CN1478042A - Disposable package for volatile liquid - Google Patents

Disposable package for volatile liquid Download PDF

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Publication number
CN1478042A
CN1478042A CNA018198147A CN01819814A CN1478042A CN 1478042 A CN1478042 A CN 1478042A CN A018198147 A CNA018198147 A CN A018198147A CN 01819814 A CN01819814 A CN 01819814A CN 1478042 A CN1478042 A CN 1478042A
Authority
CN
China
Prior art keywords
liquid
cover
liquid vessel
face
packing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA018198147A
Other languages
Chinese (zh)
Inventor
M・贾维斯
M·贾维斯
克
R·斯塔克
K·巴茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Ltd
Procter and Gamble Co
Original Assignee
Procter and Gamble Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Ltd filed Critical Procter and Gamble Ltd
Publication of CN1478042A publication Critical patent/CN1478042A/en
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • B65D51/22—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing having means for piercing, cutting, or tearing the inner closure
    • B65D51/221—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing having means for piercing, cutting, or tearing the inner closure a major part of the inner closure being left inside the container after the opening
    • B65D51/222—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing having means for piercing, cutting, or tearing the inner closure a major part of the inner closure being left inside the container after the opening the piercing or cutting means being integral with, or fixedly attached to, the outer closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0006—Upper closure
    • B65D2251/0025—Upper closure of the 47-type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0068—Lower closure
    • B65D2251/0093—Membrane

Abstract

The present invention relates to an improved package, suitable for holding a treatment fluid comprising a volatile solvent. The package (1) comprises a reservoir (2) for the liquid which is sealed by a rupturable seal (7). A cap (3), coupled to one end of the reservoir, is the form of a sleeve which is axially translatable along the reservoir from first to second positions. A cutting tool (17) integrated with the cap ruptures the rupturable seal as the cap is moved from first to second positions so that the liquid can thereby be made accessible through an opening in an end wall of the cap. The package provides excellent protection for volatile liquids, yet can be easily opened by a simple press-action, instantly providing access to the liquid so that it can subsequently accessed by a liquid applicator. Also disclosed are kits comprising the package and an applicator and/or treatment fluid.

