CN1440288A - 作为酶dpp-iv的抑制剂的杂环化合物 - Google Patents
作为酶dpp-iv的抑制剂的杂环化合物 Download PDFInfo
- Publication number
- CN1440288A CN1440288A CN01812097A CN01812097A CN1440288A CN 1440288 A CN1440288 A CN 1440288A CN 01812097 A CN01812097 A CN 01812097A CN 01812097 A CN01812097 A CN 01812097A CN 1440288 A CN1440288 A CN 1440288A
- Authority
- CN
- China
- Prior art keywords
- purine
- diketone
- alkyl
- dihydro
- base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200001040 | 2000-07-04 | ||
DKPA200001040 | 2000-07-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1440288A true CN1440288A (zh) | 2003-09-03 |
Family
ID=8159598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN01812097A Pending CN1440288A (zh) | 2000-07-04 | 2001-07-04 | 作为酶dpp-iv的抑制剂的杂环化合物 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1561752A1 (de) |
KR (1) | KR20030014394A (de) |
CN (1) | CN1440288A (de) |
AT (1) | ATE299024T1 (de) |
BR (1) | BR0112123A (de) |
CA (1) | CA2411864A1 (de) |
CZ (1) | CZ200319A3 (de) |
DE (1) | DE60111849T2 (de) |
ES (1) | ES2244634T3 (de) |
IL (1) | IL153182A0 (de) |
NO (1) | NO20030021L (de) |
RU (1) | RU2003103103A (de) |
ZA (1) | ZA200209714B (de) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101087756B (zh) * | 2004-07-23 | 2011-04-06 | 纽阿达有限责任公司 | 肽酶抑制剂 |
CN102079743A (zh) * | 2004-03-15 | 2011-06-01 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
CN102276627A (zh) * | 2010-04-29 | 2011-12-14 | 山东轩竹医药科技有限公司 | 吡啶并杂环衍生物 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012170702A1 (en) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
CN103509023B (zh) * | 2012-06-20 | 2014-08-27 | 成都苑东药业有限公司 | 黄嘌呤衍生物 |
DK2970303T6 (en) | 2013-03-15 | 2018-10-08 | Hydra Biosciences Inc | SUBSTITUTED XANTHINES AND PROCEDURES FOR USING IT |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2205815A1 (de) * | 1972-02-08 | 1973-08-16 | Hoechst Ag | Piperazinderivate und verfahren zu ihrer herstellung |
GB9020959D0 (en) * | 1990-09-26 | 1990-11-07 | Beecham Group Plc | Novel compounds |
-
2001
- 2001-07-04 EP EP05008243A patent/EP1561752A1/de not_active Withdrawn
- 2001-07-04 CN CN01812097A patent/CN1440288A/zh active Pending
- 2001-07-04 BR BR0112123-5A patent/BR0112123A/pt not_active IP Right Cessation
- 2001-07-04 CA CA002411864A patent/CA2411864A1/en not_active Abandoned
- 2001-07-04 CZ CZ200319A patent/CZ200319A3/cs unknown
- 2001-07-04 IL IL15318201A patent/IL153182A0/xx unknown
- 2001-07-04 RU RU2003103103/04A patent/RU2003103103A/ru not_active Application Discontinuation
- 2001-07-04 DE DE60111849T patent/DE60111849T2/de not_active Expired - Fee Related
- 2001-07-04 AT AT01947211T patent/ATE299024T1/de not_active IP Right Cessation
- 2001-07-04 ES ES01947211T patent/ES2244634T3/es not_active Expired - Lifetime
- 2001-07-04 KR KR1020027017726A patent/KR20030014394A/ko not_active Application Discontinuation
-
2002
- 2002-11-29 ZA ZA200209714A patent/ZA200209714B/xx unknown
-
2003
- 2003-01-03 NO NO20030021A patent/NO20030021L/no unknown
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102079743A (zh) * | 2004-03-15 | 2011-06-01 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
CN102079743B (zh) * | 2004-03-15 | 2020-08-25 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
CN101087756B (zh) * | 2004-07-23 | 2011-04-06 | 纽阿达有限责任公司 | 肽酶抑制剂 |
CN102276627A (zh) * | 2010-04-29 | 2011-12-14 | 山东轩竹医药科技有限公司 | 吡啶并杂环衍生物 |
CN102276627B (zh) * | 2010-04-29 | 2013-07-31 | 山东轩竹医药科技有限公司 | 吡啶并杂环衍生物 |
Also Published As
Publication number | Publication date |
---|---|
ES2244634T3 (es) | 2005-12-16 |
NO20030021L (no) | 2003-03-03 |
IL153182A0 (en) | 2003-06-24 |
ATE299024T1 (de) | 2005-07-15 |
CZ200319A3 (cs) | 2003-05-14 |
ZA200209714B (en) | 2003-08-19 |
RU2003103103A (ru) | 2004-08-20 |
CA2411864A1 (en) | 2002-01-10 |
NO20030021D0 (no) | 2003-01-03 |
DE60111849T2 (de) | 2006-06-08 |
BR0112123A (pt) | 2003-05-06 |
EP1561752A1 (de) | 2005-08-10 |
DE60111849D1 (de) | 2005-08-11 |
KR20030014394A (ko) | 2003-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
AD01 | Patent right deemed abandoned | ||
C20 | Patent right or utility model deemed to be abandoned or is abandoned |