boils osseocolla and steeps in wine and takes.
Existing method also exists with the same active ingredient extraction of Cornu Cervi few, active low, the low deficiency that waits of bioavailability.
The objective of the invention is to adopt the nano powder preparation method to process Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi nano powder.Nanoscale Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi have high bioactivity, high nutrition, high curative effect, easy absorption, high bioavailability.Can be made into the medicine of dosage forms such as tablet, injection, powder, capsule, microcapsule formulation, oral liquid.Also can add in medicated wine, tonic wine, beverage, the condensed food etc. and use as nutritional health food.
Content of the present invention:
Method of the present invention is to be raw material with Cervus nippon Temminck, Cervus elaphus linnaeus Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi, after cleaning, roguing, decocting in water, drying, coarse pulverization, adopt the nano powder preparation processing method to obtain biologically active and chemically active Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi nano powder.Its main processes is: 1. will be after coarse pulverization, and diameter is respectively charged in the ABQ-100-I type multidimensional swing type ball mill less than the Cornu Cervi Pantotrichum below the 0.25mm, Cornu Cervi, Os Cervi granule.2. to the ball mill energising, start processing.As requested, select process time, with the size of control nanoparticle.3. through processing in 8 hours,, obtain the Cornu Cervi Pantotrichum of size, Cornu Cervi, Os Cervi nano powder less than 100nm (nanometer) in TEM (transmission electron microscope) observation down.
Advantage of the present invention: be to adopt the high-energy ball milling method in the nano powder preparation technology, Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi be processed into biologically active and chemism nanoparticle through multidimensional swing type ball mill.Nanoparticle 3 orders of magnitude that on yardstick, descend, its surface area just improves 6 orders of magnitude, and 6 orders of magnitude are exactly 1,000,000 times, and its curative effect can improve 1,000,000 times in theory.Nanoscale Cornu Cervi Pantotrichum, Cornu Cervi, deer bone powder have high bioactivity, high nutrition, high curative effect, easy absorption, high bioavailability, are novel health-care nutritional food and medicines.
The specific embodiment:
Embodiment of the present invention are as follows: 1. Cornu Cervi Pantotrichum (scraping fine hair), Cornu Cervi, Os Cervi are cleaned, removed impurity, be processed into 3 centimetres of length fragments, the independent decocting in water of Os Cervi 2 hours is removed muscles and fat.2. will be through the Cornu Cervi Pantotrichum after cleaning, roguing, decocting in water are handled, Cornu Cervi, Os Cervi with solarization method or infrared or microwave drying device drying.3. dried Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi are crushed to below the particle diameter 0.25mm with Universalpulverizer respectively.4. nano-powder preparation for processing.Machining process: A. takes by weighing particle diameter Cornu Cervi Pantotrichum, Cornu Cervi, each 500 gram of Os Cervi less than 0.25mm; B. be respectively charged in the ABQ-100-I type multidimensional swing type ball mill; C. to ball mill energising startup work, continuous operation was shut down after 8 hours; D. take out Cornu Cervi Pantotrichum, Cornu Cervi, the deer bone powder of processing respectively,, obtain Cornu Cervi Pantotrichum, Cornu Cervi, the Os Cervi nano powder of size less than 100nm (nanometer) in TEM (transmission electron microscope) observation down.
Following preference is described further the application of active hairy antler, Cornu Cervi, Os Cervi nano powder, but does not limit range of application of the present invention.
Example: the size that will obtain by multidimensional swing type ball mill processing less than the Cornu Cervi Pantotrichum of 100 nanometers or Cornu Cervi or Os Cervi nano powder 500 grams add fully dissolving is housed in the double centner 38 degree high-quality grain Chinese liquor jars after, cannedly advance in the 500 gram volume bottles, promptly obtain 200 bottles of content and be 5/1000ths active nano Cornu Cervi Pantotrichum or Cornu Cervi or Os Cervi tonic wine.
Claims (6)
1, a kind of is raw material with Cervus nippon Temminck, Cervus elaphus linnaeus Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi, obtains biologically active and chemically active Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi nano powder through cleaning, roguing, decocting in water, drying, coarse pulverization, the processing of nano powder preparation method.
2. according to the described cleaning of claim 1, roguing, water boiling method is cleaned Cornu Cervi Pantotrichum (scraping fine hair) or Cornu Cervi or Os Cervi, removes impurity, is processed into 3 centimetres of length fragments, and the independent decocting in water of Os Cervi 2 hours is removed muscles and fat.
3. according to the described drying means of claim 1: Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi can adopt solarization method, method of making herbs dry gradually in the shade or infrared, microwave drying device drying means.
4. according to the described coarse pulverization of claim 1; Available Universalpulverizer with Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi pulverize separately to particle diameter 0.25mm.
5. described according to claim 1, the nano powder preparation method; It is characterized in that passing through to select process time with ABQ-100-I type multidimensional swing type ball mill respectively through coarse pulverization to the Cornu Cervi Pantotrichum below the diameter 0.25mm, Cornu Cervi, Os Cervi, the size of control nanoparticle, the processing continuously through 8 hours, observation obtains Cornu Cervi Pantotrichum, Cornu Cervi, the Os Cervi nano powder of size less than 100nm (nanometer) under TEM (transmission electron microscope).
6. according to dosage form medicine and tonic wine, medicated wine, beverage, nutrition and food such as the made various powder of the described biologically active that obtains of claim 1 and chemism Cornu Cervi Pantotrichum, Cornu Cervi, Os Cervi nano powder, tablet, injection, oral liquid, capsule, microcapsule formulations.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031325912A CN1589812A (en) | 2003-09-02 | 2003-09-02 | Actire pilose deer horn, deer horn, deer bone nano powder and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031325912A CN1589812A (en) | 2003-09-02 | 2003-09-02 | Actire pilose deer horn, deer horn, deer bone nano powder and its preparation method |
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| Publication Number | Publication Date |
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| CN1589812A true CN1589812A (en) | 2005-03-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA031325912A Pending CN1589812A (en) | 2003-09-02 | 2003-09-02 | Actire pilose deer horn, deer horn, deer bone nano powder and its preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101283783B (en) * | 2007-01-25 | 2011-09-21 | 钟世杰 | Edible health collocryst and its preparation method |
| CN101569417B (en) * | 2009-05-31 | 2012-05-02 | 南昌大学 | Method for manufacturing nanometer bovine bone powder |
| CN102845659A (en) * | 2011-07-01 | 2013-01-02 | 湖南晟通科技集团有限公司 | Velvet jelly and its preparation method |
-
2003
- 2003-09-02 CN CNA031325912A patent/CN1589812A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101283783B (en) * | 2007-01-25 | 2011-09-21 | 钟世杰 | Edible health collocryst and its preparation method |
| CN101569417B (en) * | 2009-05-31 | 2012-05-02 | 南昌大学 | Method for manufacturing nanometer bovine bone powder |
| CN102845659A (en) * | 2011-07-01 | 2013-01-02 | 湖南晟通科技集团有限公司 | Velvet jelly and its preparation method |
| CN102845659B (en) * | 2011-07-01 | 2016-03-23 | 湖南晟通科技集团有限公司 | A kind of pilose antler jelly and preparation method thereof |
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Addressee: Song Debin Document name: Notice of application for publication of patent for invention and entry into the substantive examination procedure |
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