CN1562098A - Method for preparing liver protective and sobering preparation - Google Patents
Method for preparing liver protective and sobering preparation Download PDFInfo
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- CN1562098A CN1562098A CN 200410008768 CN200410008768A CN1562098A CN 1562098 A CN1562098 A CN 1562098A CN 200410008768 CN200410008768 CN 200410008768 CN 200410008768 A CN200410008768 A CN 200410008768A CN 1562098 A CN1562098 A CN 1562098A
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Abstract
A medicine for sobering up and protecting liver is prepared from sophora flower, pueraria leaf, wolfberry fruit, prunella spike and chrysanthemum flower.
Description
Technical field:
The present invention relates to a kind of preparation method of health-care beverage, be specifically related to a kind of preparation method of preparation for protecting liver and relieving acute alcoholism, belong to International Classification of Patents A61K35/78 technical field.
Background technology:
Along with the raising of people's living standard, the consumption of inebriant is more and more universal.E-at pleasure, drink with measure has positive function and significance, and that the excessive drinking meeting brings to drinking person is uncomfortable, and severe patient can liver injury, to healthy totally unfavorable.
Summary of the invention:
Purpose of the present invention is to provide a kind of preparation method that can protect the healthy a kind of preparation for protecting liver and relieving acute alcoholism of alcohol user.
Technical scheme of the present invention is as follows:
Preparation for protecting liver and relieving acute alcoholism wherein contains glycoside, flavonoid isoreactivity material, specifically contains: Radix Puerariae flavone, puerarin, Flos Chrysanthemi lactone, Flos Chrysanthemi alcohol, Palmic acid, ursolic acid, daucosterol, β one face cream alcohol, alkaloid, Flos Sophorae first element, glucose, rhamnose and fructose.
Raw material that preparation for protecting liver and relieving acute alcoholism of the present invention is used and amount ratio: Flos Sophorae extract 1 gram; Folium Puerariae loatae extract 2 grams; Fructus Lycii 15 grams; Spica Prunellae 15 grams; Flos Chrysanthemi 12 grams.
Concrete compound method:
1. the preparation of Folium Puerariae loatae: after the Folium Puerariae loatae harvesting, shredding in 8 hours, wide about 1.3cm～1.5cm, directly drop in about 80 ℃ the hot water and soaked 15 minutes, carrying out slag liquid separates, 60 ℃ of vacuum concentration of low temperature carry out drying and crushing for 60～80 ℃ in temperature then to thick paste, are without prejudice with the active substance that guarantees material;
2. Flos Sophorae leaching process: Flos Sophorae is directly dropped into 80 ℃ of left and right sides hot water, soaked 15 minutes, carry out slag liquid and separate, 60 ℃ of vacuum concentration of low temperature, temperature is carried out drying and crushing for 60～80 ℃, is without prejudice with the active substance that guarantees material;
3. Fructus Lycii, Spica Prunellae, Flos Chrysanthemi leaching process: Fructus Lycii, Spica Prunellae, Flos Chrysanthemi are through selected, after cleaning, roguing etc. are concocted, drop in the extraction pot simultaneously, add five times of water, in 98～100 ℃ of slight boiling conditions, extracted 45 minutes, carry out slag liquid and separate, extracting solution carries out drying and crushing for 60～80 ℃ at low temperature, is without prejudice with the active substance that guarantees material.
4. above extraction of substance gets final product according to above-mentioned precision proportioning mixing.
The specific embodiment:
Get Flos Sophorae extract 10 grams; Folium Puerariae loatae extract 20 grams; Fructus Lycii 150 grams; Spica Prunellae 150 grams; Flos Chrysanthemi 120 grams.
Carry out pretreatment by above-mentioned steps, and the proportioning mixing, promptly can be made into preparation for protecting liver and relieving acute alcoholism.
The effect that the present invention is useful:
Nourishing the liver and kidney; Heat-clearing and toxic substances removing; Hepatoprotective makes eye bright; Promoting diuresis to clear away damp pathogen; By to human body intestinal, stomach, lung, the accent of interior tissue organs such as spleen, liver, kidney is mended, tonneau, and acceleration of alcohol decomposes, and through defecation the wet alcoholism of wine is excreted the effect of sobering up, relieving the effect of alcohol to reach.
Pharmacology analysis:
(1) Fructus Lycii: the meridian distribution of property and flavor sweet in the mouth, property is flat.Return liver, kidney, lung meridian.Its main polysaccharide, betanin and carotene of containing.Can strengthen and regulate immunologic function, strengthen hemopoietic function, the rising peripheral leukocytes strengthens reticuloendothelial system phagocytic activity; Suppress tumor, slow down aging; Reduce blood cholesterol, suppress atherosclerosis and form; The protection liver plasma membrane promotes liver cell regeneration, anti-fatty liver, and the protection toxic hepatitis suppresses hepatocarcinoma; Blood sugar lowering; The effect of estrogen sample; Blood pressure lowering; Anoxia enduring, resisting fatigue, mutation.
(2) Flos Chrysanthemi: bitter in the mouth, suffering, cool in nature.Return lung, Liver Channel.It contains yejuhua lactone, chrysanthemol, chrysanthetriol, Flos Chrysanthemi Indici ketone, chrysanthenone, acacetin, Palmic acid, ursolic acid, linoleic acid, volatilization wet goods.
