CN1413601A

CN1413601A - Chinese medicine for compound circulation treatment of angiocardiopathy and cerebrovascular disease

Info

Publication number: CN1413601A
Application number: CN 01133339
Authority: CN
Inventors: 孟宪茹
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-10-22
Filing date: 2001-10-22
Publication date: 2003-04-30

Abstract

A Chinese medicine for treating cardiovascular and cerebrovascular diseases, hyperlipomia and hypertension is prepared from 32-34 Chinese-medicinal materials including Chinese angelica root, white peony root, arborvitae seed, scutellaria root, etc. Its advantage is radically curative effect.

Description

The Chinese medicine of compound circulation treatment of angiocardiopathy and cerebrovascular disease

The present invention relates to a kind of Chinese medicine for the treatment of cardiovascular and cerebrovascular disease.

At present the medicament categories of treatment cardiovascular and cerebrovascular disease is a lot, and they are to mitigate the disease, suppresses that sb.'s illness took a turn for the worse has certain effect, and the active drug of cardiovascular and cerebrovascular disease does not also occur at present but can thoroughly treat more.

Task of the present invention is: overcome the deficiencies in the prior art, propose a kind of Chinese medicine that can thoroughly effect a radical cure cardiovascular and cerebrovascular disease.

Task of the present invention realizes as follows: the Chinese medicine of compound circulation treatment of angiocardiopathy and cerebrovascular disease is to be made of following composition: 20 parts of (1) Radix Angelicae Sinensis, the Radix Paeoniae Alba 20 minutes, 20 parts of Semen Platycladi, Radix Scutellariae 20 minutes, 15 parts of Radix Scrophulariaes, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Rhizoma Coptidis, 15 parts of Fructus Forsythiaes, 15 parts in the Radix Rehmanniae, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Rhizoma Atractylodis, 12 parts of Cortex Albiziaes, 10 parts of Flos Buddlejaes, 15 parts of Radix Paeoniae Rubra, 20 parts of Spica Prunellaes, 15 parts of the Fructus Kochiae, 15 parts of Rhizoma Cyperi, 15 parts of the Radixs Polygoni Multiflori, 12 parts of Radix Polygalaes, 15 parts of Radix Achyranthis Bidentataes, 15 parts of Herba Ecliptaes, 20 parts of Radix Isatidiss, 15 parts of Radix Gentianaes, 10 parts of Herba Artemisiae Scopariaes, 15 parts of Radix Pseudostellariaes, 15 parts of Fructus Schisandrae Chinensis, 15 parts of male skins, Ji Guan spends 20 parts, 20 parts of the Cortexs Eucommiae, 12 parts of Rhizoma Chuanxiongs, 20 parts of Herba Patriniae, 15 parts of celery seeds, meat Cong Rong 15g, 10 parts of Rhizoma Polygonati Odorati, 20 parts of Herba Lycopi, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Rhizoma Cyperis, 15 parts of Fructus Gardeniaees, 15 parts of Cortex Lycii, 20 parts of Carapax Trionycis, core is 15 parts in strongly fragrant, 15 parts of Cortex Phellodendris, 15 parts in Poria, 8 parts of Rhizoma Alismatis, 15 parts of Herba Polygoni Avicularis, 20 parts of silver Radix Bupleuri, 15 parts of Fructus Schisandrae Chinensis, 15 parts of Radix Puerariaes.

It adds technology is that Carapax Trionycis, Yu Liren, the Radix Polygoni Multiflori respectively are ground into the end; Fructus Schisandrae Chinensis, Radix Ophiopogonis (oven dry); Other medicine oven dry is ground into the end, synthetic soybean grain size watertight ball.Consumption 10-30 grain, 2-3 time on the th, warm water is taken a course of treatment.

