CN104435561A - Traditional Chinese medicine oral solution for treating infectious arthritis and preparation method thereof - Google Patents
Traditional Chinese medicine oral solution for treating infectious arthritis and preparation method thereof Download PDFInfo
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- CN104435561A CN104435561A CN201410436199.2A CN201410436199A CN104435561A CN 104435561 A CN104435561 A CN 104435561A CN 201410436199 A CN201410436199 A CN 201410436199A CN 104435561 A CN104435561 A CN 104435561A
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Abstract
The invention discloses a traditional Chinese medicine oral solution for treating infectious arthritis. The oral solution is prepared from the following medicinal raw materials in parts by weight: 9-18 parts of artemisia anomala, 10-30 parts of astragalus membranaceus, 5-9 parts of drynaria rhizome, 10-15 parts of sangusis draconis, 10-20 parts of angelica sinensis, 9-20 parts of honeysuckle, 4-9 parts of salvia miltiorrhiza, 3-12 parts of caulis akebiae, 10-25 parts of safflower carthamus, 4-10 parts of zaocys dhumnade, 3-9 parts of catechu and 3-9 parts of cassia twig. The traditional Chinese medicine oral solution has a remarkable effect on infectious arthritis, and can be used for relieving pain, sterilizing, diminishing inflammation, relaxing the muscles, stimulating the blood circulation, regulating qi and blood and improving weak constitution of a patient due to long-time pain. The oral solution is mainly prepared from local common medicinal materials with low prices, and can be reducing the economic burden of patients.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of Chinese medicine oral liquid for the treatment of infective arthritis and preparation method thereof.
Background technology
The infection of joint is the antibacterial deriving from synovial membrane or periarticular tissue, the inflammation that fungus or virus cause.
1. acute infective arthritis: can be caused by antibacterial or viral infection.(1) adult commonly Neisseria gonorrhoeae as pathogen.It expands to some hands Minor articulus, wrist, elbow, knee joint and ankle joint from infection mucous membrane surface (cervix uteri, rectum, pharynx).Axial sketelon joint is less to be involved.(2) Nongonococcal arthritis is many by staphylococcus aureus, streptococcus and gram negative bacteria, as enterobacteria, bacillus pyocyaneus, serratia marcecens cause.(3) staphylococcus aureus and B group B streptococcus infect and are more common in neonate and children more than 2 one full year of life.(4) infection of joint anaerobe often infects (5% ~ 10%) with facultative or aerobe, as staphylococcus aureus, and epidermis streptococcus and escherichia coli.(5) by the infection of joint that causes after biting many by gram negative bacteria as Type B streptococcus, oral cavity anaerobium (as clostruidium, streptococcus, bacteroid) causes.The infection of joint caused after animal bite is often staphylococcus aureus or mouth-flora.(6) in HIV patient, the infection of joint is by staphylococcus aureus, and streptococcus, salmonella causes.HIV patient can have reiter syndrome, relapsing arthritis, HIV dependency arthritis and arthralgia.HIV patients survive is more of a specified duration, mycobacteria, and the infection chance of fungus and rare conditioned pathogen is also more.(7) virus of acute arthritis is caused to comprise assays for parvovirus B 19, HBV, HCV, rubella virus (actute infection and immunity inoculation after) and togavirus.Chickenpox virus, parotid gland virus (adult), adenovirus, Coxsackie virus (A9, B2, B3, B4, B6); Epstein-Barr virus also with arthralgia, arthritis is relevant, and with pre biooxidation than more easily causing polyarthritis.
2, chronic infectional arthritis: chronic arthritis can by mycobacteria, and fungus and some other pathogenic more weak antibacterial cause.As mycobacterium tuberculosis, Mycobacterium marinum, mycobacterium kansasii, Candida, coccidioides immitis belongs to, Histoplasma capsulatum, Cryptococcus histolyticus, the raw bacterium of dermatitis tooth, Sporothrix schenckii Pseudomonas, aspergillosis, actinomyces israelii and Brucella.Within having patient articular's replacement postoperative infection of 2/3 to occur in 1 year, this may be that pneumonia, dentistry infects or UTI because operation technique introducing antibacterial or postoperative bacteriological infection are as skin infection.
