CN1507894A - Medicine for treating gastrointestinal summer damp cold and preparing method thereof - Google Patents
Medicine for treating gastrointestinal summer damp cold and preparing method thereof Download PDFInfo
- Publication number
- CN1507894A CN1507894A CNA021496323A CN02149632A CN1507894A CN 1507894 A CN1507894 A CN 1507894A CN A021496323 A CNA021496323 A CN A021496323A CN 02149632 A CN02149632 A CN 02149632A CN 1507894 A CN1507894 A CN 1507894A
- Authority
- CN
- China
- Prior art keywords
- extract
- volatile oil
- medicine
- magnoliae officinalis
- cortex magnoliae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a pure Chinese medicine preparation for curing gastrointestinal type summer-heat and dampness common cold and its preparation method. Said invention adopts molecular distillation and supercritical CO2 fluid extraction equipment to extract the effective active substances of agastache/patchouli, magnolia bark, atractylodes root and dried ginger, after the agastache/patchouli extract, magnolia bark extract, atractylodes root extract and dried ginger extract are mixed according to a certain ratio, the medicinal vegetable oil auxiliary material is added, then they are made into the soft capsule by means of drum granule-pressing machine.
Description
One, technical field:
The present invention relates to a kind of medicine of gastrointestinal type summer-heat damp cold, specifically a kind of is the Chinese patent medicine of feedstock production with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Two, technical background:
Flu is modal frequently-occurring disease, and flu is often brought out diseases such as secondary bronchitis, pneumonia, the threat human beings'health.The name of flu, the beginning sees " all wind of Renzhai Zhi Zhi Fang, Effective Recipes from Renzhai House " piece of writing " it is low voice speaking to cough for flu ailment said due to cold or exposure, fever and headache, and tears saliva is sticky " of Yang Shiying in the Northern Song Dynasty.And before this flu that claim are " cold ", " ailment said due to cold or exposure " etc. more.Chief editors such as Wang Yongyan " clinical Chinese Internal Medicine " will catch a cold dialectical being divided into: anemofrigid cold, anemopyretic cold, exterior cold and interior heat, summer-heat damp cold, wind-dryness flu, deficiency of vital energy flu, yang deficiency flu, blood deficiency flu and deficiency of YIN flu etc.
Summer-heat damp cold is meant experiences the pathogenic summer-heat in summer, summer heat usually accompanied with dampness, and every many heat-damp in summers are laid equal stress on.Heat-damp in summer is hindered table, and table is defended discord, so fever of the body, micro evil wind, few, the limb aching pain of antiperspirant; Wind summer-heat folder is wet, and last criminal empties, then dizzy and headache; Summer-heat is violated lung, and lung qi is unclear, thus cough with ropy sputum, turbid nasal discharge; Disturb in the summer-heat, then vexed, thirsty, oliguria with reddish urine are hindered in the bright Tianjin of heat; Resistance in damp and hot, mechanism of qi is not opened up, so sticky in uncomfortable in chest, the nausea, mouth, polydipsia not yearningly; The tongue fur BOHUANG is greasy, soft and rapid pulse, is wet the levying of summer-heat folder.Its method of treatment is induced sweat for the clearing away summer-heat damp eliminating, and traditional prescription is for newly adding Xiangru Xin plus-minus (prescription is: the fragrant leaves of pulse plants, Flos Lonicerae, new Flos dolichoris, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, Fructus Forsythiae).
The medicine of prior art western medicines in treatment flu mostly is heat clearing away, antiinflammatory, antiallergic and antiviral class medicine, though malaise symptoms such as the heating that flu is caused, pain, cough, rhinorrhea have the effect of slowing down, but drowsiness, hyperhidrosis is arranged more, have in addition cause cardiovascular system and kidney untoward reaction.The traditional Chinese medical science is with a long history to the understanding of flu, and the prescription of treatment flu is numerous, and curative effect is sure.Yet the occupation mode of the flu of pure Chinese medicinal preparation treatment at present, be at most water decocting method or decoction and alcohol sedimentation technique, the medicinal liquid that obtains directly uses or is processed into required dosage form, the volatile position of active component in the crude drug then is difficult to keep, that is to say that the active component in the raw material is difficult to farthest extract and keep, thereby affect the treatment.
