CN1418668A

CN1418668A - Chinese patent drug for treating bone ache, and its prepn. method

Info

Publication number: CN1418668A
Application number: CN 02134197
Authority: CN
Inventors: 张家诚
Original assignee: GUIZHOU JIACHENG PHARMACEUTICAL CO Ltd
Current assignee: GUIZHOU JIACHENG PHARMACEUTICAL CO Ltd
Priority date: 2002-11-26
Filing date: 2002-11-26
Publication date: 2003-05-21
Anticipated expiration: 2022-11-26
Also published as: CN1181866C

Abstract

The preparation method of Chinese patent medicine capsule preparation for curing ostealgia includes the following steps: according to a certain weight mixing ratio pulverizing cinnamon bark into fine powder; decocting prepared aconite accessory tuber, prepared aconite main tuber; codonopsis root, Chinese angelica root, perpared whit4e peony root, epimedium and prepared frankincense in water, concentrating filtrate to obtain thick paste material, stirring it and cinnamon fine powder uniformly, reduced pressure drying at 80 deg.C, adding proper quantity of auxiliary, pulverizing, sieving and capsulizing so as to obtain the invented product.

Description

Chinese patent medicine of treatment osteodynia and preparation method thereof

Technical field: the present invention relates to a kind of Chinese patent medicine for the treatment of osteodynia and preparation method thereof, specifically is the preparation method of Chinese patent medicine and this medicine thereof of feedstock production with the Chinese herbal medicine.

Technical background: for the common limbs joint pain of people, miserable, numb, swelling, treatment of diseases such as hyperosteogeny, gonarthritis prior treatment method generally adopts therapy of combining Chinese and Western medicine, more oral pain relieving medicines, apply, paste some Chinese medicinal ointment, card etc. again, this method can the alleviating pain position pain, but effect is undesirable, can cause state of an illness outbreak repeatedly, prolongedly not heal, have a strong impact on health.

Summary of the invention: the objective of the invention is to: a kind of preparation method for the treatment of the Chinese patent medicine and this medicine thereof of osteodynia is provided, and product can be used in local arthralgia, joint stuffiness, numbness and the swelling etc. due to treatment yang deficiency cold-dampness type cervical vertebra and the gonarthrosis; The present invention constitutes like this: the Chinese patent medicine of this treatment osteodynia is the medicament of being made by the following weight proportion raw material: Radix Paeoniae Alba 140-180g, the Herba Epimedii 140-180g of the Radix Aconiti Lateralis Preparata 200-250g that concocted, the Radix Aconiti 100-130g that concocted, Cortex Cinnamomi 30-70g, Radix Codonopsis 140-180g, Radix Angelicae Sinensis 140-180g, parch, the Olibanum 100-130g that concocted; More specific prescription is Radix Aconiti Lateralis Preparata 222g, the Radix Aconiti 111g that concocted, Cortex Cinnamomi 56g, Radix Codonopsis 167g, Radix Angelicae Sinensis 167g, Radix Paeoniae Alba 167g, the Herba Epimedii 167g of parch, the Olibanum 111g that concocted that concocted; Medicament described in the present invention is the dosage form of any pharmaceutics regulation; The Chinese patent medicine preparation method of this treatment osteodynia, be according to weight proportion, Cortex Cinnamomi powder is broken into fine powder, the Olibanum of the Radix Paeoniae Alba of the Radix Aconiti Lateralis Preparata of concocting, the Radix Aconiti of concocting, Radix Codonopsis, Radix Angelicae Sinensis, parch, Herba Epimedii, the process of preparing Chinese medicine decocts with water secondary, each 1 hour, collecting decoction filters, and filtrate is concentrated into the thick paste shape, stir with Cortex Cinnamomi powder, drying under reduced pressure below 80 degrees centigrade adds the appropriate amount of auxiliary materials grinding and sieving, in incapsulating; This method also can adopt the active ingredient of Olibanum of the Radix Paeoniae Alba, Herba Epimedii, the process of preparing Chinese medicine of the Radix Aconiti Lateralis Preparata that prior art will concoct, the Radix Aconiti of concocting, Radix Codonopsis, Radix Angelicae Sinensis, parch to extract or concentrate, mix with the Cortex Cinnamomi that is ground into powder then, adopt routine techniques to be made into preparation.

