CN1559287A - Food for supplementing estrogen to human body and regulating intenstinal bacilli, and its prepn. method - Google Patents
Food for supplementing estrogen to human body and regulating intenstinal bacilli, and its prepn. method Download PDFInfo
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- CN1559287A CN1559287A CNA2004100100970A CN200410010097A CN1559287A CN 1559287 A CN1559287 A CN 1559287A CN A2004100100970 A CNA2004100100970 A CN A2004100100970A CN 200410010097 A CN200410010097 A CN 200410010097A CN 1559287 A CN1559287 A CN 1559287A
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- isoflavones
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Abstract
A food for supplementing estrogen to human body and regulating the intenstinal bacilli is prepared from soybean isoflavone, bifidobacteria, lactolin and VC1.
Description
Technical field:
The present invention is specifically related to a kind of additional human body estrogen and food of regulating gut flora and preparation method thereof.
Technical background:
Along with becoming increasingly abundant of the development of society, material life, people life style also changes thereupon, and the grain of eating, vegetables also has residual highly effective pesticide, and these all cause women's estrogen secretion inequality easily, the function of intestinal canal imbalance, and constipation patient is increasing.At present, food, function ratio that people eat are more single, do not have a kind of food can replenish human body estrogen and can regulate human body intestinal canal flora again.
Summary of the invention:
The purpose of this invention is to provide a kind of human body estrogen that can replenish and to regulate food of human enteric bacteria and preparation method thereof again.
The technical scheme that the present invention takes by isoflavones, Oilgosaccharkdes, lactein and vitamin C through processing and make, its content by weight percentage: isoflavones 65-80%, Oilgosaccharkdes 10-25%, lactein 9-12%, vitamin C 1-2%;
The present invention makes by the following method:
1, raw material is handled: the soybean meal powder of gained after the soybean degreasing is broken, grain warp is that 0.5mm-0.8mm is standby;
2, solvent extraction: adopt ethanol water to extract, concentration of alcohol is 40%-80%, and solvent and raw material are pressed (8-16): 1 (volume ml/ weight g) puts continuous flow upstream, immerses in the jar, extracts 50 ℃-90 ℃ of temperature, and extraction time is 3 times, extraction time 3h-10h;
3, separate: filter leachate, reclaim ethanol, leave standstill make precipitation fully after, carry out centrifugation, dry sediment, it is standby promptly to get the isoflavones meal.
4, lactic acid bacteria culture medium: beef extract: peptone: multitudinous sugar: sodium chloride: calcium carbonate=0.5%: 2.5%: 2%: 0.5%: 1% charge ratio feeds intake;
5, inoculation, cultivation: the sucrose solution and the good big bottle liquid medium of lactobacter growth that will be cooled to below 40 ℃ are successively all poured in the jar, close immediately after the batching hole sterilization, stir 15 fens kinds, 35 ℃-37 ℃ leave standstill cultivation, stirred 10 minutes in per 2 hours, and cultivated and got zymotic fluid in 10-16 hour;
6, filter: get calcium carbonate and distilled water furnishing pasty state, become filtering layer in the impouring nutsch filter, pour zymotic fluid, suction filtration into, make filter cake, it is standby promptly to get dry powder of lactic acid bacteria after drying, the pulverizing;
7, mix: take by weighing isoflavones powder, lactic acid bacteria powder, vitamin C, Oilgosaccharkdes respectively according to prescribed dose and mix with progressively dilution method and lactic acid bacteria cake, cross 80 mesh sieves through chemically examine qualified after filling.
Because the present invention has taked technique scheme, isoflavones is the mixture of Polyphenols, comprises genistein, daidzein, Glycitein, and its pharmacological action is:
1, antitumor action, isoflavones can make that glutathione peroxidase transfers to normally in the liver neoplasm, suppress breast tumor cell propagation and differentiation during the genistein high dose;
2, the protective action of angiocardiopathy 1. ldl receptor regulate 4. anti-thrombosis function of propagation that 3. 2. anti-oxidant rerum natura suppress VSMC
3, the interaction energy to the bone metabolism prevents that bone density from descending, and can lower induced osteoporosis disease.
