CN1218742C - Medicine for treating acute bacillary dysentery and acute enteritis - Google Patents

Medicine for treating acute bacillary dysentery and acute enteritis Download PDF

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CN1218742C
CN1218742C CNB2003101060637A CN200310106063A CN1218742C CN 1218742 C CN1218742 C CN 1218742C CN B2003101060637 A CNB2003101060637 A CN B2003101060637A CN 200310106063 A CN200310106063 A CN 200310106063A CN 1218742 C CN1218742 C CN 1218742C
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CN1528417A (en
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李友良
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The present invention provides a medicine for treating acute bacillary dysentery and acute enteritis, which has the advantages of high efficiency, little toxic and side effect, and low price. The medicine for treating acute bacillary dysentery and acute enteritis is prepared from the main drugs of the proportion by weight: 5 to 9 portions of humifuse euphorbia herb and 3 to 6 portions of european verbena. As the improvement, baical skullcap root can be used as supplementary drug, or flaccid knotweed herb is used as the auxiliary drug. The medicine for treating acute bacillary dysentery and acute enteritis can be prepared into any normal oral preparation by using the normal method for Chinese drug preparations. The clinical practice proves that The medicine for treating acute bacillary dysentery and acute enteritis can be used for treating diseases, such as digestive system infection, urinary infection, bleeding, etc., with high therapeutic effect, short treatment course and low price; in addition, the present invention does not have obvious adverse reaction, or toxic and side effect. The present invention has favorable effect for treating bacillary dysentery, acute enteritis, urinary tract infection, bleeding, etc.

Description

A kind of medicine for the treatment of acute bacillary dysentery and acute enteritis
Technical field
The present invention relates to a kind of medicine for the treatment of acute bacillary dysentery and acute enteritis, belong to the field of Chinese medicines.
Background technology
The infection of digestion system and urinary system, hemorrhage be clinical common and multiple disease, treat untimely or thorough Chang Yi and transfer to chronicly, bring difficulty to clinical treatment, cause suffering to the patient.The medicine for the treatment of this type of disease is many, but also has some problems, as: the curative effect that has is not satisfactory, and the toxic and side effects that has is bigger, and what have easily causes drug resistance, and the then price that has is costliness etc. comparatively; The antibiotic preparation that derives from the plant class of this type of disease of treatment has many kinds such as berberine, punching company, garlicin at present, and cmm of simple prescription and compound preparation are also many, uses Herba Portulacae if any list; List is used Herba Euphorbiae Humifusae; Mostly be compound preparation greatly as Herba Portulacae+Herba Euphorbiae Humifusae; Herba Euphorbiae Humifusae+Herba Plantaginis+Herba polygoni hydropiperis+Radix Aristolochiae; Herba Euphorbiae Humifusae+Radix Pulsatillae; Radix Sanguisorbae+Cortex Fraxini+Herba Euphorbiae Humifusae+Radix Scutellariae or the like, but its curative effect is not very good.
Summary of the invention
The technical problem to be solved in the present invention is that the curative effect toxic and side effects undesirable, that have that has of the medicine of existing treatment acute bacillary dysentery and acute enteritis is big, the then price that easily causes drug resistance, has that has problem such as costliness comparatively, provides a kind of this type of disease for the treatment of not only efficient but also toxic and side effects is little and cheap, the medicine source abundant, the medicine of taking convenience.
Choice of drug Herba Euphorbiae Humifusae of the present invention and Herba Verbenae are principal agent.Herba Euphorbiae Humifusae, heat-clearing and toxic substances removing, cooling blood for hemostasis, to control damp-heat dysentery, hematuria, dysurea due to the just down red white or damp invasion of lower energizer, modern pharmacological research confirms that multiple pathogenic coccus and bacillus are had significantly antibacterial, bactericidal action.Modern pharmacological research confirms that multiple pathogenic coccus (as staphylococcus aureus, streptococcus pneumoniae, Streptococcus viridans) and bacillus (as dysentery bacterium, escherichia coli, Bacillus proteus) are had significantly antibacterial, bactericidal action.Herba Verbenae, cold can heat clearing away, bitter can drop-down, function, heat-clearing and toxic substances removing, cool the blood dissipate blood stasis, promoting diuresis to eliminate damp pathogen, can control under the diarrhea due to damp-heat red white, the urine leaching pain.That pharmacological research has is antibiotic, the merit of antiinflammatory, hemostasis and Herba Euphorbiae Humifusae are share then and can strengthen clearing away heat-damp and promoting diuresis, the power of removing heat from blood, hemostasis.
