CN1535318B - 四链体dna和双链体探针系统 - Google Patents

四链体dna和双链体探针系统 Download PDF

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Publication number
CN1535318B
CN1535318B CN01817230XA CN01817230A CN1535318B CN 1535318 B CN1535318 B CN 1535318B CN 01817230X A CN01817230X A CN 01817230XA CN 01817230 A CN01817230 A CN 01817230A CN 1535318 B CN1535318 B CN 1535318B
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chain
body structure
sequence
target
multichain body
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CN1535318A (zh
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亚斯曼·I·戴克斯
格伦·H·埃里克森
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Ingeneus Corp
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6839Triple helix formation or other higher order conformations in hybridisation assays

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
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  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN01817230XA 2000-09-19 2001-09-10 四链体dna和双链体探针系统 Expired - Fee Related CN1535318B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/664,827 US6900300B1 (en) 2000-09-19 2000-09-19 Quadruplex DNA and duplex probe systems
US09/664,827 2000-09-19
PCT/IB2001/001643 WO2002024946A2 (en) 2000-09-19 2001-09-10 Quadruplex dna and duplex probe systems

Publications (2)

Publication Number Publication Date
CN1535318A CN1535318A (zh) 2004-10-06
CN1535318B true CN1535318B (zh) 2010-10-06

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CN01817230XA Expired - Fee Related CN1535318B (zh) 2000-09-19 2001-09-10 四链体dna和双链体探针系统

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US (1) US6900300B1 (enExample)
EP (1) EP1319088A2 (enExample)
JP (1) JP2004520815A (enExample)
CN (1) CN1535318B (enExample)
AU (1) AU2001284350A1 (enExample)
CA (1) CA2422518A1 (enExample)
WO (1) WO2002024946A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656692B2 (en) * 1999-12-21 2003-12-02 Ingeneus Corporation Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
US6927027B2 (en) * 1999-12-21 2005-08-09 Ingeneus Corporation Nucleic acid multiplex formation
WO2004095937A1 (en) 2003-04-28 2004-11-11 Kraft Foods R & D, Inc. Coffee and creamer compositions
BRPI0508100A (pt) * 2004-02-28 2007-07-17 Chang Ning J Wang complexos de ácido nucléico bem como processo para detecção e sistema multifásico
JP2008514197A (ja) 2004-09-24 2008-05-08 インジェネウス インコーポレイテッド ゲノムアッセイ
EP1880019A1 (en) * 2005-05-12 2008-01-23 Arizona Board Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University Self-assembled nucleic acid nanoarrays and uses therefor
KR100833492B1 (ko) * 2005-12-08 2008-05-29 한국전자통신연구원 핵산 나노구조체 및 그의 제조 방법
EP3416976A2 (en) * 2016-02-16 2018-12-26 Yale University Compositions for enhancing targeted gene editing and methods of use thereof
CA2954115C (en) * 2016-10-16 2022-04-12 Neil Gordon Ultra-sensitive bioanalyte quantification from self-assembled quadruplex tags
US11248257B2 (en) * 2017-08-25 2022-02-15 Zoetis Services Llc Method of immobilizing a nucleic acid probe to a solid support
CN109097491B (zh) * 2018-07-26 2021-11-19 湘潭大学 一种基于检测hiv基因的荧光探针
CN109266783B (zh) * 2018-07-27 2022-07-22 广东海洋大学 一种分子信标-g四链体光学传感器及其在检测sv40病毒中的应用
CN117925782B (zh) * 2024-01-16 2024-12-20 深圳吉因加医学检验实验室 一种用于核酸杂交的组合物及其应用

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2000043543A1 (en) * 1999-01-19 2000-07-27 Dade Behring Inc. Detection of differences between polynucleotides

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US5874555A (en) 1987-10-30 1999-02-23 California Institute Of Technology Triple helices and processes for making same
US5451502A (en) * 1990-05-04 1995-09-19 Oncor, Inc. Restriction amplification assay
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
SE506700C2 (sv) 1996-05-31 1998-02-02 Mikael Kubista Sond och förfaranden för analys av nukleinsyra
US5948897A (en) * 1996-06-14 1999-09-07 Simon Fraser University Method of binding two or more DNA double helices and products formed
US5912332A (en) 1996-07-26 1999-06-15 Hybridon, Inc. Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides
US5691145A (en) 1996-08-27 1997-11-25 Becton, Dickinson And Company Detection of nucleic acids using G-quartets
US6312925B1 (en) 1997-05-08 2001-11-06 Epoch Pharmaceuticals, Inc. Methods and compositions to facilitate D-loop formation by oligonucleotides
GB9725197D0 (en) 1997-11-29 1998-01-28 Secr Defence Detection system
US6287772B1 (en) 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
US6017709A (en) 1998-04-29 2000-01-25 University Of Houston DNA replication templates stabilized by guanine quartets
US6255469B1 (en) 1998-05-06 2001-07-03 New York University Periodic two and three dimensional nucleic acid structures
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
GB9821989D0 (en) 1998-10-08 1998-12-02 Hybaid Ltd Detection of nucleic acid polymorphism
US6420115B1 (en) * 1999-12-21 2002-07-16 Ingeneus Corporation Cation mediated triplex hybridization assay

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043543A1 (en) * 1999-01-19 2000-07-27 Dade Behring Inc. Detection of differences between polynucleotides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
作者:.标题:A unique four-stranded model of a homologous recombinationintermediate..Journal of theoretical biology卷号:120 期号:2.1986,120(2),215-222.
作者:.标题:A unique four-stranded model of a homologous recombinationintermediate..Journal of theoretical biology卷号:120 期号:2.1986,120(2),215-222. *
作者:.标题:Four strand recombination model.Journal of theoretical biology卷号:136 期号:2.1989,136(2),135-150.
作者:.标题:Four strand recombination model.Journal of theoretical biology卷号:136 期号:2.1989,136(2),135-150. *

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Publication number Publication date
EP1319088A2 (en) 2003-06-18
AU2001284350A1 (en) 2002-04-02
WO2002024946A2 (en) 2002-03-28
JP2004520815A (ja) 2004-07-15
CN1535318A (zh) 2004-10-06
WO2002024946A3 (en) 2003-03-13
CA2422518A1 (en) 2002-03-28
US6900300B1 (en) 2005-05-31

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