CN1416892A - Compound medicine tablet of biological bacteria powder for treating dyspneic cough - Google Patents
Compound medicine tablet of biological bacteria powder for treating dyspneic cough Download PDFInfo
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- CN1416892A CN1416892A CN 01133663 CN01133663A CN1416892A CN 1416892 A CN1416892 A CN 1416892A CN 01133663 CN01133663 CN 01133663 CN 01133663 A CN01133663 A CN 01133663A CN 1416892 A CN1416892 A CN 1416892A
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- ganoderma
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- medicine tablet
- rhizoma coptidis
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Abstract
The compound medicine tablet has deactivated thallus, Chinese goldthread and glossy ganoderma as the main components. The deactivated thallus is staphylococcus albus and/or coliform bacteria. The optimal compounding composition in each 1000 tablets is deactivated thallus 25-45 billion, Chinese goldthread 100-200 g and glossy ganoderma 100-200 g. The compound medicine tablet is used in treating bronchitis, and the effective dosage is 2.5-250 hundred million thallus each Kg body weight every day.
Description
Technical field
The invention provides a kind of a kind of compound medicine tablet of biological bacteria powder for treating dyspneic cough that relates to, belong to the medicine class of preventing and treating chronic bronchitis, asthma, [be active component, prescription is main particularly to add Chinese medicine with the thalline of deactivation
Consist of the asthma quasi drugs that the thalline, Chinese medicine of some and implant that suitable adjuvant is formed combine.
Background technology
Bronchial asthma (Asthma) is the trachea chronic inflammatory disease that is participated in by multiple inflammatory cell such as eosinophilic granulocyte, mastocyte and T lymphocyte, this inflammation makes the susceptible person have airway hyperreactivity to various motivating factors, and can cause the air flue constriction, show as ictally pant, dyspnea, uncomfortable in chest or cough etc.Be everlasting night or (with) early morning outbreak, easily aggravation.Have more now extensively changeable reversibility flow limitation, but majority spontaneous remission or alleviate through treatment, and it is key character often with wheezing sound in the throat with airway allergy inflammation and airway hyperreactivity.At present, doctor trained in Western medicine thinks that main pathogenesis has: inherited genetic factors-asthma is a kind of polygenic inheritance disease that has family to assemble tendency; It is the pathophysiological basis that forms cough with asthma that neuroregulation mechanism-air flue autonomic nervous dysfunction causes airway hyper-reaction;
The traditional Chinese medical science thinks that the generation of asthma is by latent phlegm retaining in the lung, and because of inducements such as diseases caused by exogenous pathogenic factor, diet or emotion overstrain cause that consequently the mistake of stagnation of phlegm air flue lung is fallen, air flue is anxious, belongs to the disease of deficiency in origin and excess in superficiality more.In recent years, many scholars recognize that pathogenic factor such as stasis of blood expectorant, blood stasis, wind are the important pathogenesis of asthma, and " tri-layer " smelting iatreusiology of proposition asthma is said, set upright with smelting originally to train unit, whole conditioning is dug up the roots, divide lung, spleen, the smelting of kidney tri-layer to treat three void, reach the effect for the treatment of both the principal and secondary aspects of a disease.
Doctor trained in Western medicine is treated the smelting of chronic bronchitis, bronchial asthma does not at present still have the radical cure good recipe, and relief of symptoms is used aerosol, inhalant more, and treatment is based on the antiinflammatory spasmolytic, and effect is undesirable, and costs an arm and a leg,
Toxic and side effects is big, and for its acute attack of control and effectively minimizing recurrence rapidly, using has the Chinese and Western for the treatment of both the principal and secondary aspects of a disease effect in conjunction with medicine immeasurable prospect to be arranged.
The technology contents of invention
The purpose of this invention is to provide and a kind ofly relate to bio-pharmaceuticals and prevent the prescription of smelting bronchitis, asthma, effect both had been higher than the simple traditional Chinese medical science, was higher than simple doctor trained in Western medicine again, and easily produce, cost is low, steady quality, have no side effect again.
Compound medicine tablet of biological bacteria powder for treating dyspneic cough of the present invention, its main component comprise deactivation thalline, Rhizoma Coptidis, Ganoderma composition, and its proportioning is per 1000 and contains deactivation thalline 15,000,000,000,000-60,000,000,000,000, Rhizoma Coptidis 100-200g, Ganoderma 100-200g.
Described compound medicine tablet of biological bacteria powder for treating dyspneic cough, its deactivation thalline are Staphylococcus albus and or escherichia coli.
Described compound medicine tablet of biological bacteria powder for treating dyspneic cough, the optimum of the proportioning of its deactivation thalline, Rhizoma Coptidis, Ganoderma are per 1000 and contain inactivated bacteria 25,000,000,000,000-45,000,000,000,000, Rhizoma Coptidis 100-200g, Ganoderma 100-200g.
