CN1839882A - Medicament composition for treating tinea pedis and tinea corporis - Google Patents
Medicament composition for treating tinea pedis and tinea corporis Download PDFInfo
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- CN1839882A CN1839882A CN 200510042600 CN200510042600A CN1839882A CN 1839882 A CN1839882 A CN 1839882A CN 200510042600 CN200510042600 CN 200510042600 CN 200510042600 A CN200510042600 A CN 200510042600A CN 1839882 A CN1839882 A CN 1839882A
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Abstract
The invention discloses a pharmaceutical composition for treating tinea pedis and tinea corporis, which is prepared from the following ingredients (by weight portion): cinnabar 2-4 parts, boneol 5-9 parts, borax 4-9 parts, sulfalene oxazole 4-20 parts, trimethoprim 0.8-4 parts, aspirin 3-18 parts, and korostatin 2-8 parts.
Description
Technical field:
The present invention relates to a kind of medicine for the treatment of skin diseases, specifically a kind of is the pharmaceutical composition that is used for the treatment of tinea pedis and tinea corporis of preparation raw material with the Chinese medicine and western medicine.
Technical background:
Tinea pedis is commonly called as tinea pedis, is a kind of foot's disease that causes of being grown by fungus.Its main disease be between sole, toe, toe etc. the position pruritus, decortication, redness appear, so that phenomenons such as vesicle if bacterial infection is arranged, more symptoms such as inflammation and suppuration may occur.Tinea pedis extensively exists in the area of wet weather, and particularly some areas people of being engaged in operation at sea for a long time or wearing airtight footwear for a long time, or some bathing places under the undemanding situation of sterilization, is easy to cause fungal infection and suffers from tinea pedis.Can cause disease damp and hot dryness-transformation of a specified duration after suffering from tinea pedis, QI and blood is obstructed, and skin loses nutrition, and is coarse dry and cracked, very itches unbearably, not only can cause suffering to me, and be easy to infect to other people.Though it is multiple that the medicine of treatment tinea pedis has, and all have certain effect, and its limitation is separately also arranged.Clinical trial proves, if use western medicine for a long time, then can produce significant side effects, and effect is unsatisfactory; If adopt pure treatment by Chinese herbs, then not only treatment time is long, also is difficult to adhere to.Thereby for a long time, people do not find a kind of medicine and method of treatment tinea pedis that can treating both the principal and secondary aspects of a disease.Tens of kinds of the medicines of prior art treatment tinea pedis and other tinea class disease such as tinea corporis, particularly medicine for external use is a lot of.But the ubiquity DeGrain is cured the symptoms, not the disease, and it is single to treat the disease class, easily recurrence.Some medicine valency is high especially, and general patient is difficult to bear.
Summary of the invention:
It is raw material with the Chinese and western medicine medicine that technical assignment of the present invention provides a kind of, and preparation technology is simple, easy to use, can effectively adjust sole QI and blood balance, kills fungus, reaches the treatment tinea pedis for the treatment of both the principal and secondary aspects of a disease purpose and the pharmaceutical composition of tinea corporis.
The technical solution adopted for the present invention to solve the technical problems is:
It is to be formed by the following materials based on weight proportioning:
Cinnabaris 2-4 part Borneolum Syntheticum 5-9 part Borax 4-9 part
Sulfamethoxazole 4-20 part trimethoprim 0.8-4 part
Aspirin 3-18 part nystatin 2-8 part
The main effect of above-mentioned each material composition is:
Cinnabaris:
Nature and flavor with return through sweet, cold, poisonous, go into heart channel
Function cures mainly: calm the nerves, arresting convulsion makes eye bright, detoxifcation.Control demented, the palpitation with fear, vexed, the insomnia, dizzy, blurred vision, toxic swelling, skin infection, scabies.
Borneolum Syntheticum:
Nature and flavor with return through arduous, the heart, lung meridian are gone in cold
Function cures mainly: logical all keys, and the stagnated fire of loosing, removing nebula makes eye bright, and reducing swelling and alleviating pain is controlled the apoplexy locked mouth, calentura coma ， Jing Epilepsy expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, conjunctivitis, sick in the pinworm.
Borax:
Nature and flavor with return through sweet salty, lung, stomach warp are gone in cold
Function cures mainly: the hot expectorant that disappears, and it is anticorrosion to detoxify, and controls laryngopharynx swelling and pain, aphtha of the mouth and tongue, the conjunctival congestion cataracta, bone is choked, the cancer of the esophagus, cough expectorant is thick.
