CN1064540C - Medicine for burn and scald - Google Patents
Medicine for burn and scald Download PDFInfo
- Publication number
- CN1064540C CN1064540C CN96117728A CN96117728A CN1064540C CN 1064540 C CN1064540 C CN 1064540C CN 96117728 A CN96117728 A CN 96117728A CN 96117728 A CN96117728 A CN 96117728A CN 1064540 C CN1064540 C CN 1064540C
- Authority
- CN
- China
- Prior art keywords
- radix
- component
- parts
- medicine
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses medicine for treating burns and scalds, which comprises three compound components, wherein the first component comprises the raw materials of phellodendron bark, gardenia, astragalus roots, dahurian angelica roots, balloon flowers, coptis, licorice roots, Chinese angelica and benne oil; the second component comprises the raw materials of spica prunellae, plantain herbs, bunge corydalis herbs, common calanthe herbs, alkanna tinctoria, honeysuckle flowers and benne oil; the third component comprises the raw materials of antelope's horns, borneol, honeycombs and musk. The medicine for treating burns and scalds has a peculiar pharmaceutical recipe and a preparation method. Three semi-finished products are firstly and respectively made by different methods. Then, the semi-finished products are proportionally prepared. The present invention has a particularly notable medical treatment effect.
Description
The present invention relates to a kind of medicine for the treatment of burn and scald, it is to be the Chinese patent medicine that raw material is made by Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Burn and scald is one of wound common in the human daily life, and Therapeutic Method such as dryness therapy and operative treatment etc. commonly used can run into following point mostly: patient's pain; Traumatic infection; Medical condition and facility require high, and healing time is long, stay cicatrix etc. after healing.Though also there are some Chinese patent medicine medicine for external use partly to address the above problem, not very good to the deep burn therapeutic effect.
The purpose of this invention is to provide the rapid pain relieving of a kind of energy, avoid traumatic infection, promote wound healing and the treated depth of preventing from scar and the Chinese patent medicine medicine of III ° burn and scald.
Another object of the present invention provides the preparation method of this burn and scald medicine.
The object of the present invention is achieved like this:
Medicine of the present invention is to be made by following three kinds of compound recipe components, and its weight proportion is: component one 50-80 part, component two 10-40 parts, component three 5-25 parts.
Three kinds of compound recipe components are made by following materials of weight proportions respectively:
Component one Cortex Phellodendri 1-8 part Fructus Gardeniae 1-8 part Radix Astragali 1-7 part
Radix Angelicae Dahuricae 1-8 part Radix Platycodonis 1-8 part Rhizoma Coptidis 1-7 part
Radix Glycyrrhizae 1-6 part Radix Angelicae Sinensis 1-6 part Oleum Sesami 30-70 part
Component two Spica Prunellae 1-5 part Herba Plantaginis 1-5 part Herba Violae 1-5 parts
Herba seu Radix Calanthes 1-5 part Radix Arnebiae (Radix Lithospermi) 1-5 part Flos Lonicerae 1-7 part
Oleum Sesami 5-20 part
Component three Cornu Saigae Tataricae 1-5 part Borneolum Syntheticum 1-8 part Nidus Vespae 3-10 parts
Moschus 3-9 part
The weight proportion preferable range of three kinds of compound recipe components of preparation medicine of the present invention is: component one 60-75 part, component two 10-30 part components three 10-20 parts
The preferred weight ratio range of forming the raw material of three kinds of compound recipe components is respectively:
Component one Cortex Phellodendri 2-5 part Fructus Gardeniae 2-6 part Radix Astragali 2-5 part
Radix Angelicae Dahuricae 2-5 part Radix Platycodonis 2-5 part Rhizoma Coptidis 2-4 part
Radix Glycyrrhizae 2-4 part Radix Angelicae Sinensis 2-4 part Oleum Sesami 35-60 part
Component two Spica Prunellae 1-3 part Herba Plantaginis 1-3 part Herba Violae 2-3 parts
Herba seu Radix Calanthes 2-3 part Radix Arnebiae (Radix Lithospermi) 2-4 part Flos Lonicerae 2-5 part
Oleum Sesami 5-15 part
Component three Cornu Saigae Tataricae 1-3 part Borneolum Syntheticum 3-7 part Nidus Vespae 3-7 parts
Moschus 4-8 part
The optimum weight ratio of three kinds of compound recipe components of medicine of the present invention is one 65 parts of components, 2 25 parts of components, 3 10 parts of components.