Description

A kind of non-returnable container that is used for volatile liquid
Technical field
The present invention relates to a kind of liquid that is used for, in particular for the non-returnable container of the volatility film forming liquid of dental care.
Background technology
Now people more and more requirement can nurse oneself tooth, except brushing teeth with cleaning products traditionally, for example also available tooth whitening products.A kind of exemplary dental whitening compositions is open in PCT application WO 01/01940, and this application is incorporated herein by reference.
Disclosed nursing fluid only is the example in many effective fluid compositions in the PCT application of above quoting, these effective fluid compositions comprise dissolving or are dispersed in film forming polymer in the volatile solvent, this volatile solvent is applied subsequently, for example is applied on the nursing surface to be nursed.The problem that this class fluid brings is that a kind of packing easily need be provided, and this packing can prevent fluid drying, but still can use easily when needed.
Therefore, a target of the present invention is to provide a kind of disposable packing for volatile film forming liquid.Further target of the present invention is the sealed package that a kind of easy unlatching and use are provided for liquid.The present invention further target provides packing cheap for manufacturing cost.
These and other target will become very obvious by following detailed.
The sealed ampoule that is used for flexible package punch can recognize from for example German utility model patent DE 92 02 654 U1, this patent disclosure a kind ofly can push the ampoule of opening and hairbrush can being inserted wherein.Described a kind of ampoule of multiple chamber among the patent WO98/53789, this ampoule has first and second cylindrical containers, and they mate coaxially to each other together and are telescopiforms.
Described a kind of automatically cleaning immersion packing that is used for liquid among the patent WO 00/41588, wherein liquid comprises volatile solvent and film-forming resin.
The invention provides a kind of packing that comprises a liquid vessel, wherein liquid is by a rupturable sealing sealing.A cover that is connected on liquid vessel one end face adopts the form of sleeve pipe, and this sleeve pipe can be coaxial mobile to the second place by primary importance along liquid vessel.When cover moved to the second place by primary importance, a cutting tool that integrates with cover isolated rupturable sealing, thereby the opening of liquid on can facing the wall and meditating by an end of cover circulated.
Summary of the invention
The invention provides a kind of packing that is used for liquid, this packing comprises:
A) liquid vessel that comprises sidewall, this sidewall have an outside face and are arranged on first and second end faces of the longitudinal axis opposite end surface of liquid vessel, and first end face has defined one by rupturable sealing sealed opening, and second end face is sealed; With
B) cover, it is with a kind of form of sleeve pipe, is connected on first end face of liquid vessel coaxially and a longitudinal axis public with liquid vessel is arranged, and this cover can be moved axially to the second place by primary importance along the longitudinal axis of liquid vessel, and comprises:
(i) have a sidewall of an inside face, this inside face can with the outside face frictional engagement of liquid vessel sidewall together;
(ii) by first and second end faces that define of sidewall of cover, first end face is connected on first end face of liquid vessel the first and second two positions, second end face comprises a cover end wall, this cover end wall and liquid vessel are in second place adjacency, the cover end wall comprises an opening, when rupturable sealing was isolated, the liquid in the liquid vessel can be by this opening circulation; With
(iii) one dangles at the cutting tool that covers on the end wall, and when cover moved to the second place vertically by primary importance, cutting tool just isolated rupturable sealing, thereby liquid can be circulated by the opening of cover end wall.
Package design disclosed herein provides good protection for volatile liquid, yet also can easily open by simple pressing operation, and packing is once opening the passage that offers liquid communication rapidly, and liquid can be used by a kind of applicator contact so subsequently.
The invention further relates to the complete articles for use that comprise packing, an applicator and/or nurse fluid.
Summary of drawings
Fig. 1 is the transparent view of packing as described herein, to approach the actual size drafting and to show its longitudinal axis;
Fig. 2 is an exploded view, more clearly illustrates liquid vessel and cover;
Fig. 3 is the local longitdinal cross-section diagram that passes cover, illustrates cutting tool;
Fig. 4 be pass packing, its primary importance (as assemble) local longitdinal cross-section diagram;
Fig. 5 be pass packing, at the local longitdinal cross-section diagram of its second place, after sealing is isolated, can obtain to pack interior liquid (not shown) by a kind of applicator (part diagram);
Fig. 6 is a transparent view of replacing embodiment of cover.
Fig. 7 is the local longitdinal cross-section diagram that passes the packing of further embodiment, illustrates a kind of improved cutting tool and liquid vessel sidewall.
Concrete embodiment
Reach by one embodiment of the invention now and be described in greater detail with reference to the accompanying drawings.
Packing 1 is cylindrical shape normally, and it comprises a liquid vessel 2 (being used to store a kind of liquid) and cover 3.But liquid vessel and cover are preferably made by injection moulding by rubber-like, the plastic product of checking and approving contact food (FDA) grade.Other material such as aluminium also can use.Suitable plastic product comprises COC, polypropylene, polyethylene, nylon, polyacetal, acrylonitrile materials such as Barex And polycarbonate.Preferred plastic product is a polypropylene.
Liquid vessel 2 comprises a sidewall 4, and this sidewall 4 has an outside face and is in first and second end faces (5 and 6) of liquid vessel both ends of the surface, and first end face has defined one by rupturable sealing 7 sealed opening, and second end face is sealed.Although in this embodiment, be circular perpendicular to the cross-sectional plane of this packing longitudinal axis, this is not critical, cross-sectional plane can be for example square, triangle or oval-shaped.Although also can use laminated material, sealing is preferably made by the individual layer aluminium foil.Thereby the paper tinsel sealing is to apply a side with a kind of lacquer liquid vessel can be heat-sealed.Seal thickness is preferably about 15 to about 50 microns scope, more preferably about 20 microns.On first end face of sealing attached to liquid vessel, but when with complete closed liquid vessel opening after the liquid filling that requires.Preferably, for example adopt conduction or high-frequency heating, will seal attached on the end face by heat-sealable way.The outside face of liquid vessel sidewall comprises first groove 8 and second groove 9, and these two grooves have defined first and second positions on the liquid vessel.
Encasement 3 adopts a kind of form of sleeve pipe, and this sleeve pipe has one to match with the cross-sectional plane of liquid vessel with the public longitudinal axis and the cross-sectional plane of liquid vessel, and its cross-sectional plane is a circle in this example.Cover comprises a sidewall 10 with inside face 11, outside face 4 frictional engagement of this inside face 11 and liquid vessel sidewall, and this cover can be moved to the second place by primary importance along the longitudinal axis of liquid vessel.
