CN1522743A - Kidney disease therapeutic pharmaceutical - Google Patents

Kidney disease therapeutic pharmaceutical Download PDF

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Publication number
CN1522743A
CN1522743A CNA031509436A CN03150943A CN1522743A CN 1522743 A CN1522743 A CN 1522743A CN A031509436 A CNA031509436 A CN A031509436A CN 03150943 A CN03150943 A CN 03150943A CN 1522743 A CN1522743 A CN 1522743A
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China
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medicine
treatment
nephropathy
radix
kidney
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Pending
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CNA031509436A
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Chinese (zh)
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群 顾
顾群
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Individual
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Individual
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Priority to CNA031509436A priority Critical patent/CN1522743A/en
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Abstract

The present invention relates to a medicine with the functions of supplementing qi, securing kidney, promoting blood circulation to remove stasis, clearing heat, disinhibiting dampness, regulating and supplementing spleen and kidney and regulating yin and yang in treating acute and chronic nephritis, chronic glomerulonephritis, chronic pyelonephritis and latent nephritis. Said medicine is prepared by making 8 Chinese medicinal materials of astragalus root, ginseng, cornux fruit, imperata root, phellodendron bark, smooth greenbrier root and others go through the processes of low-temp. drying, grinding and capsulizing. Its therapeutic effect is reliable, and its cure rate is above 95.2%.