Clinical manifestation: suffer from arthroncus, burning pain, a large amount of serosity of articular cavity inner accumulated, cellulosic or purulence transudate, joint capsule expands, by being pressed with fluctuation.The lame shape of suffering limb, often with the rising of body temperature; Prolonged then articular cartilage damage, subchondral bone is etched, ossa articularia periphery hyperosteogeny, and synovial membrane thickens; Later stage can develop into fibroid or the healing of bone joint, ankylosis or dead joint.
The Chinese medicine that patent discloses a kind for the treatment of of arthritis of Authorization Notice No. CN 102302604 B (application number 201110230913.9), it is characterized by, its activity is divided into and is made up of the raw material of following parts by weight: 12 parts, Semen Persicae, 12 parts, Flos Carthami, Radix Rehmanniae Preparata 20 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, Periostracum Cicadae 12 parts, the Radix Angelicae Dahuricae 9 parts, Radix Cynanchi Atrati 15 parts, 12 parts, Poria, Fructus Ligustri Lucidi 20 parts, Herba Leonuri 20 parts, Radix Salviae Miltiorrhizae 15 parts, Bombyx Batryticatus 10 parts, Caulis Spatholobi 30 Fen, female ground beetle 12 parts, Herba Lycopodii 15 parts, Rhizoma Cimicifugae 15 parts, Cortex Moutan 15 parts.The Chinese medicine that patent discloses a kind for the treatment of of arthritis of application publication number CN 103417925 A (application number 201210168748.3), is characterized in that it is made up of the component of following weight portion: Rhizoma Zingiberis Recens 4-6, brown sugar 4-6.
Summary of the invention
For the present situation of existing treatment infective arthritis deficiency, an object of the present invention is the Chinese medicine oral liquid providing treatment infective arthritis, has easy absorption, bactericidal effect is good, the feature that pain relieving is fast, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine oral liquid.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The Chinese medicine oral liquid for the treatment of infective arthritis, each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 9-18, Radix Astragali 10-30, Rhizoma Drynariae 5-9, Sanguis Draxonis 10-15, Radix Angelicae Sinensis 10-20, Flos Lonicerae 9-20, Radix Salviae Miltiorrhizae 4-9, Caulis Akebiae 3-12, Flos Carthami 10-25, ophidia 4-10, catechu 3-9, Ramulus Cinnamomi 3-9.
The Chinese medicine oral liquid for the treatment of infective arthritis, preferred scheme is, each crude drug is as follows, be weight portion: Herba Artemisiae Anomalae 13-15, Radix Astragali 15-25, Rhizoma Drynariae 6-8, Sanguis Draxonis 12-14, Radix Angelicae Sinensis 13-18, Flos Lonicerae 13-19, Radix Salviae Miltiorrhizae 5-7, Caulis Akebiae 5-10, Flos Carthami 15-20, ophidia 6-9, catechu 5-8, Ramulus Cinnamomi 5-7.
The Chinese medicine oral liquid for the treatment of infective arthritis, better preferred scheme is that each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 14, the Radix Astragali 20, Rhizoma Drynariae 7, Sanguis Draxonis 13, Radix Angelicae Sinensis 15, Flos Lonicerae 16, Radix Salviae Miltiorrhizae 6, Caulis Akebiae 7,18 parts, Flos Carthami, ophidia 8, catechu 6, Ramulus Cinnamomi 6.
The preparation method of above-mentioned Chinese medicine oral liquid, preparation process is as follows:
(1) decaptitated by ophidia, the block being cut into 0.5-1.5cm (preferred 1cm) puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, soak 1-3 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 1-5 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 10-20 hour (preferably 15 hours), and taking-up is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 1-5 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10-30 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30-50 minute slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) step (2) gained smalls is joined in step (3) gained mixing filtrate; be placed in marmite and add Apis; slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume; cease fire and leave standstill 1-5 hour, get supernatant and bottle and obtain Chinese medicine oral liquid.