The optimum weight ratio of forming the raw material of three kinds of compound recipe components is:
3 parts of 4 parts of Radixs Astragali of 3 parts of Fructus Gardeniae of component one Cortex Phellodendri
2 parts of 3 portions of Rhizoma Coptidis of 4 parts of Radix Platycodoniss of the Radix Angelicae Dahuricae
40 parts in 2 parts of Oleum Sesami of 3 parts of Radix Angelicae Sinensis of Radix Glycyrrhizae
2 parts of 2 parts of Herba Violaes of 2 portions of Herba Plantaginiss of component two Spica Prunellaes
3 parts of 3 portions of Flos Loniceraes of 2 portions of Radix Arnebiae (Radix Lithospermi)s of Herba seu Radix Calanthes
10 parts in Oleum Sesami
4 parts in 2 parts of Nidus Vespae of 2 parts of Borneolum Syntheticums of component three Cornu Saigae Tataricae
2 parts in Moschus
With above-mentioned each component preparation cost invention medicine production method be:
1, preparation component one:
Oleum Sesami heated to 80 ℃-90 ℃ put into Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Platycodonis, constant temperature is heated after 30 minutes to 150 ℃-170 ℃ and is added Fructus Gardeniae, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Radix Angelicae Sinensis then, heat to 220 ℃ of-250 ℃ of constant temperature 150 minutes, the filtering medicinal residues, it is stand-by to be cooled to room temperature.
2, preparation component two:
Spica Prunellae, Herba Plantaginis, Herba Violae, Herba seu Radix Calanthes, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae are put into Oleum Sesami soaked 20 days, heat then to 150 ℃ of-170 ℃ of constant temperature 90 minutes, the filtering medicinal residues are cooled to room temperature.
3, preparation component three:
Earlier Cornu Saigae Tataricae is mashed powdered, again Nidus Vespae is heated to 80 ℃-90 ℃ dissolve after, put into Cornu Saigae Tataricae powder, constant temperature 90 drags for floating thing, puts into Borneolum Syntheticum when being cooled to 50 ℃-60 ℃, Moschus stirs evenly, and is incubated 10 minutes and is chilled to room temperature.
4, with component one, two, three in described ratio, heat fusing back of component one is added component two, heat again to 70 ℃-90 ℃, add component three and stir, postcooling to room temperature promptly got medicine of the present invention in 10 minutes, medicine of the present invention is an ointment shape medicament.
In use, only needing that medicine of the present invention is coated on the burn and scald affected part gets final product.
The advantage of medicine of the present invention is that a depth and an III ° burn and scald are had the obvious treatment effect, and tangible bacteriostasis and antiinflammatory, analgesic effect are arranged, and also has the function of blood circulation promoting and blood stasis dispelling simultaneously, and the result is as follows in zoopery (burn model):
(1) influence that depth is scalded sees Table 1 table 2.
Table 1 medicine of the present invention is to the influence of rabbit depth scalding healing area (X ± S)
Annotate: (1) matched group have 3 animals to cause injury part is suppurated, is festered, perforation, necrosis.
(2) compare * P＜0.05 with matched group, △ P＜0.05 is compared with ZHENGHONGHUA YOU in * * P＜0.01.
The influence that table 2 medicine of the present invention changes scald sexually transmitted disease (STD) reason (X ± S)
Annotate: (1) 0 grade=0.5 minute; I level=1 minute; II level=2 minute; III level=3 minute.
(2) compare * * P＜0.01 with matched group, △ △ and effective relatively P＜0.01 of organizing.
(3) 0 grades: repair well, healing fully; I level: inflammatory reaction is arranged, no cicatrization;
The II level: existing inflammatory reaction has cicatrization again; III level: local tissue necrosis or scar contracture is arranged
From table 1, table 2 as can be seen, two dosage groups of medicine of the present invention all can obviously improve the wound healing rate, shorten treatment cycle, and the reaction that can reduce inflammation, and promote wound healing, suppress cicatrization, and are evident in efficacy to the depth scald.
(2), see Table 3, table 4 to the influence of eschar burn.
Table 3 medicine of the present invention is to the fall influence (X ± S) of area of rabbit eschar burn crust emaciated face
Annotate: compare * * P＜0.01 with matched group
Table 4 medicine of the present invention is to the influence of rabbit burn wound healing area (X ± S)
Annotate: compare * * P＜0.01 with matched group
The experimental data of table 3, table 4 shows, two the dosage groups and the Ag-SD frost of medicine of the present invention all can promote the healing of wound surface and quicken its decrustation, and the cicatrization of medicine of the present invention is white rarely than Ag-SD; Through pathological examination, Drug therapy eschar burn healing degree of the present invention is good, and epithelial repair is complete, does not see inflammatory cell infiltration, does not also have the cicatrization performance, and therefore, medicine of the present invention also is very conspicuous to the curative effect of eschar burn.(3) bacteriostatic test and drug sensitive experiment:
Test organisms is a gold-coloured staphylococci, bacillus pyocyaneus, and escherichia coli, the minimum inhibitory concentration of medicine of the present invention is 0.005g/ml, in the culture medium of 0.1g/ml and 0.05g/ml, three kinds of antibacterials all can not grow;
In the coating plate of above-mentioned three kinds of test organismss, the inhibition zone that medicine of the present invention produces is respectively: 13mm, and 12mm, 12mm all belongs to medium sensitivity.
The above results shows that medicine of the present invention prevents that to suppressing germ reproduction traumatic infection has good effect.
(4) antiinflammatory test sees Table 5, table 6.
Table 5 medicine of the present invention is to the influence of mice dimethylbenzene swelling of auricle (X ± S)
Annotate: * * and matched group compare P＜0.01: △ and dexamethasone compares P＜0.05
Table 6 medicine of the present invention is to the influence of rat Ovum Gallus domesticus album swollen joint (X ± S)
Annotate: * with compare P＜0.05, * * P＜0.01;
△ and Dexamethasone group be P＜0.05 relatively, △ △ P＜0.01.
The data of table 5, table 6 show that two dosage groups of the present invention all have stronger antiinflammatory action, but than a little less than the special anti-inflammatory drug dexamethasone.(5) analgesic test sees Table 7, table 8.
Table 7 medicine of the present invention is to the influence of thermostimulation pain (X ± S)
Annotate: compare * P＜0.05, * * P＜0.01 with matched group.
Table 8 medicine of the present invention is to the influence of chemical pain due to the acetic acid (X ± S)
Annotate: compare * * P＜0.01 with matched group.
Experimental result shows, medicine of the present invention has significant analgesia role to chemical pain due to thermostimulation pain and the acetic acid.
(6) blood circulation promoting and blood stasis dispelling experiment sees Table 9.
Table 9 medicine of the present invention is to the microcirculatory influence of the former film of mice intestinal
Annotate: compare * P＜0.05, * * P＜0.01 with matched group;
Compare △ P＜0.05, △ △ P＜0.01 with ZHENGHONGHUA YOU.
Table 9 is the result show, two dosage groups of medicine of the present invention all have the effect of microcirculation improvement in various degree, and this healing to empyrosis wound surface is very helpful.
Embodiment:
Component one: 2.5 kilograms of Cortex Phellodendris, 3.5 kilograms of Fructus Gardeniaes, 2.8 kilograms of the Radixs Astragali, 3.5 kilograms of the Radixs Angelicae Dahuricae, 3 kilograms of Radix Platycodoniss, 2.2 kilograms of Rhizoma Coptidis, 3.5 kilograms in Radix Glycyrrhizae, 2 kilograms of Radix Angelicae Sinensis, 35 kilograms in Oleum Sesami.
Oleum Sesami is heated to 80 ℃, add Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Platycodonis, constant temperature was heated to 160 ℃ after 30 minutes, added Fructus Gardeniae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis.Heat again to 240 ℃, constant temperature 150 minutes, the filtering medicinal residues, it is standby to be cooled to room temperature.
Component two: 2.3 kilograms of Spica Prunellaes, 2 kilograms of Herba Plantaginiss, 2.5 kilograms of Herba Violaes, 1.5 kilograms of Herba seu Radix Calanthess, 3.5 kilograms of Radix Arnebiae (Radix Lithospermi)s, 2.7 kilograms of Flos Loniceraes, 12 kilograms in Oleum Sesami.
With Spica Prunellae, Herba Plantaginis, Herba Violae, Herba seu Radix Calanthes, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae are put into Oleum Sesami and soaked 20 days, heat then to 160 ℃, constant temperature 90 minutes, the filtering medicinal residues, it is standby to be cooled to room temperature.
Component three: 2 kilograms of Cornu Saigae Tataricae, 2.5 kilograms of Borneolum Syntheticums, 4.5 kilograms in Nidus Vespae, 2.4 kilograms in Moschus.
Earlier Cornu Saigae Tataricae is smash powdered, Nidus Vespae is heated to 80 ℃ of fusings again, add Cornu Saigae Tataricae powder, constant temperature 90 minutes drags for floating thing, adds Borneolum Syntheticum, Moschus when being cooled to 60 ℃, and it is standby to be cooled to room temperature again.
Get one 35 kilograms of components, 2 10 kilograms of components, 35 kilograms of components.Earlier component one is heated and dissolve, add component three when heating to 80 ℃ again behind the adding component two and stir evenly, postcooling to room temperature got final product in 10 minutes.
Claims (5)
1. a medicine for the treatment of burn and scald is characterized in that it is prepared from by three kinds of compound recipe components of following weight ratio: component one 50-80 part, component two 10-40 parts, component three 5-25 parts; Three kinds of compound recipe components are made component one by the raw material of following weight ratio respectively: Cortex Phellodendri 1-8 part Fructus Gardeniae 1-8 part Radix Astragali 1-7 part
Radix Angelicae Dahuricae 1-8 part Radix Platycodonis 1-8 part Rhizoma Coptidis 1-7 part
Radix Glycyrrhizae 1-6 part Radix Angelicae Sinensis 1-6 part Oleum Sesami 30-70 part component two: Spica Prunellae 1-5 part Herba Plantaginis 1-5 part Herba Violae 1-5 part
Herba seu Radix Calanthes 1-5 part Radix Arnebiae (Radix Lithospermi) 1-5 part Flos Lonicerae 1-7 part
Oleum Sesami 5-20 part component three: Cornu Saigae Tataricae 1-5 part Borneolum Syntheticum 1-8 part Nidus Vespae 3-10 part
Moschus 3-9 part
2. the medicine of treatment burn and scald according to claim 1, the weight ratio of its three kinds of components are component one 60-75 part, component two 10-30 parts, component three 10-20 parts; The raw material weight ratio of forming three kinds of components respectively is: component one: Cortex Phellodendri 2-5 part, Fructus Gardeniae 2-6 part, Radix Astragali 2-5 part
Radix Angelicae Dahuricae 2-5 part, Radix Platycodonis 2-5 part, Rhizoma Coptidis 2-4 part
Radix Glycyrrhizae 2-4 part Radix Angelicae Sinensis 2-4 part, Oleum Sesami 35-60 part component two: Spica Prunellae 1-3 part Herba Plantaginis 1-3 part Herba Violae 2-3 part
Herba seu Radix Calanthes 2-3 part Radix Arnebiae (Radix Lithospermi) 2-4 part Flos Lonicerae 2-5 part
Oleum Sesami 5-15 part component three: Cornu Saigae Tataricae 1-3 part Borneolum Syntheticum 3-7 part Nidus Vespae 3-7 part
Moschus 4-8 part
3. the medicine of treatment burn and scald according to claim 1, its three kinds of component weight ratios are: component-65 part, 2 25 parts of components, 3 10 parts of components; The raw material weight ratio of forming three kinds of compound recipe components respectively is
Component one: 3 parts of 4 parts of Radixs Astragali of 3 portions of Fructus Gardeniaes of Cortex Phellodendri
2 parts of 3 parts of Rhizoma Coptidis of 4 parts of Radix Platycodoniss of the Radix Angelicae Dahuricae
40 parts in 2 parts of Oleum Sesami of 3 parts of Radix Angelicae Sinensis of Radix Glycyrrhizae
Component two: 2 parts of 2 parts of Herba Violaes of 2 portions of Herba Plantaginiss of Spica Prunellae
3 parts of 3 portions of Flos Loniceraes of 2 portions of Radix Arnebiae (Radix Lithospermi)s of Herba seu Radix Calanthes
10 parts in Oleum Sesami
Component three: 2 parts in 4 parts of Moschus of 2 parts of Nidus Vespae of 2 parts of Borneolum Syntheticums of Cornu Saigae Tataricae
4. according to the medicine of the described treatment burn and scald of claim 1,2 or 3, it is characterized in that it is a kind of paste medicament.