Three, summary of the invention:
The purpose of this invention is to provide a kind of pure Chinese medicinal preparation for the treatment of the gastrointestinal type summer-heat damp cold, another kind of purpose provides the preparation technology of this Chinese medicine preparation.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to the gastrointestinal type summer-heat damp cold, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out dispelling summer-heat from superficies of the body, the Herba Pogostemonis of removing dampness to restore normal function of the stomach, the circulation of qi promoting removing food stagnancy, dampness is removed full Cortex Magnoliae Officinalis, drying damp and strengthening spleen Rhizoma Atractylodis and warming spleen and stomach for dispelling cold, the Rhizoma Zingiberis that recuperating depleted YANG is promoted blood circulation, adopt modern biological medicine technologies such as carbon dioxide supercritical fluid extraction technology and molecular distillation, extract Chinese crude drug (Herba Pogostemonis to greatest extent, Cortex Magnoliae Officinalis, Rhizoma Atractylodis and Rhizoma Zingiberis) in the effective active composition, and the screening of the best proportioning of process, make pure Chinese medicinal preparation, treatment gastrointestinal type summer-heat damp cold, effect is remarkable.
Medicine of the present invention is made by following compositions in weight percentage:
Herba Pogostemonis extract 25%～45% Cortex Magnoliae Officinalis extract 10%～35%
Rhizoma Atractylodis extract 10%～35% Rhizoma Zingiberis extract 25%～45%
The formula optimization weight percent ratio range of preparation medicine of the present invention is:
Herba Pogostemonis extract 28%～38% Cortex Magnoliae Officinalis extract 12%～22%
Rhizoma Atractylodis extract 12%～22% Rhizoma Zingiberis extract 28%～38%
The optimum weight percentage ratio proportioning of preparation medicine of the present invention is:
Herba Pogostemonis extract 33% Cortex Magnoliae Officinalis extract 17%
Rhizoma Atractylodis extract 17% Rhizoma Zingiberis extract 33%
The preparation method of medicine of the present invention is:
1, with conventional steam distillation Herba Pogostemonis, obtains Herba Agastaches Rugosae volatile oil;
2, adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Agastaches Rugosae volatile oil, 90～170 ℃ of molecular distillation temperature, vacuum 200～500Pa * 10
-1
3, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
4, Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing adopts the supercritical carbon dioxide extraction device to extract effective active matter respectively, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 25～35 ℃, extracting pressure is 20～35mPa, and the extraction time is 1.5～2.5 hours; The extraction temperature of Rhizoma Atractylodis powder is 41～55 ℃, and extracting pressure is 20～30mPa, and the extraction time is 1.5～2.5 hours; The extraction temperature of ginger powder is 41～50 ℃, and extracting pressure is 25～30mPa, and the extraction time is 2.5～4.5 hours;
5, adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 90～170 ℃ of molecular distillation temperature, vacuum 200～500Pa * 10
-1
6, the Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oil, Rhzoma Atractylodis Lanceae volatile oil, Rhizoma Zingiberis volatile oil that will extract gained adds the medicinal plant oil adjuvant by after the described mixed, and reuse cylinder particle pressing machine is pressed into soft capsule.
The present invention compared with prior art has following advantage:
1, employing co_2 supercritical fluid extraction device extracts the effective active composition (being volatile oil) in Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the Rhizoma Zingiberis respectively, the extraction efficiency height, no solvent residue toxicity, active skull cap components and heat-sensitive ingredients are difficult for decomposing to be destroyed, and can keep the extract natural feature to greatest extent;
2, the employing molecular distillation apparatus extracts the effective active composition (being volatile oil) in the Herba Pogostemonis, and co_2 supercritical fluid extraction Rhizoma Atractylodis active component (being volatile oil) is carried out redistillation (removing fatty oil).Molecular distillation extraction separation ability is strong, effective ingredient enrichment degree height, and the extraction yield height, no solvent residue toxicity, active skull cap components and heat-sensitive ingredients are difficult for decomposing to be destroyed, and can keep the extract natural feature to greatest extent, and it is low to consume energy;
3, component of the present invention is few, and preparation technology is simple, and is easy and simple to handle;
4, experimental result show bring down a fever, antiinflammatory, that the promotion small intestinal promotes function is remarkable.