Sulfamethoxazole:
Another name: sulfamethoxazole, sulfamethoxazole, sulfamethoxazole
Effect and purposes: antimicrobial spectrum is similar to SD, but antibacterial action is stronger.The dissolubility of sulphonamides metabolite acetylate in vivo is low, separates out crystallization easily in urethra and causes crystalluria, hematuria and close urine etc., heavy dose ofly uses appropriate to the occasion and sodium bicarbonate with clothes.TMP share with synergist, and its antibacterial efficacy has obvious enhancing, can increase several times to tens times.Clinical tonsillitis, acute bronchitis, pulmonary infection, urinary tract infection, cutization pyogenic infection, bacillary dysentery and the typhoid fever etc. of being used for.
Trimethoprim:
Another name: trimethoprim (TMP), trimethoprim
Effect and purposes: this medicine is synthetic broad spectrum antimicrobicide, and its antimicrobial spectrum is similar to SMZ, and is effective to most gram positive bacterias and negative bacterium.If use the very easy generation drug resistance of antibacterial separately.Share with sulphonamides, can make the folic acid metabolism of antibacterial be subjected to double blocking, promptly sulphonamides suppresses dihydrofolate synthetase, suppresses the synthetic of dihydrofoilic acid; And TMP suppresses dihydrofolate reductase, makes dihydrofoilic acid can not be reduced to tetrahydrofolic acid and consequently hinders the synthetic of ribonucleic acid, suppresses the growth of antibacterial, makes the bacteriostasis of sulphonamides can strengthen several times to tens times.And can reduce the appearance of Resistant strain.Clinical main share in the infection for the treatment of respiratory tract, urinary tract and soft tissue, as bronchitis, pneumonia, bacillary dysentery, meningitis, otitis media, pyelonephritis, enteritis and typhoid fever etc. with sulphonamides.
Aspirin:
Another name: Vinegar salicylic acid, aspirin, Baysprin add dimension C, Baysprin chewable tablet, bamyl (aspirin), Aspirin etc.
Effect and purposes:
1, is used for heating, headache, neuralgia, myalgia, rheumatic fever, acute rheumatic arthritis and rheumatoid arthritis etc., is rheumatic fever, rheumatic arthritis and rheumatoid arthritis drug of first choice, can alleviate the symptom of acute rheumatic arthritis rapidly., can share with myocarditis person acute rheumatic fever with 17-hydroxy-11-dehydrocorticosterone;
2, be used for gout;
3, prevention myocardial infarction, arterial thrombus, atherosclerosis etc.;
4, be used for the treatment of biliary ascariasis, effective percentage is more than 90%;
5, powder external can be controlled tinea pedis.
Nystatin:
Another name: Nystatin, Mycostatin, Fungicidine
Pharmacological toxicology: polyenoid class antifungal agent, the effect of tool broad-spectrum antifungal, to candidal antibacterial activity height, Cryptococcus histolyticus, aspergillosis, mucormycosis, sporidiole bacteria, the slurry born of the same parents of capsule tissue bacterium, Blastomyces dermatitidis and dermatophytosis are also responsive to this product usually.
This medicine can combine with the sterol on the fungal cell membrane, causes the change of permeability of cell membrane, so that the important cells content is missed and the performance antifungic action.
Oral medication digestive tract candidiasis intestinal inflammation; Topical application treatment oral cavity monilial infection, mucocutaneous monilial infection, vaginal candidiasis.
The optimum ratio of described raw material weight umber is:
Cinnabaris 3-4 part Borneolum Syntheticum 6-8 part Borax 5-8 part
Sulfamethoxazole 6-15 part trimethoprim 1-3 part
Aspirin 8-15 part nystatin 4-8 part
The best proportioning of described raw material weight umber is:
6 parts of 7 parts of Boraxs of 3 parts of Borneolum Syntheticums of Cinnabaris
2 parts of 8 parts of trimethoprims of Sulfamethoxazole
8 parts of 12 parts of nystatins of aspirin
The method of said medicine being made pharmaceutical composition of the present invention is:
Borax need be forged stir-fry, and porphyrize one-tenth is last respectively with said medicine with prior art, is mixed into powder then.
The white vaseline that adds 15-30 part in the above-mentioned powder that makes is mixed into cream, preferably 25 parts of the weight fractions of the white vaseline of its interpolation.
Pharmaceutical composition of the present invention, its usage is as follows:
External.To dipping, broken stain, rotten to the corn affected part, can directly spread on medicated powder; To have only desquamation, erythema, the directly affected part of drug of topical application powder such as chap, can use ointment to smear the affected part.
