CN1318076C - Quick effective heat-reducing and bone numbness releasing medicine - Google Patents

Quick effective heat-reducing and bone numbness releasing medicine Download PDF

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Publication number
CN1318076C
CN1318076C CNB2003101101533A CN200310110153A CN1318076C CN 1318076 C CN1318076 C CN 1318076C CN B2003101101533 A CNB2003101101533 A CN B2003101101533A CN 200310110153 A CN200310110153 A CN 200310110153A CN 1318076 C CN1318076 C CN 1318076C
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ankylosing spondylitis
present
grams
medicine
blood
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CN1613479A (en
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赵信晔
阎举
阎保营
蒋付德
阎凤宝
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Abstract

The present invention discloses a quick acting heat reducing and bone-numbness releasing medicine for treating ankylosing spondylitis and juvenile ankylosing spondylitis. The present invention is proportionally prepared from thirteen kinds of traditional Chinese medicines, such as radix polygoni multiflori preparata, white paeony root, etc., and the traditional Chinese medicines are prepared into capsules or tablets by processing or extracting. The present invention has no toxic or side effect by oral administration, and has the effects of clearing heat and removing toxicity and enriching yin and nourishing the blood; with the present invention, patients with ankylosing spondylitis and juvenile ankylosing spondylitis can be healed in the early phase, the metaphase development of ankylosing spondylitis and juvenile ankylosing spondylitis is controlled, and the symptoms of ankylosing spondylitis and juvenile ankylosing spondylitis in the late phase are improved; the present invention is particularly suitable for intractable fever and severe pain, which are caused by juvenile ankylosing spondylitis; the present invention solves the problem that at present, no specific medicine for treating ankylosing spondylitis and juvenile ankylosing spondylitis exists; the present invention also has good curative effect on joint diseases, such as infectious arthritis, etc.