Description

A kind of medicine for the treatment of nephropathy
Technical field
The present invention relates to a kind of medicine for the treatment of nephropathy.
Background technology
The said nephropathy of modern medicine, its reason is a lot, comprise infect to poison, multiple factors such as body's immunity is unusual, metabolism obstacle and heredity, what effect method it does not have yet in treatment.Though and the traditional Chinese medical science does not have all kinds of names of disease of nephropathy; but the performance of a large amount of TCM Document data and record and modern medicine nephropathy is same or similar; the described kidney of theory of Chinese medical science is human body " the congenital foundation ", " root of life "; when human body diseases caused by exogenous pathogenic factor pathogen, patient trauma internal organs, cause qi depression to blood stasis; letting out of kidney is turbid, spleen fortune is hindered to cause that water is wet to stop amassing, and yin and yang imbalance, spleen are suffered from a deficiency of the kidney and lost; two just mistake departments make in the metabolite retention bodies such as serum creatinine, blood urea nitrogen.Its disease has edema, and urine, hematuria certainly, also have lumbago, weak, glucose in urine blood glucose increases and other poisoning symptoms, direct threat to life, its sick position is at lung, spleen, kidney.At present nephropathy also there is not special effect medicine therapeutic as yet.
Summary of the invention
The medicine of the treatment nephropathy that purpose of the present invention just provides a kind of good effect, has no side effect, pure Chinese herbal medicine is made.
The medicine of treatment nephropathy of the present invention is made up of following weight portion raw material:
Radix Astragali 12-18 Radix Ginseng 8-10
Fructus Corni 10-12 Rhizoma Imperatae 18-22
Cortex Phellodendri 15-18 Rhizoma Smilacis Glabrae 14-16
Stamen Nelumbinis 12-15 Radix Notoginseng 8-12
The process for preparing medicine of treatment nephropathy of the present invention is: with the above-mentioned raw materials oven drying at low temperature, and grind into powder afterwards, and be filled in the Capsules, every capsule dose is 4 grams.
The property of medicine of each crude drug in the medicine of treatment nephropathy of the present invention:
Radix Astragali: sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Ginseng: sweet, little hardship, flat.Return spleen, lung, heart channel.Strongly invigorating primordial QI, pulse in summer takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid, and composes oneself.Be used for weak body and prostration, the cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, and prolonged illness is empty wins, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.
Fructus Corni: slightly warm in nature, sour in the mouth, puckery.Liver and kidney tonifying, essence astringing and desertion stemming.Be used for vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.
Rhizoma Imperatae: sweet, cold.Return lung, stomach, urinary bladder channel.Cooling blood for hemostasis, clearing away heat and promoting diuresis.Be used for heat in blood and spit blood epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.
Cortex Phellodendri: hardship, cold.Return kidney, urinary bladder channel.Heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.
Rhizoma Smilacis Glabrae: sweet, light, flat.Return liver, stomach warp.Dehumidifying, detoxifcation, easing joint movement.Be used for damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, the limbs contracture due to the scrofula, scabies, syphilis and mercurialism, bones and muscles pain.
Stamen Nelumbinis: sweet, puckery, flat.GUIXIN, kidney channel.Reinforcing the kindey to control nocturnal emission.Be used for emission and spermatorrhea, leukorrhagia, frequent micturition.
Radix Notoginseng: sweet, little hardship, temperature.Return liver, stomach warp.The dissipating blood stasis hemostasis, subduing swelling and relieving pain.Be used for spitting of blood, spit blood, epistaxis is had blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Rhizoma Imperatae, Cortex Phellodendri energy heat clearing and damp drying, diuresis, antiinflammatory in the medicine of treatment nephropathy of the present invention are so be this medicine monarch drug; Fructus Corni, Stamen Nelumbinis, Radix Astragali, Radix Ginseng play spleen reinforcing and reinforce the kidney, regulate the negative and positive effect, so be this medicine ministerial drug; Radix Notoginseng, Rhizoma Smilacis Glabrae effect are blood circulation promoting and blood stasis dispelling, so be the adjuvant drug of this medicine.
The medicine of treatment nephropathy of the present invention has that QI invigorating is reinforced the kidney, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, transfer the spleen reinforcing kidney, regulate effects such as negative and positive, acute and chronic nephritis, chronic glomerulonephritis, chronic pyelonephritis, latent nephritis etc. all there is significant curative effect, through clinical practice for many years, show determined curative effect, cure rate is more than 95.2%.
The medicine of treatment nephropathy of the present invention is collected outpatient service nephritis 63 examples altogether from year August in March, 1998-2003, male's 47 examples wherein, and women's 16 examples, nephropathy patient's classification and disease are:
The nephrotic syndrome 14 examples account for 22.2%: its clinical manifestation with a large amount of albuminuria (〉=3.5g/24h), (plasma albumin≤3.0g%), hyperlipemia and obvious edema are the syndrome of principal character to hypoproteinemia.
Acute nephritis 20 examples account for 31.6%: its clinical manifestation is mainly edema, hematuria, hypertension, urine protein, and to be generally (+--++) a large amount of albuminuria more rare, most in 2-3 week, transfers to a small amount of.
Chronic nephritis 29 examples account for 46.2%: it is clinical to be feature with albuminuria, hematuria, edema, hypertension and renal insufficiency mainly.Along with PD, the patient renal failure occurs after more than 2-3 or 20-30.
3 kinds of disease patients control by distinguishing disease executing to above 63 examples, take the medicine of treatment nephropathy of the present invention, and this medicament capsule, every capsule dose are 4 grams, and boiled water send down, and every day one to three time, each one, 20-30 days is a course of treatment.
