CN1465245A

CN1465245A - Built disinfectant

Info

Publication number: CN1465245A
Application number: CNA021378843A
Authority: CN
Inventors: 吴进才; 黄奔立
Original assignee: 周耀德
Current assignee: Jiangsu Sevencontinent Green Chemical Co Ltd
Priority date: 2002-06-30
Filing date: 2002-06-30
Publication date: 2004-01-07
Anticipated expiration: 2022-06-30
Also published as: CN1223269C

Abstract

The present invention relates to a mycocidal compounded pesticide preparation for curing grey mould of plants of vegetables and fruits. It is made of (wt%) 1-50% of procymidone and 0.5-10% of hexaconazole, and can obtain good effect.

Description

A kind of built disinfectant

Technical field

The present invention relates to a kind ofly to be applicable to plants such as vegetables, fruit, in order to prevent and treat the built disinfectant of gray mold.

Background technology

Along with the adjustment of the structure of rural undertaking, the planting proportion of economic crops has had and has increased considerably, and particularly the amplification of the cultivated area of vegetables, fruit is particularly evident.Gray mold is one of important disease of vegetables, fruit, and diseased plant rate is generally 15～30%, and serious reaches 40～50%, causes shedding, decayed fruit, causes very big loss to agricultural production.

In agricultural production, have: thiophanate methyl, carbendazim, tmtd, Sukeling, Pola peace, iprodione, Shi Jiale etc. in order to the medicament commonly used of preventing and treating gray mold.But it is relatively poor to the preventive effect of gray mold as thiophanate methyl, carbendazim, tmtd, Pola peace etc. that these medicines have, what have is higher as agricultural chemicals costs such as Sukeling, iprodione, Shi Jiale, and single agent kind ubiquity resistance risk, can make the medicament reduction or lose preventive effect.

Summary of the invention

At the problems referred to above, the present invention will provide that a kind of control efficiency is good, cost is lower, and the effective built disinfectant that takes place of delaying drug resistance.

The main technical schemes that the present invention adopts is: with the own azoles alcohol in the triazole bactericidal agent of procymidone and efficient, low toxicity, low resistance risk is active princlple, is mixed with a kind of built disinfectant.

The procymidone of one of effective ingredient of the present invention, the trade name Sukeling, chemical name: N-(3, the 5-dichlorophenyl)-1,3-dimethylcyclopropane-1, the 2-di carbonyl imide, structural formula is:

The own azoles alcohol of another effective ingredient of the present invention, chemical name: (RS)-and 2-(2,4 dichloro benzene base)-1-(1H-1,2,4-triazol-1-yl)-hexanol-2, structural formula is:

Built disinfectant of the present invention, its active princlple include the own azoles alcohol of procymidone and triazole bactericidal agent, and in whole composite dose, the weight percent content of procymidone is 1～50%, and the weight percent content of own azoles alcohol is 0.5～10%.

The further technical scheme of the present invention is: the weight percent content of procymidone more preferably 5～20% in described composite dose, the weight percent content of own azoles alcohol more preferably 0.5～5%.

Composite dose of the present invention can if desired, can further add surfactant and other auxiliary agent of required preparation needs by effective ingredient and solid or liquid inert substance are mixed and processed.Composite dose of the present invention can be various preparation types, for example: wetting powder, missible oil, suspending agent, aqueous emulsion, microemulsion, granule, dry suspending agent, effervescent tablet and UVL preparation.Make a general survey of the development of the formulations of pesticide, with water-base preparation such as suspending agent, aqueous emulsion, granule etc. low poison with environment amenable formulation serve as preferred.In conjunction with field result of use and preparation cost, promote more favourable with the novel form suspending agent.

The solid carrier that can be used in these preparations comprises following filler: potter's clay class (kaolin, diatomite, bentonite, attapulgite, talcum powder etc.), precipitated calcium carbonate, activated carbon, white carbon, chemical fertilizer (urea, ammonium chloride, ammonium sulfate, ammonium phosphate, ammonium nitrate and composite chemical fertilizer thereof etc.).Liquid-carrier or solvent comprise water, alcohols (methyl alcohol, ethanol etc.), ketone (acetone, cyclohexanone etc.), arene (toluene, dimethylbenzene etc.), non-aromatic hydrocarbon kind solvent (cyclohexane, kerosene, light oil, white oil etc.), ester class (ethyl acetate, butyl acetate etc.), nitrile (acetonitrile, isobutyronitrile etc.), amide-type (N, N-dimethyl formyl gastral cavity, N,N-dimethylacetamide etc.), dimethyl sulfoxide (DMSO) and vegetable oil (soya-bean oil, rapeseed oil, cottonseed wet goods).