The preparation method of foregoing Chinese medicine oral liquid, the consumption of step (1) jowar wine is that the 2-6 of the total consumption of ophidia and Radix Salviae Miltiorrhizae is doubly (preferred, the consumption of jowar wine is 3-5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, more preferably good, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae).
The preparation method of foregoing Chinese medicine oral liquid, step (1) drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, and stir-fry 2-4 minute fast, (preferably drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes).
The preparation method of foregoing Chinese medicine oral liquid, the consumption of step (2) white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, doubly (preferred, the consumption of white vinegar is Herba Artemisiae Anomalae to the 1-5 of Rhizoma Drynariae and Sanguis Draxonis gross weight, the Radix Astragali, doubly, be more added with choosing, the consumption of white vinegar is Herba Artemisiae Anomalae for the 2-4 of Rhizoma Drynariae and Sanguis Draxonis gross weight, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 3 times).
The preparation method of foregoing Chinese medicine oral liquid, step (3), after slightly vexed 2-4 hour, decocts with water 2 times, intense fire is fried open for the first time, turns and (preferably after slightly vexed 3 hours, decocts with water 2 times in 15-25 at a simmer minute, intense fire is fried open for the first time, turns 20 minutes at a simmer).
The preparation method of foregoing Chinese medicine oral liquid, step (3) low baking temperature that again adds water is decocted 35-45 minute (preferred, the low baking temperature that again adds water decocts 40 minutes slowly) slowly.
The preparation method of foregoing Chinese medicine oral liquid, step (4) is to be concentrated to 1/2 of original volume, ceases fire and leaves standstill 2-4 hour (preferred, to be concentrated to 1/2 of original volume, to cease fire and leave standstill 3 hours).
Instructions of taking: for making the present invention reach optimum therapeuticing effect, getting Chinese medicine oral liquid 40-60g of the present invention, washing open with boiled water, half an hour takes after breakfast, lunch and dinner 3 days is a course for the treatment of.
This Chinese medicine oral liquid, can not only pain relieving to the Be very effective of infective arthritis, can also bactericidal antiphlogistic, relaxing muscles and tendons to promote blood circulation, QI and blood regulating, improves the body constitution of patient's weakness because of chronic pain, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The Chinese medicine oral liquid for the treatment of infective arthritis, the pharmacological effect of each crude drug is respectively:
Herba Artemisiae Anomalae: have another name called Herba Artemisiae Anomalae grass, Herba Senecionis Scandentis is the wounded in the battle herb of Compositae sagebruss artemisia anomalas.The property of medicine: stem is cylindrical, surperficial brown color or brown-green, matter is hard and crisp, frangibility, the integrated spike panicle of head inflorescence, withered yellow, gas fragrance, bitter in the mouth, pungent, warm in nature.Composition: mainly containing arteanoflavone, tricin, apigenin, Palmic acid etc.Find according to modern pharmacological research, this medical instrument has effect of anti-hypoxia, blood circulation promoting and blood stasis dispelling, removing food stagnancy, hemostasia and detumescence, for amenorrhea due to stagnation of blood, and abdominal pain due to retention of food, hematuria, the diseases such as scald.
The Radix Astragali: the Radix Astragali, also known as Radix Astragali or northern Millefolium, also makes Radix Astragali or Radix astragali, one of conventional Chinese medicine, is the root of leguminous plant Radix Astagali or Radix Astragali.Nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.The Radix Astragali has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Rhizoma Drynariae: nature and flavor: bitter, temperature.Gui Jing: return kidney, Liver Channel.Effect: the kidney invigorating bone strengthening, continues and hinders pain relieving.Cure mainly: for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Sanguis Draxonis: nature and flavor: sweet, salty is flat.Gui Jing: GUIXIN, Liver Channel.Effect: removing blood stasis and relieving pain, hemostasia and promoting granulation.Cure mainly: lose for falling to flutter, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury.
