CN1748771A - Chinese medicine composition for treating diabetes and its preparing method and use - Google Patents

Chinese medicine composition for treating diabetes and its preparing method and use Download PDF

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Publication number
CN1748771A
CN1748771A CN 200510109039 CN200510109039A CN1748771A CN 1748771 A CN1748771 A CN 1748771A CN 200510109039 CN200510109039 CN 200510109039 CN 200510109039 A CN200510109039 A CN 200510109039A CN 1748771 A CN1748771 A CN 1748771A
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China
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chinese medicine
pharmaceutical composition
treatment
diabetes
ganoderma
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CN 200510109039
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CN100556440C (en
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李玉平
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Individual
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Abstract

The Chinese medicine composition for treating diabetes is prepared with corn stigma, glossy ganoderma, balsam pear and licorice in certain weight proportion, and through mixing in water, crushing, heating at 70-90 deg c for 2-5 hr, filtering, concentrating and other steps. The present invention has high curative effect, short treating period, low cost, easy use and no toxic side effect.

Description

A kind of Chinese medicine pharmaceutical composition for the treatment of diabetes and its production and application
Technical field
The present invention relates to a kind of Chinese medicine pharmaceutical composition for the treatment of diabetes and its production and application.
Background technology
The medicine of treatment diabetes mainly be that the insulin type product has good therapeutical effect to the patient, but its side effect is apparent in view at present, and is also many to patient's dietary restrictions.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine pharmaceutical composition for the treatment of diabetes and its production and application, overcome the shortcoming of said medicine.
The objective of the invention is to be achieved through the following technical solutions:
A kind of pharmaceutical composition for the treatment of diabetes provided by the invention is by the preparation that comprises that following raw material components is prepared from: Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae;
Described raw material components is preferably following parts by weight of component: Stigma Maydis 20-60, Ganoderma 20-40, Fructus Momordicae charantiae 10-30, Radix Glycyrrhizae 4-10.
The best following parts by weight of component of described raw material components: Stigma Maydis 40, Ganoderma 30, Fructus Momordicae charantiae 20, Radix Glycyrrhizae 6.
Described pharmaceutical composition can be made any oral medicine pharmaceutically, as tablet, capsule, oral liquid, unguentum, is preferably oral liquid.
The present invention also provides a kind of Chinese medicine preparation of drug combination method for the treatment of diabetes, may further comprise the steps:
(1) above-mentioned Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae are added suitable quantity of water and mix pulverizing;
(2) said mixture places the container internal heating to 70-90 ℃ of stirring 2-5 hour;
(3) said mixture filters, and is concentrated into proportion 1-1.1, and packing promptly gets the pharmaceutical composition for the treatment of diabetes.
The mixing of described step (1), be that 260,40,30,20,6 or 260,60,30,20,10 proportioning is pulverized and is placed on the open-top receptacle internal heating and stirred 2-5 hour at interval to 70-90 ℃ temperature preferably, make in the weight portion ratio of water, Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae.
The thermal response of described step (2) is under 85 ℃, 30 minutes at interval, stirred 15 minutes, and reacted 4 hours; Described step (3) mixture filters, and is concentrated into proportion 1-1.1, is distributed into oral liquid, as makes the oral liquid of 20ml.
The present invention also provides the application of described Chinese medicine pharmaceutical composition in preparation treatment diabetes medicament method, and this pharmaceutical composition also comprises pharmaceutically available pharmaceutical necessities.
Stigma Maydis in the medicine of the present invention: blood sugar lowering and diuresis especially have good diuresis to urine urgency-frequency; Ganoderma has comprehensive human body immunity improving power; Fructus Momordicae charantiae, Radix Glycyrrhizae have hypoglycemic effect.
Medicine of the present invention has the following advantages:
1, medicine of the present invention, adopting the botanical herbs material is raw material, and utilizing the method for elevated temperature heat lixiviate, the oral medicine of making has unique curative effect to the treatment diabetes, treating both the principal and secondary aspects of a disease, the present invention has no side effect to the patient, have evident in efficacy, short treating period, instant effect, expense is low, be easy to the characteristics that absorb and use.
2, take medicine of the present invention, obviously reduced with interior blood glucose in 7 days, the improvement of patient's mental status, edema, weak doing well,improving or disappearance, treat one to two course of treatment, blood glucose can reach normal value gradually, can treat diabetes effectively, recover patient's pancreas splenic function, through over 2 years to the clinical practice of 300 routine diabeticss, obtained curative effect preferably, its cure rate reaches more than 80%.