A kind of pharmaceutical composition for the treatment of tinea pedis and tinea corporis of the present invention compared with prior art, the beneficial effect that is produced is:
This technology is raw material with the Chinese medicine and western medicine, and with form of therapy tinea pedis (beriberi) and other tinea class such as the tinea corporis of medicine for external use, its raw material is easy to get, and prescription is simple, and price is low, and treating both the principal and secondary aspects of a disease, and sterilization is thorough, and removing dampness is strong, and antipruritic fast, effect is obvious, and thorough treatment is not recurred.
The specific embodiment:
Embodiment 1:
Cinnabaris 0.3 gram Borneolum Syntheticum 0.7 gram Borax 0.6 gram
Sulfamethoxazole 0.8 gram trimethoprim 0.12 gram
Aspirin 1.2 is restrained moldin 0.8 gram
After Borax is forged stir-fry, become last mixing to make said powder on the pharmaceutics said medicine porphyrize.
Embodiment 2:
Cinnabaris 0.2 gram Borneolum Syntheticum 0.5 gram Borax 0.4 gram
Sulfamethoxazole 1.1 gram trimethoprims 0.21 gram
Aspirin 1.7 is restrained moldin 0.5 gram
After Borax is forged stir-fry, become last mixing to make said powder on the pharmaceutics said medicine porphyrize, in above-mentioned powder, add 2.2 gram white vaseline and be mixed into unguentum.
Embodiment 3:
Cinnabaris 0.4 gram Borneolum Syntheticum 0.9 gram Borax 0.8 gram
Sulfamethoxazole 2.0 gram trimethoprims 0.28 gram
Aspirin 0.5 is restrained moldin 0.2 gram
After Borax is forged stir-fry, become last mixing to make said powder on the pharmaceutics said medicine porphyrize.
Embodiment 4:
Cinnabaris 0.3 gram Borneolum Syntheticum 0.8 gram Borax 0.9 gram
Sulfamethoxazole 1.8 gram trimethoprims 0.4 gram
Aspirin 1.5 is restrained moldin 0.3 gram
After Borax is forged stir-fry, become last mixing to make said powder on the pharmaceutics said medicine porphyrize, in above-mentioned powder, add 2.5 gram white vaseline and be mixed into unguentum.
Below be the some cases that " Sishui County tinea diagnosis and treatment institute " provided, so that its drug effect to be described.
Case 1: Sun Bo, the man, 41 years old, live Huang Gou township, Sishui County, December arrived my institute's diagnosis and treatment on the 29th in 04 year, and be diagnosed as split hand, medication: smear this medicament 2-3 time to the affected part every day, recovery from illness after 3 days.
Case 2: Li Aixia, the woman, 36 years old, live Huang Gou township, Sishui County Hua Cun, on November 16th, 04, be diagnosed as tinea pedis, medication: smeared this medicament 2-3 time to the affected part every day to my institute's diagnosis and treatment, recovery from illness after 5 days.
Case 3: Bao Ruixiang, the man, 15 years old, on August 10th, 04, be diagnosed as the tinea manuum, tinea pedis, medication: smeared this medicament 2-3 time to the affected part every day respectively, after 5-7 days, is almost recovered to my institute's diagnosis and treatment.
Case 4: Guo Fushui, the man, 44 years old, live east, Huang Gou township, Sishui County Hua Cun, on March 5th, 05, be diagnosed as tinea capitis, medication: smeared this medicament 2-3 time to the affected part every day to my institute's diagnosis and treatment, recovery from illness after 10 days.
Case 5: Han Xing, the woman, 15 years old, on March 12nd, 05 was diagnosed as sick the sending out in the double-legged centre of the palm of tinea pedis (dry and cracked) and locates to my institute's diagnosis and treatment, and area accounts for 1/2 of full sole greatly, medication: smear this medicament 2-3 time to the affected part every day, recovery from illness after 6 days.
Case 6: Lu is existing, the man, and 23 years old, live Huang Gou village, Huang Gou township, Sishui County, on November 3rd, 04, be diagnosed as tinea pedis, medication: smeared this medicament 2-3 time to the affected part every day to my institute's diagnosis and treatment, recovery from illness after 4 days.
Case 7: Lu Yingchun, the woman, 19 years old, on January 10th, 05 was diagnosed as tinea to my institute's diagnosis and treatment, sick sending out between face, finger and toe, medication: smear this medicament 2-3 time to the affected part every day, recovery from illness after 7 days.
Case 8: Dong Laiai, the man 43 years old, lives Huang Gou township, Sishui County and drills Ma Cun, on January 3rd, 05 was diagnosed as tinea pedis to my institute's diagnosis and treatment, sick sending out in sole, and the sufferer area accounts for preceding 2/3 of whole sole, and rotten to the corn ulceration, medication: smear this medicament 2-3 time to the affected part every day, recovery from illness after 6 days.