The internal table face of cover sidewall comprises lug 12, and this lug has guaranteed the frictional engagement with liquid vessel sidewall outside face 4.Lug is connected in primary importance with first groove, but allows to cover the second place that moves on the liquid vessel.Lug and groove part are bevelled, just as shown in Figures 4 and 5, have prevented preferably in a single day assembling back cover is moved.Groove and lug engagement have formed stabilizing device, and this device had not only guaranteed to cover a kind of feedback information of user that is fixed on the liquid vessel but also offers packing, illustrate that packing has been on the tram of first and second positions.Lug is arranged in around the surface, inside of cover sidewall, can be to be spaced or to form a kind of ring-shaped continuous at a certain distance.In the embodiment that provides, on the scalloped edge that bottom (second) end face of cover is given prominence to, there are four lugs to arrange at interval downwards with 90 °.Lug placed help on these extrusion positions outwards to promote lug when being assembled on the liquid vessel when cover.The size of remainder of cover allows little gap, and for example the gap between the outside face of cover inner surface and liquid vessel sidewall is about 0.1 millimeter, makes the cooperation of cover can be too not tight like this.This gap is can not be too big otherwise reduction is covered on stability on the liquid vessel.Similarly, for the stability that guarantees to cover, the position of crew-served lug and groove should make and guarantee liquid vessel and cover overlapping substantially when the primary importance of its assembling.
Cover further comprises first and second end faces (13 and 14) that defined by the sidewall that covers.First end face of cover is connected on first end face of liquid vessel the first and second two positions, and cover has a crenate profile, as discussed above and just as shown in Figure 2.Second end face of cover comprises a cover end wall 15, and first end face of this end wall and liquid vessel is in second place place adjacency.The cover end wall comprises an opening 16, and the liquid when rupturable sealing 7 is isolated in the liquid vessel 2 can be by this opening circulation.
A cutting tool 17, together Unitarily molded with the form of cutter with cover end wall 15, and dangle on it.When sleeve pipe by primary importance when the second place is mobile vertically, cutting tool isolates rupturable sealing, thereby makes the liquid can be by opening 16 circulation of cover end wall.Just as shown in Figure 4, cutting tool forms a cylindrical chamfered portion, thereby it also can be pushed into both sides with sealing when instrument was cut rupturable sealing, thereby the liquid in the packing can easily be circulated.Although cutting tool may adopt multiple shape, but cut and level and smooth opening in order to guarantee neat cutter, preferred kit has a kind of like this shape, and when covering by primary importance when the second place advances, this shape can make only to have on the blade a bit and cut on the leak free at a point in time.The further advantage of describing in this embodiment that cutting tool had is that the sealing meeting is rolled after cutting tool when sealing is cut, thereby has avoided sealing and applicator mutual interference mutually subsequently.
By foregoing as can be seen, this packing only comprises two different parts, promptly covers and liquid vessel, and the two all is easy to molding and is easy to assemble up by cover is pressed onto on the liquid vessel.If desired, liquid vessel can be in an inclined-plane co-operating that has on its first end face on an antelabium and the cover, in case to prevent that packing assembling back cover from coming off.When being in confined state, simply pushing action for one just is enough to cover is moved to the second place on the liquid vessel, thereby isolates sealing.Packing is enough cheap, in case use the back just discardable.A kind of preferable methods that obtains liquid is by a kind of applicator 18, and this applicator 18 all can be included in the complete articles for use of a cover with packing.Applicator generally includes a tip 19, and this tip can be for example a kind of hairbrush, a kind of flocked applicator or a kind of cavernous body.Preferred applicator tip is a kind of nylon bristle.
Cover 3 can further comprise mark 20 on the outside face of its sidewall, illustrate that with the user to packing cover is to move to the second place by primary importance, and for example vertical rib 21 of explanation protrusion is the auxiliary covers of holding.This class rib also can comprise horizontal rib.
Fig. 7 has illustrated a preferred further embodiment, and the feature that this embodiment has helps to make reliably and open packing.In the embodiment of Fig. 7, liquid vessel sidewall 4 ' all has a chamfering 22 on the inside and outside surface of first end face 5 ' of liquid vessel.This can guarantee that when rupturable sealing is sealed to first end face of liquid vessel the pearl that the local melting of liquid vessel sidewall can not cause generating extends to the coupling of also disturbing cover outside the sidewall.And cutting tool 17 ' also has a chamfering 23 at its bottom end face place, and this chamfering can be assisted and be opened packing.When cover was pressed towards its second place, chamfering 23 can guarantee guide cuts instrument 17 ' through liquid vessel sidewall 4 ', and the motion of not covering by first end face interference of adjacency liquid vessel sidewall hinders being moved further of cover.
The part that this packing can be used as complete articles for use provides, these complete articles for use comprise packing and a kind of or liquid care composition (being preferably a kind of dental whitening compositions) is preferably arranged simultaneously and be used for the applicator (for example a kind of hairbrush) of said composition, can be randomly with description of operation together.Care composition can be pure cosmetics, and for example lip cosmetic or mascara, or also can be a kind of medical composition for example a kind ofly be used to strengthen dental care Remineralising composition tooth glaze or a kind of preventing decayed tooth or desensitization.Preferred liquid care composition comprises that a kind of boiling point is lower than 200 ℃ organic solvent.A kind of preferred liquid care composition is a kind of dental whitening compositions that further comprises bleaching agent.Exemplary cosmetics nursing thing, especially dental whitening compositions provide in PCT application WO01/01940, and this application is incorporated herein by reference.
In fact packing of the present invention is as disposable product, thereby very little usually.Liquid vessel cumulative volume in the graphic embodiment is about 0.6 milliliter, and about 0.3 milliliter care composition is housed usually.Certainly should select actual size according to special-purpose.When the amount of applicating liquid composite in the applied once process is relatively large, or open that packing back composite can store and when obviously not rotten, for example, use sizable size to suit to the situation of non-volatile solvents, for example can be or even 100 milliliters up to 10 milliliters.
Because content of the present invention disclosed herein can not deviate from essential characteristic of the present invention with other concrete form enforcement, so it only is illustrative that embodiment described herein should be interpreted as fully, scope of the present invention is pointed out in accessory claim rather than is pointed out in the foregoing description; And be included in the present invention in the meaning of the equivalent of claim and all embodiments in the scope.For example, in described embodiment, cover moves along the liquid vessel straight line.Yet cover also can be screwed on the liquid vessel by screw thread, and this like this moving just has revolving property.Equally, cover can be introduced parts to connect a kind of applicator, for example in the mode described in the WO98/53789.