Cooperate and to go the Chinese medicine preparation of auxiliary treatment in the invention sometimes and be: 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 20 parts of Semen Platycladi, 20 parts of the Radixs Astragali, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts on Flos Carthami, 15 parts in Radix Rehmanniae Preparata, 10 parts of Radix Ginsengs, 10 parts of Cortex Cinnamomis, 15 parts of Radix Notoginseng, 15 parts of Radix Polygoni Multiflori, 15 parts of Radix Ophiopogonis, 15 parts of Semen Cuscutae, 15 parts of Herba Epimedii, 10 parts of Squama Manis, 10 parts of Poria cum Radix Pinis, 10 parts of Semen Euryaless, 15 parts of Rhizoma Coptidis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Radix Puerariaes, 15 parts of Olibanums, 15 parts of Myrrhas, 15 parts of benefit Adiantum monochlamys Eaton., 15 parts of Fructus Ligustri Lucidi, Ji Guan spends 10 parts, 15 parts of Cortex Phellodendris, 10 parts of volt Siberian cockleburs, 10 parts of Rhizoma Alismatis, 10 parts of dear heart blood, 15 parts of the Cortexs Eucommiae, 15 parts of Rhizoma Polygonati Odorati, 10 parts of Radix Polygalaes, 15 parts of Fructus Schisandrae Chinensis, obey 15 parts of sons, 15 parts of Ramulus Cinnamomi; Its processing technique is: Squama Manis, Rhizoma Coptidis, Radix Notoginseng singly are ground into the end; Fructus Corni, the Cortex Eucommiae, Fructus Foeniculi, Fructus Schisandrae Chinensis (structure Fructus Lycii) have been fried oven dry, respectively have been ground into end be used as medicine (refining bubble method); Other medicine oven dry is pulverized, and does Semen Glycines size watertight ball, consumption 15-30 grain, every day 2-3 time.