Medicine of the present invention is bright herb as if Herba Euphorbiae Humifusae, Herba Verbenae, and its proportioning (weight ratio) can be Herba Euphorbiae Humifusae 5-7 part, Herba Verbenae 3-6 part, 5 parts of optimum ratio Herba Euphorbiae Humifusaes, 5 parts of Herba Verbenae; If Herba Euphorbiae Humifusae, Herba Verbenae are dried herb, its proportioning (weight ratio) can be Herba Euphorbiae Humifusae 5-9 part, Herba Verbenae 3-6 part, 6 parts of optimum ratio Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae.
As the improvement to this medicine, can select Radix Scutellariae for use is adjuvant drug.Radix Scutellariae, bitter in the mouth, cold in nature, heat clearing away is dry strong, eliminating fire and detoxication, cooling blood for hemostasis, cold and cool and clear and upright, cure mainly jaundice due to damp-heat, intestinal is warded off and is let out dysentery, and pharmacological research it have antibacterial or bactericidal action to multiple coccus and bacillus.Assistant more can strengthen heat-clearing and toxic substances removing with Herba Euphorbiae Humifusae, Herba Verbenae, the effect of cooling blood for hemostasis.So it is better that damp-heat syndrome such as three medicine therapeutic alliance dysentery, acute enteritis and urinary system infection are imitated.
When selecting Radix Scutellariae for use, its proportioning of medicine of the present invention (weight ratio) can be Herba Euphorbiae Humifusae 5-9 part, Herba Verbenae 3-6 part, Radix Scutellariae 3-6 part, 7 parts of optimum ratio Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae, 4 parts of Radix Scutellariaes.
Improve as the another kind to this medicine, can select Herba polygoni hydropiperis for use is accessory drugs.Herba polygoni hydropiperis can reducing swelling and alleviating pain, specially control abscess, dysentery stomachache etc., thus add this accessory drugs can strengthen to digesting be, antibiotic, the antiinflammation of urinary system infection.During use, Herba polygoni hydropiperis can cooperate with Herba Euphorbiae Humifusae, Herba Verbenae, also can cooperate with Herba Euphorbiae Humifusae, Herba Verbenae, Radix Scutellariae.
When selecting Herba polygoni hydropiperis for use, drug ratio of the present invention for (weight ratio) can be: Herba Euphorbiae Humifusae 5-9 part, Herba Verbenae 3-6 part, Radix Scutellariae 3-6 part, Herba polygoni hydropiperis 3-6 part, 7 parts of optimum ratio Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae, 4 parts of Radix Scutellariaes, 4 parts of Herba polygoni hydropiperiss; Perhaps Herba Euphorbiae Humifusae 5-9 part, Herba Verbenae 3-6 part, Herba polygoni hydropiperis 1-4 part, 6 parts of optimum ratio Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae, 2 parts of Herba polygoni hydropiperiss.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral formulations, as these mixed raw materials being become decoct, also decoct can be concentrated and adds the appropriate amount adjuvant, makes granule, tablet or capsule etc. on request.Preferably the active component preparation method of medicine of the present invention may further comprise the steps:
A) take by weighing each crude drug, standby;
B) each the crude drug mixing and water adding with described weight ratio decocts twice, and each amount of water need not have powder, merges decocting liquid twice;
C) decocting liquid after will merging is condensed into the thick paste shape, and dry back grinds the active component of this medicine promptly
Confirm that through clinical practice Drug therapy digestion of the present invention system, urinary system infection, disease such as hemorrhage be curative effect height, short treating period, inexpensive not only, and does not have tangible untoward reaction and toxic and side effects.Especially treat bacillary dysentery, acute enteritis, urinary tract infection, effect such as hemorrhage is excellent.
The specific embodiment
Further set forth the contents such as preparation, preparation, consumption, usage and clinical efficacy of medicine of the present invention below again.
[embodiment 1]
1, clinical data
1.1 physical data diagnosis and treatment outpatient is totally 622 examples, acute bacillary dysentery 126 examples wherein, acute enteritis 496 examples, be divided into test group (T group) and matched group (C group) at random, two groups of case load equalizations are every group acute bacillary dysentery 63 examples, acute enteritis 248 examples, 5 years old of age minimum, maximum 81 years old, the men and women had concurrently.
1.2 diagnostic criteria
1.2.1 acute bacillary dysentery diagnostic criteria morbidity is anxious, and heating, stomachache, diarrhoea (it is inferior to tens of times surplus in the of 10 to defecate every day), tenesmus are arranged, pus and blood Mucous Stool etc., and left lower quadrant has tenderness; The excrement microscopy has a large amount of pus cells and leukocyte, the dispersive erythrocyte in the full visual field, and phagocyte is arranged; Excrement incubation growth dysentery bacterium.
1.2.2 acute enteritis diagnostic criteria stomachache, the rare water sample of diarrhoea or Mucous Stool, excrement microscopy pus cell (15~30 in each high power lens visual field is+, 30~50 are ++, the plain cloth visual field is +++), as seen erythrocyte is arranged.
1.3 curative effect judging standard
Recovery from illness: clinical symptoms and sign all disappear, and every day, times of defecation was no more than 2 times, and outward appearance is normal, excrement microscopy next day of after the drug withdrawal (bacillary dysentery patient does the feces dysentery bacterium and cultivates), and double feminine gender is followed up a case by regular visits to and is not seen recurrence half a year.
Effectively: clinical symptoms and body card takes a turn for the better to some extent behind the medicine, but eliminates fully, every day times of defecation still more than 2 times, the excrement inspection is negative or positive;
Invalid; Symptom, sign do not have improvement, and every day, times of defecation was examined still positive 2 times to apply manure to the fields.
1.4 the preparation of medicine, consumption and usage
T group: every day 2 oral decocts of making as follows:
A) take by weighing Herba Euphorbiae Humifusae, each each 50g (some herb consumptions are respectively 15g and 10g at every turn) of the bright herb of Herba Verbenae two medicines at every turn;
B) described Herba Euphorbiae Humifusae, Herba Verbenae two flavor medicines are decocted with water, the gained decocting liquid is a kind of peroral dosage form of this medicine
The C group: use Berberine Tablet, each 0.3 gram, every day 3 times, oral;
2, result
2.1 curative effect can be found out from table 1:
(1) for acute bacillary dysentery: T group recovery from illness 62 examples (98.4%), effective 1 example (1.6%), effective percentage 100%; C group recovery from illness 54 examples (85.7%), effective 5 examples (7.9%), effective percentage 93.7%, invalid 4 examples, wherein 2 examples are to use the invalid case of other drug before the treatment, there have 1 example to transfer in this 2 example to be chronic.
(2) for acute enteritis: T group 248 examples are all cured; C group recovery from illness 299 examples (92.3%), effective 14 examples (5.6%), effective percentage 98%; Invalid 2 examples (2.0%).
Group Recovery from illness Effectively Invalid Cure rate (%) P Effective percentage (%) P Inefficiency (%) P
Bacillary dysentery T 62 1 98.4 0.0168 100 0.119 0.119
C 54 5 4 85.7 93.7 6.3 0.612
Acute enteritis T 248 100 <0.0001 0.612
C 229 14 5 92.3 98.0
Table 1
2.2 from table 2, can find out the course of treatment:
(1) for acute bacillary dysentery: the T group was all cured in 5 days; C group except that 5 examples effectively, 4 examples invalid, all the other cases were all cured in 8 days; There have 1 example to transfer in invalid 4 examples to be chronic.
(2) for acute enteritis: the T group was all cured in 3 days; The C group is removed effective 14 examples, invalid 5 exceptions, and all the other cases were all cured in 6 days.
Group Time (d) U
1 2 3 4 5 6 7 8
Bacillary dysentery T 12 19 31 2.5483 P=0.0108 3
C 7 14 18 10 4 2
Acute enteritis T 38 126 84 7.2922 p=0.0000
C 12 76 102 22 11 6
Table 2
2.3 take place to feel sick and epigastric discomfort after untoward reaction and toxic and side effects test group patient except that feeling flavour of a drug than the hardship, have 2 patients to take medicine; Matched group has 5 routine patients to occur feeling sick and epigastric discomfort; T group and C group are not all found other untoward reaction and toxic and side effects in therapeutic process.
[embodiment 2]
1, clinical data
1.1 physical data diagnosis and treatment outpatient is totally 252 examples, acute bacillary dysentery 98 examples wherein, and acute enteritis 154 examples are divided into test group (T group) and matched group (C group) at random, two groups of case load equalizations, 8 years old of age minimum, maximum 76 years old, the men and women had concurrently.
1.2 diagnostic criteria and curative effect judging standard are with embodiment 1
1.3 the preparation of medicine, consumption and usage
Test group (T group): get dried Herba Euphorbiae Humifusae 18g, dried Herba Verbenae 6g at every turn respectively, make decoct, every day 2 times is oral
Matched group (C group): use Berberine Tablet, each 0.3 gram, every day 3 times, oral
2, result
2.1 curative effect (1) acute bacillary dysentery: T group recovery from illness 47 examples (95.9%), effective 2 examples (4.0%), effective percentage 100%; C group recovery from illness 43 examples (87.8%), effective 4 examples (8.2%), effective percentage 95.9%, invalid 2 examples (4.0%).
(2) acute enteritis: T group recovery from illness 76 examples (98.7%), effective 1 example (1.3%), effective percentage 100%; C group recovery from illness 72 examples (93.5%), effective 4 examples (5.2%), effective percentage 98.7%; Invalid 1 example (1.3%).
2.2 the course of treatment, (1) acute bacillary dysentery: T organized except that 2 routine responders, all the other 47 examples were all cured in 6 days; C group except that 4 examples effectively, 2 examples invalid, all the other cases were all cured in 8 days.
(2) acute enteritis: T group is except that 1 example is effective, and all the other cases were all cured in 3 days; The C group is removed effective 4 examples, invalid 1 exception, and all the other cases were all cured in 6 days.
2.3 untoward reaction and toxic and side effects test group have 1 example to occur feeling sick and epigastric discomfort; Matched group has 2 examples to occur feeling sick and epigastric discomfort; In addition, two groups are not all had other untoward reaction and toxic and side effects.
[embodiment 3]
1, clinical data
1.1 physical data diagnosis and treatment outpatient service acute enteritis patient is totally 424 examples, is divided into test group (T group) and contrast (C group) two groups of case load equalizations at random, at minimum 18 years old of age, maximum 79 years old, the men and women had concurrently.
1.2 diagnostic criteria and curative effect judging standard are with embodiment 1
1.3 the preparation of medicine, consumption and usage
T group: each 15 grams, every day 3 oral these medicines of making as follows granule:
A) weighting raw materials Herba Euphorbiae Humifusae 150kg, Herba Verbenae 100kg and the dried herb of Herba polygoni hydropiperis 50kg are standby;
B) each crude drug mixing and water adding is decocted twice, decocted 2 hours at every turn, amount of water need not have powder (water exceeds how many height of powder, and it is different and different to look container), merges decocting liquid twice;
C) the decocting liquid concentrating under reduced pressure after will merging becomes the thick paste shape, adds appropriate amount of auxiliary materials (sugar, dextrin etc.) again and mixes thoroughly and make granule, is dried into granule, packing.
C group: use the fluoroquinolones medicine--each 0.2 gram of-norfloxacin (FUPAISUAN JIAONANG), every day 3 times, oral;
2, result
2.1 curative effect can be found out from table 3:
T group 212 examples are all cured, and cure rate reaches 100%; The C group is cured 197 examples (92.9%), effective 10 examples, total effective rate 97.6%, invalid 5 examples (2.4%)
Group Recovery from illness Effectively Invalid Cure rate (%) P Effective percentage (%) P Inefficiency (%)
T 212 100.0 0.0000 0.0610
C 197 10 5 92.9 97.6 2.4
Table 3
2.2 from table 4, can find out the course of treatment:
The T group was all cured in 3 days, and the C group was cured 173 examples (81.6%) in 3 days, cured 197 examples (92.9%) altogether, and the course of treatment is the longest at 6 days, effective 10 examples, invalid 5 examples
2.3 untoward reaction and toxic and side effects T group have 4 examples to occur feeling sick and epigastric discomfort; The C group has 8 examples to occur feeling sick and epigastric discomfort, and 2 routine GPT slightly raise, and all blood leukocytes of 1 exception reduce, and skin appears in 1 example examines, and all recovers normal after the above situation drug withdrawal.
Group Time/d U
1 2 3 4 5 6
T 72 115 25 7.3574
C 31 78 64 14 7 3 0.0000
Table 4
[embodiment 4]
1, clinical data
1.1 physical data diagnosis and treatment outpatient service acute enteritis patient is totally 204 examples, is divided into test group (T group) and two groups of case load equalizations of matched group (C group) at random, at minimum 18 years old of age, maximum 76 years old, the men and women had concurrently.
1.2 diagnostic criteria and curative effect judging standard are with embodiment 1
1.3 the preparation of medicine, consumption and usage
T group: each 15 grams, every day 3 oral these medicines of making as follows granule:
Get the dried herb 160kg of Herba Euphorbiae Humifusae, Herba Verbenae and Herba polygoni hydropiperis three medicines, 60kg, 20kg respectively, other preparation process together
Embodiment 3.
C group: use the fluoroquinolones medicine--each 0.2 gram of-norfloxacin (FUPAISUAN JIAONANG), every day 3 times, oral;
2, result
2.1 curative effect T group 100 examples are all cured (98.0%), effective 2 examples (2.0%), effective percentage 100%; The C group is cured 94 examples (92.2%), effective 5 examples (4.9%), effective percentage 97.1%, invalid 3 examples (2.9%)
2.2 the course of treatment, T organized except that 2 routine responders, all the other cases were all cured in 3 days, and it is effective that the C group is removed 5 examples, and outside 3 examples were invalid, all the other 94 examples (92.2%) were all cured, and be 6 days the course of treatment the longest.
2.3 untoward reaction and toxic and side effects T group have 1 example to occur feeling sick, 1 example sensation epigastric discomfort; The C group has 2 examples to occur feeling sick, 1 example sensation epigastric discomfort, and skin appears in 1 example examines, and in addition, two groups of cases all do not have other untoward reaction.。
[embodiment 5]
1, clinical data
1.1 physical data diagnosis and treatment outpatient is totally 412 examples, acute bacillary dysentery 104 examples wherein, and acute enteritis 308 examples are divided into test group (T group) and matched group (C group) at random, two groups of case load equalizations, 8 years old of age minimum, maximum 78 years old, the men and women had concurrently.
1.2 diagnostic criteria and curative effect judging standard are with embodiment 1
1.3 the preparation consumption and the usage of medicine
T group: get Herba Euphorbiae Humifusae, Herba Verbenae, Radix Scutellariae three medicines (the former two is dried herb, and the latter be dried scutellariae,radix) 140kg, 80kg, 80kg respectively, other preparation process is made granule with embodiment 3,15g at every turn, and every day 3 times is oral;
The C group: use Berberine Tablet, each 0.3 gram, every day 3 times, oral;
2, result
2.1 curative effect (1) acute bacillary dysentery: T group recovery from illness 52 examples are all cured (100%); C group recovery from illness 45 examples (86.5%), effective 4 examples (7.7%), effective percentage 94.2%, invalid 3 examples (5.8%).
(2) acute enteritis: T group 154 examples are all cured (100%); C group recovery from illness 144 examples (93.5%), effective 7 examples (4.5%), invalid 3 examples (1.9%).
2.2 the course of treatment, (1) acute bacillary dysentery: T all cured in organizing 5 days; C group except that 4 examples effectively, 3 examples invalid, all the other cases are all cured; The longest 8 days of the course of treatment.
(2) acute enteritis: T group was all cured (100%) in 3 days; The C group is removed effective 7 examples, and outside 3 examples were invalid, all the other 144 examples were all cured, and be 6 days the course of treatment the longest.
2.3 untoward reaction and toxic and side effects T group patient except that feeling flavour of a drug than the hardship, have 4 patients to occur feeling sick and epigastric discomfort; C organizes 3 people and feels to go up degree portion discomfort; T group and C group patient all do not find other untoward reaction and toxic and side effects.
[embodiment 6]
1, clinical data
1.1 physical data diagnosis and treatment outpatient is totally 332 examples, acute bacillary dysentery 96 examples wherein, and acute enteritis 236 examples are divided into test group (T group) and matched group (C group) at random, two groups of case load equalizations, 9 years old of age minimum, maximum 77 years old, the men and women had concurrently.
1.2 diagnostic criteria and curative effect judging standard are with embodiment 1
1.3 the preparation consumption and the usage of medicine
T group: get Herba Euphorbiae Humifusae, Herba Verbenae, Radix Scutellariae three medicines (the former two is dried herb, and the latter be dried scutellariae,radix) 100kg, 120kg, 100kg respectively, other preparation process is made granule with embodiment 3,15g at every turn, and every day 3 times is oral;
The C group: use Berberine Tablet, each 0.3 gram, every day 3 times, oral;
2, result
2.1 curative effect (1) acute bacillary dysentery: T group recovery from illness 47 examples are all cured (97.9%), effective 1 example (2.1%), effective percentage (100%); C group recovery from illness 41 examples (85.4%), effective 4 examples (8.3%), invalid 3 examples (6.3%).
(2) acute enteritis: T group 116 examples are all cured (98.3%), effective 2 examples (1.7%), effective percentage 100%; C group recovery from illness 108 examples (91.5%), effective 7 examples (5.9%), effective percentage 97.4%, invalid 3 examples (2.5%).
2.2 the course of treatment, (1) acute bacillary dysentery: T organized except that 1 routine responder, all the other 47 examples were all cured in 6 days; C group except that 4 examples effectively, 3 examples invalid, all the other 41 examples were all cured in 8 days.
(2) acute enteritis: T group is except that 2 examples are effective, and all the other 116 examples were all cured in 3 days; The C group is removed 7 examples effectively, and outside 3 examples were invalid, all the other 108 examples were cured in 6 days.
2.3 untoward reaction and toxic and side effects T group patient except that feeling flavour of a drug than the hardship, have 3 examples to occur feeling sick and epigastric discomfort; The C group also has 3 examples to occur feeling sick and epigastric discomfort; T group and C group patient all do not find other untoward reaction and toxic and side effects.
[embodiment 7]
1, clinical data
1.1 physical data diagnosis and treatment outpatient service acute enteritis patient is totally 192 examples, is divided into test group (T group) and two groups of case load equalizations of matched group (C group) at random, at minimum 9 years old of age, maximum 79 years old, the men and women had concurrently.
1.2 diagnostic criteria and curative effect judging standard are with embodiment 1
1.3 the preparation of medicine, consumption and usage
The C group: use Berberine Tablet, each 0.3 gram, every day 3 times, oral;
T group: get dried Herba Euphorbiae Humifusae, Herba Verbenae, Radix Scutellariae and Herba polygoni hydropiperis four medicine 140kg, 80kg, 80kg, 80kg respectively, other preparation process is made granule with embodiment 3, each 15g, and every day 3 times is oral;
2, result
2.1 curative effect T group 96 examples are all cured, and due to case medication after 2 days, it is normal that times of defecation all recovers; The C group is cured 90 examples (93.8%), effective 4 examples (4.2%), invalid 2 examples (2.1%).
2.2 the course of treatment: T organizes in all cases 3 days and all cures; The C group is removed 4 examples effectively, and outside 2 examples were invalid, all the other 90 examples were all cured.The course of treatment is the longest to be 6 days.
2.3 untoward reaction and toxic and side effects T group patient except that feeling flavour of a drug than the hardship, have 3 examples to occur feeling sick and epigastric discomfort, 1 example appearance vomiting; The C group has 3 example sensation epigastric discomforts, and 2 groups are not all had other untoward reaction.

Claims (8)

1, a kind of medicine for the treatment of acute bacillary dysentery and acute enteritis is characterized in that it is made by crude drug Herba Euphorbiae Humifusae, Herba Verbenae, and the weight proportion of described crude drug is: Herba Euphorbiae Humifusae 5-9 part, Herba Verbenae 3-6 part.
2, medicine according to claim 1 is characterized in that: wherein the consumption of each crude drug is 6 parts of Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae.
3, medicine according to claim 1 is characterized in that: also add Radix Scutellariae 3-6 part in the described crude drug.
4, medicine according to claim 3 is characterized in that: wherein the consumption of each crude drug is 7 parts of Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae, 4 parts of Radix Scutellariaes.
5, medicine according to claim 1 is characterized in that: also add Herba polygoni hydropiperis 1-4 part in the described crude drug.
6, medicine according to claim 5 is characterized in that: wherein the consumption of each crude drug is 6 parts of Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae, 2 parts of Herba polygoni hydropiperiss.
7, medicine according to claim 3 is characterized in that: also add Herba polygoni hydropiperis 3-6 part in the described crude drug.
8, medicine according to claim 7 is characterized in that: wherein the consumption of each crude drug is 7 parts of Herba Euphorbiae Humifusaes, 4 parts of Herba Verbenae, 4 parts of Radix Scutellariaes, 4 parts of Herba polygoni hydropiperiss.
CNB2003101060637A 2003-10-21 2003-10-21 Medicine for treating acute bacillary dysentery and acute enteritis Expired - Fee Related CN1218742C (en)

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CN101904923A (en) * 2010-07-29 2010-12-08 陈德顺 Oral traditional Chinese medicine for treating bacillary dysentery
CN104000969B (en) * 2014-05-16 2018-12-04 青岛大学医学院附属医院 A kind of Chinese materia medica preparation for treating children's intestines system lymphonodi abdominales inflammation

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