Radix Angelicae Sinensis: call dryly to return, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, contain Radix Angelicae Sinensis, Radix Angelicae Gigatis, it is herbaceos perennial, and its root can be used as medicine, and is one of the most frequently used Chinese medicine.Sweet, pungent, warm, effect is classified: hematonic; Emmenagogue; Analgesic, effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation, cure mainly: all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Flos Lonicerae: have another name called Radix Ophiopogonis.Medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or is with the flower just opened.Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Radix Salviae Miltiorrhizae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.Cure mainly: for menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Caulis Akebiae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, small intestinal, urinary bladder channel.Effect: clearing away heart-fire, diuresis, stimulating milk secretion of stimulating the menstrual flow.Cure mainly: for irritable feverish sensation in the chest, larynx disease pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain, amenorrhea breast is few.
Flos Carthami: nature and flavor: pungent, temperature.Gui Jing: GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Cure mainly: for amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Ophidia: Zaocys, is commonly called as Zaocys, zaocys dhumnades, for Colubridae Zaocys belongs to the larger nonpoisonous snake of the bodily form, sweet, flat.Return Liver Channel.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Catechu: catechu, another name CATECHU, Catechu, gambier are pulse family albizzia plant catechu tree.Bitter, puckery, be slightly cold.Heat clearing away, promotes the production of body fluid, and reduces phlegm, sore, hemopoietic.For watery diarrhea, endo-enteritis, oral cavity ulceration, eczema, cough, knife injury is hemorrhage.
Ramulus Cinnamomi: nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, urinary bladder channel.Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Cure mainly: for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Chinese medicine oral liquid of the present invention is based on the principle of traditional Chinese medical herbal treatment infective arthritis.The Chinese medicinal material selected has bactericidal antiphlogistic, relaxing muscles and tendons to promote blood circulation, effect of pain relieving, and cheap, and long-term taking also can not cause the financial burden of patient, is to treat the ideal medicine of infective arthritis.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 treats the Chinese medicine oral liquid of infective arthritis, and each crude drug is as follows, is weight portion (getting 10g for every part): Herba Artemisiae Anomalae 9 parts, the Radix Astragali 10 parts, Rhizoma Drynariae 5 parts, Sanguis Draxonis 10 parts, Radix Angelicae Sinensis 10 parts, Flos Lonicerae 9 parts, Radix Salviae Miltiorrhizae 4 parts, Caulis Akebiae 3 parts, 10 parts, Flos Carthami, ophidia 4 parts, 3 parts, catechu, Ramulus Cinnamomi 3 parts.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment infective arthritis, step is:
(1) decaptitated by ophidia, the block being cut into 0.5cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 2 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 1 day, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 1 minute, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 10 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 1 times, takes out and is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 1 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite and add Apis, slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume, cease fire and leave standstill 1 hour, get supernatant and bottle and obtain Chinese medicine oral liquid.
Model case one Zou XX, man, 40 years old, Harbin, Heilungkiang personage, peasant, started from 2012, waist breakthrough pain also accompanies right lower extremity radiating pain, originally the symptom of cough is also had time, during stool, pain increases the weight of, right crus of diaphragm has feeling of numbness, difficulty in walking, sleeping at night is poor, go to local clinic to check and say the above-mentioned symptom that its fatigue causes, the medicine of some Conventional pain has been opened to it, and enjoin it to have a good rest, eat the medicine of 3 days, also sleep on time, but symptom has no improvement, so detailed inspection of just having gone large hospital to do, be prolapse of lumbar intervertebral disc on inspection after diagnosing, after treatment after a while, prolapse of lumbar intervertebral disc takes a turn for the better to some extent, but the knee joint swelling of patient, burning pain, go to check a large amount of serosity of articular cavity inner accumulated finding patient, be diagnosed as infective arthritis.
Take embodiment 1 gained Chinese medicine oral liquid, take 3 days arthralgias and alleviate, sensation swelling disappears; Take 10 days, pain disappears, and can normally walk; Continue to take 10 days as consolidating, drug withdrawal is so far without recurrence.