(3) Radix Puerariae: sweet in the mouth, suffering, property is flat.Return spleen, stomach warp.Radix Puerariae total flavones can be expanded brain and arteria coronaria blood vessel, and blood flow increasing reduces myocardial oxygen consumption, increases the oxygen supply; Puerarin is brought down a fever, blood pressure lowering, and calmness, blood sugar lowering and serum cholesterol suppress platelet aggregation, relieve muscle spasms; Its decoct can strengthen leukocytes phagocytic staphylococcus aureus ability, suppresses dysentery bacterium.
(4) Spica Prunellae: acrid in the mouth, hardship, cold in nature.Return the liver and gall warp.The master contains triterpenoid saponin, and glycoside unit is oleanolic acid, ursolic acid.Also contain daucosterol, globulariacitrin, hyperin, β-face cream alcohol, caffeic acid, senior satisfied fatty acid, alkaloid.The energy blood pressure lowering, anti-arrhythmia; Antiinflammatory; Immunosuppressant; Antibacterium, fungus, anti AIDS virus and herpes simplex, anti-cell poison; Blood sugar lowering; Anticoagulation, anti-myocardial infarction, excited uterus strengthens enterokinesia.
(5) Flos Sophorae: bitter in the mouth, cold nature.Return liver, large intestine channel.Flos Sophorae contains content height in globulariacitrin (rutin), the alabastrum, Flos Sophorae first element, second element, third element, tannin, glucose, rhamnose.Can bring high blood pressure down, prevent rupture of blood vessel in brain; Strengthen cardiac contractile force and output, decreased heart rate, the expansion coronary vasodilator improves the cardiac muscle circulation, reduces myocardial oxygen consumption, reduces liver, aorta and blood cholesterol amount, prevention and treatment arteriosclerosis; Antiinflammatory; Reduce the tension force of intestinal, bronchial smooth muscle, have spasmolytic, antiulcer action; Can reduce the stomach motor function.
Toxicological experiment:
" preparation for protecting liver and relieving acute alcoholism " belongs to nontoxic product.Give the high dose of rat 37000mg/kg, the phenomena of mortality do not take place; Dog oral this product 1800mg/kg every day, toxicity reflection (comprising the section analysis) continuous 6 months, does not take place to each histoorgan in rat oral this product 3000mg/kg every day.
Claims (4)
1, a kind of preparation method of preparation for protecting liver and relieving acute alcoholism is characterized in that: used raw material and amount ratio are: Flos Sophorae extract 1 gram; Folium Puerariae loatae extract 2 grams; Fructus Lycii 15 grams; Spica Prunellae 15 grams; Flos Chrysanthemi 12 grams.
2, the preparation method of preparation for protecting liver and relieving acute alcoholism according to claim 1, it is characterized in that: the preparation steps of described Folium Puerariae loatae is: after Folium Puerariae loatae is plucked, shredding in 8 hours, wide about 1.3cm～1.5cm, directly drop in about 80 ℃ the hot water and soaked 15 minutes, carry out slag liquid and separate, 60 ℃ of vacuum concentration of low temperature carry out drying and crushing for 60～80 ℃ in temperature then to thick paste.
3, the preparation method of preparation for protecting liver and relieving acute alcoholism according to claim 1, it is characterized in that: the preparation steps of described Flos Sophorae is: Flos Sophorae is directly dropped into 80 ℃ of left and right sides hot water, soaked 15 minutes, carry out slag liquid and separate, 60 ℃ of vacuum concentration of low temperature, temperature is carried out drying and crushing for 60～80 ℃.
4, the preparation method of preparation for protecting liver and relieving acute alcoholism according to claim 1, it is characterized in that: described Fructus Lycii, Spica Prunellae, Flos Chrysanthemi leaching process are: with Fructus Lycii, Spica Prunellae, Flos Chrysanthemi through selected, after cleaning, roguing etc. are concocted, drop in the extraction pot simultaneously, add five times of water, extracted 45 minutes in 98～100 ℃ of slight boiling conditions, carry out slag liquid and separate, extracting solution carries out drying and crushing for 60～80 ℃ at low temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410008768 CN1562098A (en) | 2004-03-18 | 2004-03-18 | Method for preparing liver protective and sobering preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410008768 CN1562098A (en) | 2004-03-18 | 2004-03-18 | Method for preparing liver protective and sobering preparation |
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| Publication Number | Publication Date |
|---|---|
| CN1562098A true CN1562098A (en) | 2005-01-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN 200410008768 Pending CN1562098A (en) | 2004-03-18 | 2004-03-18 | Method for preparing liver protective and sobering preparation |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1853508B (en) * | 2005-04-19 | 2010-11-03 | 韩国养药多股份有限公司 | Composition for the improvement of liver function, the reduction of serum ethanol level and antioxidant activity enhancement |
| CN108324751A (en) * | 2018-05-14 | 2018-07-27 | 浙江医药高等专科学校 | A kind of elegant jessamine alcohol extracts from the leaves and its purposes in relieving alcoholism and protecting liver |
-
2004
- 2004-03-18 CN CN 200410008768 patent/CN1562098A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1853508B (en) * | 2005-04-19 | 2010-11-03 | 韩国养药多股份有限公司 | Composition for the improvement of liver function, the reduction of serum ethanol level and antioxidant activity enhancement |
| CN108324751A (en) * | 2018-05-14 | 2018-07-27 | 浙江医药高等专科学校 | A kind of elegant jessamine alcohol extracts from the leaves and its purposes in relieving alcoholism and protecting liver |
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