CN1483805A - 一种用于动物细胞扩大接种的消化反应器 - Google Patents
一种用于动物细胞扩大接种的消化反应器 Download PDFInfo
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- CN1483805A CN1483805A CNA021370699A CN02137069A CN1483805A CN 1483805 A CN1483805 A CN 1483805A CN A021370699 A CNA021370699 A CN A021370699A CN 02137069 A CN02137069 A CN 02137069A CN 1483805 A CN1483805 A CN 1483805A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
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- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
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- Biotechnology (AREA)
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- General Health & Medical Sciences (AREA)
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Abstract
Description
Claims (5)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB021370699A CN1300297C (zh) | 2002-09-20 | 2002-09-20 | 一种用于动物细胞扩大接种的消化反应器 |
US10/455,136 US20040058436A1 (en) | 2002-09-20 | 2003-06-05 | Cell-detaching reactor for scaled-up inoculation of anchorage-dependent cell culture |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB021370699A CN1300297C (zh) | 2002-09-20 | 2002-09-20 | 一种用于动物细胞扩大接种的消化反应器 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1483805A true CN1483805A (zh) | 2004-03-24 |
CN1300297C CN1300297C (zh) | 2007-02-14 |
Family
ID=31983686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB021370699A Expired - Fee Related CN1300297C (zh) | 2002-09-20 | 2002-09-20 | 一种用于动物细胞扩大接种的消化反应器 |
Country Status (2)
Country | Link |
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US (1) | US20040058436A1 (zh) |
CN (1) | CN1300297C (zh) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102766575A (zh) * | 2011-05-04 | 2012-11-07 | 苏州勃朗科技有限公司 | 一种动物细胞发酵分离一体机 |
CN105037535A (zh) * | 2008-12-16 | 2015-11-11 | Emd密理博公司 | 搅拌槽反应器及方法 |
CN105238689A (zh) * | 2015-09-29 | 2016-01-13 | 中牧实业股份有限公司 | 一种吹打细胞的装置及基于其的细胞传代培养方法 |
CN106754366A (zh) * | 2017-04-05 | 2017-05-31 | 苏州迪欧益生物科技有限公司 | 用于动物细胞培养的一次性智能消化器系统 |
CN107400632A (zh) * | 2017-08-14 | 2017-11-28 | 广州齐志生物工程设备有限公司 | 一种细胞消化放大装置 |
CN107974399A (zh) * | 2017-12-27 | 2018-05-01 | 北京科兴生物制品有限公司 | 一种细胞消化器 |
US10233211B2 (en) | 2006-12-21 | 2019-03-19 | Emd Millipore Corporation | Purification of proteins |
US10793593B2 (en) | 2006-12-21 | 2020-10-06 | Emd Millipore Corporation | Purification of proteins |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050287670A1 (en) * | 2004-06-29 | 2005-12-29 | Gulliver Eric A | Cell culturing systems, methods and apparatus |
US8603805B2 (en) | 2005-04-22 | 2013-12-10 | Hyclone Laboratories, Inc. | Gas spargers and related container systems |
FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
US9845455B2 (en) * | 2008-05-15 | 2017-12-19 | Ge Healthcare Bio-Sciences Ab | Method for cell expansion |
DE102009022352A1 (de) * | 2009-05-15 | 2010-11-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Ablöseverfahren für adhärente Zellen |
WO2011047900A2 (en) | 2009-10-22 | 2011-04-28 | Glaxosmithkline Biologicals S.A. | Novel process |
EP3597671B1 (en) | 2010-05-17 | 2022-09-21 | EMD Millipore Corporation | Stimulus responsive polymers for the purification of biomolecules |
US9376655B2 (en) | 2011-09-29 | 2016-06-28 | Life Technologies Corporation | Filter systems for separating microcarriers from cell culture solutions |
US9643133B2 (en) | 2011-09-30 | 2017-05-09 | Life Technologies Corporation | Container with film sparger |
US10781417B2 (en) | 2012-12-11 | 2020-09-22 | Pall Technology Uk Limited | System and method for detachment of cells in fixed bed reactors |
US9079690B1 (en) | 2014-06-26 | 2015-07-14 | Advanced Scientifics, Inc. | Freezer bag, storage system, and method of freezing |
JP2016036274A (ja) * | 2014-08-06 | 2016-03-22 | 株式会社Ihi | 細胞剥離方法、細胞剥離装置、及び、細胞培養システム |
JP6858713B2 (ja) * | 2015-05-29 | 2021-04-14 | メゾブラスト・インターナショナル・エスアーエールエル | 細胞をマイクロキャリアから分離するための方法及び装置 |
US10589197B2 (en) | 2016-12-01 | 2020-03-17 | Life Technologies Corporation | Microcarrier filter bag assemblies and methods of use |
CN112143651B (zh) * | 2020-10-13 | 2024-04-19 | 南京金日轻工科技发展有限公司 | 一种用于细胞培养的一体式旋转搅拌过滤器 |
WO2022254039A1 (en) * | 2021-06-03 | 2022-12-08 | Univercells Technologies Sa | Bioreactor system with enhanced cell harvesting capabilities and related methods |