5. the preparation method of the medicine of treatment burn and scald according to claim 4 is characterized in that: component one is earlier Oleum Sesami to be heated after 80 ℃-90 ℃, puts into Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Platycodonis, constant temperature is heated after 30 minutes to 150 ℃-170 ℃, adds Fructus Gardeniae again, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Radix Angelicae Sinensis is heated to 220 ℃-250 ℃ constant temperature 150 minutes again, the elimination medicinal residues are cooled to room temperature; Component two is with Spica Prunellae, Herba Plantaginis, and Herba seu Radix Calanthes, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae are put into Oleum Sesami and soaked 20 days, heat then to 150 ℃ of-170 ℃ of constant temperature 90 minutes, and the filtering medicinal residues are cooled to room temperature; Component three is earlier Cornu Saigae Tataricae to be mashed powdered, Nidus Vespae is heated to 80 ℃ of-90 ℃ of fusings again, adds Cornu Saigae Tataricae powder, and constant temperature 90 minutes drags for floating thing, puts into Borneolum Syntheticum, Moschus when being cooled to 50 ℃-60 ℃, is cooled to room temperature again; At last component one is dissolved, add component two, heat again, add component three, stir evenly, be incubated 10 minutes postcooling to room temperature and get final product to 70 ℃-90 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96117728A CN1064540C (en) | 1996-10-02 | 1996-10-02 | Medicine for burn and scald |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96117728A CN1064540C (en) | 1996-10-02 | 1996-10-02 | Medicine for burn and scald |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1178109A CN1178109A (en) | 1998-04-08 |
| CN1064540C true CN1064540C (en) | 2001-04-18 |
Family
ID=5124551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96117728A Expired - Fee Related CN1064540C (en) | 1996-10-02 | 1996-10-02 | Medicine for burn and scald |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1064540C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829234B (en) * | 2010-05-27 | 2011-10-05 | 骆书祥 | Bothriospermum chinense and downy groundcherry fruitor herb ointment for treating burns and scalds and preparation method thereof |
| CN103083518A (en) * | 2012-12-28 | 2013-05-08 | 青岛爱维互动信息技术有限公司 | Tibetan medicine patch for treating wound |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082414A (en) * | 1992-08-01 | 1994-02-23 | 陆振雄 | A kind of production method of the medicine of burning |
| CN1107733A (en) * | 1994-12-02 | 1995-09-06 | 李钧 | Heat-clearing and detoxifying drug for external use |
| CN1116539A (en) * | 1995-04-24 | 1996-02-14 | 刘景文 | Burn and scald curing ointment |
| CN1127129A (en) * | 1995-01-16 | 1996-07-24 | 徐永林 | External application medicine for burn and scald and preparing method |
-
1996
- 1996-10-02 CN CN96117728A patent/CN1064540C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082414A (en) * | 1992-08-01 | 1994-02-23 | 陆振雄 | A kind of production method of the medicine of burning |
| CN1107733A (en) * | 1994-12-02 | 1995-09-06 | 李钧 | Heat-clearing and detoxifying drug for external use |
| CN1127129A (en) * | 1995-01-16 | 1996-07-24 | 徐永林 | External application medicine for burn and scald and preparing method |
| CN1116539A (en) * | 1995-04-24 | 1996-02-14 | 刘景文 | Burn and scald curing ointment |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1178109A (en) | 1998-04-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1055297A (en) | A kind of autofrettage of skin-moistening burn and scald medicine | |
| CN1593540A (en) | Ointment for treating burns and scalds and its preparation | |
| CN1695694A (en) | Chinese traditional medicine for treating breast disease and preparing technique | |
| CN1723931A (en) | Cure-all ointment for treating burns and scald | |
| CN1813955A (en) | Medicine for treating tympanitis and otitis externa, and preparing method | |
| CN103316315B (en) | Cooling paste | |
| CN1341435A (en) | Wound quick healing ointment | |
| CN1058620C (en) | Yingfengaidi medicine and its production process | |
| CN1064540C (en) | Medicine for burn and scald | |
| CN102119975B (en) | Chinese herbal medicine ointment for treating ulcer, bedsore and vascular dermatoses | |
| CN1322554A (en) | Cream for treating burns, scalds and sore ulcer and its preparation | |
| CN1279952C (en) | Medicine for treating burns and scalds | |
| CN1293897C (en) | Burn and scald treating powder | |
| CN1215595A (en) | External use medicine for treating soft tissue injury and its producing method | |
| CN1476868A (en) | Ointment for external application for curing scald and burn | |
| CN101032333A (en) | Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa | |
| CN1175850C (en) | Medicine for treating burns and scald, and producing method thereof | |
| CN1172701C (en) | Medicine for curing herpes zoster | |
| CN1186050C (en) | Ointment for removing necrosis, promoting granulation and invigorating bone and its prepn | |
| CN107050302A (en) | Treat the external application Chinese medicine of burn and scald | |
| CN1313117C (en) | Chinese medicine external applied powder for bone damage | |
| CN1150016C (en) | Medicine for treating fever caused by lupus erythematosus and other immunological disease | |
| CN1927369A (en) | Medicine for curing burn and scald wound and its preparation method | |
| CN101095752B (en) | Chinese traditional medicine for treating burn and scald | |
| CN1123348C (en) | Capsule for treating rheumatic and rheumatoid arthritis and its preparing process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |