CN1562242A - Capsule of burnet for raising white cell and preparation method - Google Patents
Capsule of burnet for raising white cell and preparation method Download PDFInfo
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- CN1562242A CN1562242A CN 200410023044 CN200410023044A CN1562242A CN 1562242 A CN1562242 A CN 1562242A CN 200410023044 CN200410023044 CN 200410023044 CN 200410023044 A CN200410023044 A CN 200410023044A CN 1562242 A CN1562242 A CN 1562242A
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- burnet
- capsule
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- fine powder
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Abstract
A capsule of sanguisorba root for treating leukocytopenia is prepared through pulverizing sanguisorba root, adding auxiliary and loading in capsules.
Description
Technical field:
The present invention relates to a kind of Chinese medicinal capsule agent and process for making thereof, relate in particular to garden-Burnet-Sheng-Bai capsules and preparation method thereof.
Background technology:
Capsule, changes dosage form and manages as new drug research according to the relevant laws and regulations of China's drug control as a kind of pharmaceutical dosage form.The original dosage form of this product is a tablet, has listed the national drug ministry standard in.
The technology features of former tablet is with after the prescription pulverizing medicinal materials, adds suitable adjuvant and mixes, and granulation, drying, tabletting, sugar coating, promptly.
Existing burnet for raising white cell tablet exists disintegration than shortcomings such as length.
Summary of the invention:
The Chinese medicine Rhizoma sanguisorbae preparation and preparation method thereof that the purpose of this invention is to provide the treatment leukopenia of the rapid disintegrate of a kind of energy overcomes the above-mentioned drawback of prior art, improves the quality and the curative effect of product, satisfies the needs of medical treatment better.
Technical solution of the present invention is a kind of garden-Burnet-Sheng-Bai capsules, is a kind of Chinese medicine for the treatment of leukopenia, it is characterized in that it is that main component is the capsule of Chinese medicine Radix Sanguisorbae.
The preparation method of garden-Burnet-Sheng-Bai capsules is:
(1) gets the Radix Sanguisorbae medical material, concoct into clean medical material, get clean medical material, be ground into the fine powder of particle diameter less than 100um by the pharmacopeia regulation;
(2) get (1) gained fine powder, add adjuvant, directly encapsulating capsule, or adding binding agent is granulated, dry back encapsulating capsule, that is and, every capsules contains Radix Sanguisorbae fine powder 5-20mg;
Adjuvant is: one or more various combination in lactose, calcium sulfate, sucrose, carboxymethyl starch sodium, Pulvis Talci, xylitol, magnesium stearate, starch, soluble starch, dextrin, microcrystalline Cellulose, sodium carboxymethyl cellulose, polyvinylpolypyrrolidone, 30 POVIDONE K 30 BP/USP 30, low-substituted hydroxypropyl cellulose, the micropowder silica gel; Optimum amount is 5% microcrystalline Cellulose, 8% low-substituted hydroxypropyl cellulose, 2% Pulvis Talci;
Binding agent is: the ethanol of 30 POVIDONE K 30 BP/USP 30 and aqueous solution, starch slurry, dextrin slurry, syrup; Optimum amount is 8% starch slurry.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of garden-Burnet-Sheng-Bai capsules, it contains main component and is: Radix Sanguisorbae.
The garden-Burnet-Sheng-Bai capsules preparation method is
(1) gets the Radix Sanguisorbae medical material and concoct into clean medical material, get clean medical material, be ground into the fine powder of particle diameter less than 100um by the pharmacopeia regulation;
(2) with (1) gained fine powder, the adding adjuvant is: 5% microcrystalline Cellulose, 8% low-substituted hydroxypropyl cellulose, 2% Pulvis Talci, and the starch slurry system soft material with 8% is granulated, drying, the fill capsule, every material inventory is 0.2g;
To produce 1000 garden-Burnet-Sheng-Bai capsules is example, gets Radix Sanguisorbae fine powder 5g, adds adjuvant to be: 10g microcrystalline Cellulose, 16g low-substituted hydroxypropyl cellulose, 4g Pulvis Talci.
Advantage of the present invention is:
Garden-Burnet-Sheng-Bai capsules is easy to carry, rapidly disintegration, and little, the taking convenience of dose is conducive to improve curative effect, Satisfy better the treatment needs.
Claims (2)
1, a kind of garden-Burnet-Sheng-Bai capsules is a kind of Chinese medicine for the treatment of leukopenia, it is characterized in that it is that main component is the capsule of Chinese medicine Radix Sanguisorbae.
2, a kind of preparation method of garden-Burnet-Sheng-Bai capsules is characterized in that:
(1) gets the Radix Sanguisorbae medical material, concoct into clean medical material, get clean medical material, be ground into the fine powder of particle diameter less than 100um by the pharmacopeia regulation;
(2) get (1) gained fine powder, add adjuvant, directly encapsulating capsule, or adding binding agent is granulated, dry back encapsulating capsule, that is and, every capsules contains Radix Sanguisorbae fine powder 5-20mg;
Adjuvant is: one or more various combination in lactose, calcium sulfate, sucrose, carboxymethyl starch sodium, Pulvis Talci, xylitol, magnesium stearate, starch, soluble starch, dextrin, microcrystalline Cellulose, sodium carboxymethyl cellulose, polyvinylpolypyrrolidone, 30 POVIDONE K 30 BP/USP 30, low-substituted hydroxypropyl cellulose, the micropowder silica gel; Optimum amount is 5% microcrystalline Cellulose, 8% low-substituted hydroxypropyl cellulose, 2% Pulvis Talci;
Binding agent is: the ethanol of 30 POVIDONE K 30 BP/USP 30 and aqueous solution, starch slurry, dextrin slurry, syrup; Optimum amount is 8% starch slurry.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410023044 CN1562242A (en) | 2004-03-31 | 2004-03-31 | Capsule of burnet for raising white cell and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410023044 CN1562242A (en) | 2004-03-31 | 2004-03-31 | Capsule of burnet for raising white cell and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1562242A true CN1562242A (en) | 2005-01-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410023044 Pending CN1562242A (en) | 2004-03-31 | 2004-03-31 | Capsule of burnet for raising white cell and preparation method |
Country Status (1)
| Country | Link |
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| CN (1) | CN1562242A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102100773A (en) * | 2009-05-26 | 2011-06-22 | 成都地奥制药集团有限公司 | Low dosage burnet root solid preparation |
| CN106265863A (en) * | 2016-08-30 | 2017-01-04 | 山东百维药业有限公司 | A kind of vitacoenzyme compositions, hard capsule comprising said composition and preparation method thereof |
| CN115998703A (en) * | 2022-12-14 | 2023-04-25 | 迪沙药业集团有限公司 | Sanguisorba composition and preparation method thereof |
-
2004
- 2004-03-31 CN CN 200410023044 patent/CN1562242A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102100773A (en) * | 2009-05-26 | 2011-06-22 | 成都地奥制药集团有限公司 | Low dosage burnet root solid preparation |
| CN106265863A (en) * | 2016-08-30 | 2017-01-04 | 山东百维药业有限公司 | A kind of vitacoenzyme compositions, hard capsule comprising said composition and preparation method thereof |
| CN115998703A (en) * | 2022-12-14 | 2023-04-25 | 迪沙药业集团有限公司 | Sanguisorba composition and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |