CN1453025A - Plant leaven with hot and fragrant smell of propylene sulfide and its prepn and use - Google Patents
Plant leaven with hot and fragrant smell of propylene sulfide and its prepn and use Download PDFInfo
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Abstract
The present invention relates to one kind of plant leavening prepared by using plant with hot and fragrant smell of propylene sulfide, yeast and lactobacillus and through fermentation. The present invention also relates to the preparation process of the leavening and its application is treating presbyopia, cataract and other diseases, promoting blood circulation; improving the functions of sexual organs, kidney, cardiac and cerebral vascular system, digestive system, etc.; resisting oxidation, senility and fatigue; lowering blood fat, blood sugar and blood pressure; etc.
Description
(1) technical field:
The present invention relates to a kind of plant fermentation thing, particularly contain the ferment of the hot fragrance plant of allyl sulfides, the invention still further relates to preparation method and its purposes of above-mentioned ferment.
(2) background technology:
Contain the plant of the hot fragrance flavor of allyl sulfides,, both contained abundant nutrition, high medicinal health value is arranged again as Bulbus Allii Cepae, Bulbus Allii, Herba Alii fistulosi, Herba Alii fistulosi, Allium chinense, Folium Allii tuberosi, Herba Apii graveolentis, other kind Herba Alii fistulosi, Bulbus Allii etc.According to record, not only contain diallyl disulfide and sulfur aminoacid in the Bulbus Allii Cepae, peculiar effect with blood fat reducing and arteriosclerosis, also contain protein, cellulose, calcium, phosphorus, ferrum, vitamin A, B, C, P and trace element-selenium, it not only has body-building, the effect of fitness, selenium can also make and produce glutathion in the body, thereby reduction cancer morbidity, play the effect of anti-cancer and cancer-preventing, and contain phytocide in the Bulbus Allii Cepae, to escherichia coli, staphylococcus, streptococcus etc. have stronger inhibition and killing action, strengthen the effect of gastric acid secretion in addition, can reduce or kill noxious bacteria in the stomach, suppress the formation of carcinogen inferior ammonium nitrate, " quercitin " in the Bulbus Allii Cepae be at present known to one of the most effective natural anti-cancer material, have the function that prevents growth of cancer cells.Discover that the people who eats Bulbus Allii Cepae lacks 25% than the probability that the people who does not eat Bulbus Allii Cepae gets a cancer of the stomach more, Bulbus Allii Cepae still is the only vegetable that contains prostaglandin A, and it can stimulate bile secretion, and blood vessel dilating improves little ball that follows, and increases the coronary blood flow quantity.In addition, contain more cysteine in the Bulbus Allii Cepae, this is a kind of defying age material, and therefore deferrable cell ageing, life lengthening, can be used for coronary heart disease, hyperlipidemia, arteriosclerosis, hypertensive Diet Therapy.
Bulbus Allii is go with rice or bread good merchantable brand and the diet flavoring agent that China people always like food, simultaneously also is the traditional simply good medicine that is used for parasite killing, detoxifcation, detumescence, blood stasis dispelling among the people.Modern medicine the analysis showed that, contains protein, fat, carbohydrate, crude fibre, calcium, phosphorus, selenium, germanium, thiamine, riboflavin, nicotinic acid, ascorbic acid of needed by human body etc. in the fresh garlic, and the content of germanium is botanic first place.Also contain the volatile oil that accounts for Bulbus Allii weight 0.2%, contain garlicin (allicin) and multiple pi-allyl in this oil, the sulfide compound of propyl group and methyl, wherein contain 34.1% the diallyl disulphide (being called allicin again) of having an appointment, it is a liposoluble constituent, also contain 43.7% the diallyl trithioether (claiming garlicin again) of having an appointment, be water soluble ingredient.Because the contained this Oleum Bulbus Allii of Bulbus Allii, make it have multiple pharmacological effect, for example: sterilization, antiinflammatory, anticancer, antiviral, enhancing immunity; Blood fat reducing, blood pressure lowering, anti-tampon prevent coronary heart disease, prevent cerebral hemorrhage, help decomposition glucose, supplementing the brain, and blood sugar lowering increases insulin, anti-diabetic; Kill the effect of tumor and cancerous cell, so can prevent and treat nearly hundred kinds of diseases.Particularly to old age four, big disease--cardiovascular diseases, apoplexy, diabetes and cancer had better therapeutic, help life lengthening.Therefore,, appetite be can regulate on the one hand, appetite and digestion promoted as long as often eat an amount of Bulbus Allii (3～10 gram) on ordinary days; Oleum Bulbus Allii can produce ill curing the disease, anosis function of health care being gone into by intestinal absorption after blood also forwards each organ of human body again on the other hand.The present method of this diet-therapy health-preserving that kills two birds with one stone, the praises of many mouthfuls of unanimities both at home and abroad, the fashionable whole world of Bulbus Allii food therapy.
Herba Alii fistulosi nutritious, it can excite sexual desires, and is regarded as the incarnation of love and libido by people always.Modern medicine study shows, enzyme in the Herba Alii fistulosi and various vitamin can guarantee the normal of hormone secretion such as human body, the tonifying YANG nourishing YIN are arranged, the effect of control sexual disorder.
Equally, the plant that contains the hot fragrance flavor of allyl sulfides such as Folium Allii tuberosi, Allium chinense, Herba Apii graveolentis, other kind Herba Alii fistulosi, Bulbus Allii all has high nutritive value and medical value.But contain the plant edible food mode of the hot fragrance flavor of allyl sulfides for these, generally be as vegetable, cooking back is edible, but in gastronomical process, active substance in these plants is subjected to destroying significantly owing to meeting heat, effect can reduce greatly, for this reason, also has the people directly to eat something rare, but the part active ingredient in the above-mentioned plant is water-fast, as diallyl disulphide, therefore, be difficult to when edible be absorbed by the body, and because also there are characteristics such as fresh-keeping difficulty in bright product, people wish these plants are made easy preservation, and are easily edible, easily the goods that absorb.General now employing deodorization method, freezing method, steam distillation, supercritical carbon dioxide extraction method are produced as deodorised garlic, garlic freeze-dried powder, Bulbus Allii quintessence oil etc., though but deodorization method is effectively removed the Bulbus Allii stink, but big alliaceous odor is an allyl disulfide, it is the Main Ingredients and Appearance of Bulbus Allii quintessence oil, when dispeling big alliaceous odor, Bulbus Allii quintessence oil with certain health care functions incurs loss, though lyophilized powder has been saved the active ingredient of bright product from damage, not overcoming wherein partly, active substance is difficult to absorbed defective; And steam distillation and carbon dioxide extraction method all are mainly to extract Bulbus Allii quintessence oil, but can't extract other active ingredient.
Utilize strain such as yeast to above-mentioned thing fermentation, not only can keep the effective ingredient in the plant fully, also can make easier the digesting and assimilating of effective ingredient wherein.But all has high sterilizing ability owing to contain the plant of the hot fragrance flavor of allyl sulfides, therefore be difficult to it is effectively fermented, prior art mainly is to adopt endogenous enzyme that new explanation Bulbus Allii Cepae and/or Bulbus Allii are processed, thereby exploitation sauce, as application number is 00814696.9, name is called the Chinese patent of " Bulbus Allii Cepae and Bulbus Allii biological hydrolysis produce and as the application of natural flavouring ", a kind of flavoring agent base material based on Bulbus Allii Cepae and the generation of Bulbus Allii biological hydrolysis is disclosed, this flavoring agent base material is to carry out controlled hydrolysis by Bulbus Allii Cepae or Bulbus Allii or the mixture of the two under the condition of adding technology enzyme to produce, and its purpose is in order to obtain a kind of flavouring agent of unique flavor.
(3) summary of the invention:
The present invention will disclose a kind of fermented product that contains the hot fragrance flavor of allyl sulfides plant, the ferment that promptly contains the hot fragrance flavor of allyl sulfides plant, it has not only kept original nutrient contents in the plant, easily digest and assimilate, and generated new nutritional labeling, make it to have beyond thought medical health effect.
The present invention also will disclose above-mentioned preparation method and its purposes that contains the ferment of the hot fragrance flavor of allyl sulfides plant.
The present invention mainly is to serve as the fermentation base material with the plant that contains the hot fragrance flavor of allyl sulfides, it is warmed to a selected temperature after, add yeast and ferment, thereby obtain containing the ferment of the hot fragrance flavor of allyl sulfides plant by it.In order to regulate the pH value (what are transferred to) of fermentation base material, keep the fermentation base material to be in best yeastiness, increase the nutrition and the treatment and health function of ferment, and play the effect of synergic fermentation, in the fermentation base material, adding the zymic while, also can add lactobacillus.Its concrete preparation method mainly may further comprise the steps: the fermentation base material A that a) will contain the hot fragrance flavor of allyl sulfides plant is heated to 15 degree～35 degree; B) add yeast or adding yeast and lactobacillus among the A after heating and get B; C) with the B heat-preservation fermentation, generally fermented 7～32 days, get fermentation liquid C.In step a), the temperature of heating of fermentation base material A is preferably 20 degree～25 degree.In the present invention, yeast generally adopts saccharomyces bayanus, TQ sanguinariness yeast or saccharomyces cerevisiae, as 1450 yeast, AM-1 yeast, Lastelli838 yeast, French SAF-OENOS yeast, Canadian LALVINR2 yeast; Lactobacillus can adopt homofermentation Pseudomonas, heterofermentation Pseudomonas, Leuconostoc, Pediococcus, Streptococcus lactobacillus.
The base material A of wherein fermenting can be made by a kind of plant that contains the hot fragrance flavor of allyl sulfides, also can be mixed and made into by more than one plants that contains the hot fragrance flavor of allyl sulfides, and the fermentation base material A can be the plant thickener of smashing, but preferably presses good plant juice.In order to increase the nutrient of fermented yeast bacterium, and make fermentation steadily, make the fermentation of fermentation base material A more thorough, also can include fruit and/or sugar in the fermentation base material A, adding fruit or fruit juice can also increase vitamin and other natural nutrients of this ferment in the fermentation base material, as adding Sucus Vitis viniferae and macaque juice, can increase natural resveratrol and phylloxanthin etc., thereby strengthen this ferment treatment cardiovascular diseases's function, particularly strengthened its treatment presbyopia and bathomorphic function; Add longan juice and then can strengthen the effect that this ferment strengthens renal function; The fermentation base material A also can add peach juice, Lychee juice, Sirikaya etc. other not with the contrary fruit of effect of the present invention.To the sugar that the fermentation base material A adds, can be sucrose, fructose, glucose, vegetable polysaccharides or any sugar or succedaneum with similar effect.
The present invention also can add plant perfume and/or medical material in fermentation liquid C, can carry out after fermentation behind adding plant perfume and/or the medical material, and about 7～15 days of after fermentation treats that generally total sugar content gets final product greater than 0.5% in the fermentation liquid.Adding plant perfume and/or medical material in fermentation liquid C is in order to strengthen this ferment curative effect in a certain respect and to improve abnormal smells from the patient, mouthfeel.Can strengthen its sober-up function as in fermentation liquid C, adding Flos puerariae lobatae, add Folium Ginkgo and can strengthen its treatment cardiovascular diseases's effect, the adding Fructus Momordicae can strengthen it and treat bronchitic effect, add Herba Leonuri and can strengthen its beauty treatment and regulating menstruation effect, add the Radix Angelicae Dahuricae and can strengthen its spot-eliminating beauty treatment effect, the adding Radix Arnebiae (Radix Lithospermi) can strengthen it and treat frosted effect.Certainly also can add Flos Osmanthi Fragrantis, Flos Sophorae, Cyclocarya paliurus Iljinskaja, Flos Rosae Rugosae, golden yellow bluish dogbane, Fructus Citri Limoniae, big Fructus Foeniculi, Flos Chrysanthemi, conyza blinii, Radix Clematidis, Fructus Amomi Rotundus, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Flos Caryophylli, Herba Coriandri, Herba Pogostemonis, Bai Maosuo, Ramulus Et Folium Picrasmae, Radix Gentianae, Fructus psidii guajavae immaturus, Radix Curcumae, Aloe, Herba Menthae Rotundifoliae, Myrrha, Rhizoma Hedychii Spicati, Rhizoma Zingiberis, An Zixiang, Fructus Perillae, go plants such as Rhizoma et radix valerianae, Herba Lysimachiae foenum-graeci, Dianthus chinensis, money flower, Flos lupuli, Lignum Santali Albi or Herba thymi vulgaris to strengthen or to increase its effect in other respects, as long as these plant effects are not opposing with the object of the invention.
The weight ratio of above-mentioned each composition is generally the plant juice that contained the hot fragrance flavor of allyl sulfides in per 1000 minutes, joins the 1mg-10g yeast; The 0-10g lactobacillus, but be preferably the 1mg-10g lactobacillus; 0-400g fruit juice is preferably 10g-400g fruit juice; 0-400g sugar is preferably 10g-400g sugar; 0-30g plant perfume and/or medical material are preferably 1g-30g plant perfume and/or medical material.
The inventor finds that the plant fermentation element that originally contains the hot fragrance flavor of allyl sulfides has the treatment presbyopia, cataract, myopia, the many tears of blurred vision, glaucoma, constipation, gastroenteritis, soreness of waist and knee joint; Promote the systemic blood circulation; Dealcoholic sobering-up, sexual function improving improves renal function, improves cardio and vascular function, improves digestive function, improves climacteric syndrome, improves sleep function; Relieving convulsion, calm the nerves analgesia, heart tonifying function, prophylaxis of cancer, prevention senile dementia; Excite liver function, fibrosis; Antioxidation, defying age, resisting fatigue, anticoagulation, anti-leucocytes reduction, anti-inflammatory; Beauty treatment, fat-reducing is removed speckle, the element that discolors, wrinkle removing stricture of vagina; Increase immunologic function, improve one's memory; Blood fat reducing, blood sugar lowering, blood pressure lowering is adjusted blood viscosity, adjusts metabolism, endocrine regulation; Diuresis, control volume inner cholesterol level, activation blood vessel, expansion artery; The treatment pharyngolaryngitis, bronchitis; The teeth consolidating healthy tooth is treated frosted effect etc.
(4) description of drawings:
Figure 1 shows that the finger printing that ferment clear liquor high performance liquid chromatograph is surveyed among the embodiment 1;
Figure 2 shows that the finger printing that ferment clear liquor high performance liquid chromatograph is surveyed among the embodiment 2;
Figure 3 shows that the finger printing that ferment clear liquor high performance liquid chromatograph is surveyed among the embodiment 3;
Figure 4 shows that the finger printing that ferment clear liquor high performance liquid chromatograph is surveyed among the embodiment 4;
Figure 5 shows that the finger printing that ferment clear liquor high performance liquid chromatograph is surveyed among the embodiment 5.
(5) specific embodiment:
Be several indefiniteness embodiment of the present invention below.
Embodiment 1:
A) the learnt from else's experience Bulbus Allii Cepae 1000g of screening, b) b) to put into service sink (abluent etc.) clean with aseptic water washing; With the Bulbus Allii Cepae broken juice of cleaning, heat to 15 degree; C) add the female SAF-OENOS yeast of 1mg method, fermented 30 days.
Above-mentioned ferment is applied to clinical treatment, observes, test group is taken above-mentioned ferment every day 2 times, and each 80ml (being equivalent to 300 gram Bulbus Allii Cepaes) took 28 days continuously, and the result is as follows:
Annotate: it be produce effects that presbyopia's vision improves 0.1 degree above, and what other symptom had clear improvement is produce effects, and blood glucose value C/mmol decline more than 2 is the influence of produce effects to the experimental hyperlipidemia of Carnis Coturnicis japonicae
| Disease name | Test number (people) | Recovery from illness | Produce effects | Invalid | Obvious effective rate (%) |
| The presbyopia | ????33 | ????29 | ????4 | ????87.8 | |
| Glaucoma | ????15 | ????4 | ????9 | ????2 | ????86.6 |
| The many tears of blurred vision | ????17 | ????6 | ????11 | ????100 | |
| Constipation | ????10 | ????10 | ????100 | ||
| Gastroenteritis | ????20 | ????16 | ????3 | ????1 | ????95 |
| Hypertension | ????30 | ????27 | ????3 | ????90 | |
| Diabetes | ????10 | ????10 | ????100 | ||
| Hypercholesterolemia | ????10 | ????10 | ????100 | ||
| Pharyngolaryngitis | ????10 | ????3 | ????5 | ????2 | ????80 |
| Bronchitis | ????10 | ????1 | ????8 | ????1 | ????90 |
| Cold injury | ????5 | ????3 | ????2 | ????100 |
Select 50 of commercially available Carnis Coturnicis japonicaes for use, be divided into 5 groups at random, 10 every group, the habitual raising begins experiment after 2 days.The normal control group gives common chicken feed, moulding group and each administration group give moulding feedstuff (88.9% common chicken feed, 1% cholesterol, 0.1% methylthiouracil, 10% Adeps Sus domestica), sub-cage rearing (1 Carnis Coturnicis japonicae of whenever raising in cages), ad lib, every Carnis Coturnicis japonicae feeding every day amount is 5g, presses the 0.1ml/10g gastric infusion, every day 1 time; Successive administration is got blood in the carotid artery incision after 1 week, surveys serum triglycerides and serum total cholesterol content, the results are shown in Table.
Effect for reducing fat mg% to the hyperlipidemia Carnis Coturnicis japonicae
| Grouping | Dose mg, ml/kg | Serum triglycerides | Serum total cholesterol |
| Matched group | ??138.43±74.64 | ??188.23±60.66 | |
| The moulding group | ??508.42±158.19 | ??1109.35±465.45 | |
| 1 group | ????5ml | ??200.89±97.73(2) | ??542.89±93.37(2) |
| 2 groups | ????1.0ml | ??180.87±55.10(2) | ??385.95±123.38(2) |
| The clofibrate group | ????70ml | ??265.79±251.18(1) | ??547.15±237.84(2) |
Annotate: n=10
Embodiment 2:
A) the learnt from else's experience Bulbus Allii Cepae 1000g of screening, it is clean with aseptic water washing b) to put into service sink (abluent etc.); With the Bulbus Allii Cepae broken juice of cleaning; C) add the 100g Sucus Vitis viniferae, d) 100g sucrose e) is deployed into mixed liquor, f) above-mentioned mixed liquor is heated to 20 degree; G) add the female SAF-OENOS yeast of 1g method, h) fermentation of 1mg leukonid is 30 days.I) with above-mentioned fermentation liquid clarification, fine straining, sterilization, adjustment concentration content, bottling.
Above-mentioned ferment is applied to clinical treatment, observes, test group is taken above-mentioned ferment every day 2 times, and each 80ml (being equivalent to 300 gram Bulbus Allii Cepaes) took 28 days continuously, and the result is as follows:
| Disease name | Test number (people) | Recovery from illness | Produce effects | Invalid | Obvious effective rate (%) |
| The presbyopia | ????20 | ????5 | ????13 | ??2 | ????90 |
| Diabetes | ????10 | ????10 | ????100 |
Annotate: it is produce effects that presbyopia's vision improves 0.1 degree above, and blood glucose value C/mmol decline more than 2 is produce effects.
Influence to alloxan diabetes mouse blood sugar level:
Get 80 male mices, mice fasting 12h, except that the normal control group, all the other mices are pressed 80mg/kg dosage tail vein injection with the alloxan aqueous solution.From the mouse orbit venous blood collection, use the enzymatic assays blood glucose value behind the 72h.With the mice of blood glucose value more than 16.0mmol/L behind the above-mentioned injection alloxan, be divided into model group, metformin (0.1g/kg) group, Bulbus Allii Cepae element (0.25ml/kg) group at random.The continuous ig. administration of mice 7d, 1 time/d.1h after the last administration, the measuring blood sugar of blood extracting value the results are shown in following table; Compare with model group, plain group of Bulbus Allii Cepae and metformin group all can obviously reduce the blood sugar level of alloxan diabetes mice, have hypoglycemic activity preferably.This combination of table 4 to the influence of alloxan diabetes mouse blood sugar (± s)
| Group | Every kg body weight dosage m/mg | Number of animals | Blood glucose value C/mmol. | |
| Before the L-1 administration | After the administration | |||
| Matched | 20 | 4.93 ± 0.69 | 4.46 ± 0.71 | |
| | 20 | 16.86 ± 9.72 | 14.67 ± 9.56 Δ | |
| Metformin | 100mg | |||
| 20 | 16.61 ± 13.23 | 7.90 ± 3.41 * | ||
| The plain group of Bulbus Allii Cepae | | 20 | 17.35 ± 11.24 | 8.27 ± 4.26 * |
Compare Δ Δ P＜0.01 with matched group, compare with model group
*P＜0.05,
*P＜0.001
Embodiment 3:
A) the learnt from else's experience Bulbus Allii 1000g of screening, it is clean with aseptic water washing b) to put into service sink (abluent etc.); With the Bulbus Allii broken juice of cleaning; C) add the 200g Fructus actinidiae chinensis juice, d) 400g sucrose e) is deployed into mixed liquor, f) above-mentioned mixed liquor is heated to 25 degree; G) add 10mg Canada LALVINR2 yeast, h) fermentation of 100mg heterofermenter is 20 days, i) filters; J) add Folium Ginkgo 10g, k) after fermentation is 10 days.J) with above-mentioned fermentation liquid clarification, fine straining, sterilization, concentrated, dry, k) can be made into oral liquid, soft capsule and microcapsule.
Above-mentioned ferment is applied to clinical treatment, observes, test group is taken above-mentioned ferment every day 2 times, and each 80ml (being equivalent to 300 gram Bulbus Allii Cepaes) took 28 days continuously, and the result is as follows:
| Disease name | Test number (people) | Recovery from illness | Produce effects | Invalid | Obvious effective rate (%) |
| The presbyopia | ????50 | ????8 | ???37 | ????5 | ????90 |
| Myopia is followed | ????80 | ????31 | ???46 | ????3 | ????96.2 |
Annotate: it is produce effects that presbyopia's vision improves more than 0.1 degree, and it is produce effects that near vision improves more than 0.3 degree
Embodiment 4:
A) the learnt from else's experience Bulbus Allii Cepae 500g of screening, Allium chinense 500g, it is clean with aseptic water washing b) to put into service sink (abluent etc.); With Bulbus Allii Cepae, the Allium chinense broken juice of cleaning; C) add 200g macaque juice, d) 200g glucose e) is deployed into mixed liquor, f) above-mentioned mixed liquor is heated to 25 degree; G) add 500mg France SAF-OENOS yeast, h) fermentation of 10g Streptococcus lactobacillus fermentation bacterium is 20 days, i) filters; J) add the 20g Cyclocarya paliurus Iljinskaja, k) after fermentation is 15 days; L), m) can be made into oral liquid, soft capsule and microcapsule with above-mentioned fermentation liquid clarification, fine straining, sterilization, drying.