Embodiment 2 treats the Chinese medicine oral liquid of infective arthritis, and each crude drug is as follows, is weight portion (getting 15g for every part): Herba Artemisiae Anomalae 18 parts, the Radix Astragali 30 parts, Rhizoma Drynariae 9 parts, Sanguis Draxonis 15 parts, Radix Angelicae Sinensis 20 parts, Flos Lonicerae 20 parts, Radix Salviae Miltiorrhizae 9 parts, Caulis Akebiae 12 parts, 25 parts, Flos Carthami, ophidia 10 parts, 9 parts, catechu, Ramulus Cinnamomi 9 parts.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment infective arthritis, step is:
(1) decaptitated by ophidia, the block being cut into 1.5cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 6 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 3 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 5 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 20 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 5 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 5 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 30 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 50 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite and add Apis, slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume, cease fire and leave standstill 5 hours, get supernatant and bottle and obtain Chinese medicine oral liquid.
Embodiment 3 treats the Chinese medicine oral liquid of infective arthritis, and each crude drug is as follows, is weight portion (getting 20g for every part): Herba Artemisiae Anomalae 13 parts, the Radix Astragali 15 parts, Rhizoma Drynariae 6 parts, Sanguis Draxonis 12 parts, Radix Angelicae Sinensis 13 parts, Flos Lonicerae 13 parts, Radix Salviae Miltiorrhizae 5 parts, Caulis Akebiae 5 parts, 15 parts, Flos Carthami, ophidia 6 parts, 5 parts, catechu, Ramulus Cinnamomi 5 parts.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment infective arthritis, step is:
(1) decaptitated by ophidia, the block being cut into 0.8cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 3 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 1.5 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 2 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 13 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 2 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 2 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 13 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 35 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite and add Apis, slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume, cease fire and leave standstill 2 hours, get supernatant and bottle and obtain Chinese medicine oral liquid.
Model case two Zhu XX, female, 35 years old, Jinan City, Shandong Province personage.During motion, the gonalgia is unbearably, can not power-walking, bend over, legs become numb, creeps as Formica fusca, walking disorder, and even having occurred the symptom of walking lamely, is infective arthritis after diagnosing.See hospital of a lot of family, massaging and physiotherapeutical shop, clinic, all do not obtain satisfied therapeutic effect.
Take embodiment 3 gained Chinese medicine oral liquid, take 5 days, lower limb fiber crops symptom is alleviated to some extent; Take 10 days, walking of can having left the bed, limping symptom disappears substantially; Take 5 days as consolidating, appearance without any side effects during taking embodiment 3 gained Chinese medicine oral liquid.
Embodiment 4 treats the Chinese medicine oral liquid of infective arthritis, and each crude drug is as follows, is weight portion (getting 25g for every part): Herba Artemisiae Anomalae 15 parts, the Radix Astragali 25 parts, Rhizoma Drynariae 8 parts, Sanguis Draxonis 14 parts, Radix Angelicae Sinensis 18 parts, Flos Lonicerae 19 parts, Radix Salviae Miltiorrhizae 7 parts, Caulis Akebiae 10 parts, 20 parts, Flos Carthami, ophidia 9 parts, 8 parts, catechu, Ramulus Cinnamomi 7 parts.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment infective arthritis, step is:
(1) decaptitated by ophidia, the block being cut into 1.3cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 2.5 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 4 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 18 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 4 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 4 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 25 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 45 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite and add Apis, slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume, cease fire and leave standstill 4 hours, get supernatant and bottle and obtain Chinese medicine oral liquid.