Experimentation overview of the present invention:
Testing 1 Dichlorodiphenyl Acetate induced mice capillary permeability increases, on lumbar injection acetic acid normal saline mouse model, when uniting when giving to give Herba Pogostemonis extract, Cortex Magnoliae Officinalis extract, Rhizoma Atractylodis extract and Rhizoma Zingiberis extract in described ratio, can obviously increase the mice capillary permeability, with model group, and give Herba Pogostemonis extract, Cortex Magnoliae Officinalis extract, Rhizoma Atractylodis extract and Rhizoma Zingiberis extract group not according to described ratio and compare, difference has significance, and showing has significant antiinflammatory action.
Test the experiment of 2 mouse small intestine propulsion functions, can't help in fasting on the mouse model of water (24 hours), when uniting when giving to give Herba Pogostemonis extract, Cortex Magnoliae Officinalis extract, Rhizoma Atractylodis extract and Rhizoma Zingiberis extract in described ratio, can obviously improve charcoal end propelling rate, with model group, and give Herba Pogostemonis extract, Cortex Magnoliae Officinalis extract, Rhizoma Atractylodis extract and Rhizoma Zingiberis extract group not according to described ratio and compare, difference has significance, and showing has the progradation of significant enhancement intestinal.
Test the experiment of having loose bowels of 3 rats, cause on the mouse model of having loose bowels gavaging Folium Sennae, when uniting when giving to give Herba Pogostemonis extract, Cortex Magnoliae Officinalis extract, Rhizoma Atractylodis extract and Rhizoma Zingiberis extract in described ratio, can obviously suppress mice has loose bowels, with model group, and give Herba Pogostemonis extract, Cortex Magnoliae Officinalis extract, Rhizoma Atractylodis extract and Rhizoma Zingiberis extract group not according to described ratio and compare, difference has significance, and showing has significant anti-diarrhea effect.
Four, the specific embodiment:
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment (one):
1, with conventional steam distillation Herba Pogostemonis, obtains rough Herba Agastaches Rugosae volatile oil;
2, adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Agastaches Rugosae volatile oil, 90 ℃ of molecular distillation temperature, vacuum 200Pa * 10
-1
3, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
4, the model that adopts Chinese dimension (HANDWAY) company to make respectively of Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing is that 100ml-SPE supercritical carbon dioxide extraction device extracts effective active matter, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 25 ℃, extracting pressure is 20mPa, and the extraction time is 2.5 hours; The extraction temperature of Rhizoma Atractylodis powder is 55 ℃, and extracting pressure is 30mPa, and the extraction time is～1.5 hours; The extraction temperature of ginger powder is 41 ℃, and extracting pressure is 30mPa, and the extraction time is 2.5 hours;
5, adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 170 ℃ of molecular distillation temperature, vacuum 500Pa * 10
-1
6, will extract gained 4.5 kilograms of mixing of 2.4 kilograms of 2.4 kilograms of 4.5 kilograms of Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oils, Rhzoma Atractylodis Lanceae volatile oils, Rhizoma Zingiberis volatile oil after, add the medicinal plant oil adjuvant, reuse cylinder particle pressing machine is pressed into soft capsule.
Embodiment (two):
1, with conventional steam distillation Herba Pogostemonis, obtains Herba Agastaches Rugosae volatile oil;
2, adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Agastaches Rugosae volatile oil, 110 ℃ of molecular distillation temperature, vacuum 400Pa * 10
-1
3, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
4, the model that adopts Chinese dimension (HANDWAY) company to make respectively of Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing is that 100ml-SPE supercritical carbon dioxide extraction device extracts effective active matter, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 35 ℃, extracting pressure is 25mPa, and the extraction time is 1.5 hours; The extraction temperature of Rhizoma Atractylodis powder is 41 ℃, and extracting pressure is 20mPa, and the extraction time is 2.5 hours; The extraction temperature of ginger powder is 50 ℃, and extracting pressure is 25mPa, and the extraction time is 2.5 hours;
5, adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 130 ℃ of molecular distillation temperature, vacuum 100Pa * 10
-1
6, will extract 7.5 kilograms of mixing of 4.8 kilograms of 4.8 kilograms of 7.5 kilograms of Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oils, Rhzoma Atractylodis Lanceae volatile oils, Rhizoma Zingiberis volatile oil of gained after, add the medicinal plant oil adjuvant, reuse cylinder particle pressing machine is pressed into soft capsule.
Embodiment (three):
1, with conventional steam distillation Herba Pogostemonis, obtains rough Herba Agastaches Rugosae volatile oil;
2, adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Pogostemonis refined volatile oil, 150 ℃ of molecular distillation temperature, vacuum 300Pa * 10
-1
3, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
4, the model that adopts Chinese dimension (HANDWAY) company to make respectively of Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing is that 100ml-SPE supercritical carbon dioxide extraction device extracts effective active matter, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 33 ℃, extracting pressure is 23mPa, and the extraction time is 2 hours; The extraction temperature of Rhizoma Atractylodis powder is 53 ℃, and extracting pressure is 27mPa, and the extraction time is 2 hours; The extraction temperature of ginger powder is 47 ℃, and extracting pressure is 27mPa, and the extraction time is 3.5 hours;
5, adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 110 ℃ of molecular distillation temperature, vacuum 400Pa * 10
-1
6,6.0 kilograms of 3.0 kilograms of 3.0 kilograms of 6.0 kilograms of Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oils, Rhzoma Atractylodis Lanceae volatile oils, the Rhizoma Zingiberis volatile oils that will extract gained adds the medicinal plant oil adjuvant by after the described mixed, and reuse cylinder particle pressing machine is pressed into soft capsule.
Embodiment (four):
1, with conventional steam distillation Herba Pogostemonis, obtains Herba Agastaches Rugosae volatile oil;
2, adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Agastaches Rugosae volatile oil, 170 ℃ of molecular distillation temperature, vacuum 200Pa * 10
-1
3, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
4, the model that adopts Chinese dimension (HANDWAY) company to make respectively of Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing is that 100ml-SPE supercritical carbon dioxide extraction device extracts effective active matter, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 30 ℃, extracting pressure is 21mPa, and the extraction time is 2.5 hours; The extraction temperature of Rhizoma Atractylodis powder is 48 ℃, and extracting pressure is 25mPa, and the extraction time is 2.5 hours; The extraction temperature of ginger powder is 45 ℃, and extracting pressure is 28mPa, and the extraction time is 4 hours;
5, adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 130 ℃ of molecular distillation temperature, vacuum 100Pa * 10
-1
6, will extract gained 9.0 kilograms of 6.0 kilograms of 6.0 kilograms of 9.0 kilograms of Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oils, Rhzoma Atractylodis Lanceae volatile oils, Rhizoma Zingiberis volatile oils by after the described mixed, add the medicinal plant oil adjuvant, reuse cylinder particle pressing machine is pressed into soft capsule.
Embodiment (five):
1, with conventional steam distillation Herba Pogostemonis, obtains Herba Agastaches Rugosae volatile oil;
2, adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Agastaches Rugosae volatile oil, 130 ℃ of molecular distillation temperature, vacuum 100Pa * 10
-1
3, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
4, the model that adopts Chinese dimension (HANDWAY) company to make respectively of Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing is that 100ml-SPE supercritical carbon dioxide extraction device extracts effective active matter, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 27 ℃, extracting pressure is 22mPa, and the extraction time is 2.5 hours; The extraction temperature of Rhizoma Atractylodis powder is 44 ℃, and extracting pressure is 22mPa, and the extraction time is 2.5 hours; The extraction temperature of ginger powder is 43 ℃, and extracting pressure is 26mPa, and the extraction time is 4 hours;
5, adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 170 ℃ of molecular distillation temperature, vacuum 200Pa * 10
-1
6, will extract gained 3.0 kilograms of 1.2 kilograms of 1.2 kilograms of 3.0 kilograms of Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oils, Rhzoma Atractylodis Lanceae volatile oils, Rhizoma Zingiberis volatile oils by after the described mixed, add the medicinal plant oil adjuvant, reuse cylinder particle pressing machine is pressed into soft capsule.
Claims (6)
1, a kind of medicine for the treatment of the gastrointestinal type summer-heat damp cold is characterized in that: preparing the raw extract component of this medicine and the weight percent proportioning of component is:
Herba Pogostemonis extract 25%～45% Cortex Magnoliae Officinalis extract 10%～35%
Rhizoma Atractylodis extract 10%～35% Rhizoma Zingiberis extract 25%～45%
2, the medicine of treatment gastrointestinal type summer-heat damp cold according to claim 1 is characterized in that: preparing the raw extract component of this medicine and the preferred weight per distribution ratio of component is:
Herba Pogostemonis extract 28%～38% Cortex Magnoliae Officinalis extract 12%～22%
Rhizoma Atractylodis extract 12%～22% Rhizoma Zingiberis Recens extract 28%～38%
3, the medicine of treatment gastrointestinal type summer-heat damp cold according to claim 1 is characterized in that: preparing the raw extract component of this medicine and the optimum weight per distribution ratio of component is:
Herba Pogostemonis extract 33% Cortex Magnoliae Officinalis extract 33%
Rhizoma Atractylodis extract 17% Rhizoma Zingiberis extract 17%
4, according to the medicine of claim 1,2 or 3 described treatment gastrointestinal type summer-heat damp colds, it is characterized in that: described medicament is a said dosage form on any pharmaceutics.
5, the medicine of treatment gastrointestinal type summer-heat damp cold according to claim 4, it is characterized in that: described medicament is a soft capsule.
6, the preparation method of the described treatment gastrointestinal type of claim 5 summer-heat damp cold medicine is characterized in that may further comprise the steps:
(1) with conventional steam distillation Herba Pogostemonis, obtains Herba Agastaches Rugosae volatile oil;
(2) adopt molecular distillation apparatus distillation Herba Agastaches Rugosae volatile oil, refining Herba Agastaches Rugosae volatile oil, 90～170 ℃ of molecular distillation temperature, vacuum 200～500Pa * 10
-1
(3) Cortex Magnoliae Officinalis, Rhizoma Atractylodis, the ginger powder after will drying respectively is broken to 20 order fine powders;
(4) Cortex Magnoliae Officinalis powder, Rhizoma Atractylodis powder, the ginger powder after will pulverizing adopts the supercritical carbon dioxide extraction device to extract effective active matter respectively, wherein the extraction temperature of Cortex Magnoliae Officinalis powder is 25～35 ℃, extracting pressure is 20～25mPa, and the extraction time is 1.5～2.5 hours; The extraction temperature of Rhizoma Atractylodis powder is 41～50 ℃, and extracting pressure is 20～30mPa, and the extraction time is 1.5～2.5 hours; The extraction temperature of ginger powder is 41～50 ℃, and extracting pressure is 25～30mPa, and the extraction time is 2.5～4.5 hours;
(5) adopt molecular distillation apparatus distillation Rhzoma Atractylodis Lanceae volatile oil, refining Rhzoma Atractylodis Lanceae volatile oil, 90～170 ℃ of molecular distillation temperature, vacuum 200～500Pa * 10
-1
(6) Herba Agastaches Rugosae volatile oil, Cortex Magnoliae Officinalis volatile oil, Rhzoma Atractylodis Lanceae volatile oil, Rhizoma Zingiberis volatile oil that will make with extra care and extract gained by described mixed after, add the medicinal plant oil adjuvant, reuse cylinder particle pressing machine is pressed into soft capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021496323A CN100417410C (en) | 2002-12-16 | 2002-12-16 | Medicine for treating gastrointestinal summer damp cold and preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021496323A CN100417410C (en) | 2002-12-16 | 2002-12-16 | Medicine for treating gastrointestinal summer damp cold and preparing method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1507894A true CN1507894A (en) | 2004-06-30 |
| CN100417410C CN100417410C (en) | 2008-09-10 |
Family
ID=34233710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021496323A Expired - Fee Related CN100417410C (en) | 2002-12-16 | 2002-12-16 | Medicine for treating gastrointestinal summer damp cold and preparing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100417410C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1632240A1 (en) * | 2004-07-01 | 2006-03-08 | Yangsen Biotechnology Co., Ltd | Essential oils for treating and/or preventing allergic disease |