Isoflavones has special estrogenic antagonist.When the human body estrogen level is higher, isoflavones can be easy to pass through cell membrane, than the quicker receptor protein position that occupies of body inner estrogen, to stop body inner estrogen and receptors bind, reduced estrogen level, reduce stimulation simultaneously, thereby improve the proliferation of mammary gland and fibroid receptor protein.
The function of Oilgosaccharkdes (oligoisomaltose):
1, promotes Bifidobacterium propagation
The Bifidobacterium oligoisomaltose (Oilgosaccharkdes) that can ferment produces short chain fatty acid (mainly being acetic acid and lactic acid) and some antibiotic materials, thereby suppress the generation and the breeding of intrinsic putrefactivebacteria in exogenous pathogenic bacteria and the enteron aisle, by the microorganism antagonism, harmful bacterium is played competition row tear effect open; By a kind of antibacterial material that Bifidobacterium produces, it can suppress Shigella, Sha Shi bacillus, Staphylococcus aureus, Escherichia coli and some other microorganism effectively.
2, prevent constipation
The SCFA that bifidobacterium fermentation oligoisomaltose (Oilgosaccharkdes) produces can stimulate intestines peristalsis, increases the ight soil wettability, and keeps certain osmotic pressure, thereby prevent constipation; Because Oilgosaccharkdes is by improving intestinal microbial balance, fundamentally recover the normal functions of expelling toxin of enteron aisle, therefore can not producing dependence, the resistance to the action of a drug as taking cathartic; Can not produce other toxic and side effects, belong to healthy ecological detoxicating intestine food.
3, suppress pathogen and diarrhoea
The proliferation function of oligoisomaltose (Oilgosaccharkdes) can suppress pathogen effectively, reduces the quantity of harmful bacterium in the enteron aisle; Probiotics is set up the beachhead head rapidly and is faced upward system pathogen and diarrhoea in alimentary canal.
4, liver function protecting
Take in the formation that oligomeric maltose (Oilgosaccharkdes) can reduce the toxic metabolite product; Alleviate the burden that liver divides toxolysin.Can influence the 26S Proteasome Structure and Function of intestinal flora during dysfunction of liver; After certain digestive disease research institute takes the oligomeric different table bud sugar in 27 gram/skies for 56 years old and have for many years cirrhosis and the normal patient who diarrhoea occurs, hepatocirrhosis symptoms alleviation, the abdomen also improvement of rising.
5, reduce serum cholesterol
Taking oligoisomaltose (Oilgosaccharkdes) can make the amount of serum cholesterol obviously descend.Can reduce serum cholesterol 20-50 milliliter in thoughtful 3 months as taking in 15-30 gram oligoisomaltose 2 every day.
6, be better than oligoisomaltose (Oilgosaccharkdes) and do not digested, so be referred to as low molecular mass again, non-stickiness, water miscible dietary fiber by human consumption liquid; Than dietary fiber superior be that its intake has certain sweet taste the end of than, and is water-soluble fully, can be added in any food, and not influence the original local flavor of food, do not increase viscosity, do not influence the absorption of minerals and vitamins.In addition, the diabetic becomes and can relievedly eat.
Lactic acid bacteria is a group energy produces the gram-positive bacterium of a large amount of lactic acid from the fermentability carbohydrate common name, extensively is present in people, animal, fowl enteron aisle, numerous food product, material and the minority clinical sample.Studies show that in a large number, lactic acid bacteria can be regulated the body gastrointestinal tract normal flora, keep microecological balance, improve food digestion rate and biological value, reduce serum cholesterol, the control endotoxin suppresses the generation of interior corrupt bacteria growing breeding of enteron aisle and spoilage product, makes nutriment, stimulate tissue development, thereby to nutritional status, physiological function, cell infection, drug effect, toxic reaction immune response, tumour generation, aging course and the unexpected generation effects such as emergency reaction of body.This shows that the physiological function of lactic acid bacteria and the vital movement of body are closely bound up.We can say that if lactic acid bacteria stops growing, humans and animals just is difficult to healthy existence; It has following function:
1, can regulate the body gastrointestinal tract normal flora, produce specific enzymes system, keep the intestinal microecology balance, promote body health, improve food digestion rate and biological value.