Above-mentioned ferment is applied to clinical treatment, observes, test group is taken above-mentioned ferment every day 2 times, and each 80ml (being equivalent to 300 gram Bulbus Allii Cepaes) took 28 days continuously, and the result is as follows:
| Disease name | Test number (people) | Recovery from illness | Produce effects | Invalid | Obvious effective rate (%) |
| The presbyopia | ????30 | ????7 | ??21 | ????2 | ????93.3 |
| Diabetes | ????25 | ??25 | ????100 | ||
| Myopia | ????100 | ????41 | ??52 | ????7 | ????93 |
| Improve sleep function | ????30 | ??21 | ????9 | ????70 | |
| Sexual function improving | ????10 | ??6 | ????4 | ????60 | |
| Blood fat reducing | ????10 | ??10 | ????100 |
Annotate: it is produce effects that presbyopia's vision improves more than 0.1 degree, it is produce effects that the myopia vision improves more than 0.3 degree, blood fat: it 50% or more be produce effects that triglyceride, cholesterol, beta lipoprotein reduce, and blood glucose value C/mmol decline more than 2 is produce effects, and what other symptom had clear improvement is produce effects.
Embodiment 5:
A) the learnt from else's experience Herba Alii fistulosi 1000g of screening, it is clean with aseptic water washing b) to put into service sink (abluent etc.); With the Herba Alii fistulosi broken juice of cleaning; C) add 200g longan juice, 100g Fructus Litchi, 100g Sirikaya d) 150g fructose, e) be deployed into mixed liquor, f) above-mentioned mixed liquor is heated to 35 degree; G) add 10g Lastelli838 yeast, h) fermentation of 500Mg Leuconostoc zymocyte is 7 days, i) filters; J) add 30g money flower, k) after fermentation is 15 days; L), m) can be made into oral liquid, soft capsule and microcapsule with above-mentioned fermentation liquid clarification, fine straining, sterilization, drying.
Above-mentioned ferment is applied to clinical treatment, observes, test group is taken above-mentioned ferment every day 2 times, and each 80ml (being equivalent to 300 gram Bulbus Allii Cepaes) took 28 days continuously, and the result is as follows:
| Disease name | Test number (people) | Recovery from illness | Produce effects | Invalid | Obvious effective rate (%) |
| The presbyopia | ????15 | ????14 | ????1 | ????93.3 | |
| Sexual function improving | ????20 | ????16 | ????4 | ????80 | |
| Improve renal function | ????20 | ????19 | ????1 | ????95 | |
| Improve climacteric syndrome | ????30 | ????28 | ????2 | ????93.3 | |
| Resisting fatigue | ????10 | ????8 | ????2 | ????80 | |
| Speckle dispelling | ????12 | ????9 | ????3 | ????75 | |
| Fat-reducing | ????15 | ????13 | ????2 | ????86.6 |
Annotate: presbyopia's produce effects: vision improves more than 0.1 degree; Fat-reducing produce effects: enclose on an empty stomach and reduce more than the 3CM; What other symptom had clear improvement is produce effects.
Show that by the series of experimental research to people and mice this fermentation have the treatment presbyopia, myopia promotes the systemic blood circulation; Raise immunity; Endocrine regulation is adjusted metabolism; Improve one's memory; Sexual function improving improves renal function, blood sugar lowering, blood pressure lowering, resisting fatigue, defying age, anti-leucocytes reduction, the function of anti-inflammatory.Find that simultaneously this fermentation have tangible speckle dispelling, wrinkle removing skin, the plain effect of discoloring, and this ferment also has antiobesity action preferably.
Claims (19)
1, contain the preparation method of the plant fermentation element of the hot fragrance flavor of allyl sulfides, may further comprise the steps:
A) the fermentation base material A that will contain the hot fragrance flavor of allyl sulfides plant is heated to 15 degree～35 degree;
B) add yeast or adding yeast and lactobacillus among the A after heating;
C) the B heat-preservation fermentation is got fermentation liquid thing C.
2, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 1, it is characterized in that: the described plant fermentation base material A that contains the hot fragrance flavor of allyl sulfides, make by one or more plants that contain the hot fragrance flavor of allyl sulfides, or contain the plant of the hot fragrance flavor of allyl sulfides and fruit and/or sugared common modulation by one or more and form.
3, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 1, it is characterized in that: described fruit is Fructus Vitis viniferae, Fructus actinidiae chinensis, honey peach, Arillus Longan, Fructus Litchi, Sirikaya, or the mixture of their arbitrary proportions.
4, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 2, it is characterized in that: described fruit is Fructus Vitis viniferae, Fructus actinidiae chinensis, honey peach, Arillus Longan, Fructus Litchi, Sirikaya, or the mixture of their arbitrary proportions.
5, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 1 is characterized in that: in fermentation liquid C, add plant perfume and/or medical material, or the mixture of their arbitrary proportions, carry out after fermentation.
6, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 2 is characterized in that: in fermentation liquid C, add plant perfume and/or medical material, or the mixture of their arbitrary proportions, carry out after fermentation.
7, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 3 is characterized in that: in fermentation liquid C, add plant perfume and/or medical material, or the mixture of their arbitrary proportions, carry out after fermentation.
8, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 4 is characterized in that: in fermentation liquid C, add plant perfume and/or medical material, or the mixture of their arbitrary proportions, carry out after fermentation.
9, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 5, it is characterized in that: described plant perfume and/or medical material are Flos Osmanthi Fragrantis, Flos puerariae lobatae, Flos Sophorae, Folium Ginkgo, Fructus Momordicae, Cyclocarya paliurus Iljinskaja, Flos Rosae Rugosae, golden yellow bluish dogbane, Fructus Citri Limoniae, Herba Leonuri, big Fructus Foeniculi, Flos Chrysanthemi, conyza blinii, Radix Clematidis, Fructus Amomi Rotundus, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Flos Caryophylli, Herba Coriandri, Herba Pogostemonis, the Radix Angelicae Dahuricae, Bai Maosuo, Ramulus Et Folium Picrasmae, Radix Gentianae, Fructus psidii guajavae immaturus, Radix Arnebiae (Radix Lithospermi), Radix Curcumae, Aloe, Herba Menthae Rotundifoliae, Myrrha, Rhizoma Hedychii Spicati, Rhizoma Zingiberis, An Zixiang, Fructus Perillae, go Rhizoma et radix valerianae, Herba Lysimachiae foenum-graeci, Dianthus chinensis, the money flower, Flos lupuli, Lignum Santali Albi or Herba thymi vulgaris, or the mixture of their arbitrary proportions.
10, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 6, it is characterized in that: described plant perfume and/or medical material are Flos Osmanthi Fragrantis, Flos puerariae lobatae, Flos Sophorae, Folium Ginkgo, Fructus Momordicae, Cyclocarya paliurus Iljinskaja, Flos Rosae Rugosae, golden yellow bluish dogbane, Fructus Citri Limoniae, Herba Leonuri, big Fructus Foeniculi, Flos Chrysanthemi, conyza blinii, Radix Clematidis, Fructus Amomi Rotundus, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Flos Caryophylli, Herba Coriandri, Herba Pogostemonis, the Radix Angelicae Dahuricae, Bai Maosuo, Ramulus Et Folium Picrasmae, Radix Gentianae, Fructus psidii guajavae immaturus, Radix Arnebiae (Radix Lithospermi), Radix Curcumae, Aloe, Herba Menthae Rotundifoliae, Myrrha, last Rhizoma Alpiniae Officinarum, Rhizoma Zingiberis, An Zixiang, Fructus Perillae, go Rhizoma et radix valerianae, Herba Lysimachiae foenum-graeci, Dianthus chinensis, the money flower, Flos lupuli, Lignum Santali Albi or Herba thymi vulgaris, or the mixture of their arbitrary proportions.
11, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 7, it is characterized in that: described plant perfume and/or medical material are Flos Osmanthi Fragrantis, Flos puerariae lobatae, Flos Sophorae, Folium Ginkgo, Fructus Momordicae, Cyclocarya paliurus Iljinskaja, Flos Rosae Rugosae, golden yellow bluish dogbane, Fructus Citri Limoniae, Herba Leonuri, big Fructus Foeniculi, Flos Chrysanthemi, conyza blinii, Radix Clematidis, Fructus Amomi Rotundus, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Flos Caryophylli, coriander, Herba Pogostemonis, the Radix Angelicae Dahuricae, Bai Maosuo, Ramulus Et Folium Picrasmae, Radix Gentianae, Fructus psidii guajavae immaturus, Radix Arnebiae (Radix Lithospermi), Radix Curcumae, Aloe, Herba Menthae Rotundifoliae, Myrrha, last Rhizoma Alpiniae Officinarum, Rhizoma Zingiberis, An Zixiang, Fructus Perillae, go Rhizoma et radix valerianae, Herba Lysimachiae foenum-graeci, Dianthus chinensis, the money flower, Flos lupuli, Lignum Santali Albi or Herba thymi vulgaris, or the mixture of their arbitrary proportions.
12, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 8, it is characterized in that: described plant perfume and/or medical material are Flos Osmanthi Fragrantis, Flos puerariae lobatae, Flos Sophorae, Folium Ginkgo, Fructus Momordicae, Cyclocarya paliurus Iljinskaja, Flos Rosae Rugosae, golden yellow bluish dogbane, Fructus Citri Limoniae, Herba Leonuri, big Fructus Foeniculi, Flos Chrysanthemi, conyza blinii, Radix Clematidis, Fructus Amomi Rotundus, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Flos Caryophylli, coriander, Herba Pogostemonis, the Radix Angelicae Dahuricae, Bai Maosuo, Ramulus Et Folium Picrasmae, Radix Gentianae, Fructus psidii guajavae immaturus, Radix Arnebiae (Radix Lithospermi), Radix Curcumae, Aloe, Herba Menthae Rotundifoliae, Myrrha, Rhizoma Hedychii Spicati, Rhizoma Zingiberis, An Zixiang, Fructus Perillae, go Rhizoma et radix valerianae, Herba Lysimachiae foenum-graeci, Dianthus chinensis, the money flower, Flos lupuli, Lignum Santali Albi or Herba thymi vulgaris, or the mixture of their arbitrary proportions.
13, according to any one described preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides in the claim 1～12, it is characterized in that: in step a), base material A is heated to 20～25 degree.
14, according to any one described preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides in the claim 1～12, it is characterized in that: described yeast is saccharomyces bayanus, TQ sanguinariness yeast or saccharomyces cerevisiae, and described lactobacillus is homofermentation Pseudomonas, heterofermentation Pseudomonas, Leuconostoc, Pediococcus, Streptococcus lactobacillus.
15, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 13, it is characterized in that: described yeast is saccharomyces bayanus, TQ sanguinariness yeast or saccharomyces cerevisiae, described lactobacillus is homofermentation Pseudomonas, heterofermentation Pseudomonas, Leuconostoc, Pediococcus, Streptococcus lactobacillus, or the mixture of their arbitrary proportions.
16, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 14 is characterized in that: described yeast is 1450 yeast, AM-1 yeast, Lastelli838 yeast, the female SAF-OENOS yeast of method, Canadian LALVINR2 yeast.
17, the preparation method that contains the plant fermentation element of the hot fragrance flavor of allyl sulfides according to claim 15 is characterized in that: described yeast is 1450 yeast, AM-1 yeast, Lastelli838 yeast, the female SAF-OENOS yeast of method, Canadian LALVINR2 yeast.
18, any one described plant fermentation element that contains the hot fragrance flavor of allyl sulfides in the claim 1～17.
19, the described purposes of plant fermentation element in the following medicine of preparation that contains the hot fragrance flavor of allyl sulfides of claim 18: treatment presbyopia, cataract, myopia, the many tears of blurred vision, glaucoma, constipation, gastroenteritis, soreness of waist and knee joint; Promote the systemic blood circulation; Dealcoholic sobering-up, sexual function improving improves renal function, improves cardio and vascular function, improves digestive function, improves climacteric syndrome, improves sleep function; Relieving convulsion, calm the nerves analgesia, heart tonifying function, prophylaxis of cancer, prevention senile dementia; Excite liver function, fibrosis; Antioxidation, defying age, resisting fatigue, anticoagulation, anti-leucocytes reduction, anti-inflammatory; Beauty treatment, fat-reducing is removed speckle, the element that discolors, wrinkle removing stricture of vagina; Increase immunologic function, improve one's memory; Blood fat reducing, blood sugar lowering, blood pressure lowering is adjusted blood viscosity, adjusts metabolism, endocrine regulation; Diuresis, control volume inner cholesterol level, activation blood vessel, expansion artery; The treatment pharyngolaryngitis, bronchitis; The teeth consolidating healthy tooth, the treatment cold injury.
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