Curative effect judging standard:
1, cure: clinical symptoms all disappears, and routine urinalysis detects albumen, heavy inspection (RBe) is negative, and renal function detects: sanguinin nitrogen (B μ N) at 2.3-7.8mmol/L, creatinine (CYe) in male 53-97mmol/L, women 44-60mmol/L normal value.
2, produce effects: clinical symptoms disappears substantially, and routine urinalysis detects albumen, heavy inspection (RBe) is negative, and renal function detects: sanguinin nitrogen (B μ N) 2.3-7.8mmol/L, creatinine (CYe) male 53-97mmol/L, women 44-60mmol/L near normal value in.
3, take a turn for the better: main clinic symptoms disappears substantially, and routine urinalysis detects albumen, heavy inspection (RBe) transfers feminine gender substantially to, and the renal function check: sanguinin nitrogen (B μ N), creatinine (CYe) be not still in normal value.
4, invalid: and compare before the medication, each side does not all have improvement.
Result of use:
Chronic nephritis Acute nephritis The nephrotic syndrome Add up to
Cure (example) ????16 ????17 ????10 ????33
Produce effects (example) ????4 ????2 ????1 ????7
Take a turn for the better (example) ????7 ????1 ????2 ????10
Invalid (example) ????2 ????0 ????1 ????3
See that more than medicine of the present invention reaches 95.2% to 63 routine nephrotic's effective percentage.
Model case
1, Luo, the man, 41 years old, the tame people suffered from chronic nephritis 6 years, in the diagnosis and treatment of coming on May 31 in 2003, disease see eyelid and edema of lower limbs, weak, pale complexion is simple and unadorned, receive can, there is the tooth seal on the enlarged tongue limit, routine urinalysis detects albumen, heavy inspection is positive.Take the capsule of treatment nephropathy of the present invention, every day three times, each one, after one month, all are normal for routine urinalysis, and clinical symptoms all disappears.
2, Huang, the woman, 29 years old, suffered from the nephrotic syndrome 2 years, in the diagnosis and treatment of coming on May 13 in 2002, its symptom puffiness of the eyes, weak, pale complexion is simple and unadorned, poor appetite, short urination are few, frequent micturition, soreness of waist pain, through chemical examination albumen (+++), Rbe (+), renal function: B μ N14.2mmol/L, Cye 196.8mmol/L.Take the capsule of treatment nephropathy of the present invention, every day three times, each one, after two months, all are normal in every chemical examination, and symptom all disappears, and does not send out so far.
3, Zhang, the man, 36 years old, suffered from the nephrotic syndrome 3 years, in the diagnosis and treatment of coming on the 10th of calendar year 2001 JIUYUE, there are tooth seal, deep pulse in its symptom anasarca, lassitude, weak, the soreness of waist, short urination, frequent micturition, the big limit of corpulent tongue.Through chemical examination albumen (+++), Rbe (+++), renal function: B μ N12mmol/L, Cye214mmol/L.Take the capsule of treatment nephropathy of the present invention, every day three times, each one, after nearly two months, every laboratory indexes is normal, and symptom all disappears, so far not recurrence.
4, surplus so-and-so, the man 20 years old, suffered from acute nephritis 1 month, in the diagnosis and treatment of coming on August 9 in 2003, its symptom anasarca, short urination.Through chemical examination albumen (+).Take the capsule of treatment nephropathy of the present invention, every day secondary, each one, after 20 days, every laboratory indexes is normal, transference cure.
5, pay literary composition, the man, 50 years old, suffered from the nephrotic syndrome 2 years, in the diagnosis and treatment of coming on March 6 in 2003, its disease saw that two slight edema of lower limb, pale complexion, the soreness of waist, short urination, frequent micturition, corpulent tongue are big.Through chemical examination albumen (+++), Rbe (++), renal function: B μ N10.6mmol/L, Cye157mmol/L.Take the capsule of treatment nephropathy of the present invention, every day secondary, each one, nearly two courses of treatment, every laboratory indexes is normal, symptom all disappears.
6, multitude, the man 12 years old, suffered from acute nephritis 1 month, in the diagnosis and treatment of coming on April 20 in 2002, its symptom puffiness of face.Through the albumen (++) that has a routine urine test, Rbe (++).Take the capsule of treatment nephropathy of the present invention, every day secondary, each one, after two courses of treatment, every laboratory indexes is normal, transference cure.
7, Huang, the man 6 years old, suffered from acute nephritis 2 months, in the diagnosis and treatment of coming on January 10 in 2003, its symptom anasarca.Through the albumen that has a routine urine test (+++), Rbe (+).Take the capsule of treatment nephropathy of the present invention, every day secondary, each one, after two courses of treatment, every laboratory indexes is normal, transference cure.
8, Lee so-and-so, the woman 10 years old, suffers from acute nephritis, in the diagnosis and treatment of coming on March 20 in 2003, its symptom anasarca, short urination, frequent micturition.Through the albumen (++) that has a routine urine test, Rbe (+).Take the capsule of treatment nephropathy of the present invention, every day three times, each one, after two courses of treatment, every laboratory indexes is normal, transference cure.
The specific embodiment
Embodiment 1:
A kind of medicine for the treatment of nephropathy is made up of following weight portion raw material:
Radix Astragali 18 gram Radix Ginsengs 8 grams
Fructus Corni 10 gram Rhizoma Imperataes 22 grams
Cortex Phellodendri 15 gram Rhizoma Smilacis Glabraes 14 grams
Stamen Nelumbinis 15 gram Radix Notoginseng 12 grams
The process for preparing medicine of treatment nephropathy of the present invention is: with the above-mentioned raw materials oven drying at low temperature, and grind into powder afterwards, and be filled in the Capsules, every capsule dose is 4 grams.
Embodiment 2:
A kind of medicine for the treatment of nephropathy is made up of following weight portion raw material:
Radix Astragali 15 gram Radix Ginsengs 10 grams
Fructus Corni 10 gram Rhizoma Imperataes 20 grams
Cortex Phellodendri 15 gram Rhizoma Smilacis Glabraes 15 grams
Stamen Nelumbinis 15 gram Radix Notoginseng 10 grams
With the above-mentioned raw materials oven drying at low temperature, grind into powder afterwards, and be filled in the Capsules, every capsule dose is 4 grams.