CN113980799A (zh) * | 2021-10-26 | 2022-01-28 | 陈福春 | 一种微生物细菌培养繁殖用接种仪 |
CN114657118B (zh) * | 2021-12-31 | 2023-12-01 | 广州齐志生物工程设备有限公司 | 一种2bs细胞在生物反应器内的多倍放大方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
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US4664912A (en) * | 1984-10-01 | 1987-05-12 | Wiktor Tadeusz J | Process for the large scale production of rabies vaccine |
US5223429A (en) * | 1986-06-16 | 1993-06-29 | Slobodan Tepic | Method for the mass growth of cells in a thin film of nutrient medium foam |
DE3739649A1 (de) * | 1987-11-23 | 1989-06-22 | Immuno Ag | Verfahren zum abloesen von zellkulturen von mikrotraegern |
US5079161A (en) * | 1988-06-27 | 1992-01-07 | Snow Brand Milk Products Co., Ltd. | Method and apparatus for cell culture with immobilizing carriers |
US6188460B1 (en) * | 1990-06-11 | 2001-02-13 | Reveo, Inc. | Image display panel having a backlighting structure and a single-layer pixelated aray of reflective-type spectral filtering elements where between light is recycled for producing color images with enhanced brightness |
US5240856A (en) * | 1991-10-23 | 1993-08-31 | Cellpro Incorporated | Apparatus for cell separation |
IL104385A (en) * | 1992-01-17 | 1995-12-31 | Applied Research Systems | Method and device for growing biomass particles |
FR2690926B1 (fr) * | 1992-05-06 | 1995-08-04 | Lvmh Rech | Dispositif du type reacteur a volume variable et procede de culture cellulaire. |
GB9625301D0 (en) * | 1996-12-05 | 1997-01-22 | Smith & Nephew | Cell-culture system |
US6146891A (en) * | 1997-01-31 | 2000-11-14 | Schering Corporation | Methods for cultivating cells and propagating viruses |
CN1126001C (zh) * | 1997-02-13 | 2003-10-29 | 联合讯号公司 | 具有光循环以增强亮度的照明系统 |
US6001642A (en) * | 1998-06-29 | 1999-12-14 | Wyle Laboratories, Inc. Life Sciences | Bioreactor and cell culturing processes using the bioreactor |
US6325524B1 (en) * | 1999-01-29 | 2001-12-04 | Agilent Technologies, Inc. | Solid state based illumination source for a projection display |
US6364487B1 (en) * | 1999-01-29 | 2002-04-02 | Agilent Technologies, Inc. | Solid state based illumination source for a projection display |
GB9905646D0 (en) * | 1999-03-11 | 1999-05-05 | Cobra Therapeutics Ltd | A vessel for mixing a cell lysate |
ATE275625T1 (de) * | 2000-07-19 | 2004-09-15 | Technodop Ltd Soc De Droit Irl | Kulturraum und bioreaktor zur ausserkörperlichen tierzellenkultur |
-
2002
- 2002-09-20 CN CNB021370699A patent/CN1300297C/zh not_active Expired - Fee Related
-
2003
- 2003-06-05 US US10/455,136 patent/US20040058436A1/en not_active Abandoned
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10233211B2 (en) | 2006-12-21 | 2019-03-19 | Emd Millipore Corporation | Purification of proteins |
US10793593B2 (en) | 2006-12-21 | 2020-10-06 | Emd Millipore Corporation | Purification of proteins |
CN105037535A (zh) * | 2008-12-16 | 2015-11-11 | Emd密理博公司 | 搅拌槽反应器及方法 |
CN102766575A (zh) * | 2011-05-04 | 2012-11-07 | 苏州勃朗科技有限公司 | 一种动物细胞发酵分离一体机 |
CN105238689A (zh) * | 2015-09-29 | 2016-01-13 | 中牧实业股份有限公司 | 一种吹打细胞的装置及基于其的细胞传代培养方法 |
CN106754366A (zh) * | 2017-04-05 | 2017-05-31 | 苏州迪欧益生物科技有限公司 | 用于动物细胞培养的一次性智能消化器系统 |
CN107400632A (zh) * | 2017-08-14 | 2017-11-28 | 广州齐志生物工程设备有限公司 | 一种细胞消化放大装置 |
CN107974399A (zh) * | 2017-12-27 | 2018-05-01 | 北京科兴生物制品有限公司 | 一种细胞消化器 |
Also Published As
Publication number | Publication date |
---|---|
US20040058436A1 (en) | 2004-03-25 |
CN1300297C (zh) | 2007-02-14 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Shanghai RAAS Blood Products Co., Ltd. Assignor: East China University of Science and Technology Contract fulfillment period: 2008.9.26 to 2016.9.25 contract change Contract record no.: 2008990000524 Denomination of invention: Digestive reactor for animal cell extension inoculation Granted publication date: 20070214 License type: Exclusive license Record date: 2008.10.6 |
|
LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.9.26 TO 2016.9.25; CHANGE OF CONTRACT Name of requester: SHANGHAI LAISHI BLOOD PRODUCT CO., LTD. Effective date: 20081006 |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070214 Termination date: 20160920 |