Embodiment 5 treats the Chinese medicine oral liquid of infective arthritis, and each crude drug is as follows, is weight portion (getting 30g for every part): Herba Artemisiae Anomalae 14 parts, the Radix Astragali 20 parts, Rhizoma Drynariae 7 parts, Sanguis Draxonis 13 parts, Radix Angelicae Sinensis 15 parts, Flos Lonicerae 16 parts, Radix Salviae Miltiorrhizae 6 parts, Caulis Akebiae 7 parts, 18 parts, Flos Carthami, ophidia 8 parts, 6 parts, catechu, Ramulus Cinnamomi 6 parts.
The preparation method of the Chinese medicine oral liquid of above-mentioned treatment infective arthritis, step is:
(1) decaptitated by ophidia, the block being cut into 1cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 2 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 15 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 3 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 3 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 20 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 40 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite and add Apis, slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume, cease fire and leave standstill 3 hours, get supernatant and bottle and obtain Chinese medicine oral liquid.
The clinical practice of the Chinese medicine oral liquid of test example 1 embodiment 5 gained treatment infective arthritis: screen 300 routine patients in 4 hospitals, before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 gained Chinese medicine oral liquid, and matched group takes other medicine (medicine of the conventional therapy infective arthritis such as anti-inflammatory analgesic cream, antiphlogistic tissue regenerating ointment).Instructions of taking is: instructions of taking: for making the present invention reach optimum therapeuticing effect, getting Chinese medicine oral liquid 40-60g of the present invention, washing open with boiled water, after breakfast, lunch and dinner, half an hour takes, and within 3 days, is a course for the treatment of.Curative effect situation criterion: cure: malaise symptoms disappears completely, effectively: after taking this product, malaise symptoms alleviates or partial disappearance; Invalid: after taking this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take embodiment 5 product prolapse of lumbar intervertebral disc patient treatment outcome
Therapeutic effect: experimental group cures number 192 example, clinical effective 6 examples, total effective rate 99%, experimental group curative effect is apparently higher than matched group.
The Chinese medicine oral liquid for the treatment of infective arthritis, wherein Radix Astragali Flos Carthami is combined and is done monarch, and ministerial drug is Radix Angelicae Sinensis, Herba Artemisiae Anomalae, Flos Lonicerae, ophidia and Caulis Akebiae, and remaining is adjuvant drug; Monarch drug carries attending effectiveness in the present invention, all has effect of analgesic antiphlogistic, blood circulation promoting and blood stasis dispelling; Ministerial drug is the medicine that auxiliary monarch drug strengthens the main disease for the treatment of and main symptom; Adjuvant drug treatment is held concurrently disease, slows down the strong of monarch drug and ministerial drug; Medicine is made to play a part guiding drug.
Claims (10)
1. treat the Chinese medicine oral liquid of infective arthritis, it is characterized in that: each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 9-18, Radix Astragali 10-30, Rhizoma Drynariae 5-9, Sanguis Draxonis 10-15, Radix Angelicae Sinensis 10-20, Flos Lonicerae 9-20, Radix Salviae Miltiorrhizae 4-9, Caulis Akebiae 3-12, Flos Carthami 10-25, ophidia 4-10, catechu 3-9, Ramulus Cinnamomi 3-9.
2. the Chinese medicine oral liquid for the treatment of infective arthritis according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 13-15, Radix Astragali 15-25, Rhizoma Drynariae 6-8, Sanguis Draxonis 12-14, Radix Angelicae Sinensis 13-18, Flos Lonicerae 13-19, Radix Salviae Miltiorrhizae 5-7, Caulis Akebiae 5-10, Flos Carthami 15-20, ophidia 6-9, catechu 5-8, Ramulus Cinnamomi 5-7.
3. the Chinese medicine oral liquid for the treatment of infective arthritis according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 14, the Radix Astragali 20, Rhizoma Drynariae 7, Sanguis Draxonis 13, Radix Angelicae Sinensis 15, Flos Lonicerae 16, Radix Salviae Miltiorrhizae 6, Caulis Akebiae 7,18 parts, Flos Carthami, ophidia 8, catechu 6, Ramulus Cinnamomi 6.