Claims (3)

1, a kind of medicine for the treatment of nephropathy is characterized in that: it is made up of following weight portion raw material:
Radix Astragali 12-18 Radix Ginseng 8-10
Fructus Corni 10-12 Rhizoma Imperatae 18-22
Cortex Phellodendri 15-18 Rhizoma Smilacis Glabrae 14-16
Stamen Nelumbinis 12-15 Radix Notoginseng 8-12.
2, a kind of medicine for the treatment of nephropathy according to claim 1, it is characterized in that: it is made up of following weight portion raw material:
Radix Astragali 18 Radix Ginsengs 8
Fructus Corni 10 Rhizoma Imperataes 22
Cortex Phellodendri 15 Rhizoma Smilacis Glabraes 14
Stamen Nelumbinis 15 Radix Notoginseng 12.
3, a kind of medicine for the treatment of nephropathy according to claim 1, it is characterized in that: it is made up of following weight portion raw material:
Radix Astragali 15 Radix Ginsengs 10
Fructus Corni 10 Rhizoma Imperataes 20
Cortex Phellodendri 15 Rhizoma Smilacis Glabraes 15
Stamen Nelumbinis 15 Radix Notoginseng 10.
CNA031509436A 2003-09-12 2003-09-12 Kidney disease therapeutic pharmaceutical Pending CN1522743A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA031509436A CN1522743A (en) 2003-09-12 2003-09-12 Kidney disease therapeutic pharmaceutical

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Application Number Priority Date Filing Date Title
CNA031509436A CN1522743A (en) 2003-09-12 2003-09-12 Kidney disease therapeutic pharmaceutical

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CN1522743A true CN1522743A (en) 2004-08-25

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101439159B (en) * 2007-11-21 2011-04-27 丁立敬 Chinese medicinal composition for treating nephropathy and preparation thereof
CN103751293A (en) * 2014-01-12 2014-04-30 于秀莲 Traditional Chinese medicinal composition for treating chronic nephritis
CN104225342A (en) * 2014-10-14 2014-12-24 段永胜 Chinese herbal preparation for treating nephritis edema and preparation method thereof
CN104623412A (en) * 2015-01-31 2015-05-20 成都市飞龙水处理技术研究所青白江第一分所 Internally taking medicine for treating chronic nephritis (nephrotic type) and preparation method thereof
CN104800688A (en) * 2015-04-04 2015-07-29 康莉 Traditional Chinese medicine composition for treating chronic nephritis and application

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101439159B (en) * 2007-11-21 2011-04-27 丁立敬 Chinese medicinal composition for treating nephropathy and preparation thereof
CN103751293A (en) * 2014-01-12 2014-04-30 于秀莲 Traditional Chinese medicinal composition for treating chronic nephritis
CN103751293B (en) * 2014-01-12 2016-02-17 于秀莲 A kind of Chinese medicine composition for the treatment of chronic nephritis
CN104225342A (en) * 2014-10-14 2014-12-24 段永胜 Chinese herbal preparation for treating nephritis edema and preparation method thereof
CN104623412A (en) * 2015-01-31 2015-05-20 成都市飞龙水处理技术研究所青白江第一分所 Internally taking medicine for treating chronic nephritis (nephrotic type) and preparation method thereof
CN104800688A (en) * 2015-04-04 2015-07-29 康莉 Traditional Chinese medicine composition for treating chronic nephritis and application

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