Claims (10)

1. packing (1) that is used for liquid, this packing comprises:
A) liquid vessel (2), it comprises a sidewall (4,4 '), this sidewall has an outside face and is arranged at first and second end faces (5 of the opposite end surface of the liquid vessel longitudinal axis, 5 ', 6), first end face has defined one by rupturable sealing (7) sealed opening, and second end face is sealed; With
B) cover (3), with a kind of form of sleeve pipe, first end face (5,5 ') that is connected to liquid vessel is coaxially gone up and a longitudinal axis public with liquid vessel is arranged, and cover can be along axially being moved to the second place by primary importance of liquid vessel, and it comprises:
(i) have the sidewall (10) of an inside face (11), this inside face can with the outside face frictional engagement of liquid vessel sidewall (4,4 ') together;
(ii) by first and second end faces (13 of the sidewall definition of cover, 14), first end face (13) is connected simultaneously first end face (5 of liquid vessel the first and second two positions, 5 ') on, second end face comprises a cover end wall (15), and this cover end wall and liquid vessel are in second place adjacency, and the cover end wall comprises an opening, when rupturable sealing (7) was isolated, the liquid in the liquid vessel can be by this opening circulation; And
(iii) one dangles at the cutting tool (17,17 ') that covers on the end wall, and therefore when cover (3) moved to the second place by primary importance is coaxial, cutting tool isolated rupturable sealing (7), thereby liquid can be circulated by the opening of cover end wall.
2. packing as claimed in claim 1 is characterized in that, liquid vessel and cover have the circular cross section perpendicular to the longitudinal axis.
3. packing as claimed in claim 1 or 2 is characterized in that, the outside face of liquid vessel sidewall comprises one first groove (8), the cover inside surface of side wall comprise with first groove at primary importance bonded assembly lug (12).
4. packing as claimed in claim 3 is characterized in that, the outside face of liquid vessel sidewall comprise one second groove (9) and with second groove at second place bonded assembly lug (12).
5. the described packing of arbitrary as described above claim, it is characterized in that, cutting tool is a kind of and cover end wall Unitarily molded cutter together, and preferred cutting tool has a chamfering 23 to conflict with liquid vessel sidewall (4,4 ') avoiding at an one bottom end face place.
6. the described packing of arbitrary as described above claim is characterized in that, comprises a kind of liquid care composition that is sealed in the liquid vessel, and this care composition comprises that a kind of boiling point is lower than 200 ℃ organic solvent.
7. packing as claimed in claim 6 is characterized in that, the liquid care composition is a kind of dental whitening compositions that further comprises bleaching agent.
8. one overlaps complete articles for use, and it comprises:
A) the described packing of arbitrary as described above claim;
B) a kind of liquid care composition that is sealed in the liquid vessel, this care composition comprises that a kind of boiling point is lower than 200 ℃ organic solvent.
C) applicator (18) that is used for the liquid care composition, when packing was in its second place, this applicator can be inserted in the liquid care composition by the opening of cover end wall.
9. complete articles for use as claimed in claim 8 is characterized in that, the liquid care composition is a kind of dental whitening compositions that further comprises bleaching agent.
10. complete articles for use as claimed in claim 8 is characterized in that, the tip (19) of applicator (18) is a kind of nylon bristle.
CNA018198147A 2000-12-01 2001-11-30 Disposable package for volatile liquid Pending CN1478042A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0029354.8 2000-12-01
GB0029354A GB0029354D0 (en) 2000-12-01 2000-12-01 A disposable package for a volatile liquid