Compared with prior art: the present invention can be used in the symptoms such as local arthralgia, joint stuffiness, numbness and swelling due to treatment yang deficiency cold-dampness type cervical vertebra and the gonarthrosis; Radix Aconiti Lateralis Preparata is hot dry strong in the side, walks and 12 warps of not keeping, pass through; Can mend the Yuanyang of any of several broadleaf plants down, by the cold-damp in the lining, the warming YANG of using is mended fire, dispersing cold for relieving pain; The Radix Aconiti expelling wind and removing dampness, antalgic, its effect and Radix Aconiti Lateralis Preparata are close, and only the merit of YANG invigorating is not as good as Radix Aconiti Lateralis Preparata, and the power of the blood stasis dispelling that dispels the wind then is victory than Radix Aconiti Lateralis Preparata, and the two share and brings out the best in each other; It is supporing yang that Cortex Cinnamomi is mended fire, and dispersing cold for relieving pain again can promoting the flow of QI in the collateral by warming the meridian, guiding fire to origin, and for slow, Radix Aconiti, Cortex Cinnamomi are share the merit that can help the pain relieving of Radix Aconiti Lateralis Preparata warming YANG to expel cold to the merit of its temperature compensation yang-energy than Radix Aconiti Lateralis Preparata; The Olibanum hardship lets out, hotly loose, temperature is logical, can declare logical active, activating blood circulation and dissipating blood stasis, the stasis of blood only purifies the blood then pain alive, clonic spasm of the muscle is stretched, and swells and ache to disappear, muscle is long, so the effect of the muscle of stretching pain relieving, detumescence and promoting granulation is arranged, share with Radix Aconiti, Radix Aconiti Lateralis Preparata, increases the power of its pain relieving; Be aided with Radix Codonopsis QI invigorating Gu Wei in the side, Radix Angelicae Sinensis, Radix Paeoniae Alba blood-supplementing blood-nourishing, promoting blood circulation and stopping pain makes the QI and blood that is checked by the cold-evil must mend fosterly, and QI and blood foot, anti-heresy are gone out, the meaning of residence strengthening vital QI to eliminate pathogenic factors; The sweet temperature of Herba Epimedii can kidney invigorating and YANG supporting, the Xin Wenneng wind dehumidifying of loosing, thus can kidney-replenishing, bone and muscle strengthening again can wind-damp dispelling, controls arthralgia pain, and it goes into kidney channel edge, and kidney governing bones can be with all medicines into sick institute, and complete square share played the merit of warming YANG to expel cold, benefiting QI for activating blood circulation, reducing swelling and alleviating pain altogether; Product has obtained the approval of national drug administration section and has produced and sold.

Modern medicine study proves: the main toxicity of Radix Aconiti, Radix Aconiti Lateralis Preparata is carried out the long period decoction in water after, it can be hydrolyzed to the less hydrolyzate of toxicity such as monoester Alkaloid, therefore, the Radix Aconiti of using among the we, Radix Aconiti Lateralis Preparata are process of preparing Chinese medicine processed goods, through processes such as decoction, heat dryings, and use amount is smaller, in the prescribed limit of country, so use rationally; In the Pharmacodynamic test of active extract of the product capsule preparations that is undertaken by Guiyang Medical College, the effect of this product obtains confirming.The instructions of taking of this product is: every day 3 times, each 4 capsules (symphysis medicine 7.01g/ time).