Description

A kind of medicine for the treatment of ankylosing spondylitis
Technical field the present invention relates to a kind of oral medicine for the treatment of flank pain, and relating in particular to pure Chinese medicine is a kind of medicine for the treatment of ankylosing spondylitis that raw material is made.
The background technology ankylosing spondylitis is each joint of a kind of spinal column, the disease that comprises sacroiliac joint, zygapophysial joints, costovertebral joints and joint surrounding tissue aggressive inflammation, late period, bone fusion, ligamentous ossification took place in each joint, spinal column is spasticity, and China patient reaches more than 400 ten thousand people.
People are understanding never in the past, and the ankylosing spondylitis of morbidity childhood makes ten hundreds of this class patients cast deformity before growing up entering, and childhood, ankylosing spondylitis was the modal a kind of joint disease of child.
Modern medicine thinks that the cause of disease of ankylosing spondylitis is likely the comprehensive function of genetic factors and environmental factors and causes.
The traditional Chinese medical science claims that primary disease is " rheumatism involving the bone ", and " numbness " is the obstructed meaning of impatency, is by the damp and hot heresy invasion and attack human body of wind and cold, resistance amenorrhea network, and QI and blood is not smooth, stagnation of blood stasis, mechanism of qi can not pass through, and " stagnation of QI and blood may bring about pain ".
Etiology and pathogenesis: how because of the Liver and kidney asthenia of essence and blood, or the quality deficiency of YIN, in deficiency-heat is arranged, bring out down and because of a primary disease in factors such as the damp and hot heresies of wind and cold.The basic pathogenesis characteristics are: phlegm and blood stasis, numbness resistance blood vessels, coldheat complex, vital QI being weakened and pathogen being violent.Cardinal symptom: waist, lower limb exercise are limited, and with backache, skelalgia is double mutually sees, the hypnalgia play, deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, buttocks, thigh or Calf muscle atrophy, hip joint gap turn narrow and fuzzy, cartilage destruction, bone trabecula passes through, so that bony ankylosis, permanent function of joint forfeiture takes place, and very then causes hyperosteogeny.
Especially childhood ankylosing spondylitis, obstinate heating, lumbago and skelalgia be present in primary disease all the time, sustainable several years; Patient's fever is high more, and the persistent period is long more, and PD is heavy more, and prognosis is poor more.Finally cause lumbar tetanic, hip joint destroys and deformity. and internal organs can take place and get involved and threat to life in severe patient.
The Chinese medical discrimination typing: wind-cold damp pathogen is attacked outward, white and thin fur, floating and tense pulse; Deficiency of kidney-essence, light red tongue, deep-thready pulse; Stagnation of blood stasis, body of the tongue has ecchymosis, thready and hesitant pulse; Damp and hot invade excessive, red tongue, thick and greasy fur, soft and rapid pulse.
Ankylosing spondylitis, childhood, ankylosing spondylitis if can obtain early diagnosis and early treatment, and effect is gratifying, but does not also have to effect a radical cure at present the specific drug of primary disease.The Western medicine anti-inflammation and analgesic drugs only can antiinflammatory and pain relieving, and the state of an illness is not had control action.Many untoward reaction can appear in a large amount of corticosteroids medicines that use, and disable or bring life danger.Change the medicine sulfasalazine and the methotrexate of the course of disease, might control the disease progression of ankylosing spondylitis childhood, but onset is slow, usually in 2-3 month onset of taking medicine.This class medicine has or not reverse effect to the middle and advanced stage pathological changes that bone destruction takes place, and still doubts at present.The subject matter of new Chinese medicine is how to cure by early metaphase, controls and improves the symptom in late period, and be very important key.
Summary of the invention the purpose of this invention is to provide a kind of medicine for the treatment of ankylosing spondylitis, has heat-clearing and toxic substances removing, the effect of nourishing YIN and benefiting blood, oral rapid-action, have no side effect, can effect a radical cure ankylosing spondylitis, the intractable heating of ankylosing spondylitis childhood that especially suits, lumbago and skelalgia.
Technical scheme of the present invention realizes in the following manner:
A kind of medicine for the treatment of ankylosing spondylitis is the medicine of making after first Chinese medicinal formulae processing or the refinement, and its prescription is: Radix Polygoni Multiflori Preparata 300 grams, the Radix Paeoniae Alba 200 grams, Radix Salviae Miltiorrhizae 280 grams, Herba Taxilli 280 grams, Cortex Phellodendri 120 grams, the Rhizoma Anemarrhenae 150 grams, Herba Patriniae 280 grams, Semen Coicis 200 grams, Radix Cyathulae 90 grams, Rhizoma Cibotii (remove floss) 150 grams, Rhizoma Smilacis Chinensis 280 grams, Pericarpium Citri Reticulatae 90 grams, Radix Glycyrrhizae 60 grams.
This prescription 13 flavor Chinese medicines are formed in proportion.
According to the ratio deal between this prescription medicine and medicine, promptly relative dosage after processing or the refinement, is made capsule or tablet, for oral.
We are the agent for the treatment of both the principal and the secondary aspects of a disease at the same time, since caused by liver and kidney deficiency, weakened defensive QI, and the heresy that wind and cold is damp and hot is invaded in an opponent's defence between meridians, joint, muscles and bones; Or arthromyodynia is with the passing of time, undermines Liver and kidney, asthenia of essence and blood, and deficiency in origin and excess in superficiality, the domination of pathogen causes pain; So reinforcement and elimination in combination is the rule of treatment of primary disease.Heat-clearing and toxic substances removing, nourishing YIN and benefiting blood are concrete method of treatment.The property of side's Chinese medicine is worked according to his ability, and the person of attacking must attack by force, a little less than benefit person must mend; The Radix Polygoni Multiflori Preparata nourishing the blood and yin, liver and kidney tonifying, removing toxicity for eliminating carbuncles, controlling lumbar and back pain is monarch drug.Radix Paeoniae, Radix Salviae Miltiorrhizae, parasitic nourishing the blood and yin are ministerial drug, with the principal drug assistance liver and kidney tonifying, and the power of nourishing the liver blood, the blood circulation promoting and blood stasis dispelling of holding concurrently again, removing heat from blood eliminating carbuncle, wind-damp dispelling, the merit of strong waist knee joint.Play main therapeutical effect at main disease and primary symptom.Cortex Phellodendri, Rhizoma Anemarrhenae consolidating YIN and yin nourishing and usefulness have heat clearing and damp drying, the effect of yin nourishing pathogenic fire reducing.Herba Patriniae, Semen Coicis heat-clearing and toxic substances removing, channels sootheing and network vessel quickening, stasis-dispelling and pain-killing.Radix Cyathulae, Rhizoma Cibotii, Rhizoma Smilacis Chinensis removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling, strong waist knee joint, particularly speciality of spinal column and arthrodynia of extremities is controlled in sharp joint. and Pericarpium Citri Reticulatae is amusing and Wen Huashui is wet, making wet going and expectorant disappears, and more than is adjuvant drug.Cooperate monarch-minister drug to strengthen therapeutical effect.Radix Glycyrrhizae and medicine are messenger drug, and full monarch's side one minister one assistant one makes to be share, to reach heat-clearing and toxic substances removing, the effect of nourishing YIN and benefiting blood.
Good effect of the present invention is:
Pure Chinese medicine cost is low, and crude drug source is wide, oral having no side effect, and more the back is difficult for recurrence, suits to take for a long time.Has heat-clearing and toxic substances removing, the effect of nourishing YIN and benefiting blood.Can eliminate the pro-inflammatory cytokine of ankylosing spondylitis, the infringement of pain factor pair human body.Can regulate body's immunity and internal organs battalion and defend function, improve blood circulation.To the primary disease deficiency of kidney-essence, stagnation of blood stasis, the damp and hot patient who invades excessive type, but early metaphase cure, control and improve primary disease symptom in late period, solved the problem that present treatment ankylosing spondylitis does not have specific drug.Be particularly useful for intractable heating, the lumbago and skelalgia of ankylosing spondylitis childhood, effect is remarkable.This medicine also has better curative effect to joint diseases such as infective arthritis, rheumatic arthritis.
Below with regard to the nature and flavor of this prescription 13 flavor Chinese medicines, return through and function be further described:
Radix Polygoni Multiflori hardship, puckery, tepor.Return liver, kidney channel.Nourishing the blood and yin, liver and kidney tonifying, removing toxicity for eliminating carbuncles.Main platform blood deficiency and yellow complexion, the Liver and kidney damage of essence deficiency of YIN, carbuncle sore scrofula, lumbar and back pain.Attention: nourishing the blood and yin should be made usefulness.
Radix Paeoniae Alba hardship, acid are slightly cold.Return liver, spleen channel.Nourish blood and seek relieving spasm to stop pain, arresting sweating suppressing the hyperactive liver.Cure mainly that blood deficiency is cloudy loses, night sweat spontaneous perspiration, contraction is anxious disease such as have a pain.Attention: anti-Rhizoma et radix veratri (Radix Rhizoma Veratri).
The Radix Salviae Miltiorrhizae hardship is slightly cold.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, the removing heat from blood eliminating carbuncle, nourishing blood to tranquillize the mind cures mainly the heat in blood stasis of blood and stagnates, stiffness along the spinal column pain, skin infection carbuncle.Attention: anti-Rhizoma et radix veratri (Radix Rhizoma Veratri), the careful clothes of anemia of pregnant woman
The Herba Taxilli hardship, flat.Return liver, kidney channel.Invigorating the liver and kidney, beneficial blood vessels, wind-damp dispelling.Cure mainly rheumatic Bi syndrome, children's's back rigidity, the soreness of the waist and knees of deficiency of the liver and kindey.
The Cortex Phellodendri hardship, cold.Return kidney, bladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.Cure mainly damp-heat dysentery, the low grade fever hectic fever of hyperactivity of fire caused by deficiency of YIN, furuncle carbuncle, sufficient swelling and pain in knee.
Rhizoma Anemarrhenae hardship, sweet, cold.Return lung, stomach, kidney channel.Clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, cure mainly calentura hyperpyrexia excessive thirst, hectic fever hectic fever due to YIN-deficiency night sweat.Attention: Deficiency and coldness of spleen and stomach, the loose stool person prohibits clothes.Should use unpeeled RHIZOMA ANEMARRHENAE.
Herba Patriniae suffering, hardship, cold.Return stomach, large intestine, Liver Channel.Heat-clearing and toxic substances removing, the evacuation of pus of invigorating blood circulation.Cure mainly the pyretic toxicity carbuncle, the heat in blood stasis of blood stagnates, malicious wind insensitive impediment.
Semen Coicis is sweet, light, is slightly cold.Return spleen, stomach, lung meridian.The dampness removing spleen invigorating, clearing away heat and discharging pus, arthralgia relieving by relaxing muscles and tendons.Cure mainly edema, dysuria, hygropyrexia, arthralgia chiefly caused by damp pathogen, lumbar and back pain.Attention: the careful usefulness of anemia of pregnant woman.
Sweet, the little hardship of Radix Cyathulae, flat.Return liver, kidney channel.Blood circulation promoting and blood stasis dispelling, the sharp numbness of collateral dredging, inducing diuresis for treating stranguria syndrome is apt to dead blood between the tonneau waist, and waist and knee was more special than other blood stasis dispelling medicine effect due to blood stasis, dead blood were blocked.Cure mainly the blood stasis amenorrhea, rheumatic arthralgia, pyretic stranguria.Attention: anemia of pregnant woman and menorrhagia person's forbidding.
Rhizoma Cibotii hardship, sweet, temperature.Return liver, kidney channel.Invigorating the liver and kidney, wind-damp dispelling, strong waist knee joint.Cure mainly the lumbago due to renal deficiency back rigidity.Attention: remove golden yellow fine hair.Should use ripe Rhizoma Cibotii.
Rhizoma Smilacis Chinensis is sweet, sour.Tepor.Return liver, kidney channel.Expelling wind and removing dampness, removing toxicity for eliminating carbuncles.Cure mainly migratory arthralgia, lumbar and back pain, diseases such as pyretic toxicity carbuncle sore.
Pericarpium Citri Reticulatae suffering, hardship, temperature.Return spleen, lung meridian.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly the distension and fullness of the chest and abdomen anorexia.Attention: Chen Jiuzhe is good.
Radix Glycyrrhizae is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine.Cure mainly deficiency of heart-QI, the anxious pain of pyretic toxicity carbuncle sore and extremity contraction.Attention: anti-Radix Kansui, the Radix Euphorbiae Pekinensis, Flos Genkwa, Sargassum.
Below just a kind of function for the treatment of the medicine of ankylosing spondylitis of the present invention, cure mainly etc. and to do an explanation:
[function cures mainly] heat-clearing and toxic substances removing, nourishing YIN and benefiting blood.Be used for ankylosing spondylitis, the fever that childhood, ankylosing spondylitis caused, lumbago and skelalgia, buttocks, thigh or Calf muscle atrophy, redness and swelling of joints, also can be used for joint diseases such as infective arthritis and rheumatic arthritis at diseases such as deformity.
13 flavors such as [medicine composition] Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, Cortex Phellodendri, the Rhizoma Anemarrhenae, Radix Cyathulae.
[character] this product is brown, gas perfume (or spice), mildly bitter flavor, little sweet.
[effect classification] this product is orthopaedics, lumbago and skelalgia and rheumatism class nonprescription drugs medicine.
The each 3-6 gram of [usage and dosage] oral (crude drug in whole), 2-3 time on the one or follow the doctor's advice, the child is cut down according to the circumstance.Two months is a course of treatment.
[points for attention] child, be not taken by pregnant women.Deficiency and coldness of spleen and stomach, the careful usefulness of loose stool person.Period in a medicine is avoided sitting excessive drinking and work and rest mistake degree.
[prescription dosage form] capsule or tablet.
A kind of medicine for the treatment of ankylosing spondylitis of specific embodiment the present invention, its specific embodiment is clinical practice, is described below:
Lift at one of [case 1] the inventor Yan, man, 23 years old now.Suffer from ankylosing spondylitis childhood in the time of 12 years old, long-term intractable low grade fever, spontaneous sweating, the hip arthralgia, mistaken diagnosis is a bone tuberculosis, delay treatment 4 years; Sb.'s illness took a turn for the worse because of dysentery causes in the back, hyperpyrexia occurs, severe pain, General Symptomies such as hip joint destruction.When critically ill, take diffusing Liu of we according to quantity, body temperature are normal after two weeks, and doing well,improving adheres to taking rehabilitation in four months.The period in a medicine no side effects.
[case 2] Zhang, the man, 43 years old now, right knee joint congestion and swelling pain, mistaken diagnosis is a rheumatism, because of the life-time service corticosteroid drug, edema was liied in bed 4 years from head to foot.Sb.'s illness took a turn for the worse in 1999, lives the county hospital, is diagnosed as the Fructus Vins coccus and infects, and used import medicine Ceftriaxone continuously 8 days, no obvious curative effects, and low grade fever does not move back.Took our powder 12 days, body temperature is normal, but out-of-bed activity; Adhered to taking three months, in conjunction with tempering recovery from illness.Can be as the muscular labor of normal person's dry weight.Take according to quantity and have no adverse reaction.

Claims (2)

1, a kind of medicine for the treatment of ankylosing spondylitis is characterized in that it is by Radix Polygoni Multiflori Preparata 300 grams, the Radix Paeoniae Alba 200 grams, Radix Salviae Miltiorrhizae 280 grams, Herba Taxilli 280 grams, Cortex Phellodendri 120 grams, the Rhizoma Anemarrhenae 150 grams, Herba Patriniae 280 grams, Semen Coicis 200 grams, Radix Cyathulae 90 grams, Rhizoma Cibotii 150 grams of remove floss, Rhizoma Smilacis Chinensis 280 grams, Pericarpium Citri Reticulatae 90 grams, Radix Glycyrrhizae 60 grams are formed.
2, medicine according to claim 1 is characterized in that it is capsule or tablet.
CNB2003101101533A 2003-11-03 2003-11-03 Quick effective heat-reducing and bone numbness releasing medicine Expired - Fee Related CN1318076C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435561A (en) * 2014-08-29 2015-03-25 刘天峰 Traditional Chinese medicine oral solution for treating infectious arthritis and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1099983A (en) * 1993-09-09 1995-03-15 袁双田 Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same
CN1146343A (en) * 1995-09-25 1997-04-02 石建民 External compress paste for discopathy
CN1425394A (en) * 2001-12-11 2003-06-25 镇水清 Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1099983A (en) * 1993-09-09 1995-03-15 袁双田 Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same
CN1146343A (en) * 1995-09-25 1997-04-02 石建民 External compress paste for discopathy
CN1425394A (en) * 2001-12-11 2003-06-25 镇水清 Bolus for eliminating arthralgia and activating energy flow in channels and collaterals and its preparing method

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