Case 9: Zhou section chief, man 50 years old, the cadre of Sishui County Highway Administration Bureau, on January 15th, 05, be diagnosed as tinea pedis, medication: smeared this medicament 2-3 time to the affected part every day to my institute's diagnosis and treatment, recovery from illness after 7 days.
Case 10: Sun Xiu, the woman, 18 years old, to live Huang Gou township, Sishui County and drill Ma Cun, on February 11st, 05 was diagnosed as tinea pedis to my institute's diagnosis and treatment, sick instep between toe, the instep affected part is rotten to the corn, and medication: smear this medicament 2-3 time to the affected part every day, recovery from illness after 5 days.
By above-mentioned 10 model cases, the conclusion that we draw is: this pharmaceutical composition can not only be treated tinea pedis, can also treat other tinea classes such as tinea corporis, and its treatment phase is short, the cure rate height, and the energy treating both the principal and secondary aspects of a disease is thoroughly killed fungus, does not recur after healing.
Claims (6)
1, a kind of pharmaceutical composition for the treatment of tinea pedis and tinea corporis is characterized in that, it is to be formed by the following weight proportion raw material:
Cinnabaris 2-4 part Borneolum Syntheticum 5-9 part Borax 4-9 part
Sulfamethoxazole 4-20 part trimethoprim 0.8-4 part
Aspirin 3-18 part nystatin 2-8 part
2, a kind of pharmaceutical composition for the treatment of tinea pedis and tinea corporis according to claim 1 is characterized in that the proportioning of described raw material weight umber is:
Cinnabaris 3-4 part Borneolum Syntheticum 6-8 part Borax 5-8 part
Sulfamethoxazole 6-15 part trimethoprim 1-3 part
Aspirin 8-15 part nystatin 4-8 part
3, a kind of pharmaceutical composition for the treatment of tinea pedis and tinea corporis according to claim 1 is characterized in that the proportioning of described raw material weight umber is:
6 parts of 7 parts of Boraxs of 3 parts of Borneolum Syntheticums of Cinnabaris
2 parts of 8 parts of trimethoprims of Sulfamethoxazole
8 parts of 12 parts of nystatins of aspirin
4, a kind of preparation of drug combination method as claim 1,2 or 3 described treatment tinea pedis and tinea corporis is characterized in that, becomes last mixing to make said powder on the pharmaceutics said medicine porphyrize.
5, a kind of preparation of drug combination method for the treatment of tinea pedis and tinea corporis according to claim 4 is characterized in that, the white vaseline that adds 15-30 part in above-mentioned powder is mixed into cream.
6, a kind of preparation of drug combination method for the treatment of tinea pedis and tinea corporis according to claim 5 is characterized in that, the white vaseline that adds 25 parts in above-mentioned powder is mixed into cream.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100426005A CN100352449C (en) | 2005-03-30 | 2005-03-30 | Medicament composition for treating tinea pedis and tinea corporis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100426005A CN100352449C (en) | 2005-03-30 | 2005-03-30 | Medicament composition for treating tinea pedis and tinea corporis |
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| Publication Number | Publication Date |
|---|---|
| CN1839882A true CN1839882A (en) | 2006-10-04 |
| CN100352449C CN100352449C (en) | 2007-12-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2005100426005A Expired - Fee Related CN100352449C (en) | 2005-03-30 | 2005-03-30 | Medicament composition for treating tinea pedis and tinea corporis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070911A (en) * | 2012-05-31 | 2013-05-01 | 张旭 | Foot fungus beriberi treatment powder |
| KR101913564B1 (en) * | 2017-09-19 | 2018-10-31 | 김금철 | Ointment composition for treatment of tinea pedis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1050287C (en) * | 1993-03-05 | 2000-03-15 | 中国人民解放军空军南京医院 | Medicine for treating infantile eczema and its preparing method |
| CN1261107C (en) * | 2002-07-18 | 2006-06-28 | 陈世宪 | Chinese medicine for treating eczema and dermatitis |
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2005
- 2005-03-30 CN CNB2005100426005A patent/CN100352449C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070911A (en) * | 2012-05-31 | 2013-05-01 | 张旭 | Foot fungus beriberi treatment powder |
| KR101913564B1 (en) * | 2017-09-19 | 2018-10-31 | 김금철 | Ointment composition for treatment of tinea pedis |
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| Publication number | Publication date |
|---|---|
| CN100352449C (en) | 2007-12-05 |
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Granted publication date: 20071205 Termination date: 20110330 |