2, have adhesiveness and field planting ability, it is participated in directly and constitutes field planting and the invasion that enteron aisle field planting drag stops pathogen, to the nutritious effect of enteron aisle, help the reparation of gut barrier, can strengthen the cytophagous vigor of host, the excessive multiplication that can suppress Gram-negative bacteria is indirectly regulated flora imbalance.
3, produce the metabolite of bacteriostatic activity, the lactic acid and the organic acid that produce can significantly reduce pH value, make to be in sour environment in the intestines, and EH can promote gastrointestinal motility to keep normal physiological function, prevent the field planting of pathogenic bacteria, the H202 of generation can suppress and kill G bacterium, Escherichia coli, salmonella.
4, reduce cholesterol, the metabolizable energy of lactic acid bacteria significantly reduces the absorption of intestinal tube to cholesterol, and lactic acid bacteria absorption portion cholesterol and change it into depickling salt is discharged in body simultaneously.
5, strengthen immunologic function, lactic acid bacteria is the phagocytosis of activating macrophage obviously, can field planting in enteron aisle, be equivalent to active immunity.
Vitamin C
Vitamin C participates in amino acid metabolism, and nerve is passed former synthetic, and is former synthetic between collagen and histocyte, can reduce capillary permeability, reduce blood fat, increase the ability of the disease of resisting, and certain function of detoxification and the antihistamine effect of tool.
Description of drawings:
The present invention will be further described below in conjunction with accompanying drawing;
Fig. 1 is a process chart of the present invention;
The specific embodiment:
The present invention is by isoflavones, Oilgosaccharkdes, lactein and vitamin C are made through processing, its content by weight percentage: isoflavones 65-80%, Oilgosaccharkdes 10-25%, lactein 9-12%, vitamin C 1-2%.
Embodiment 1:
The present invention is made through processing by isoflavones 65%, Oilgosaccharkdes 25%, lactein 9%, vitamin C 1% (its content by weight percentage).
Embodiment 2:
The present invention is made through processing by isoflavones 70%, Oilgosaccharkdes 20%, lactein 9%, vitamin C 1% (its content by weight percentage).
Embodiment 3:
The present invention is made through processing by isoflavones 75%, Oilgosaccharkdes 12%, lactein 12%, vitamin C 1% (its content by weight percentage).
The present invention makes by the following method:
1, raw material is handled: the soybean meal powder of gained after the soybean degreasing is broken, grain warp is that 0.5mm-0.8mm is standby;
2, solvent extraction: adopt ethanol water to extract, concentration of alcohol is 40%-80%, and solvent and raw material are pressed (8-16): 1 (volume ml/ weight g) puts continuous flow upstream, immerses in the jar, extracts 50 ℃-90 ℃ of temperature, and extraction time is 3 times, extraction time 3h-10h;
3, separate: filter leachate, reclaim ethanol, leave standstill make precipitation fully after, carry out centrifugation, dry sediment, it is standby promptly to get the isoflavones meal;
4, lactic acid bacteria culture medium: beef extract: peptone: multitudinous sugar: sodium chloride: calcium carbonate=0.5%: 2.5%: 2%: 0.5%: 1% charge ratio feeds intake;
5, inoculation, cultivation: the sucrose solution and the good big bottle liquid medium of lactobacter growth that will be cooled to below 40 ℃ are successively all poured in the jar, close immediately after the batching hole sterilization, stir 15 fens kinds, 35 ℃-37 ℃ leave standstill cultivation, stirred 10 minutes in per 2 hours, and cultivated and got zymotic fluid in 10-16 hour;
6, filter: get calcium carbonate and distilled water furnishing pasty state, become filtering layer in the impouring nutsch filter, pour zymotic fluid, suction filtration into, make filter cake, it is standby promptly to get dry powder of lactic acid bacteria after drying, the pulverizing;
7, mix: take by weighing isoflavones powder, lactic acid bacteria powder, vitamin C, Oilgosaccharkdes respectively according to prescribed dose and mix with progressively dilution method and lactic acid bacteria cake, cross 80 mesh sieves through chemically examine qualified after filling.
Claims (3)
1, a kind of additional human body estrogen and the food of regulating gut flora is characterized in that being made through processing by isoflavones, Oilgosaccharkdes, lactein and vitamin C.
