CN1410112A - Fuyuan plaster for promoting blood circulation - Google Patents
Fuyuan plaster for promoting blood circulation Download PDFInfo
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- CN1410112A CN1410112A CN 02147718 CN02147718A CN1410112A CN 1410112 A CN1410112 A CN 1410112A CN 02147718 CN02147718 CN 02147718 CN 02147718 A CN02147718 A CN 02147718A CN 1410112 A CN1410112 A CN 1410112A
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- promoting blood
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Abstract
A plaster for treating ischemic femur head necrosis is prepared from the composite medicine powder and decocted vegetable oil through mixing in Wt. ratio of (1-2.4):60. The said composite medicine powder is prepared from 20 Chinese medicinal materials including notoginseng, Chinese angelica root, safflower, red sage root, etc.. Its advantages are high curative effect and low cost.
Description
(1) technical field
The present invention relates to the Chinese medicine field, relate in particular to a kind of Fuyuan plaster for promoting blood circulation of ischemic necrosis of femoral head due to the treatment a variety of causes that is applicable to.
(2) background technology
Femur head necrosis is the dead caused pathological process of composition alive (osteocyte, medullary cell and adipose cell) of bone, all can cause osteonecrosis as the wound of hip joint, some drugs (as adrenocortical hormone), multiple disease, chronic alcoholism etc.The key problem of femur head necrosis is the disturbance of blood circulation of the bone that causes of a variety of causes.It is generally acknowledged that osteonecrosis constantly developed through each stage, can cause the femoral head weight-bearing surface partly to subside, cause the hip joint degenerative osteoarthritis at last.Osteonecrosis is carried out phase to degenerative osteoarthritis needs 3~5 years late period.This disease is hip pain, dysfunction, limbs shortening to the direct influence of human body.This disease belongs to one of clinical difficult disease, and primary disease is more common in 30~50 years old, has half to involve bilateral femoral head approximately, recently, because the human diseases spectrum changes, the incidence rate of Avascular Necrosis Of Femur Head is tending towards raising, and show according to interrelated data: the U.S. had 1.5~30,000 new patients approximately in 1992; 1998, there were 2500~3000 example morbidities in Japan.The nineteen ninety relevant expert reveals at " healthy newspaper " work literary composition: at that time, China had 580,000 people that femur head necrosis takes place approximately.Osteonecrosis patient increased to 1,000,000 people according to hygiene department's incomplete statistics in 2000.These have caused that all medical profession payes attention to widely.
The purpose of Avascular Necrosis Of Femur Head treatment is to remove or alleviating pain, recovers hip joint function, reduces or avoids cacomelia.The Therapeutic Method that adopts mainly is a surgical operation at present, comprises that hip replacement, femoral head boring decompression method, blood vessel art are shifted and insert, be with the transplanting of base of a fruit ilium, part synovectomy and various osteotomies etc.Follow up a case by regular visits to data the long term that still lacks objective indicator and capacity for the judgement of operative effect; And also there are two problems that must face in the surgical operation therapy: the one, and expense height, artificial replacement's femoral head general expenses are 3~50,000 yuan, and need perform a surgical operation once more every 5~8 years, the patient bears painful big, and the 2nd, the relapse rate height.With regard to present China town and country people's level of consumption and treatment custom, beyond affordability to the operation of artificial replacement's femoral head.
Discussion can stop the development of femur head necrosis, impels the femoral head blood circulation, and its pathological changes is disappeared, and recovers hip joint function, is the key subjects of clinical at present and basic research work.
(3) summary of the invention
Purpose of the present invention just is being based on existing problem in the above-mentioned prior art and a kind of Fuyuan plaster for promoting blood circulation that is specifically designed to the treatment ischemic necrosis of femoral head of studying preparation, uses this plaster treatment expense low, no pain, and treating both the principal and secondary aspects of a disease, and therapeutic effect is good.