| CN101301074B (en) * | 2008-05-20 | 2012-09-05 | 江南大学 | Technique for preparing health care drink series using fresh Agastache leaf as raw material |
| CN102965190A (en) * | 2012-12-04 | 2013-03-13 | 师宗红盈食品有限公司 | Ginger essential oil extraction method |
| CN107875366A (en) * | 2017-12-08 | 2018-04-06 | 江苏师范大学 | A kind of Chinese medicine sachet prevented for phlegm wet matter crowd's flu-prevention |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1031318C (en) * | 1991-07-24 | 1996-03-20 | 四川涪陵制药厂 | Method for preparation of oral liquid of agastachis for restoring health |
-
2002
- 2002-12-16 CN CNB021496323A patent/CN100417410C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1632240A1 (en) * | 2004-07-01 | 2006-03-08 | Yangsen Biotechnology Co., Ltd | Essential oils for treating and/or preventing allergic disease |
| CN101301074B (en) * | 2008-05-20 | 2012-09-05 | 江南大学 | Technique for preparing health care drink series using fresh Agastache leaf as raw material |
| CN102965190A (en) * | 2012-12-04 | 2013-03-13 | 师宗红盈食品有限公司 | Ginger essential oil extraction method |
| CN107875366A (en) * | 2017-12-08 | 2018-04-06 | 江苏师范大学 | A kind of Chinese medicine sachet prevented for phlegm wet matter crowd's flu-prevention |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100417410C (en) | 2008-09-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1317027C (en) | Chinese medicine for treating depression | |
| CN1742939A (en) | Medicine for treating pulmonary fibrosis and preparing method | |
| CN1565601A (en) | Application of sichuan lovage rhizome oil by supercritical CO2 extraction method in pharmacy | |
| CN1150930C (en) | Cinnamon twig decoction extract for preventing and curing hypertension | |
| CN101053619A (en) | Medicine for treating pulmonary fibrosis | |
| CN105582124B (en) | Chinese medicinal composition for treating constipation, and its preparation method | |
| CN1052897C (en) | Chinese proprietary medicine for curing cold | |
| CN100417410C (en) | Medicine for treating gastrointestinal summer damp cold and preparing method thereof | |
| CN1298362C (en) | Compound Chinese medicine prepn for treating pulvic infection and its prepn process | |
| CN1883533A (en) | Pharmaceutical composition for treating apoplexy and preparation method thereof | |
| CN1785391A (en) | Chinese medicinal composition and its preparation method | |
| CN1232279C (en) | Antilipemic Chinese medicine | |
| CN101062341A (en) | Traditional Chinese medicinal preparation for treating pulmonary tuberculosis | |
| CN1781516A (en) | Method for preparing piper laetispicum extract, extract and its use | |
| CN1437983A (en) | Plaster for treating dysmenorrhoea and preparation method | |
| CN1259945C (en) | Antipyretic Chinese medicine preparation for child made of bupleurum root and cinnamon twig | |
| CN101700385B (en) | Pharmaceutical composition medicinal liquor or tincture for curing white vein disease and preparation method thereof | |
| CN102266538A (en) | Traditional Chinese medicinal composition for treating damp-heat dysentery and preparation method thereof | |
| CN1239188C (en) | Use of Chinese medicine composition in preparing medicine for anti SARS virus | |
| CN1876087A (en) | A medicament for treating tension headache and preparation method thereof | |
| CN1931208A (en) | Application of common goldenrod herb in preparing medicine for preventing and treating H5N1 bird flu and influenza | |
| CN1883660A (en) | Blood fat-reducing Chinese medicine and preparation method thereof | |
| CN1827119A (en) | Chinese medicinal compound preparation capable of relieving exterior syndrome, digesting food and eliminating sputum and method for preparing the same | |
| CN1726960A (en) | Combination of effective parts for curing chronic hepatitis, preparation and usage | |
| CN1606987A (en) | Allergy-resistant constituent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080910 Termination date: 20111216 |