Can be used for surfactant of the present invention comprises: alkyl sulfate, alkylsulfonate, alkylaryl sulfonates, alkylnaphthalene sulfonate, alkyl aryl ether, castor oil and their polyoxyethylene product, with condensation product, polyglycol ether, Span and the sugar alcohol derivant of formaldehyde, dodecane sulfonate, dodecyl benzene sulfonate, lignosulfonates.Reach auxiliary agent such as gelatin, carbohydrate (starch, gum Arabic, cellulose derivatives etc.), lignin derivative, bentonite and synthetic polymer (polyvinyl alcohol, polyvinylpyrrolidone, polyacrylic acid etc.), Magnesiumaluminumsilicate, xanthans etc. as dispersant and binding agent effect.

Advantage of the present invention is: the gray mold control efficiency to vegetables, fruit is fabulous, and through experiment confirm, the effect of preventing and treating powdery mildew is also fine, and the agricultural chemicals cost is lower, and effectively delaying drug resistance takes place.

Embodiment

Below in conjunction with embodiment the present invention is done to describe more specifically, but embodiment of the present invention are not limited to these embodiment, the umber described in the embodiment all by weight.

Embodiment 1:

Table 1 different chemical control graw mold of tomato effect and agricultural cost

Handle	Preventive effect %	Agricultural cost (unit/mu)
Handle	Preventive effect %	Agricultural cost (unit/mu)	800 times of 40% Shi Jiale suspending agents	????96.5％	???7.5
But 1000 times of 50% Sukeling wet-millings	????73.7％	???2.5	800 times of 40% Shi Jiale suspending agents	????96.5％	???7.5
But 1000 times of 50% Sukeling wet-millings	????73.7％	???2.5	But 1000 times of 10% Pola peace wet-millings	????59.7％	???6.0
But 800 times of 50% iprodione wet-millings	????68.3％	???6.5	But 1000 times of 10% Pola peace wet-millings	????59.7％	???6.0
But 800 times of 50% iprodione wet-millings	????68.3％	???6.5	But 1000 times of 70% thiophanate methyl wet-millings	????64.0％	???1.2
But 500 times of 50% tmtd wet-millings	????61.1％	???1.1	But 1000 times of 70% thiophanate methyl wet-millings	????64.0％	???1.2
But 500 times of 50% tmtd wet-millings	????61.1％	???1.1	But 1000 times of 50% carbendazim wet-millings	????54.7％	???0.65
1000 times of the own azoles alcohol of 16% procymidone	????97.2％	???1.1	But 1000 times of 50% carbendazim wet-millings	????54.7％	???0.65

Annotate: agricultural cost is in former medicine price

By table 1 as seen, from performance, price comparison, though Sukeling has relative advantage, but, the better effects if that the own azoles alcohol of procymidone is composite dose, simultaneously, the drug effect that the own azoles alcohol of procymidone is composite dose makes up apparently higher than other, and its agricultural chemicals drug effect and cost advantage are stronger.

Embodiment 2:

The different compounded combination of table 2 are to concentration (IC in the inhibition of ash arrhizus bacteria ₅₀) (indoor flat plate test)

Handle	Proportioning	Concentration (IC in the inhibition ₅₀)
Handle	Proportioning	Concentration (IC in the inhibition ₅₀)	Procymidone+triazolone	????3∶1	????2.3010
Procymidone+alkene azoles alcohol	????3∶1	????1.2085	Procymidone+triazolone	????3∶1	????2.3010
Procymidone+alkene azoles alcohol	????3∶1	????1.2085	Procymidone+Tebuconazole	????3∶1	????1.5963
Procymidone+propiconazole	????3∶1	????1.4021	Procymidone+Tebuconazole	????3∶1	????1.5963
Procymidone+propiconazole	????3∶1	????1.4021	Procymidone+Triadimenol	????3∶1	????2.0161
Procymidone+own azoles alcohol	????3∶1	????0.6883	Procymidone+Triadimenol	????3∶1	????2.0161

By table 2 as seen, concentration is minimum in composite dose the inhibition of procymidone and own azoles alcohol.

