CN1528339A - Chitin soft capsule and preparing method thereof - Google Patents
Chitin soft capsule and preparing method thereof Download PDFInfo
- Publication number
- CN1528339A CN1528339A CNA2003101193338A CN200310119333A CN1528339A CN 1528339 A CN1528339 A CN 1528339A CN A2003101193338 A CNA2003101193338 A CN A2003101193338A CN 200310119333 A CN200310119333 A CN 200310119333A CN 1528339 A CN1528339 A CN 1528339A
- Authority
- CN
- China
- Prior art keywords
- parts
- soft capsule
- weight portion
- chitin
- chitosan powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The present invention discloses a health-care medicine chitin soft capsule, and its composition includes chitosan powder, soya lecithin, vitamin E and vegetable oil. Its preparation method includes the following steps: A. using superfine pulverization equipment to make the chitosan powder into fine powder granules with 100-200 meshes; B. using (by weight portion) 18-25 portions of chitosan powder, 2-8 portions of soya lecithin, 1-4 portions of vitamin E and 75-85 portions of vegetable oil, and adding emulsifier, and stirring them to obtain mixed suspension; C. feeding said mixed suspension into colloid mill, fine milling and filtering to obtain mud-like colloid; D. feeding said colloid material into pill-making machine to make pill at a certain temp.; and E. making defatting treatment so as to obtain the invented soft capsule product with several health-care functions of reducing blood fat, reducing blood sugar, raising immunity, resisting cancers, resisting senility and protecting liver, etc.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hyperlipidemia, diabetes, hypertension, inhibition neoplasm metastasis, specifically a kind of chitin soft capsule and preparation method thereof.
Background technology
At present, along with improving constantly of people's living standard, dietary structure changes, and hyperlipidemia, hypercholesterolemia and Simple Obesity patient are increasing, so that causes cardiovascular and cerebrovascular disease to rise to first serious disease of harm humans health.Operating pressure is big, and rhythm of life is fast, and living environment is polluted, and causes sickness rate such as hypertension, diabetes, tumor to increase day by day.Researcher is day and night tackled key problems for these diseases of treatment both at home and abroad.People are through discovering, at the ocean water product,, can extract a kind of material that is chitin sugar in the garbage after the processing (Carapax Eriocheir sinensis) as Portunustrituberculatus, it has the fancy effect of transferring blood fat, suppressing tumor growth, thereby be widely used in producing health food, but because its composition is single, mouthfeel is not good, be difficult to promote, to its Pharmacological action study with utilize and also not make a breakthrough, make this both favourable environmental protection, the medicine that helps human health again fails to be fully used.
Summary of the invention
The purpose of this invention is to provide a kind of chitin that extracts from sea leave is primary raw material, adds to make a kind of novel, collection health care behind an amount of composition and medicine is novel chitin soft capsule of one and preparation method thereof.
Technical scheme of the present invention is:
A kind of chitin soft capsule is characterized in that comprising chitosan powder, soybean phospholipid, vitamin E, vegetable oil.
The proportion of composing of each Main Ingredients and Appearance is in the chitin soft capsule composition of the present invention: the weight portion of chitosan powder is that 18～25 parts, the weight portion of soybean phospholipid are that 2～8 parts, the weight portion of vitamin E are that 1～4 part, the weight portion of vegetable oil are 25～85 parts.The weight portion that its best proportioning is a chitosan powder is that 20 parts, the weight portion of soybean phospholipid are that 2 parts, the weight portion of vitamin E are that 1 part, the weight portion of vegetable oil are 77 parts.
Chitin preparation of soft capsule method of the present invention is:
A, chitosan powder become 100～200 fine particle with the micropowder apparatus processing;
B, get 18～25 parts of chitosan powder weight portions, 2～8 parts of soybean phospholipid weight portions, 1～4 part of vitamin E weight portion, 75～85 parts of vegetable oil weight portions, add emulsifier for mixing and become suspension;
C, suspension sent in the colloid mill filter after the fine grinding, obtain mud shape gel;
D, mud shape gel sent into carries out the constant temperature pill in the pellet processing machine, soft gelatin capsule;
E, obtain soft capsule, soft capsule is sent in the drying machine obtained finished product through redrying with carrying out ungrease treatment after the soft gelatin capsule typing.