2, according to claims 1 described a kind of additional human body estrogen and the food of regulating gut flora, it is characterized in that its content by weight percentage: isoflavones 65-80%, Oilgosaccharkdes 10-25%, lactein 9-12%, vitamin C 1-2%.
3, the preparation method of the food of a kind of additional human body estrogen and adjusting gut flora, make by the following method:
(1), raw material is handled: the soybean meal powder of gained after the soybean degreasing is broken, grain warp is that 0.5mm-0.8mm is standby;
(2), solvent extraction: adopt ethanol water to extract, concentration of alcohol is 40%-80%, and solvent and raw material are pressed (8-16): 1 (volume ml/ weight g) puts continuous flow upstream, immerse in the jar, extract 50 ℃-90 ℃ of temperature, extraction time is 3 times, extraction time 3h-10h;
(3), separate: filter leachate, reclaim ethanol, leave standstill make precipitation fully after, carry out centrifugation, dry sediment, it is standby promptly to get the isoflavones meal;
(4), lactic acid bacteria culture medium: beef extract: peptone: multitudinous sugar: sodium chloride: calcium carbonate=0.5%: 2.5%: 2%: 0.5%: 1% charge ratio feeds intake;
(5), inoculation, cultivation: the sucrose solution and the good big bottle liquid medium of lactobacter growth that will be cooled to below 40 ℃ are successively all poured in the jar, close immediately after the batching hole sterilization, stir 15 fens kinds, 35 ℃-37 ℃ leave standstill cultivation, stirred 10 minutes in per 2 hours, and cultivated and got zymotic fluid in 10-16 hour;
(6), filter: get calcium carbonate and distilled water furnishing pasty state, become filtering layer in the impouring nutsch filter, pour zymotic fluid, suction filtration into, make filter cake, it is standby promptly to get dry powder of lactic acid bacteria after drying, the pulverizing;
(7), mix: take by weighing isoflavones powder, lactic acid bacteria powder, vitamin C, Oilgosaccharkdes respectively according to prescribed dose and mix with progressively dilution method and lactic acid bacteria cake, cross 80 mesh sieves through chemically examine qualified after filling.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100100970A CN1294846C (en) | 2004-03-02 | 2004-03-02 | Food for supplementing estrogen to human body and regulating intenstinal bacilli, and its prepn. method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100100970A CN1294846C (en) | 2004-03-02 | 2004-03-02 | Food for supplementing estrogen to human body and regulating intenstinal bacilli, and its prepn. method |
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| Publication Number | Publication Date |
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| CN1559287A true CN1559287A (en) | 2005-01-05 |
| CN1294846C CN1294846C (en) | 2007-01-17 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102334712A (en) * | 2011-08-25 | 2012-02-01 | 罗四维 | Preparation method of solution for improving enteric microorganisms |
| CN102342414A (en) * | 2011-10-10 | 2012-02-08 | 武汉东方天琪生物工程有限公司 | Nutritional supplement for regulating endocrine based on gastrointestinal tract function improvement and preparation method thereof |
| WO2013053075A1 (en) * | 2011-10-10 | 2013-04-18 | Huang Daiyong | Nutritional supplement for endocrine modulation on the basis of gastrointestinal tract function improvement and preparation method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273838A (en) * | 2000-04-26 | 2000-11-22 | 济南三株药业有限公司 | Nutritive composition containing symbiotic fermentation culture medium of dead probiotics |
-
2004
- 2004-03-02 CN CNB2004100100970A patent/CN1294846C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102334712A (en) * | 2011-08-25 | 2012-02-01 | 罗四维 | Preparation method of solution for improving enteric microorganisms |
| CN102334712B (en) * | 2011-08-25 | 2015-07-01 | 罗四维 | Preparation method of solution for improving enteric microorganisms |
| CN102342414A (en) * | 2011-10-10 | 2012-02-08 | 武汉东方天琪生物工程有限公司 | Nutritional supplement for regulating endocrine based on gastrointestinal tract function improvement and preparation method thereof |
| WO2013053075A1 (en) * | 2011-10-10 | 2013-04-18 | Huang Daiyong | Nutritional supplement for endocrine modulation on the basis of gastrointestinal tract function improvement and preparation method |
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| Publication number | Publication date |
|---|---|
| CN1294846C (en) | 2007-01-17 |
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Granted publication date: 20070117 Termination date: 20140302 |