CN1425394A - Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method - Google Patents
Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method Download PDFInfo
- Publication number
- CN1425394A CN1425394A CN 01138267 CN01138267A CN1425394A CN 1425394 A CN1425394 A CN 1425394A CN 01138267 CN01138267 CN 01138267 CN 01138267 A CN01138267 A CN 01138267A CN 1425394 A CN1425394 A CN 1425394A
- Authority
- CN
- China
- Prior art keywords
- radix
- weight portion
- weight portions
- weight
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000006820 Arthralgia Diseases 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title claims description 19
- 230000003213 activating effect Effects 0.000 title claims description 10
- 238000002156 mixing Methods 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 4
- 238000012856 packing Methods 0.000 claims abstract description 4
- 238000002360 preparation method Methods 0.000 claims abstract description 4
- 238000005303 weighing Methods 0.000 claims abstract description 4
- 238000007689 inspection Methods 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
- 210000000582 semen Anatomy 0.000 claims description 22
- 239000003814 drug Substances 0.000 claims description 18
- 239000012567 medical material Substances 0.000 claims description 17
- 235000021419 vinegar Nutrition 0.000 claims description 11
- 239000000052 vinegar Substances 0.000 claims description 11
- 241000628997 Flos Species 0.000 claims description 10
- 210000000481 breast Anatomy 0.000 claims description 10
- 239000004576 sand Substances 0.000 claims description 10
- 239000000796 flavoring agent Substances 0.000 claims description 9
- 235000019634 flavors Nutrition 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- 239000003027 oil sand Substances 0.000 claims description 7
- 239000006187 pill Substances 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims description 7
- 238000012216 screening Methods 0.000 claims description 7
- 241000237636 Pheretima Species 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 5
- 238000007873 sieving Methods 0.000 claims description 4
- 238000003892 spreading Methods 0.000 claims description 4
- 241000717739 Boswellia sacra Species 0.000 claims description 3
- 239000004863 Frankincense Substances 0.000 claims description 3
- 241000238631 Hexapoda Species 0.000 claims description 3
- 241000238370 Sepia Species 0.000 claims description 3
- 241000607479 Yersinia pestis Species 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 239000008367 deionised water Substances 0.000 claims description 3
- 229910021641 deionized water Inorganic materials 0.000 claims description 3
- 239000012153 distilled water Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims description 3
- 238000010791 quenching Methods 0.000 claims description 3
- 238000001238 wet grinding Methods 0.000 claims description 3
- 235000015099 wheat brans Nutrition 0.000 claims description 3
- 241000241550 Cyathula Species 0.000 claims description 2
- 241000245240 Lonicera Species 0.000 claims description 2
- 241001057584 Myrrha Species 0.000 claims description 2
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 claims description 2
- 241001530126 Scrophularia Species 0.000 claims description 2
- 244000107975 Strychnos nux-vomica Species 0.000 claims description 2
- 210000003195 fascia Anatomy 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 3
- 201000003068 rheumatic fever Diseases 0.000 abstract description 3
- 244000077995 Coix lacryma jobi Species 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- RONWGALEIBILOG-VMJVVOMYSA-N quinine sulfate Chemical compound [H+].[H+].[O-]S([O-])(=O)=O.C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21.C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 RONWGALEIBILOG-VMJVVOMYSA-N 0.000 abstract 1
- 208000007442 rickets Diseases 0.000 abstract 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 201000010099 disease Diseases 0.000 description 8
- 238000012360 testing method Methods 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- QXDMQSPYEZFLGF-UHFFFAOYSA-L calcium oxalate Chemical compound [Ca+2].[O-]C(=O)C([O-])=O QXDMQSPYEZFLGF-UHFFFAOYSA-L 0.000 description 4
- 235000013339 cereals Nutrition 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- 208000036487 Arthropathies Diseases 0.000 description 3
- 208000012659 Joint disease Diseases 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 206010039073 rheumatoid arthritis Diseases 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 2
- 208000008765 Sciatica Diseases 0.000 description 2
- 206010067868 Skin mass Diseases 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229960001680 ibuprofen Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 206010002556 Ankylosing Spondylitis Diseases 0.000 description 1
- 206010004053 Bacterial toxaemia Diseases 0.000 description 1
- 206010062746 Carditis Diseases 0.000 description 1
- 206010008748 Chorea Diseases 0.000 description 1
- 241001459693 Dipterocarpus zeylanicus Species 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 206010023232 Joint swelling Diseases 0.000 description 1
- 208000009525 Myocarditis Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000013222 Toxemia Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 235000019636 bitter flavor Nutrition 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 208000012601 choreatic disease Diseases 0.000 description 1
- 235000019504 cigarettes Nutrition 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000004247 hand Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000021646 inflammation of heart layer Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 206010048628 rheumatoid vasculitis Diseases 0.000 description 1
- 210000003497 sciatic nerve Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Images
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The bolus for eliminating arthralgia and dredging the meridian passage is prepared with phellodendron bark, astractylodes rhizome, Coix seed, Sichuan achryanthes root, Chinese flowering quine and other Chinese medicinal materials in certain proportion and through weighing, mixing, crushing, preparing wet bolus, stoving, inspection packing and other steps. It is used in treating rheumatosis, rheumatic fever, titanic rachitis and scatica. It has simple preparation process and high treating effect.
Description
Technical field bolus for eliminating arthralgia and activating energy flow in channels and collaterals and compound method thereof belong to the treatment rheumatism be made up of vegetable material or the preparation technique field of rheumatoid disease medicine.
Background technology shows according to applicant's clinical experience: rheumatism or rheumatoid common sympton are the whole body pain based on arthropathy, especially rheumatoid arthritis, how pathogenic factor is deeply through marrow bone joint, sharp ache, touchingly do not heal, so that the useless usefulness of joint deformity, one of difficult problem that this also is in treatment to be run into.Therefore, need overcome toxic and side effects, the medicine strength of the high violent medicine of the traditional Chinese medical science single, can not take into account and doctor trained in Western medicine only can delay this type of advancing of disease process and can not stop or cure the defective of this type of disease.The applicant attempts to develop a kind of these defectives that can not only overcome, but also have evident in efficacy, easy to use, be easy to carry, cheap treatment rheumatism or rheumatoid bolus for eliminating arthralgia and activating energy flow in channels and collaterals.
Summary of the invention is exempted from the numbness ball of living and is made of the medical material of following component and corresponding weight part ratio:
Cortex Phellodendri 18 weight portion Rhizoma Atractylodis 14 weight portions
Semen Coicis 14 weight portion Radix Cyathulaes 14 weight portions
Fructus Chaenomelis 14 weight portion Flos Carthamis 10 weight portions
Carapax Trionycis (processed with vinegar) 20 weight portion Caulis Spatholobis 14 weight portions
Radix Salviae Miltiorrhizae 14 weight portion Radix Angelicae Sinensis 14 weight portions
Flos Lonicerae 20 weight portion Herba Taraxacis 20 weight portions
The Rhizoma Anemarrhenae 18 weight portion Rhizoma Chuanxiongs 10 weight portions
Cortex Moutan 10 weight portion Radix Paeoniae Rubra 10 weight portions
The Radix Paeoniae Alba 14 weight portion Radix Gentianae Macrophyllae 10 weight portions
The system breast does not have 18 weight portion Pheretimas, 10 weight portions
Radix Stephaniae Tetrandrae 14 weight portion Radix Scrophulariaes 14 weight portions
The Ramulus Cinnamomi 10 weight portion Radix Rehmanniae 18 weight portions
Radix Sophorae Flavescentis 14 weight portion Bi 14 weight portions
Ramulus Mori 18 weight portion Caulis Loniceraes 14 weight portions
Semen Strychni (processed) 50 weight portions.
Bolus for eliminating arthralgia and activating energy flow in channels and collaterals is prepared according to following technological process:
(1) form according to the medical material of setting and weight part ratio is drawn materials, screening the go mouldy medical material of free from insect pests of fresh nothing is raw material;
(2) Semen Strychni (processed), the weight part ratio of getting Semen Strychni and water is 1: 8, places water to soak 10 days Semen Strychni, changes water once, and takes out, removes the peel, cuts into slices, dries in per 2 days; In Semen Strychni and sand is that 1: 2 ratio adds sand, puts into pot after the mixing, places parch on the stove, makes it to be sepia or dark brown, withered shape, and shakeout is pulverized, and through 80 order sieving to obtain fine powder shapes, is Nux vomica (processed), and is standby;
(3) Carapax Trionycis (processed with vinegar): get crude drug and clean, soaked 1～2 day, place in the steamer, steamed 10～15 minutes with boiling water, hot water is put in taking-up, removes the skin and flesh fascia immediately, cleans, dries, gets oil-sand and place in the pot, parch with high heat, make when oil-sand is lubricious easily to be stirred, add clean Carapax Trionycis again, stir-fry when being faint yellow to the surface, shakeout, taking-up, drop into while hot to soak in the general tablet vinegar liquid and quench, pull out, drying promptly is buff;
(4) the system breast does not have, and with high heat frying pan is burnt heat, smolders and is advisable to be sprinkled into Testa Tritici, and the Olibanum Myrrha of mixed in equal amounts is dropped in the pot, constantly stir, fry and to be pitchy or brownish black to the surface, glossy, be degree when feeble QI is fragrant, sieve goes the wheat bran spreading for cooling, and is standby, and breast is not 5: 1 with the ratio of Testa Tritici;
(5) concoct 26 flavor medicines such as Cortex Phellodendri, with reference to the standard of one one of country's " pharmacopeia " (version in 2000), 26 flavor medical materials such as Cortex Phellodendri, Rhizoma Atractylodis, Semen Coicis, Radix Cyathulae, Fructus Chaenomelis, Flos Carthami, Caulis Spatholobi, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Flos Lonicerae, Herba Taraxaci, the Rhizoma Anemarrhenae, Rhizoma Chuanxiong, Cortex Moutan, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Gentianae Macrophyllae, Pheretima, Radix Stephaniae Tetrandrae, Radix Scrophulariae, Ramulus Cinnamomi, the Radix Rehmanniae, Radix Sophorae Flavescentis, Bi , Ramulus Mori, Caulis Lonicerae are concocted respectively;
(6) with 28 flavor medical material mix homogeneously such as Cortex Phellodendri, pulverizing, with 80 order sieving to obtain fine powder shapes;
(7) take by weighing Semen Strychni (processed) and other 28 flavor medical material mix homogeneously with the equivalent incremental method;
(8) wet-pill making: mix well mutually with the medicinal raw material of mixing fine powders shape with purified water or deionized water or distilled water, water is 1: 2 with the medicinal raw material ratio, again it is placed coating pan, presses the wet-milling modulus method of having granulated, it is constantly increased be shaped, make wet ball by 6 of every grams;
(9) oven dry, the wet ball of the screening of learning from else's experience place heated air circulation device or baking oven stand to spare, and constantly stir under 58 ℃ environment, take out after oven dry in 6～8 hours;
(10) quality inspection, by every bottle 120 gram packing, print.
Pharmacological evaluation proves: Semen Strychni activating collaterals and eliminating stagnation, subduing swelling and relieving pain; Cortex Phellodendri, Rhizoma Atractylodis, Semen Coicis, Radix Sophorae Flavescentis, Bi , Radix Cyathulae heat clearing and damp drying; Flos Lonicerae, Radix Scrophulariae, Herba Taraxaci, Radix Salviae Miltiorrhizae, system breast do not have,, clearing away heat-fire, removing toxic substances and promoting subsidence of swelling, removing obstruction for relieving pain; Ramulus Cinnamomi, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Paeoniae Alba, the Radix Rehmanniae, the Rhizoma Anemarrhenae, Flos Carthami, Caulis Spatholobi, Cortex Moutan nourish blood and blood, blood-activating analgetic; Fructus Chaenomelis, Ramulus Mori, Caulis Lonicerae, Radix Gentianae Marcrophyllae, Radix Stephaniae Tetrandrae, the Shujin that dispels the wind, moisturize dehumidifying; Carapax Trionycis (processed with vinegar), Pheretima, yin nourishing eliminating stagnation.
In order to ensure the quality of medicine, the inventor has worked out following implementation criteria:
Character: this product is the yellowish-brown or the tan watered pill; Feeble QI perfume (or spice), mildly bitter flavor.
Microscope is differentiated: get this product powder, put microscopically and observe as seen: starch grain is extremely many, assembles agglomeratingly, and the simple grain class is spherical or avette, and omphalion herringbone shape, starlike or weak point stitch shape.Nonglandular hair is unicellular, most cataclasm lobe, and complete person's base portion expands like the stone cell sample, and wall is extremely thick, pit longitudinal crevasse shape, cell contains the yellowish-brown thing.The fiber foresythia, normal bunchy, peripheral cell contains prism of calcium oxalate, forms crystalline cellulose.Needle-like calcium oxalate crystal is numerous, does not advise filling in parenchyma cell, and needle is tiny, long 8-30um, and it is little shaft-like or square that rare crystallization is.Calcium oxalate sand crystal is more, does not plan shape, and sand crystal is intensive, one jiao in the gathering cell that has.Calcium oxalate cluster crystal is numerous, is dispersed in parenchyma cell, and constant to dozens of vertically is arranged in rows.Nonglandular hair is extremely many, and is unicellular, and straight or crooked slightly, there are fine excipuliform or blister projection in the surface.The pollen grain similar round, buff, 3 germinal aperatures of tool, outer wall has dentation.
Each index of being checked should meet " the regulation of an appendix IA of Chinese pharmacopoeia (version in 2000).
Cure mainly: rheumatoid arthritis, rheumatic fever, ankylosing spondylitis, sciatica.
Usage and consumption: hora somni(hs) adult clothes 6～12 restrain every night, and old man weakling, children's are cut down according to the circumstance or followed the doctor's advice.
The taboo: avoid cold and uncooked food, through, pregnant, avoid clothes term, the period in a medicine men and women can not have sexual intercourse.
Specification: 120 gram/bottles.
Storage: airtight, moistureproof.
In order to verify curative effect of the present invention, the applicant once carried out clinical trial in three batches to 300 routine patients, now its result was summarized as follows:
First test is the treatment rheumatoid arthritis, patient's 160 examples, patient's polyphyly are because of the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, and the four stages in the course of an epidemic febrile disease is lacked of proper care, internal organs negative and positive internal injury, turbid interior the giving birth to of blood stasis expectorant causes that with pathological changes outside chronic, symmetry, the little arthritis of polytropy and the joint be the disease of main clinical manifestation.Decide patient's 160 examples and be the treatment group.Select 160 routine patients else and be matched group, take ibuprofen.The patient shows (comprising rheumatoid subcutaneous nodule, rheumatoid vasculitis, cardiopulmonary infringement, nervous system and other performance) state of an illness weight from arthropathy (comprise deadlock in morning, joint swelling and pain, joint motion are limited, arthralgia become migration and symmetry) and does not wait outside the joint.They comprise early, middle and late three phases respectively, treatment group patient obeys pill 6～12 grams every night and does not wait, decide on state of an illness weight, this test was a course of treatment in fixed 20 days, after the treatment of three courses of treatment, performance all has improvement in various degree outside arthropathy and the joint, and treatment group effective percentage is 95%, and the matched group effective percentage is 62.5%.
The second batch of test is that the treatment sciatica is suffered from 80 examples, and the patient be because of spine disorders, and the position of illness, pelvis illness and the injection of buttocks medicine is improper etc. in the spinal canal causes that one-sided (seeing few bilateral) lower limb move towards to occur pain along sciatic nerve.Decide on state of an illness weight, obey this pill 6-12 gram every night and do not wait, this test was a course of treatment in 7 days, and 80 routine patient treatments are after three courses of treatment, and effective percentage is 97.5%, and cure rate is 87.5%.And the matched group effective percentage is 53%.
The 3rd batch of test is treatment rheumatic fever patient 60 examples, the patient is because of environmental factors (geography, humidity, season etc.), acute or the chronic general ICT property disease of a kind of outbreak repeatedly that multiple factor such as economic situation and age causes, clinical manifestation is based on carditis, can be with heating, toxemia, subcutaneous nodule, chorea etc., conditions of patients comprises that degeneration oozes out phase, propagation phase, three phases of hardening period.Select 60 routine patients else and be matched group, the every clothes pill of treatment group patient 6-10 gram does not wait, and decides on the disease weight, and this test was a course of treatment in fixed 20 days, and after three course of therapy, the employed medicine of the matched group of second and third batch clinical trial still is an ibuprofen.The effective percentage 98.33% of treatment group, and the matched group effective percentage is 90%.
The beneficial effect that facts have proved bolus for eliminating arthralgia and activating energy flow in channels and collaterals is:
(1) have liver and kidney tonifying, expelling wind and removing dampness, clearing away heat and cooling blood, removing toxic substances and promoting subsidence of swelling, the removing obstruction from collaterals pain relieving improves the human body immunity, treating both the principal and secondary aspects of a disease.
(2) preparation method is simple, and medicine is easy to apolegamy.
(3) course of treatment is shorter, evident in efficacy.
(4) be easy to carry, easy to use, mouthfeel is good.
Description of drawings can be drawn out this medicine production process chart according to the compound method of bolus for eliminating arthralgia and activating energy flow in channels and collaterals, and as shown in drawings, existing each link supplementary notes to flow chart are as follows:
(1) draw materials according to the medical material component and the weight portion of defined, screening the go mouldy medical material of free from insect pests of fresh nothing is raw material.
(2) Semen Strychni is concocted, and the weight ratio of Semen Strychni and water is 1: 8, places water to soak 10 days Semen Strychni, changes water once in per two days; In Semen Strychni and sand is that 1: 2 ratio adds sand, mixes parch, fry to sepia or dark brown, and withered shape, shakeout is pulverized, and is screened into powdery through 80 orders.
(3) Carapax Trionycis (processed with vinegar) is cleaned the back and was soaked 1～2 day, and boiling water steamed 10～15 minutes, clean and dry, it is placed the oil-sand pot, oil-sand is advisable can flood medical material, parch with high heat makes its surface be faint yellow, shakeout, take out, and drop into while hot to soak in the tablet vinegar liquid and quench, pull drying out, be buff, breaking brittle failure off with the fingers and thumb with hands is appropriateness.In addition, oil-sand can be produced by the following method: with screening out coarse grain and particulate, thick fluvial sand is cleaned and is gone mud, drying to be placed on a pot internal heating in getting, and add 1%～2% vegetable oil stir to oil to the greatest extent cigarette loose, when the color and luster of sand is evenly deepened, take out spreading for cooling, standby.
(4) the system breast does not have, and with high heat pot is burnt heat, smolders and is advisable to be sprinkled into Testa Tritici, and mixed in equal amounts Olibanum and medicine are dropped in the pot, constantly stir, stir-fry is pitchy or brownish black to the surface, and is glossy, is degree when feeble QI is fragrant, sieve goes the wheat bran spreading for cooling, and is standby, and breast is not 5: 1 with the ratio of Testa Tritici.
(5) process of preparing Chinese medicine of 26 flavor medicines such as Cortex Phellodendri: should concoct respectively with reference to the standard of one one of country's " pharmacopeia " (version in 2000).
(6) wet-pill making is used purified water, or deionized water or distilled water mix well mutually with the medical material mixing fine powders, and the two weight ratio is 1: 2, again it is placed coating pan, presses the wet-milling modulus method of having granulated, and its is constantly increased be shaped, and makes wet ball by 6 of every grams.
(7) oven dry will place heated air circulation device or baking oven stand even through the wet ball of screening, constantly stir under 58 ℃ environment, take out after oven dry in 6～8 hours.
(8) by every bottle 120 gram packing.
The specific embodiment: the applicant thinks that above-mentioned each given medical material component, the weight ratio part and the technological process of production are realization a kind of optimal way of the present invention.
Claims (2)
1. bolus for eliminating arthralgia and activating energy flow in channels and collaterals is characterized in that constituting by the medical material of following component and weight/power ratio part:
Cortex Phellodendri 18 weight portion Rhizoma Atractylodis 14 weight portions
Semen Coicis 14 weight portion Radix Cyathulaes 14 weight portions
Fructus Chaenomelis 14 weight portion Flos Carthamis 10 weight portions
Carapax Trionycis (processed with vinegar) 20 weight portion Caulis Spatholobis 14 weight portions
Radix Salviae Miltiorrhizae 14 weight portion Radix Angelicae Sinensis 14 weight portions
Flos Lonicerae 20 weight portion Herba Taraxacis 20 weight portions
The Rhizoma Anemarrhenae 18 weight portion Rhizoma Chuanxiongs 10 weight portions
Cortex Moutan 10 weight portion Radix Paeoniae Rubra 10 weight portions
The Radix Paeoniae Alba 14 weight portion Radix Gentianae Macrophyllae 10 weight portions
The system breast does not have 18 weight portion Pheretimas, 10 weight portions
Radix Stephaniae Tetrandrae 14 weight portion Radix Scrophulariaes 14 weight portions
The Ramulus Cinnamomi 10 weight portion Radix Rehmanniae 18 weight portions
Radix Sophorae Flavescentis 14 weight portion Bi 14 weight portions
Ramulus Mori 18 weight portion Caulis Loniceraes 14 weight portions
Semen Strychni (processed) 50 weight portions.
2. the preparation method of a bolus for eliminating arthralgia and activating energy flow in channels and collaterals comprises that officinal process of preparing Chinese medicine method and equivalent increase progressively the method for taking by weighing, and is characterized in that being prepared according to following technological process:
(1) form according to the medical material of setting and weight portion is drawn materials, screening the go mouldy medical material of free from insect pests of fresh nothing is raw material;
(2) Semen Strychni (processed), the weight part ratio of getting Semen Strychni and water is 1: 8, places water to soak 10 days Semen Strychni, changes water once, and takes out, removes the peel, cuts into slices, dries in per 2 days; In Semen Strychni and sand is that 1: 2 ratio adds sand, puts into pot after the mixing, places parch on the stove, makes it to be sepia or dark brown, withered shape, and shakeout is pulverized, and through 80 order sieving to obtain fine powder shapes, is Nux vomica (processed), and is standby;
(3) Carapax Trionycis (processed with vinegar): get crude drug and clean, soaked 1～2 day, place again in the steamer, steamed 10～15 minutes with boiling water, hot water is put in taking-up, remove the skin and flesh fascia immediately, clean, dry, get oil-sand and place in the pot, parch with high heat, make oil-sand lubricious, when stirring, add clean Carapax Trionycis again, stir-fry when being faint yellow to the surface, shakeout, taking-up drop into general tablet vinegar while hot; Soak in the vinegar liquid and quench, pull out, drying promptly is buff;
(4) the system breast does not have, and with high heat frying pan is burnt heat, smolders and is advisable to be sprinkled into Testa Tritici, the Olibanum Myrrha of mixed in equal amounts is dropped in the pot, constantly stir, stir-fry is pitchy or brownish black to the surface, glossy, go the wheat bran spreading for cooling for degree sieve when feeble QI is fragrant, standby, breast is not 5: 1 with the ratio of Testa Tritici;
(5) concoct 26 flavor medicines such as Cortex Phellodendri, with reference to the standard of one one of country's " pharmacopeia " (version in 2000), 26 flavor medical materials such as Cortex Phellodendri, Rhizoma Atractylodis, Semen Coicis, Radix Cyathulae, Fructus Chaenomelis, Flos Carthami, Caulis Spatholobi, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Flos Lonicerae, Herba Taraxaci, the Rhizoma Anemarrhenae, Rhizoma Chuanxiong, Cortex Moutan, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Gentianae Macrophyllae, Pheretima, Radix Stephaniae Tetrandrae, Radix Scrophulariae, Ramulus Cinnamomi, the Radix Rehmanniae, Radix Sophorae Flavescentis, Bi , Ramulus Mori, Caulis Lonicerae are concocted respectively;
(6) with 26 flavor medical materials such as Cortex Phellodendri and Carapax Trionycis (processed with vinegar), make breast and do not have mix homogeneously, pulverizing, with 80 order sieving to obtain fine powder shapes;
(7) taking by weighing Semen Strychni (processed) with the equivalent incremental method mixes mutually with other 28 flavor medical material;
(8) wet-pill making: the medicinal raw material with purified water or deionized water or distilled water and mixing fine powders shape is mixed well, water is 1: 2 with the medicinal raw material ratio, again it is placed coating pan, presses the wet-milling modulus method of having granulated, it is constantly increased be shaped, make wet ball by 6 of every grams;
(9) oven dry, the wet ball of the screening of learning from else's experience place heated air circulation device or baking oven stand to spare, and constantly stir under 58 ℃ environment, take out after oven dry in 6～8 hours;
(10) quality inspection, by every bottle 120 gram, packing, print.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011382678A CN100379440C (en) | 2001-12-11 | 2001-12-11 | Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011382678A CN100379440C (en) | 2001-12-11 | 2001-12-11 | Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1425394A true CN1425394A (en) | 2003-06-25 |
| CN100379440C CN100379440C (en) | 2008-04-09 |
Family
ID=4674479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011382678A Expired - Lifetime CN100379440C (en) | 2001-12-11 | 2001-12-11 | Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100379440C (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1318076C (en) * | 2003-11-03 | 2007-05-30 | 阎凤宝 | Quick effective heat-reducing and bone numbness releasing medicine |
| CN101085222B (en) * | 2007-07-20 | 2010-06-02 | 李桂荣 | Plaster for relieving pain |
| CN101249214B (en) * | 2008-04-07 | 2010-08-25 | 康正海 | Xiabing arrowhead spray for curing various pain |
| CN101530598B (en) * | 2009-04-15 | 2011-11-02 | 张磊 | Plaster used for hyperosteogeny |
| CN102600404A (en) * | 2012-03-28 | 2012-07-25 | 裴晶 | Traditional Chinese medicine for treating undifferentiated spondyloarthropathy |
| CN101939018B (en) * | 2008-02-19 | 2013-02-20 | 庆熙大学产学协力团 | Composition comprising mixed herbal extract of lonicera japonica thunb and anemarrhena asphodeloides bunge preventing and treating arthritis |
| CN103690833A (en) * | 2013-12-30 | 2014-04-02 | 张振刚 | Traditional Chinese medicine for treating rheumatoid arthritis |
| CN107890426A (en) * | 2017-11-20 | 2018-04-10 | 安徽佳凯药业股份有限公司 | A kind of frying production method of the prepared slices of Chinese crude drugs |
| CN110101738A (en) * | 2019-06-12 | 2019-08-09 | 张九海 | Bitong capsule for treating numbness and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051468C (en) * | 1997-05-06 | 2000-04-19 | 刁金山 | Capsule for curing rheumatism |
-
2001
- 2001-12-11 CN CNB011382678A patent/CN100379440C/en not_active Expired - Lifetime
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1318076C (en) * | 2003-11-03 | 2007-05-30 | 阎凤宝 | Quick effective heat-reducing and bone numbness releasing medicine |
| CN101085222B (en) * | 2007-07-20 | 2010-06-02 | 李桂荣 | Plaster for relieving pain |
| CN101939018B (en) * | 2008-02-19 | 2013-02-20 | 庆熙大学产学协力团 | Composition comprising mixed herbal extract of lonicera japonica thunb and anemarrhena asphodeloides bunge preventing and treating arthritis |
| CN101249214B (en) * | 2008-04-07 | 2010-08-25 | 康正海 | Xiabing arrowhead spray for curing various pain |
| CN101530598B (en) * | 2009-04-15 | 2011-11-02 | 张磊 | Plaster used for hyperosteogeny |
| CN102600404A (en) * | 2012-03-28 | 2012-07-25 | 裴晶 | Traditional Chinese medicine for treating undifferentiated spondyloarthropathy |
| CN102600404B (en) * | 2012-03-28 | 2013-11-13 | 刘玉柱 | Traditional Chinese medicine for treating undifferentiated spondyloarthropathy |
| CN103690833A (en) * | 2013-12-30 | 2014-04-02 | 张振刚 | Traditional Chinese medicine for treating rheumatoid arthritis |
| CN103690833B (en) * | 2013-12-30 | 2016-01-13 | 孙振刚 | A kind of Chinese medicine for the treatment of rheumatic arthritis |
| CN107890426A (en) * | 2017-11-20 | 2018-04-10 | 安徽佳凯药业股份有限公司 | A kind of frying production method of the prepared slices of Chinese crude drugs |
| CN110101738A (en) * | 2019-06-12 | 2019-08-09 | 张九海 | Bitong capsule for treating numbness and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100379440C (en) | 2008-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1895556A (en) | Preparation for treating rheumatosis | |
| CN101077403A (en) | Plaster for treating retention of food and dysmenorrhea | |
| CN1211103C (en) | Oral taken and external use medicine for antirheumatism and stopping numbness pain | |
| CN1291489A (en) | Chinese medicine for treating baby pneumonia | |
| CN1833583A (en) | Health medicinal pillow | |
| CN1425394A (en) | Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method | |
| CN1231235C (en) | Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method | |
| CN1289114C (en) | Arthralgia pain treating bolus and its prepn | |
| CN1290550C (en) | Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof | |
| CN1092981C (en) | Medicine for curing arthralgia-syndrome resulted from wind,cold and dampness and its preparation method | |
| CN101049381A (en) | External Chinese traditional medicine for treating acne, and preparation method | |
| CN1843421A (en) | Rheumatoid disease treating medicine | |
| CN1748746A (en) | Chinese medicinal preparation for treating rheumatism, rheumatoid and hyperosteogeny and preparing method | |
| CN1640451A (en) | Medicinal composition for relieving itching | |
| CN1539455A (en) | Medical combination possessing effect for turning cancer off and rejuvenation | |
| CN108126024A (en) | A kind of pharmaceutical composition for treating rheumatoid arthritis | |
| CN1285380C (en) | Chinese patent medicines for treating chronic superficial gastritis (epigastric pain) and preparation method thereof | |
| CN1517115A (en) | Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation | |
| CN1903354A (en) | Traditional Chinese medicine for treating lumbago and skelalgia | |
| CN1095381C (en) | Method for preparing medicine for curing gastropathy | |
| CN1919260A (en) | Tranquilization, stomach nourition, and beauty treatment capsule and its preparation method | |
| CN1720938A (en) | Medicine for treating rheumatic arthritis and ankylosing spondylitis and its preparing process | |
| CN1241580C (en) | Medicinal composition for treating hypersteogeny | |
| CN1314160A (en) | Oral pill for curing diabetes and its complication | |
| CN1171598C (en) | Rheumatism treating nux vomica medicine powder |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180808 Address after: 437021 Xianning Matang Rheumatism Hospital, Xianning, Hubei 2 Patentee after: Xianning Matang Rheumatism Hospital Limited Address before: 437021 rheumatology specialist hospital, 5 Zeng Pu street, Ma Tang, Xianning, Hubei Patentee before: Zhen Shuiqing |
|
| TR01 | Transfer of patent right | ||
| CX01 | Expiry of patent term |
Granted publication date: 20080409 |
|
| CX01 | Expiry of patent term |