The temperature of above-mentioned constant temperature pill is 40～80 degree.The temperature control of redrying once is 40～60 degree, is for the second time 40～60 degree.
Chitin soft capsule of the present invention also can be made into hard capsule, and hard capsule is meant the capsule that only comprises chitosan powder.
Beneficial effect of the present invention:
1, the main effective component chitin content with the chitin soft capsule of the equal specification of manufacturing of the present invention is 100～110mg (milligram), obviously higher than external like product (only containing 70～75mg chitin), but also soybean phospholipid and vitamin E have been added, formed compound product, its effective component is more comprehensive, and effect is better in transferring diseases such as fat, blood fat reducing, arteriosclerosis.
2, the present invention has blood fat reducing, blood sugar lowering, adjusting pH value of body, improves the effect of acidic physique.Also have different physiological roles such as blood lipid regulation, softening cardiovascular and cerebrovascular vessel, raise immunity, anticancer, anti-aging, antiinflammatory, hepatoprotective simultaneously.Both can be used as health product and used, also can be used as the medicine for treatment thing, had anosis diseases prevention, ill special efficacy of curing the disease.
3, the present invention have easy absorption, nontoxic, have no side effect, it is better to take effect for a long time.
4, through the Jiangsu Prov. People's Hospital, the prison bed checking of Jiangsu TCM Hospital, Nanjing Chinese Medicine Hospital, the blood fat reducing total effective rate is 78.5%, clinical response is good.
5, inhibited to tumor neogenetic blood vessels, organ pipes such as bone marrow, gastrointestinal tract, hair there is not toxicity, can not produce drug resistance.
6, technology is simple, the raw material wide material sources, and useful to the protection environment, can reduce the pollution of sea leave to environment.
7, market prospect is wide, small investment, instant effect.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment.
Embodiment one.
A, chitosan powder is become 120 purpose fine particles with the micropowder apparatus processing;
B, get 20 parts of chitosan powder weight portions, 2 parts of soybean phospholipid weight portions, 1 part of vitamin E weight portion, 77 parts of vegetable oil weight portions, add emulsifier for mixing and become suspension;
C, suspension sent in the colloid mill filter after the fine grinding, obtain mud shape gel;
D, mud shape gel sent into when 60 spend, carry out the constant temperature pill in the pellet processing machine, obtain soft gelatin capsule;
E, obtain soft capsule, soft capsule is sent in the drying machine under 40 degree, carried out primary drying, and then under 50 degree, carry out redrying and obtain finished product carrying out ungrease treatment after the soft gelatin capsule typing.
Embodiment two.
A, chitosan powder is become 100 purpose fine particles with the micropowder apparatus processing;
B, get 18 parts of chitosan powder weight portions, 2 parts of soybean phospholipid weight portions, 1 part of vitamin E weight portion, 75 parts of vegetable oil weight portions, add emulsifier for mixing and become suspension;
C, suspension sent in the colloid mill filter after the fine grinding, obtain mud shape gel;
D, mud shape gel sent into when 40 spend, carry out the constant temperature pill in the pellet processing machine, obtain soft gelatin capsule;
E, obtain soft capsule, soft capsule is sent into carried out 40 degree primary dryings in the drying machine respectively and 40 degree redryings obtain finished product carrying out ungrease treatment after the soft gelatin capsule typing.
Embodiment three.