This compound medicine tablet of biological bacteria powder for treating dyspneic cough is used for anti-smelting bronchitis, related prescription component can be used in combination by its pharmaceutically acceptable any different proportion, and its effective dose is that each thalline is respectively every day 2.5 hundred million-25,000,000,000/Kg body weight.
The advantage of above-mentioned composition compound recipe cough with asthma tablet is: play a kind of effect that makes immune system activation, make patient self produce immunity, anti-smelting asthma is had very good effect.Can be with above-mentioned related
The component of active component is according to the pharmaceutically acceptable different proportion combination in any of above-mentioned form.Said composition can be by Orally administered, and its each thalline effective dose is respectively hundred million/Kg body weight every day 0.25 hundred million-2500, and preferred dose is respectively every day 2.5 hundred million-25,000,000,000/Kg body weight.
The present invention be advantageous in that the Chinese and Western combination, off the beaten track, raw material is cheap and easy to get, and easy, the steady quality of technology can be oral.
Specific embodiment following Example has been done detailed description to the present invention:
Prescription 1
Staphylococcus albus 25,000,000,000,000
Escherichia coli 25,000,000,000,000
Ganoderma 110g
Rhizoma Coptidis 110g
More than write out a prescription extracting waste staphylococcus, escherichia coli, after the following drying of 800C, be ground into fine powder respectively, cross 10 mesh sieves, Rhizoma Coptidis and Ganoderma truffle are ground into fine powder, sieve the fine powder mixing, add right amount of auxiliary materials, make granule, add Staphylococcus albus, escherichia coli fine powder mixing, be pressed into 1000, sugar coating or film-coat.
Prescription 2
Staphylococcus albus 15,000,000,000,000
Escherichia coli 15,000,000,000,000
Ganoderma 200g
Rhizoma Coptidis 200g
According to last method, be pressed into 1000, sugar coating or film-coat.
Prescription 3
Staphylococcus albus 75,000 hundred million
Escherichia coli 75,000 hundred million
Ganoderma 130g
Rhizoma Coptidis 130g
According to last method, be pressed into 1000, sugar coating or film-coat.
Prescription 4
Staphylococcus albus 30,000,000,000,000
Escherichia coli 30,000,000,000,000
Ganoderma 100g
Rhizoma Coptidis 100g
According to last method, be pressed into 1000, sugar coating or film-coat.
Prescription 5
Escherichia coli 50,000,000,000,000
Ganoderma 110g
Rhizoma Coptidis 110g
More than prescription is got escherichia coli, after the following drying of 800C, is ground into fine powder, crosses 10 mesh sieves.
Rhizoma Coptidis and Ganoderma truffle are ground into fine powder, sieve, and the fine powder mixing adds right amount of auxiliary materials, makes granule, add escherichia coli fine powder mixing, are pressed into 1000, sugar coating or film-coat.
Prescription 6
Staphylococcus albus 50,000,000,000,000
Ganoderma 110g
Rhizoma Coptidis 110g
More than write out a prescription, the extracting waste staphylococcus after the following drying of 800C, is ground into fine powder, crosses 10 mesh sieves, Rhizoma Coptidis and Ganoderma truffle are ground into fine powder, sieve, and the fine powder mixing adds right amount of auxiliary materials, makes granule, add the Staphylococcus albus fine powder, mixing is pressed into 1000, sugar coating or film-coat.
In the example of above prescription, its active component comprises Staphylococcus albus, escherichia coli, Rhizoma Coptidis, Ganoderma, and said composition comprises as the component of the active component arbitrary composition according to the pharmaceutically acceptable different proportion of above-mentioned form.
Said composition can be by Orally administered, and its each thalline effective dose is respectively hundred million/Kg body weight every day 0.25 hundred million-2500, and preferred dose is respectively every day 2.5 hundred million-25,000,000,000/Kg body weight.
1 be that example is narrated its manufacture method now to write out a prescription.
Prescription
Per thousand consumptions of every consumption of supplementary material
Staphylococcus albus 25,000,000,000 250,000 hundred million
Escherichia coli 25,000,000,000 250,000 hundred million
Ganoderma 0,11g 110g
Rhizoma Coptidis 0,11g 110g
1. raw material is handled 1.1 and is got the required Rhizoma Coptidis 110g of recipe quantity, and Ganoderma 110g removes impurity with Rhizoma Coptidis and cleans and the Ganoderma oven dry; Pulverize 1.2 respectively the Rhizoma Coptidis Ganoderma is put in the pulverizer, cross 80 mesh sieves.Escherichia coli, direct mistake 200 mesh sieves of Staphylococcus albus.
2. mix wet granulation 2.1 binding agents: take by weighing appropriate amount of starch, boil into 5% starch slurry with steam; 2.2 system soft material: Rhizoma Coptidis, each 110g of Ganoderma powder of taking by weighing the producer amount put in the trough type mixing machine and stir, and add an amount of starch slurry, continue to stir into even soft material, and check soft material quality makes it to reach hands and pinches agglomeratingly, and the promptly diffusing of strandings is advisable.2.3 the wet grain of system: get above-mentioned soft material and send in the wet-mixed granulation machine and granulate, cross 14 eye mesh screens and make it to become uniform wet granular.2.4 dry: wet granular is sent in the bad formula drying room of hot blast equably, and forced air drying makes dried granule moisture content be controlled at 3-7%.2.5 granulate: dried granules is put in the Fast granulate machine, produce uniform granule by 12 mesh sieves.2.6 total mixing: take by weighing dried granule by the producer amount and put in the mixer, add Staphylococcus albus, escherichia coli powder and the magnesium stearate of producer amount, make it mix homogeneously.
3. tabletting is selected the circular punch die of 8mm, carries out tabletting, every agreement that contracts a film or TV play to an actor or actress 0.3g.
4. coating 4.1 sugar coatings: get plain sheet to produce, with 70% (W/W) syrup bag unlined garment layer, it is air-dry to add Pulvis Talci, again with gelatin, syrup and Pulvis Talci respectively coating become sealing coat, become sub-coat with syrup with Pulvis Talci bag 15-18 layer, become sugarcoating layer with syrup bag 5-8 layer again, then to be added with the sugar of rust red
The slurry bag becomes uvea for about 12 layers, adds an amount of insect wax polishing at last, overall process 10-12 hour; 4.2 bag film-coat: get with series-produced plain sheet, with 5% green Opadry bag chromatograph promptly, overall process 2 hours.Differentiate: differentiate with Gram staining method, should be positive reaction.
The processing technology of other prescription is basic identical with said method.
Claims (4)
1, a kind of compound medicine tablet of biological bacteria powder for treating dyspneic cough, its main component comprise deactivation thalline, Rhizoma Coptidis, Ganoderma composition, and its proportioning is per 1000 and contains deactivation thalline 15,000,000,000,000-60,000,000,000,000, Rhizoma Coptidis 100-200g, Ganoderma 100-200g.
2, want described compound medicine tablet of biological bacteria powder for treating dyspneic cough according to right, it is characterized in that the deactivation thalline is Staphylococcus albus and or escherichia coli.
3, compound medicine tablet of biological bacteria powder for treating dyspneic cough according to claim 1 and 2, the proportioning that it is characterized in that deactivation thalline, Rhizoma Coptidis, Ganoderma are per 1000 and contain inactivated bacteria 25,000,000,000,000-45,000,000,000,000, Rhizoma Coptidis 100-200g, Ganoderma 100-200g.
4, the compound medicine tablet of biological bacteria powder for treating dyspneic cough of claim 1 is used for anti-smelting bronchitis, related prescription component can be used in combination by its pharmaceutically acceptable any different proportion, and its effective dose is that each thalline is respectively every day 2.5 hundred million-25,000,000,000/Kg body weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01133663 CN1416892A (en) | 2001-11-09 | 2001-11-09 | Compound medicine tablet of biological bacteria powder for treating dyspneic cough |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01133663 CN1416892A (en) | 2001-11-09 | 2001-11-09 | Compound medicine tablet of biological bacteria powder for treating dyspneic cough |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1416892A true CN1416892A (en) | 2003-05-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01133663 Pending CN1416892A (en) | 2001-11-09 | 2001-11-09 | Compound medicine tablet of biological bacteria powder for treating dyspneic cough |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405481A (en) * | 2013-08-24 | 2013-11-27 | 江苏神华药业有限公司 | Medicinal composition containing staphylococcus albus and preparation method thereof |
| CN116531410A (en) * | 2023-07-06 | 2023-08-04 | 首都医科大学附属北京友谊医院 | Application of staphylococcus albus in preparation of composition |
-
2001
- 2001-11-09 CN CN 01133663 patent/CN1416892A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405481A (en) * | 2013-08-24 | 2013-11-27 | 江苏神华药业有限公司 | Medicinal composition containing staphylococcus albus and preparation method thereof |
| CN116531410A (en) * | 2023-07-06 | 2023-08-04 | 首都医科大学附属北京友谊医院 | Application of staphylococcus albus in preparation of composition |
| CN116531410B (en) * | 2023-07-06 | 2023-10-03 | 首都医科大学附属北京友谊医院 | Application of staphylococcus albus in preparation of composition |
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| WD01 | Invention patent application deemed withdrawn after publication |