Embodiment 3:

Table 3 procymidone and own azoles alcohol composite dose and single agent indoor antibacterial test

Treatment combination	The proportioning corruption: oneself	Virulence regression equation	Concentration IC in the inhibition ₅₀	Co-toxicity coefficient CTC
Treatment combination	The proportioning corruption: oneself	Virulence regression equation	Concentration IC in the inhibition ₅₀	Co-toxicity coefficient CTC	Rotten mould+own azoles	3∶1	?Y＝5.3401+1.3858X??R＝0.9589	?0.5683	?752.32
Rotten mould+own azoles	7∶1	?Y＝5.7204+1.6565X??R＝0.9207	?0.3674	?918.07	Rotten mould+own azoles	3∶1	?Y＝5.3401+1.3858X??R＝0.9589	?0.5683	?752.32
Rotten mould+own azoles	7∶1	?Y＝5.7204+1.6565X??R＝0.9207	?0.3674	?918.07	Rotten mould+own azoles	1∶1	?Y＝5.3029+1.5676X??R＝0.9834	?0.6409	?855.71
Own azoles alcohol		?Y＝5.9149+1.1641X??R＝0.9629	?0.1637		Rotten mould+own azoles	1∶1	?Y＝5.3029+1.5676X??R＝0.9834	?0.6409	?855.71
Own azoles alcohol		?Y＝5.9149+1.1641X??R＝0.9629	?0.1637		Procymidone		?Y＝5.2035+1.0647X??R＝0.9701	?0.6439

Shown that by the indoor antibacterial test result shown in the table 3 effect of procymidone and own azoles alcohol compound synergic is very remarkable, (annotate: co-toxicity coefficient surpasses 100 and is synergy), three proportionings were with 7: 1 co-toxicity coefficient maximum.

Embodiment 4

The field disease-preventing effect of table 4 16% procymidone hexaconazole suspending agent under variable concentrations

Handle	Consumption g	Anti-gray mold effect %	Anti-powdery mildew effect %
Handle	Consumption g	Anti-gray mold effect %	Anti-powdery mildew effect %	The own azoles alcohol of procymidone	????30	?78.06±5.68	?73.58±7.94
The own azoles alcohol of procymidone	????40	?89.48±7.11	?82.08±10.23	The own azoles alcohol of procymidone	????30	?78.06±5.68	?73.58±7.94
The own azoles alcohol of procymidone	????40	?89.48±7.11	?82.08±10.23	The own azoles alcohol of procymidone	????50	?97.22±3.49	?91.18±5.78

By in the table 4 as seen, 16% procymidone hexaconazole suspending agent all has the better prevention effect to gray mold and powdery mildew, and with the raising of consumption, drug effect also improves simultaneously.

Embodiment 5:

Take by weighing 2.25 parts of 14.3 parts of procymidone 98% former medicines and own azoles alcohol 90% former medicines, add 5 parts of sodium lignin sulfonates, 600#3 part, 4 parts of anti frozen liquids, 1.2 parts of defoamers, 0.55 part of thickener, 69.7 parts in water was sheared 1 hour, promptly got 16% procymidone hexaconazole suspending agent of the present invention.

Embodiment 6:

Take by weighing 2.25 parts of 14.3 parts of procymidone 98% former medicines and own azoles alcohol 90% former medicines, add 4.5 parts of sodium lignin sulfonates, 1 part of dodecyl sodium sulfate, 77.95 parts of kaolins mix promptly getting the own azoles alcohol of 16% procymidone of the present invention wetting powder behind comminution by gas stream.

Embodiment 7:

Take by weighing 2.25 parts of 14.3 parts of procymidone 98% former medicines and own azoles alcohol 90% former medicines, add 600#2 part, EL-40#3.5 part, 500#1.5 part, 20 parts of dimethylbenzene, DMF10 part, propane diols is heated to 50 ℃ of stirring and dissolving for 8 parts, is ready to 38.45 parts in water, under high shear, solution slowly is added to the water, is cooled to room temperature, promptly get 16% procymidone hexaconazole aqueous emulsion of the present invention.

Claims

1, a kind of built disinfectant, it is characterized in that: its active princlple includes the own azoles alcohol of procymidone and triazole bactericidal agent, and in whole composite dose, the weight percent content of procymidone is 1～50%, and the weight percent content of own azoles alcohol is 0.5～10%.

2, built disinfectant according to claim 1 is characterized in that: the weight percent content of procymidone is 5～20% in described composite dose, and the weight percent content of own azoles alcohol is 0.5～5%.