CN1470531A - 以组蛋白为核心序列的靶向性基因导入系统 - Google Patents

以组蛋白为核心序列的靶向性基因导入系统 Download PDF

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Publication number
CN1470531A
CN1470531A CNA021361622A CN02136162A CN1470531A CN 1470531 A CN1470531 A CN 1470531A CN A021361622 A CNA021361622 A CN A021361622A CN 02136162 A CN02136162 A CN 02136162A CN 1470531 A CN1470531 A CN 1470531A
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CN
China
Prior art keywords
lys
histone
ala
gene
pro
Prior art date
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Pending
Application number
CNA021361622A
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English (en)
Chinese (zh)
Inventor
顾健人
杨胜利
龚毅
朱景德
陈燕
戴菲寒
任常青
田培坤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANGHAI XINSHIJIE GENE TECHN DEVELOPMENT Co Ltd
Original Assignee
SHANGHAI XINSHIJIE GENE TECHN DEVELOPMENT Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANGHAI XINSHIJIE GENE TECHN DEVELOPMENT Co Ltd filed Critical SHANGHAI XINSHIJIE GENE TECHN DEVELOPMENT Co Ltd
Priority to CNA021361622A priority Critical patent/CN1470531A/zh
Priority to AU2002327321A priority patent/AU2002327321A1/en
Priority to PCT/CN2002/000592 priority patent/WO2004009811A1/fr
Publication of CN1470531A publication Critical patent/CN1470531A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
CNA021361622A 2002-07-24 2002-07-24 以组蛋白为核心序列的靶向性基因导入系统 Pending CN1470531A (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CNA021361622A CN1470531A (zh) 2002-07-24 2002-07-24 以组蛋白为核心序列的靶向性基因导入系统
AU2002327321A AU2002327321A1 (en) 2002-07-24 2002-08-26 A gene entrain system with the core sequence of histone
PCT/CN2002/000592 WO2004009811A1 (fr) 2002-07-24 2002-08-26 Systeme d'entrainement de genes comprenant une sequence de noyau d'histone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA021361622A CN1470531A (zh) 2002-07-24 2002-07-24 以组蛋白为核心序列的靶向性基因导入系统

Publications (1)

Publication Number Publication Date
CN1470531A true CN1470531A (zh) 2004-01-28

Family

ID=30121787

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA021361622A Pending CN1470531A (zh) 2002-07-24 2002-07-24 以组蛋白为核心序列的靶向性基因导入系统

Country Status (3)

Country Link
CN (1) CN1470531A (fr)
AU (1) AU2002327321A1 (fr)
WO (1) WO2004009811A1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181422A (zh) * 1996-10-31 1998-05-13 上海市肿瘤研究所 与生长因子受体结合的多肽所构建的基因转移载体

Also Published As

Publication number Publication date
WO2004009811A1 (fr) 2004-01-29
AU2002327321A1 (en) 2004-02-09

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