The present invention is owing to contain in the prescription: (1) Radix Angelicae Sinensis, but the hemopoietic reinforcing the heart, hold up void, dodge to decrease, the removing blood stasis tissue regeneration promoting, the effect that having enriches blood invigorates blood circulation; (2) Radix Paeoniae Alba, sour cold, ginseng is received and can be mended, sweet benefit acid receipts, the effect that has convergence and foster team to enrich blood; (3) Semen Platycladi, the reinforcing the heart QI invigorating, is more treated palpitation with fear at the arresting sweating intestine moistening, and the effect of tranquilizing by nourishing the heart arresting sweating intestine moistening is arranged; (4) Radix Scutellariae, the withered purte the white of bitter cold, clear large intestine has the effect of cooling blood for hemostasis; (5) Radix Scrophulariae, clear root-free anger, swollen clearly hectic fever due to YIN-deficiency, the kidney invigorating; (6) Rhizoma Anemarrhenae, heat can remove yearningly, and hectic fever due to YIN-deficiency has row, and productive cough can be relaxed, and the nourshing Yin and drynsessmoistening prescription effect of heat clearing away is arranged, and can remove warm excessive thirst; (7) Rhizoma Coptidis has heat clearing away order pupil, and thick intestinal ends the effect of jasmine, and it is prosperous to control heart-fire, antibiotic, antibacterial, has blood pressure lowering, function of gallbladder promoting, analgesic, abirritative effect again; (8) Fructus Forsythiae, bitter plug can be eliminated the pain poison, and gas gathers blood clotting, and hot its pursues yearningly, has antibiotic, heart tonifying diuresis, blood pressure lowering, town to tell the effect that protects the liver; (9) Radix Rehmanniae can be warm clearly, hectic fever due to YIN-deficiency bothers, the yin nourishing removing heat from blood, and the Gan Saizhi profit, fire is let out in bitter match, and the effect of YIN nourishing and the production of body fluid promoting, heat clearing away, removing heat from blood is arranged; (10) Rhizoma Atractylodis Macrocephalae, sweet temperature spleen invigorating stomach strengthening, antidiarrheal is removed temperature, and double quilt eliminates the phlegm painful abdominal mass by gas, and sweet dampness is turbid, and the gas that strengthens the spleen and stomach is arranged, the turbid antidiarrheal effect of bath temperatureization; (11) Rhizoma Atractylodis, the spleen strengthening and damp drying, the diaphoresis alleviating distention in middle-JIAO can remove the external rheumatism of society, and the temperature of stopping in kindization stagnates again; (12) Cortex Albiziae, sharp people's will is pacified dirty making eye bright, and has releasing gloomy, the effect of Disperse hepatic depression; (16) Fructus Kochiae has the effect of removing damp-heat in the urinary bladder tonneau urine; (17) Rhizoma Cyperi has that fast air to open is strongly fragrant, the pain relieving regulating menstruation more disappears dyspepsia, the hot hardship of loosing lets out liver-smoothing, qi-regulating, resolving depression, logical effect of transferring the three warmers stagnation of QI; (18) Carapax Trionycis, the effect of clearing away heat and cooling blood, promoting the production of body fluid to quench thirst; (19) Radix Polygalae has the effect of the relieving palpitation of calming the nerves; (20) silver-colored Radix Bupleuri wherein has and moves back cloudy branchs deficiency-heat and removing heat from blood removes the effect of steaming and the removing infantile malnutrition with fever being arranged; (21) Radix Cyathulae has invigorating the liver and kidney, the effect of bone and muscle strengthening and promoting blood circulation to restore menstrual flow.(22) Cortex Moutan has cool dissipating blood stasis; Promoting blood circulation to restore menstrual flow effect; (23) Fructus Gardeniae, the clear pathogenic fire purging heat of energy, the relieving restlessness that clears away heart-fire, and energy cooling blood for hemostasis, hemorrhages such as treatment bleeding due to blood-heat; (24) Cortex Phellodendri has bitter plug heat clearing and damp drying, and reducing the asthenic fever is protected the effect of cloudy liquid; (25) Rhizoma Alismatis has detumescence antidiarrheal, and the dehumidifying pain is drenched, and polyhidrosis around the external genitals is from the effect of meeting; (26) Flos Carthami has and invigorates blood circulation, the effect of clots absorbing blood.(27) Radix Gentianae has the effect of clearing away heat-fire; (28) mattress removes, and has the effect of function of gallbladder promoting, analgesic blood pressure lowering; (29) Poria can be eliminating evil, can set upright again, and the effect of spleen-benefiting mind-tranquilizing is arranged again; (30) Ji Guan flower has removing heat from blood, stops blooding, controls function such as hemorrhoid hematochezia; (31) Radix Astragali, the energy absorbing sweat can fill blood again because of table, granulation promoting; (32) Radix Bupleuri, energy removing fire from the liver, expelling pathogenic factors from muscles heat; (33) Radix Notoginseng, energy stopping bleeding and removing blood stasis, subduing swelling and relieving pain; (34) Rhizoma Chuanxiong has promoting blood circulation to restore menstrual flow, removes cold circulation of qi promoting, the wind analgesic effect of loosing; (35) Radix Stellariae, clearing away heat and cooling blood removes hectic fever due to YIN-deficiency; (36) Fructus Ligustri Lucidi has the effect of tonification liver, stomach, positive blood and clearind deficient heat.(37) Radix Et Rhizoma Rhei, removing pathogenic heat from blood and toxic substance from the body, is stimulated the menstrual flow at removing blood stasis; (38) celery seed, the blood pressure lowering removing heat from blood; (39) Radix Arnebiae (Radix Lithospermi), the effect of logical stool of energy laxation and inducing diuresis to remove edema; (40) Radix Isatidis has heat-clearing and toxic substances removing, the effect of removing heat from blood sore-throat relieving; (41) Cortex Cinnamomi has supporing yang dispersing cold for relieving pain, the effect of warm promoting blood circulation; (42) Herba Epimedii has the kidney invigorating and essence nourishing tonifying YANG to play flaccidity; (43) Semen Cuscutae has invigorating the liver and kidney, the effect of beneficial marrow, strengthening bone and muscle; (44) shredded meat holds, and stronger benefit extensive cultivation blood effect is arranged; (45) Radix Polygoni Multiflori has the kidney invigorating and essence nourishing, strengthens the effect of reproductivity; (46) Semen Euryales: the effect of the kidney invigorating and essence nourishing is arranged; (47) Cortex Eucommiae, invigorating the liver and kidney, strengthening bone and muscle; (48) Rhizoma Polygonati Odorati has the effect of strengthening heart and boosting pressure; (49) dear heart blood, invigorating kidney-YANG, benefiting essence-blood, invigorating middle warmer gas; (50) Radix Ginseng replenishes gas, benefiting qi and supporting yang greatly; (51) have the treatment deficiency of stomach-Yin Radix Ophiopogonis, the effect that dry tongue is thirsty; (52) Radix Salviae Miltiorrhizae, but treatment belt reaches gynaecopathia down; (53) Squama Manis has detumescence, evacuation of pus, the effect of milk down; (54) Poria cum Radix Pini, reinforcing the heart is relieving convulsion throbs with fear; (55) the benefit man is careless, and the effect of promoting blood flow to regulate menstruation is arranged; (56) outer wall of a city perfume (or spice) has blood circulation promoting regulates qi, the effect of pain relieving granulation promoting; (57) Myrrha has the effect of eliminating stasis to stop pain; (58) Radix Puerariae has ailment said due to cold or exposure and the analgesic effect of promoting the production of body fluid of dispersing; (59) Herba Patriniae has the effect of inhibitory anti-virus, can promote the regeneration of cell.

