CN1502328A - Lamiophlomis rotate dispersion table preparation process - Google Patents
Lamiophlomis rotate dispersion table preparation process Download PDFInfo
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- CN1502328A CN1502328A CNA021341699A CN02134169A CN1502328A CN 1502328 A CN1502328 A CN 1502328A CN A021341699 A CNA021341699 A CN A021341699A CN 02134169 A CN02134169 A CN 02134169A CN 1502328 A CN1502328 A CN 1502328A
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- radix lamiophlomidis
- lamiophlomidis rotatae
- dispersible tablet
- minutes
- pain
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Abstract
The present invention relates to a preparation method of lamiophlomis rotata dispering tablet which can be quickly disintegrated and can quickly produce action. Its preparation method includes the following steps: decocting the Chinese medicinal material lamiophlomis rotate for three times, every time is 1 hr., filtering and removing impurity, concentrating, drying, adding auxiliary material, granulating and tableting so as to obtain the invented product whose active component is total flavone. Said product is mainly used for curing several diseases of postoperative cutting edge pain, hemorrhage, traumatic fracture, sprain and others.
Description
The technical field pharmaceutical technology
Background technology Radix Lamiophlomidis Rotatae sheet is a kind of traditional Chinese patent medicine, records in " Chinese pharmacopoeia [in 2000, function is a promoting blood circulation and stopping pain, removing stasis to stop bleeding.Be used for the edge of a knife pain behind the multiple surgical operation, hemorrhage, exogenous injury, muscles and bones is sprained, rheumatic arthralgia and metrorrhagia, dysmenorrhea, gingival swelling and pain is hemorrhage etc.
The Radix Lamiophlomidis Rotatae sheet is as the edge of a knife pain of treatment behind the surgical operation, hemorrhage, exogenous injury, muscles and bones is sprained, rheumatic arthralgia and metrorrhagia, dysmenorrhea, gingival swelling and pain, the hemorrhage traditional Chinese patent medicine that waits disease, its curative effect is definite, but the edge of a knife pain behind the surgical operation, hemorrhage, exogenous injury, muscles and bones is sprained, rheumatic arthralgia and metrorrhagia, dysmenorrhea, gingival swelling and pain, disease such as hemorrhage is acute disease, and the Radix Lamiophlomidis Rotatae sheet has shortcomings such as disintegration time is long, onset is slow, can not in time alleviate, treat the pain of these diseases, symptom such as hemorrhage.
Dispersible tablet is the new pharmaceutical technology that grows up the sixties, can make the quick disintegrate of medicine reach homogeneously dispersed state, and effective ingredient stripping fast enters blood and onset.
Based on above situation, my special further investigation, uses advanced dispersible tablet technology with the Radix Lamiophlomidis Rotatae sheet make can quick acting the Radix Lamiophlomidis Rotatae dispersible tablet, be used for the treatment of the edge of a knife pain behind the multiple surgical operation, hemorrhage, exogenous injury, muscles and bones is sprained, rheumatic arthralgia and metrorrhagia, dysmenorrhea, gingival swelling and pain hemorrhagely waits sickly, has solved that Radix Lamiophlomidis Rotatae sheet disintegration time is long, onset shortcoming slowly.
Consult document, do not have the report of Radix Lamiophlomidis Rotatae dispersible tablet.
The summary of the invention Radix Lamiophlomidis Rotatae is pulverized, decoct with water three times, each 1 hour, filter remove impurity, concentrate, dry, add adjuvants such as carboxymethyl starch sodium, microcrystalline Cellulose, granulate tabletting, promptly get in 3 minutes disintegrate fully and reach the Radix Lamiophlomidis Rotatae dispersible tablet of homogeneously dispersed state, its effective ingredient total flavones (in rutin) cumulative leaching rate in the time of 10 minutes reaches more than 60%.For the edge of a knife pain behind the multiple surgical operation, hemorrhage, exogenous injury, muscles and bones is sprained, rheumatic arthralgia and metrorrhagia, dysmenorrhea, gingival swelling and pain, the treatment of disease such as hemorrhage provides a kind of new medicine.
Specific embodiment Radix Lamiophlomidis Rotatae is ground into granule, decocts with water each 1 hour three times, filter remove impurity, being concentrated into relative density is 1.30 (85 ℃), and 80 ℃ of dryings add adjuvants such as carboxymethyl starch sodium, microcrystalline Cellulose, granulate, add micropowder silica gel, mixing, tabletting, promptly get in 3 minutes disintegrate fully and reach the Radix Lamiophlomidis Rotatae dispersible tablet of homogeneously dispersed state, its effective ingredient total flavones (in rutin) cumulative leaching rate in the time of 10 minutes reaches more than 60%.
Claims (1)
- Technical characterictic is the edge of a knife pain that is used for the treatment of behind the multiple surgical operation, hemorrhage, exogenous injury, muscles and bones is sprained, rheumatic arthralgia and metrorrhagia, dysmenorrhea, gingival swelling and pain, hemorrhagely wait sick new product of Chinese medicine---Radix Lamiophlomidis Rotatae dispersible tablet, this Radix Lamiophlomidis Rotatae dispersible tablet can 3 minutes in disintegrate and reach homogeneously dispersed state fully, its effective ingredient total flavones (in rutin) cumulative leaching rate in the time of 10 minutes reaches more than 60%.The preparation method of Radix Lamiophlomidis Rotatae dispersible tablet is: Radix Lamiophlomidis Rotatae is pulverized, decoct with water three times, each 1 hour, filter remove impurity, concentrate, dry, add adjuvants such as carboxymethyl starch sodium, microcrystalline Cellulose, granulate tabletting, promptly get in 3 minutes disintegrate fully and reach the Radix Lamiophlomidis Rotatae dispersible tablet of homogeneously dispersed state, its effective ingredient total flavones (in rutin) cumulative leaching rate in the time of 10 minutes reaches more than 60%.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNA021341699A CN1502328A (en) | 2002-11-26 | 2002-11-26 | Lamiophlomis rotate dispersion table preparation process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CNA021341699A CN1502328A (en) | 2002-11-26 | 2002-11-26 | Lamiophlomis rotate dispersion table preparation process |
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CN1502328A true CN1502328A (en) | 2004-06-09 |
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CNA021341699A Pending CN1502328A (en) | 2002-11-26 | 2002-11-26 | Lamiophlomis rotate dispersion table preparation process |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100450502C (en) * | 2004-09-29 | 2009-01-14 | 广州陈李济药厂 | Active extract of lamtophlomis rotata and its preparing method and use |
CN103550289A (en) * | 2013-11-15 | 2014-02-05 | 石家庄市华新药业有限责任公司 | Lamiophlomis rotata soft capsule and preparation method thereof |
CN104147106A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Drying method of lamiophlomis rotata |
-
2002
- 2002-11-26 CN CNA021341699A patent/CN1502328A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100450502C (en) * | 2004-09-29 | 2009-01-14 | 广州陈李济药厂 | Active extract of lamtophlomis rotata and its preparing method and use |
CN103550289A (en) * | 2013-11-15 | 2014-02-05 | 石家庄市华新药业有限责任公司 | Lamiophlomis rotata soft capsule and preparation method thereof |
CN104147106A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Drying method of lamiophlomis rotata |
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