Embodiments of the invention 1: be that Cortex Cinnamomi 56g is pulverized, Radix Paeoniae Alba 167g, the Herba Epimedii 167g of the Radix Aconiti Lateralis Preparata 222g that concocted, the Radix Aconiti 111g that concocted, Radix Codonopsis 167g, Radix Angelicae Sinensis 167g, parch, the Olibanum 111g that concocted are decocted with water secondary, each 1 hour, collecting decoction filters, and filtrate is concentrated into the thick paste shape, stir with Cortex Cinnamomi powder, drying under reduced pressure below 80 degrees centigrade adds the appropriate amount of auxiliary materials grinding and sieving, in 666 capsules of packing into.

Embodiments of the invention 2: Cortex Cinnamomi 30g is pulverized, with Radix Paeoniae Alba 140g, the Herba Epimedii 140g of the Radix Aconiti Lateralis Preparata 200-250g that concocted, the Radix Aconiti 100g that concocted, Radix Codonopsis 140g, Radix Angelicae Sinensis 140g, parch, the Olibanum 100g that concocted; Decoct with water secondary, each 1 hour, collecting decoction filtered, and filtrate is concentrated into the thick paste shape, stirs with Cortex Cinnamomi powder, and drying under reduced pressure below 80 degrees centigrade adds the appropriate amount of auxiliary materials grinding and sieving, gets granule.

Embodiments of the invention 3: Cortex Cinnamomi 70g is pulverized, Radix Paeoniae Alba 180g, the Herba Epimedii 180g of the Radix Aconiti Lateralis Preparata 250g that concocted, the Radix Aconiti 130g that concocted, Radix Codonopsis 180g, Radix Angelicae Sinensis 180g, parch, the Olibanum 130g that concocted are adopted prior art: supercritical carbon dioxide extraction method extracts their active ingredient, concentrate, mix with the Cortex Cinnamomi that is ground into powder then, adopt routine techniques to be made into preparation.

Claims

1, a kind of Chinese patent medicine for the treatment of osteodynia, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: Radix Paeoniae Alba 140-180g, the Herba Epimedii 140-180g of the Radix Aconiti Lateralis Preparata 200-250g that concocted, the Radix Aconiti 100-130g that concocted, Cortex Cinnamomi 30-70g, Radix Codonopsis 140-180g, Radix Angelicae Sinensis 140-180g, parch, the Olibanum 100-130g that concocted.

2, according to the Chinese patent medicine of the described this treatment osteodynia of claim 1, it is characterized in that: more specific prescription is Radix Aconiti Lateralis Preparata 222g, the Radix Aconiti 111g that concocted, Cortex Cinnamomi 56g, Radix Codonopsis 167g, Radix Angelicae Sinensis 167g, Radix Paeoniae Alba 167g, the Herba Epimedii 167g of parch, the Olibanum 111g that concocted that concocted.

3, according to the Chinese patent medicine of claim 1,2 described this treatment osteodynia, it is characterized in that: described medicament is the dosage form of any pharmaceutics regulation.

4, a kind of Chinese patent medicine preparation method for the treatment of osteodynia, it is characterized in that: according to weight proportion, Cortex Cinnamomi powder is broken into fine powder, the Olibanum of the Radix Paeoniae Alba of the Radix Aconiti Lateralis Preparata of concocting, the Radix Aconiti of concocting, Radix Codonopsis, Radix Angelicae Sinensis, parch, Herba Epimedii, the process of preparing Chinese medicine decocts with water secondary, each 1 hour, collecting decoction filters, and filtrate is concentrated into the thick paste shape, stir with Cortex Cinnamomi powder, drying under reduced pressure below 80 degrees centigrade adds the appropriate amount of auxiliary materials grinding and sieving, in incapsulating.

5, according to the Chinese patent medicine preparation method of the described this treatment osteodynia of claim 4, it is characterized in that: the active ingredient of the Olibanum of the Radix Paeoniae Alba of the Radix Aconiti Lateralis Preparata that the employing prior art will be concocted, the Radix Aconiti of concocting, Radix Codonopsis, Radix Angelicae Sinensis, parch, Herba Epimedii, the process of preparing Chinese medicine extracts or concentrates, mix with the Cortex Cinnamomi that is ground into powder then, adopt routine techniques to be made into preparation.