Publications (1)

Publication Number Publication Date
CN1478042A true CN1478042A (en) 2004-02-25

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ID=9904275

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Application Number Title Priority Date Filing Date
CNA018198147A Pending CN1478042A (en) 2000-12-01 2001-11-30 Disposable package for volatile liquid

Country Status (8)

Country Link
EP (1) EP1337445A2 (en)
JP (1) JP2004518588A (en)
CN (1) CN1478042A (en)
CA (1) CA2427524A1 (en)
GB (1) GB0029354D0 (en)
MX (1) MXPA03004872A (en)
PL (1) PL361953A1 (en)
WO (1) WO2002060779A2 (en)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
JP2005537308A (en) * 2002-08-15 2005-12-08 ザ プロクター アンド ギャンブル カンパニー How to whiten teeth
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
JP3956294B2 (en) * 2002-11-27 2007-08-08 富士レビオ株式会社 Prevention method for reagent container cap and reagent evaporation
EP1923705A4 (en) 2005-08-10 2014-11-05 Beckman Coulter Inc Seal member, cap of reagent container, and reagent container
US8016104B2 (en) * 2005-10-25 2011-09-13 Biogaia Ab Two-compartment container having depressible flexible dome for rupturing layer between compartments
JP4861787B2 (en) * 2006-10-10 2012-01-25 シスメックス株式会社 Reagent container and reagent container holder
JP5272205B2 (en) * 2007-09-25 2013-08-28 和光純薬工業株式会社 Reagent container
EP2096046B1 (en) * 2008-02-27 2011-03-30 Arnold Jahn Drink bottle and system for creating a mixed drink

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US3580423A (en) * 1969-02-27 1971-05-25 Realistic Co Container closure and apparatus for opening same
US3676076A (en) * 1970-09-24 1972-07-11 Gradko Glass Lab Inc Disposable container
FR2165782B1 (en) * 1971-12-27 1974-08-30 Lincrusta
DE9202654U1 (en) 1992-02-28 1992-04-23 Sogaro Vertrieb Und Verwaltung, 6380 Bad Homburg, De
DE19722765A1 (en) 1997-06-01 1998-12-03 Dentaco Gmbh Multi-chamber ampoule
DE29802038U1 (en) * 1998-02-06 1998-04-02 Georg Menshen Gmbh & Co Kg Arrangement of pouring-welded part and hose connection device
US6276856B1 (en) 1999-01-12 2001-08-21 The Procter & Gamble Company Self cleaning dip-in package for liquids
ATE292953T1 (en) * 1999-07-02 2005-04-15 Procter & Gamble COMPOSITIONS CONTAINING ORGANOSILOXANE RESINS FOR THE RELEASE OF ORAL CARE INGREDIENTS
AU782107B2 (en) * 1999-11-17 2005-07-07 Fredrick Michael Coory Piercing cap for a container
WO2001074291A1 (en) * 2000-04-04 2001-10-11 Otsuka Pharmaceutical Factory, Inc. Liquid container and liquid container connecting body using the liquid container

Also Published As

Publication number Publication date
MXPA03004872A (en) 2003-08-19
JP2004518588A (en) 2004-06-24
EP1337445A2 (en) 2003-08-27
WO2002060779A3 (en) 2002-10-17
PL361953A1 (en) 2004-10-18
WO2002060779A2 (en) 2002-08-08
CA2427524A1 (en) 2002-08-08
WO2002060779A8 (en) 2004-02-12
WO2002060779A9 (en) 2003-02-13
GB0029354D0 (en) 2001-01-17

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