3, during this pharmaceutical composition, the patient can not aviod certain food as normal person's diet, is the characteristics of pharmaceutical composition of the present invention.
For proving above-mentioned advantage, the embodiment of the invention 1 pharmaceutical composition has carried out following clinical treatment, and relevant treatment situation is as follows:
1, patient: select medical history, the state of an illness.
2, patient source: hospital outpatient.
3, go into the group standard: the sex age is not limit, and medical history is arranged.
4, instructions of taking: oral liquid, the patient is oral, every day secondary, each one, 20ml/ props up, 30 days is a course of treatment.
5, efficacy evaluation:
Cure: blood glucose is low, the healing of edema, weak, postoperative or wound, after taking one to two course of treatment, and doing well,improving or disappearance.
Produce effects: blood glucose is low, the healing of edema, weak, postoperative or wound, and after taking one to two course of treatment, symptom is obviously improved or disappeared.
Effectively: blood glucose is low, the healing of edema, weak, postoperative or wound, and after taking one to two course of treatment, symptom has to be improved or disappear.
Invalid: blood glucose is low, the healing of edema, weak, postoperative or wound, and after taking one to two course of treatment, symptom is not improved.
6, case:
(1) sex: be pressed into the group standard, treat diabetes 300 people altogether, women 200 people, male 100 people.
(2) 80 examples in the course of disease: the 1-3,120 examples of 3-6,100 examples more than 7 years.
(3) age group: 40 years old-50 years old 120 examples, 51-60 year 80 examples, 100 examples more than 61 years old.
7, therapeutic outcome: cure 246 people, cure rate 82.0%; Produce effects 276 people, obvious effective rate 92%; Effective 100 people, effective percentage 100%; Invalid 0 people, inefficiency 0%.
By evidence, pharmaceutical composition of the present invention can play good effect to the recovery of patient's insulin, the treatment diabetes have significant curative effect, and the patient is had no side effect, and effective percentage reaches more than 80%, takes one to two course of treatment, doing well,improving or disappearances such as patient's blood glucose, weak, edema, the mental status is greatly improved, and diabetic symptom disappears, and reaches the purpose of treatment.Take especially during this pharmaceutical composition, the patient can not aviod certain food as normal person's diet, is the characteristics of pharmaceutical composition of the present invention.
The specific embodiment
Embodiment 1: oral liquid
A kind of pharmaceutical composition for the treatment of diabetes, (kg) is prepared from by following raw material components: Stigma Maydis 40, Ganoderma 30, Fructus Momordicae charantiae 20, Radix Glycyrrhizae 6.
Preparation method:
(1) above-mentioned Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae are added 260L water and mix pulverizing;
(2) said mixture places in the container, is heated to 70-90 ℃, stirs 15 minutes in 30 minutes at interval, stirs 4 hours;
(3) said mixture filters, and is concentrated into proportion 1-1.1, carries out canned 20ml, sterilization, promptly.
Embodiment 2: oral liquid
A kind of pharmaceutical composition for the treatment of diabetes, (kg) is prepared from by following raw material components: Stigma Maydis 20, Ganoderma 20, Fructus Momordicae charantiae 10, Radix Glycyrrhizae 4.
Preparation method:
(1) above-mentioned Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae are added 200L water and mix pulverizing;
(2) said mixture places in the container, is heated to 85 ℃, stirs thermal response 3 hours at interval; Stirred 3-5 hour;
(3) said mixture filters, and is concentrated into proportion 1-1.1, carry out canned, sterilization, promptly.
Embodiment 3: capsule
A kind of pharmaceutical composition for the treatment of diabetes, (kg) is prepared from by following raw material components: Stigma Maydis 50, Ganoderma 40, Fructus Momordicae charantiae 30, Radix Glycyrrhizae 10.
Preparation method:
(1) above-mentioned Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae are added 300L water and mix pulverizing;
(2) said mixture places in the container, is heated to 70 ℃, stirs thermal response 5 hours at interval; Stirred 3-5 hour;
(3) said mixture filters, and concentrates, and drying is pulverized, and is encapsulated, sterilization, promptly.
Embodiment 4: tablet
A kind of pharmaceutical composition for the treatment of diabetes, (kg) is prepared from by following raw material components: Stigma Maydis 30, Ganoderma 40, Fructus Momordicae charantiae 30, Radix Glycyrrhizae 50.
Preparation method:
(1) above-mentioned Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae are added suitable quantity of water and mix pulverizing;
(2) said mixture places in the container, is heated to 90 ℃, stirs thermal response 4 hours at interval; Stirred 4 hours;
(3) said mixture filters, and concentrates, and drying is pulverized, and mixes the 0.5kg magnesium stearate, tabletting, and sterilization, promptly.
Embodiment 5: oral liquid/unguentum
A kind of pharmaceutical composition for the treatment of diabetes, (kg) is prepared from by following raw material components: Stigma Maydis 60, Ganoderma 30, Fructus Momordicae charantiae 20, Radix Glycyrrhizae 10.
Preparation method:
(1) above-mentioned Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae are added suitable quantity of water and mix pulverizing;
(2) said mixture places in the container, is heated to 70-90 ℃, stirs 15 minutes in 30 minutes at interval, stirs 2 hours;
(3) said mixture filters, and is concentrated into proportion 1-1.1, carries out canned 20ml, sterilization, promptly.Or the further concentrated unguentum of making.

Claims (8)

1, a kind of Chinese medicine pharmaceutical composition for the treatment of diabetes is by the preparation that comprises that following raw material components is prepared from: Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae.
2, according to the Chinese medicine pharmaceutical composition of the treatment diabetes of claim 1, the following parts by weight of component of described raw material components: Stigma Maydis 20-60, Ganoderma 20-40, Fructus Momordicae charantiae 10-30, Radix Glycyrrhizae 4-10.
3, according to the Chinese medicine pharmaceutical composition of the treatment diabetes of claim 2, the following parts by weight of component of described raw material components: Stigma Maydis 40, Ganoderma 30, Fructus Momordicae charantiae 20, Radix Glycyrrhizae 6.
4, according to the Chinese medicine pharmaceutical composition of the treatment diabetes of right 1,2 or 3, described preparation is oral liquid, capsule, tablet, unguentum.
5, a kind of Chinese medicine preparation of drug combination method for the treatment of diabetes may further comprise the steps:
(1) Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, the Radix Glycyrrhizae with one of claim 1-4 adds suitable quantity of water mixing pulverizing;
(2) said mixture places the container internal heating to 70-90 ℃ of stirring 3-5 hour;
(3) said mixture filters, and concentrates, and preparation method makes the pharmaceutical composition for the treatment of diabetes routinely again.
6, according to the Chinese medicine preparation of drug combination method of the treatment diabetes of claim 5, the mixing of described step (1) is that 260,40,30,20,6 or 260,60,30,20,10 proportioning is pulverized and is placed on the open-top receptacle internal heating and stirred 2-5 hour at interval to 70-90 ℃ temperature in the weight portion ratio of water, Stigma Maydis, Ganoderma, Fructus Momordicae charantiae, Radix Glycyrrhizae, makes.
7, according to the Chinese medicine preparation of drug combination method of the treatment diabetes of claim 5 or 6, the thermal response of described step (2) is under 85 ℃, 30 minutes at interval, stirred 15 minutes, and reacted 4 hours; Described step (3) mixture filters, and is concentrated into proportion 1-1.1, is distributed into oral liquid.
8, the Chinese medicine pharmaceutical composition of one of claim 1-4 is in the application of preparation treatment diabetes medicament method, and this pharmaceutical composition also comprises pharmaceutically available pharmaceutical necessities.
CNB2005101090398A 2005-10-17 2005-10-17 A kind of Chinese medicine pharmaceutical composition for the treatment of diabetes and its production and application Expired - Fee Related CN100556440C (en)

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CNB2005101090398A CN100556440C (en) 2005-10-17 2005-10-17 A kind of Chinese medicine pharmaceutical composition for the treatment of diabetes and its production and application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2005101090398A CN100556440C (en) 2005-10-17 2005-10-17 A kind of Chinese medicine pharmaceutical composition for the treatment of diabetes and its production and application

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CN1748771A true CN1748771A (en) 2006-03-22
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104984102A (en) * 2015-06-19 2015-10-21 青岛浩大海洋保健食品有限公司 Astaxanthin health care capsule with blood sugar decreasing effect
CN106262784A (en) * 2016-08-10 2017-01-04 翔天农业开发集团股份有限公司 A kind of hypoglycemic composition and preparation method thereof
CN108785549A (en) * 2017-05-04 2018-11-13 王丽敏 A kind of Chinese medicine preparation and preparation method for treating diabetes

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104984102A (en) * 2015-06-19 2015-10-21 青岛浩大海洋保健食品有限公司 Astaxanthin health care capsule with blood sugar decreasing effect
CN106262784A (en) * 2016-08-10 2017-01-04 翔天农业开发集团股份有限公司 A kind of hypoglycemic composition and preparation method thereof
CN108785549A (en) * 2017-05-04 2018-11-13 王丽敏 A kind of Chinese medicine preparation and preparation method for treating diabetes

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