4. the preparation method of the Chinese medicine oral liquid of the treatment infective arthritis according to any one of claim 1-3, is characterized in that: step is as follows:
(1) decaptitated by ophidia, the block being cut into 0.5-1.5cm (preferred 1cm) puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, soak 1-3 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 1-5 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 10-20 hour (preferably 15 hours), and taking-up is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Flos Lonicerae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Ramulus Cinnamomi add in step (1) gained filtrate, and mixing, after slightly vexed 1-5 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10-30 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30-50 minute slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) step (2) gained smalls is joined in step (3) gained mixing filtrate; be placed in marmite and add Apis; slow fire is decocted slowly; stir while decoct; to be concentrated to 1/2 of original volume; cease fire and leave standstill 1-5 hour, get supernatant and bottle and obtain Chinese medicine oral liquid.
5. the preparation method of Chinese medicine oral liquid according to claim 4, it is characterized in that: the consumption of step (1) jowar wine is that the 2-6 of the total consumption of ophidia and Radix Salviae Miltiorrhizae is doubly (preferred, the consumption of jowar wine is 3-5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, more preferably good, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae).
6. the preparation method of Chinese medicine oral liquid according to claim 4, it is characterized in that: step (1) drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 2-4 minute fast, (preferably drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes).
7. the preparation method of Chinese medicine oral liquid according to claim 4, it is characterized in that: the consumption of step (2) white vinegar is Herba Artemisiae Anomalae, the Radix Astragali, doubly (preferred, the consumption of white vinegar is Herba Artemisiae Anomalae to the 1-5 of Rhizoma Drynariae and Sanguis Draxonis gross weight, the Radix Astragali, doubly, be more added with choosing, the consumption of white vinegar is Herba Artemisiae Anomalae for the 2-4 of Rhizoma Drynariae and Sanguis Draxonis gross weight, the Radix Astragali, Rhizoma Drynariae and Sanguis Draxonis gross weight 3 times).
8. the preparation method of Chinese medicine oral liquid according to claim 4, it is characterized in that: step (3) is after slightly vexed 2-4 hour, decoct with water 2 times, intense fire is fried open for the first time, turn 15-25 at a simmer minute (preferably after slightly vexed 3 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 20 minutes at a simmer).
9. the preparation method of Chinese medicine oral liquid according to claim 4, is characterized in that: step (3) low baking temperature that again adds water is decocted 35-45 minute (preferred, the low baking temperature that again adds water decocts 40 minutes slowly) slowly.
10. the preparation method of Chinese medicine oral liquid according to claim 4, is characterized in that: step (4) is to be concentrated to 1/2 of original volume, ceases fire and leaves standstill 2-4 hour (preferred, to be concentrated to 1/2 of original volume, to cease fire and leave standstill 3 hours).
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1613479A (en) * | 2003-11-03 | 2005-05-11 | 阎凤宝 | Quick effective heat-reducing and bone numbness releasing medicine |
| CN1964730A (en) * | 2004-06-09 | 2007-05-16 | 深圳市前仁人科技开发有限公司 | Herbal compositions for prevention and treatment rheumatic and inflammatory diseases and method of preparing the same |
-
2014
- 2014-08-29 CN CN201410436199.2A patent/CN104435561A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1613479A (en) * | 2003-11-03 | 2005-05-11 | 阎凤宝 | Quick effective heat-reducing and bone numbness releasing medicine |
| CN1964730A (en) * | 2004-06-09 | 2007-05-16 | 深圳市前仁人科技开发有限公司 | Herbal compositions for prevention and treatment rheumatic and inflammatory diseases and method of preparing the same |
Non-Patent Citations (4)
| Title |
|---|
| 刘维: "《中西医结合风湿免疫病学》", 30 November 2009, 华中科技大学出版社 * |
| 周翠英: "《风湿病中西医诊疗学》", 28 February 1998, 中国中医药出版社 * |
| 胡荫奇: "《简明中西医结合风湿病学》", 28 February 2009, 科学技术文献出版社 * |
| 陈宏珪: "中医治疗感染性中毒性关节炎三例报告", 《新中医》 * |
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