A, chitosan powder is become 200 purpose fine particles with the micropowder apparatus processing;
B, get 25 parts of chitosan powder weight portions, 8 parts of soybean phospholipid weight portions, 4 parts of vitamin E weight portions, 85 parts of vegetable oil weight portions, add emulsifier for mixing and become suspension;
C, suspension sent in the colloid mill filter after the fine grinding, obtain mud shape gel;
D, mud shape gel sent into when 80 spend, carry out the constant temperature pill in the pellet processing machine, obtain soft gelatin capsule;
E, obtain soft capsule, soft capsule is sent into carried out 60 degree primary dryings in the drying machine and 60 degree redryings obtain finished product carrying out ungrease treatment after the soft gelatin capsule typing.
Claims (6)
1, a kind of chitin soft capsule is characterized in that comprising chitosan powder, soybean phospholipid, vitamin E, vegetable oil.
2, according to claim 1 is described the chitin soft capsule arranged, the weight portion that it is characterized in that chitosan powder is that 18～25 parts, the weight portion of soybean phospholipid are that 2～8 parts, the weight portion of vitamin E are that 1～4 part, the weight portion of vegetable oil are 25～85 parts.
3, according to claim 1 is described the chitin soft capsule arranged, the weight portion that it is characterized in that chitosan powder is that 20 parts, the weight portion of soybean phospholipid are that 2 parts, the weight portion of vitamin E are that 1 part, the weight portion of vegetable oil are 77 parts.
4, a kind of chitin preparation of soft capsule method is characterized in that:
A, chitosan powder become 100～200 fine particle with the micropowder apparatus processing;
B, get 18～25 parts of chitosan powder weight portions, 2～8 parts of soybean phospholipid weight portions, 1～4 part of vitamin E weight portion, 75～85 parts of vegetable oil weight portions, add emulsifier for mixing and become suspension;
C, suspension sent in the colloid mill filter after the fine grinding, obtain mud shape gel;
D, mud shape gel sent into carries out the constant temperature pill in the pellet processing machine, soft gelatin capsule;
E, obtain soft capsule, soft capsule is sent in the drying machine obtained finished product through redrying with carrying out ungrease treatment after the soft gelatin capsule typing.
5, chitin preparation of soft capsule method according to claim 4, the temperature that it is characterized in that the constant temperature pill are 40～80 degree.
6, chitin preparation of soft capsule method according to claim 4, the temperature control that it is characterized in that redrying once are 40～60 degree, are for the second time 40～60 degree.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310119333 CN1235595C (en) | 2003-10-20 | 2003-12-05 | Chitin soft capsule and preparing method thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200310106158.9 | 2003-10-20 | ||
| CN200310106158 | 2003-10-20 | ||
| CN 200310119333 CN1235595C (en) | 2003-10-20 | 2003-12-05 | Chitin soft capsule and preparing method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1528339A true CN1528339A (en) | 2004-09-15 |
| CN1235595C CN1235595C (en) | 2006-01-11 |
Family
ID=34314859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200310119333 Expired - Fee Related CN1235595C (en) | 2003-10-20 | 2003-12-05 | Chitin soft capsule and preparing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1235595C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008068763A2 (en) * | 2006-12-07 | 2008-06-12 | Ben-Bar Technology 2006 Ltd. | Mixture and method for reducing cholesterol using hydrophobic chitosan microparticles |
| CN100450493C (en) * | 2005-02-07 | 2009-01-14 | 陈福存 | Black fungus composite soft capsule and its preparing process |
| CN102125203A (en) * | 2010-12-23 | 2011-07-20 | 宁波普爱生物工程有限公司 | Glycosaminoglycan ultrafine particle-containing health food and production method thereof |
| CN102763843A (en) * | 2012-07-05 | 2012-11-07 | 昆明豪原特自控有限公司 | Biological nutrient |
| CN112674344A (en) * | 2021-01-21 | 2021-04-20 | 江苏曼氏生物科技股份有限公司 | Phospholipid granule and preparation method thereof |