Only state the comprehensive function of every Chinese medicine, can make an overall screening that heat in blood, removing heat from blood, collateral dredging, detoxifcation, vessel softening, blood-heat type, hypertension, shortness of breath and palpitation, tachycardias YIN nourishing fall that blood refers to, liver heat removing function of gallbladder promoting, reason spleen, penetrating blood vessel, defeated the meridian dredging, hypermnesis, treatment by principal agent, blood cools down, and takes auxiliary therapeutic agent and reaches equilibrium between yin and yang, the comprehensive rehabilitation of body constitution.On the basis of main formula, take auxilliary side, the cardiovascular and cerebrovascular disease of compound microcirculation treatment of the present invention like this is a kind of benefit therapy, and it can systematically regulate heart and brain, liver and gall, spleen, lung, stomach comprehensively, carries out the systemic circulation method, from the beginning arrive sufficient blood, body fluid gas systemic circulation method; The promotion blood vessels flow, antithrombotic, platelet aggregation and thrombus improve diseases such as chest pain, uncomfortable in chest, cardiopalmus, dizziness, insomnia, forgetful, soreness of the waist and knees, four numbnesses be weak rapidly, thoroughly change morbid state by microcirculation, improve the logical show of cardiovascular and cerebrovascular vessel, the immunity of enhancing body.

A most preferred embodiment of the present invention is got Radix Angelicae Sinensis 20g, the Radix Paeoniae Alba 20 minutes, Semen Platycladi 20g, Radix Scutellariae 20 minutes, Radix Scrophulariae 15g, Rhizoma Anemarrhenae 15g, Rhizoma Coptidis 15g, Fructus Forsythiae 15g, Radix Rehmanniae 15g, Rhizoma Atractylodis Macrocephalae 15g, Rhizoma Atractylodis 10g, Cortex Albiziae 12g, Flos Buddlejae 10g, Radix Paeoniae Rubra 15g, Spica Prunellae 20g, Fructus Kochiae 15g, Rhizoma Cyperi 15g, Radix Polygoni Multiflori 15g, Radix Polygalae 12g, Radix Achyranthis Bidentatae 15g, Herba Ecliptae 15g, Radix Isatidis 20g, Radix Gentianae 15g, Herba Artemisiae Scopariae 10g, Radix Pseudostellariae 15g, Fructus Schisandrae Chinensis 15g, male skin 15g, Ji Guan flower 20g, Cortex Eucommiae 20g, Rhizoma Chuanxiong 12g, Herba Patriniae 20g, celery seed 15g, meat Cong Rong 15g, Rhizoma Polygonati Odorati 10g, Herba Lycopi 20g, Radix Arnebiae (Radix Lithospermi) 10g, Rhizoma Cyperi 15g, Fructus Gardeniae 15g, Cortex Lycii 15g, Carapax Trionycis 20g, core 15g in strongly fragrant, Cortex Phellodendri 15g, Poria 15g, Rhizoma Alismatis 8g, Herba Polygoni Avicularis 15g, silver Radix Bupleuri 20g, Fructus Schisandrae Chinensis 15g, Radix Puerariae 15g.

Radix Angelicae Sinensis Radix Angelicae Sinensis 20g is got in the attached making that helps medicine, Radix Paeoniae Alba 20g, Semen Platycladi 20g, Radix Astragali 20g, Radix Salviae Miltiorrhizae 15g, Flos Carthami 20g, Radix Rehmanniae Preparata 15g, Radix Ginseng 10g, Cortex Cinnamomi 10g, Radix Notoginseng 15g, Radix Polygoni Multiflori 15g, Radix Ophiopogonis 15g, Semen Cuscutae 15g, Herba Epimedii 15g, Squama Manis 10g, Poria cum Radix Pini 10g, Semen Euryales 10g, Rhizoma Coptidis 15g, Rhizoma Chuanxiong 15g, Radix Puerariae 15g, Olibanum 15g, Myrrha 15g, benefit Adiantum monochlamys Eaton. 15g, Fructus Ligustri Lucidi 15g, Ji Guan flower 10g, Cortex Phellodendri 15g, volt Siberian cocklebur 10g, Rhizoma Alismatis 10g, dear heart blood 10g, Cortex Eucommiae 15g, Rhizoma Polygonati Odorati 15g, Radix Polygalae 10g, Fructus Schisandrae Chinensis 15g, obey sub-15g, Ramulus Cinnamomi 15g; Its processing technique is: Squama Manis, Rhizoma Coptidis, Radix Notoginseng singly are ground into the end; Fructus Corni, the Cortex Eucommiae, Fructus Foeniculi, Fructus Schisandrae Chinensis (structure Fructus Lycii) have been fried oven dry, respectively have been ground into end be used as medicine (refining bubble method); Other medicine oven dry is pulverized, and does Semen Glycines size watertight ball, consumption 15-30 grain, every day 2-3 time.

In conjunction with zoopery, clinical experiment pharmacological effect of the present invention is described.

One, chmice acute toxicity test

Get 10 of mices, body gets the 10-22 gram, and male and female all have, press 30 times of oral administrations of people's oral dose, administration is forward and backward weighs respectively, observes mice diet, activity and fur situation in the administration process, successive administration 7 days, the result is no abnormal, and body gets to some extent to be increased.

Two, the rabbit immune function experiment is observed

Get four of large ear rabbits, body weight is divided into two groups about 2.5 kilograms, one group is matched group, and one group is the administration group, and administration group dosing per capita connected oral administration 15 days for 5 times, matched group is with advancing to take normal saline, put to death animal on the 16th day, and got the equal sheet dyeing microscopic examination of internal organs, two groups compare, the obvious hypertrophy of white pulp in the spleen as a result, phagocyte increase function is active in the red pulp, and acidocyte increases, and shows that the present invention has the raising immunity function.

Three, clinical experiment

Carry out random packet to drawing routine cardiovascular patient, the treatment group is taken medicine of the present invention, and matched group adopts Therapeutic Method in the past, and both the clinical observation treatment group was to remarkable according to the group effect.

Claims

1. the Chinese medicine of a compound circulation treatment of angiocardiopathy and cerebrovascular disease, it is characterized in that: each becomes proportioning to be: (1) Radix Angelicae Sinensis 20g, the Radix Paeoniae Alba 20 minutes, Semen Platycladi 20g, Radix Scutellariae 20 minutes, Radix Scrophulariae 15g, Rhizoma Anemarrhenae 15g, Rhizoma Coptidis 15g, Fructus Forsythiae 15g, Radix Rehmanniae 15g, Rhizoma Atractylodis Macrocephalae 15g, Rhizoma Atractylodis 10g, Cortex Albiziae 12g, Flos Buddlejae 10g, Radix Paeoniae Rubra 15g, Spica Prunellae 20g, Fructus Kochiae 15g, Rhizoma Cyperi 15g, Radix Polygoni Multiflori 15g, Radix Polygalae 12g, Radix Achyranthis Bidentatae 15g, Herba Ecliptae 15g, Radix Isatidis 20g, Radix Gentianae 15g, Herba Artemisiae Scopariae 10g, Radix Pseudostellariae 15g, Fructus Schisandrae Chinensis 15g, male skin 15g, Ji Guan flower 20g, Cortex Eucommiae 20g, Rhizoma Chuanxiong 12g, Herba Patriniae 20g, celery seed 15g, meat Cong Rong 15g, Rhizoma Polygonati Odorati 10g, Herba Lycopi 20g, Radix Arnebiae (Radix Lithospermi) 10g, Rhizoma Cyperi 15g, Fructus Gardeniae 15g, Cortex Lycii 15g, Carapax Trionycis 20g, core 15g in strongly fragrant, Cortex Phellodendri 15g, Poria 15g, Rhizoma Alismatis 8g, Herba Polygoni Avicularis 15g, silver Radix Bupleuri 20g, Fructus Schisandrae Chinensis 15g, Radix Puerariae 15g.

2. the attached medicine that helps of the Chinese medicine of a compound circulation treatment of angiocardiopathy and cerebrovascular disease, it is characterized in that: each becomes the proportioning of g to be: Radix Angelicae Sinensis 20g, Radix Paeoniae Alba 20g, Semen Platycladi 20g, Radix Astragali 20g, Radix Salviae Miltiorrhizae 15g, Flos Carthami 20g, Radix Rehmanniae Preparata 15g, Radix Ginseng 10g, Cortex Cinnamomi 10g, Radix Notoginseng 15g, Radix Polygoni Multiflori 15g, Radix Ophiopogonis 15g, Semen Cuscutae 15g, Herba Epimedii 15g, Squama Manis 10g, Poria cum Radix Pini 10g, Semen Euryales 10g, Rhizoma Coptidis 15g, Rhizoma Chuanxiong 15g, Radix Puerariae 15g, Olibanum 15g, Myrrha 15g, benefit Adiantum monochlamys Eaton. 15g, Fructus Ligustri Lucidi 15g, Ji Guan flower 10g, Cortex Phellodendri 15g, volt Siberian cocklebur 10g, Rhizoma Alismatis 10g, dear heart blood 10g, Cortex Eucommiae 15g, Rhizoma Polygonati Odorati 15g, Radix Polygalae 10g, Fructus Schisandrae Chinensis 15g, obey sub-15g, Ramulus Cinnamomi 15g;