CA2422518A1 - Quadruplex dna and duplex probe systems - Google Patents
Quadruplex dna and duplex probe systems Download PDFInfo
- Publication number
- CA2422518A1 CA2422518A1 CA002422518A CA2422518A CA2422518A1 CA 2422518 A1 CA2422518 A1 CA 2422518A1 CA 002422518 A CA002422518 A CA 002422518A CA 2422518 A CA2422518 A CA 2422518A CA 2422518 A1 CA2422518 A1 CA 2422518A1
- Authority
- CA
- Canada
- Prior art keywords
- strand
- multiplex structure
- target
- probe
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- RJURFGZVJUQBHK-IIXSONLDSA-N actinomycin D Chemical compound C[C@H]1OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@@H](C(C)C)NC(=O)[C@H]1NC(=O)C1=C(N)C(=O)C(C)=C2OC(C(C)=CC=C3C(=O)N[C@@H]4C(=O)N[C@@H](C(N5CCC[C@H]5C(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)O[C@@H]4C)=O)C(C)C)=C3N=C21 RJURFGZVJUQBHK-IIXSONLDSA-N 0.000 description 1
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- MLMVLVJMKDPYBM-UHFFFAOYSA-N pseudoisopsoralene Natural products C1=C2C=COC2=C2OC(=O)C=CC2=C1 MLMVLVJMKDPYBM-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/664,827 | 2000-09-19 | ||
| US09/664,827 US6900300B1 (en) | 2000-09-19 | 2000-09-19 | Quadruplex DNA and duplex probe systems |
| PCT/IB2001/001643 WO2002024946A2 (en) | 2000-09-19 | 2001-09-10 | Quadruplex dna and duplex probe systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2422518A1 true CA2422518A1 (en) | 2002-03-28 |
Family
ID=24667604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002422518A Abandoned CA2422518A1 (en) | 2000-09-19 | 2001-09-10 | Quadruplex dna and duplex probe systems |
Country Status (7)
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| EP (1) | EP1319088A2 (enExample) |
| JP (1) | JP2004520815A (enExample) |
| CN (1) | CN1535318B (enExample) |
| AU (1) | AU2001284350A1 (enExample) |
| CA (1) | CA2422518A1 (enExample) |
| WO (1) | WO2002024946A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6656692B2 (en) * | 1999-12-21 | 2003-12-02 | Ingeneus Corporation | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
| US6927027B2 (en) * | 1999-12-21 | 2005-08-09 | Ingeneus Corporation | Nucleic acid multiplex formation |
| WO2004095937A1 (en) | 2003-04-28 | 2004-11-11 | Kraft Foods R & D, Inc. | Coffee and creamer compositions |
| CA2557661A1 (en) * | 2004-02-28 | 2005-09-15 | Chang-Ning J. Wang | Nucleic acid complexes |
| US8486622B2 (en) | 2004-09-24 | 2013-07-16 | Ingeneus Inc. | Genomic assay |
| WO2006124089A1 (en) * | 2005-05-12 | 2006-11-23 | The Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University | Self-assembled nucleic acid nanoarrays and uses therefor |
| KR100833492B1 (ko) * | 2005-12-08 | 2008-05-29 | 한국전자통신연구원 | 핵산 나노구조체 및 그의 제조 방법 |
| CN109476706A (zh) * | 2016-02-16 | 2019-03-15 | 耶鲁大学 | 用于促进靶向基因编辑的组合物及其使用方法 |
| CA2954115C (en) * | 2016-10-16 | 2022-04-12 | Neil Gordon | Ultra-sensitive bioanalyte quantification from self-assembled quadruplex tags |
| US11248257B2 (en) * | 2017-08-25 | 2022-02-15 | Zoetis Services Llc | Method of immobilizing a nucleic acid probe to a solid support |
| CN109097491B (zh) * | 2018-07-26 | 2021-11-19 | 湘潭大学 | 一种基于检测hiv基因的荧光探针 |
| CN109266783B (zh) * | 2018-07-27 | 2022-07-22 | 广东海洋大学 | 一种分子信标-g四链体光学传感器及其在检测sv40病毒中的应用 |
| CN117925782B (zh) * | 2024-01-16 | 2024-12-20 | 深圳吉因加医学检验实验室 | 一种用于核酸杂交的组合物及其应用 |
Family Cites Families (16)
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| US5874555A (en) | 1987-10-30 | 1999-02-23 | California Institute Of Technology | Triple helices and processes for making same |
| US5451502A (en) * | 1990-05-04 | 1995-09-19 | Oncor, Inc. | Restriction amplification assay |
| US5424413A (en) * | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| SE506700C2 (sv) | 1996-05-31 | 1998-02-02 | Mikael Kubista | Sond och förfaranden för analys av nukleinsyra |
| US5948897A (en) * | 1996-06-14 | 1999-09-07 | Simon Fraser University | Method of binding two or more DNA double helices and products formed |
| US5912332A (en) | 1996-07-26 | 1999-06-15 | Hybridon, Inc. | Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides |
| US5691145A (en) | 1996-08-27 | 1997-11-25 | Becton, Dickinson And Company | Detection of nucleic acids using G-quartets |
| US6312925B1 (en) | 1997-05-08 | 2001-11-06 | Epoch Pharmaceuticals, Inc. | Methods and compositions to facilitate D-loop formation by oligonucleotides |
| GB9725197D0 (en) | 1997-11-29 | 1998-01-28 | Secr Defence | Detection system |
| US6017709A (en) | 1998-04-29 | 2000-01-25 | University Of Houston | DNA replication templates stabilized by guanine quartets |
| US6287772B1 (en) | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
| US6255469B1 (en) | 1998-05-06 | 2001-07-03 | New York University | Periodic two and three dimensional nucleic acid structures |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| GB9821989D0 (en) | 1998-10-08 | 1998-12-02 | Hybaid Ltd | Detection of nucleic acid polymorphism |
| US6420115B1 (en) * | 1999-12-21 | 2002-07-16 | Ingeneus Corporation | Cation mediated triplex hybridization assay |
| WO2000043543A1 (en) | 1999-01-19 | 2000-07-27 | Dade Behring Inc. | Detection of differences between polynucleotides |
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2000
- 2000-09-19 US US09/664,827 patent/US6900300B1/en not_active Expired - Fee Related
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2001
- 2001-09-10 CA CA002422518A patent/CA2422518A1/en not_active Abandoned
- 2001-09-10 EP EP01963329A patent/EP1319088A2/en not_active Withdrawn
- 2001-09-10 CN CN01817230XA patent/CN1535318B/zh not_active Expired - Fee Related
- 2001-09-10 WO PCT/IB2001/001643 patent/WO2002024946A2/en not_active Ceased
- 2001-09-10 JP JP2002529538A patent/JP2004520815A/ja active Pending
- 2001-09-10 AU AU2001284350A patent/AU2001284350A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1535318A (zh) | 2004-10-06 |
| JP2004520815A (ja) | 2004-07-15 |
| WO2002024946A2 (en) | 2002-03-28 |
| EP1319088A2 (en) | 2003-06-18 |
| WO2002024946A3 (en) | 2003-03-13 |
| CN1535318B (zh) | 2010-10-06 |
| AU2001284350A1 (en) | 2002-04-02 |
| US6900300B1 (en) | 2005-05-31 |
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