-
2003
- 2003-12-05 CN CN 200310119333 patent/CN1235595C/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100450493C (en) * | 2005-02-07 | 2009-01-14 | 陈福存 | Black fungus composite soft capsule and its preparing process |
| WO2008068763A2 (en) * | 2006-12-07 | 2008-06-12 | Ben-Bar Technology 2006 Ltd. | Mixture and method for reducing cholesterol using hydrophobic chitosan microparticles |
| WO2008068763A3 (en) * | 2006-12-07 | 2008-07-24 | Ben Bar Technology 2006 | Mixture and method for reducing cholesterol using hydrophobic chitosan microparticles |
| CN102125203A (en) * | 2010-12-23 | 2011-07-20 | 宁波普爱生物工程有限公司 | Glycosaminoglycan ultrafine particle-containing health food and production method thereof |
| CN102125203B (en) * | 2010-12-23 | 2013-07-31 | 宁波普爱生物工程有限公司 | Glycosaminoglycan ultrafine particle-containing health food and production method thereof |
| CN102763843A (en) * | 2012-07-05 | 2012-11-07 | 昆明豪原特自控有限公司 | Biological nutrient |
| CN112674344A (en) * | 2021-01-21 | 2021-04-20 | 江苏曼氏生物科技股份有限公司 | Phospholipid granule and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1235595C (en) | 2006-01-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105105116A (en) | Health food with effects of relieving physical fatigue and enhancing immunity and preparation method of health food | |
| CN1939296A (en) | Theapolyphenol composition and its preparation | |
| JP2007181447A (en) | Buckwheat noodle enriched in ingredient and method for producing the same | |
| CN1640488A (en) | Method for preparing supermicro powder preparation of cordyceps sinensis mycelium | |
| CN1235595C (en) | Chitin soft capsule and preparing method thereof | |
| CN101066402A (en) | Chineses medicine prepn with several treating functions and its prepn proces and application | |
| CN111228238B (en) | Pharmaceutical composition containing orlistat and oligosaccharide | |
| CN101427778A (en) | Health care instant noodles and method of producing the same | |
| CN1606917A (en) | Method for extracting lactalbumin and separating different active ingredient of lactalbumin | |
| CN105410941A (en) | Serene Tablet health-care food capable of increasing bone density and strengthening immunity and preparation method thereof | |
| CN1272025C (en) | Solid fermented fungus powder as food and medicine | |
| CN103800290A (en) | Glucosamine hydrochloride pellet preparation and preparation method thereof | |
| CN1586297A (en) | Body building health preparation and its producing method | |
| CN108552525B (en) | Lipid-lowering weight-losing functional food | |
| CN100345534C (en) | Yinzhi huang capsule, its preparation method and use | |
| CN101120778A (en) | Natto biological acid preparation | |
| CN1535708A (en) | Oral aerosol for reducing or eliminating snore and its preparation method | |
| CN1081464C (en) | Chinese medicine for acute and chronic diarrhea, dysentery with purulent and bloody stools, as well as acute and chronic colitis | |
| CN1814116A (en) | Chinese medicine for treating gastric cavity ache and preparing method | |
| CN101073652A (en) | Chinese-medicinal pillow for treating chronic effort syndrome and its production | |
| CN1277553C (en) | Redy preparation Chinese medicine for treating kinetic fatigue and chronic fatigue syndrome | |
| CN1415309A (en) | Nano selenium of Melatonin and its preparation method | |
| CN1189373A (en) | Medicinal wine for treating cancer | |
| CN1172692C (en) | Powdered medicine for treating tumor and its preparing process | |
| CN104544113A (en) | Buccal tablets containing walnuts |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: YIN XIUZHI Free format text: FORMER OWNER: JINLING YIN S HEALTH PRODUCTS CO., LTD., NANJING Effective date: 20050909 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20050909 Address after: 210009 room 3, building 7, No. two, 303 bridge tower, three steps, Gulou District, Jiangsu, Nanjing Applicant after: Yin Xiuzhi Address before: 210011 Shuanglong road 185, Jiangning District, Jiangsu, Nanjing Applicant before: Jinling Yin's Health Products Co., Ltd., Nanjing |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060111 Termination date: 20100105 |