The objective of the invention is to realize by following scheme:
This Fuyuan plaster for promoting blood circulation be by composition of medicine powder and the vegetable oil that boils by 1~2.4: the mixed of 60 (weight ratios) forms, wherein composition of medicine by following component by weight formulated:
Radix Notoginseng 3.5~4.4% Radix Angelicae Sinensis 5.2~6.2% Flos Carthamis 5.4~6.3%
Radix Salviae Miltiorrhizae 4.9~5.8% Olibanums (system) 3.4~4.3% Myrrha (processed) 3.6~4.5%
Sanguis Draxonis 2.1~3.2% Caulis Spatholobis 5.7~6.6% Radix Aconiti Preparatas 2~3%
Radix Aconiti Kusnezoffii Preparata 2.1~3.2% Radix Cyathulaes 5.6~6.5% Fructus Chaenomeliss 5.4~6.3%
Rhizoma Et Radix Notopterygii 5.3~6.3% Radix Angelicae Pubescentiss 5.7~6.8% Radix Clematidis 5.6~6.5%
Rhizoma Drynariae 5.5~6.4% Radix Rehmanniae Preparata 5.5~6.6% Cortexs Eucommiae 5.4~6.3%
Fructus Gleditsia 3.7~4.6% Borneolum Syntheticums 7.6~8.4%
Vegetable oil of the present invention is preferably little mill oil, also can be added with a spot of Oleum Arachidis hypogaeae semen therein.
Fuyuan plaster for promoting blood circulation of the present invention be on clinical observation basis for many years and form through proved recipe, aspect Study on Preparation, at first consider respectively to distinguish the flavor of in the prescription physicochemical property of pharmaceutically active ingredient, Radix Angelicae Sinensis, Radix Angelicae Pubescentis contain volatile effective component, so adopt cold drying when oven dry; Sanguis Draxonis is the hard medical material of quality, should smash the back remix before pulverizing and pulverize.Borneolum Syntheticum is the LMP medical material, mixes to pulverize then and easily pastes, so adopt porphyrize, mixes with medicated powder again, and mixes the back and adopt cover to grind, in order to avoid mix inhomogeneous.For guaranteeing the inherent quality of this product, we adopt the microscopical identification method that Flos Carthami, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Cyathulae, Caulis Spatholobi are carried out micrography respectively, adopting tlc identification method that principal agent Radix Notoginseng in the prescription is carried out the thin layer inspection knows, and to virose medicine in the prescription, Radix Aconiti, Radix Aconiti Kusnezoffii have carried out the thin layer inspection and have known.
Its preparation technology is as follows:
1, Olibanum, Myrrha, Sanguis Draxonis are that oleo-gum-resin class Chinese medicine, oven dry easily make effective ingredient lose, and also make the medicine deliquescing, so dry processing; It is volatility that Borneolum Syntheticum contains effective composition, is difficult for oven dry, easy coherent mass when pulverizing separately, so when handling and other medicines mix and pulverize or facing-up.
2, to contain effective composition be volatile ingredient for Radix Angelicae Pubescentis, Radix Angelicae Sinensis, should do cold drying before pulverizing.
3, Borneolum Syntheticum is a small dose drug in the prescription, adopts facing-up to handle when therefore mixing with other medicines.
4, above-mentioned each herbal medicine is ground into fine powder (crossing more than 80 mesh sieves), so that the absorption of effective ingredient.
5, put in the iron pan with little mill oil, heat to 280~350 degrees centigrade, high temperature boils, and waits to drip into the pearl degree, and above-mentioned fine powder is stirred evenly by 60: 1~2.4 mixed, the collection of cold back.During use, cream is applied to is attached to the affected part on the cloth and gets final product.
Prescription analysis:
Make a general survey of full side, this side establishes for Avascular Necrosis Of Femur Head.The Radix Notoginseng sweet and slightly bitter taste is warm in nature in the side, blood circulation promoting and blood stasis dispelling, and subduing swelling and relieving pain hemostasis, clots absorbing blood and hold back fresh blood, all blood stasis are all broken, and all fresh blood then end, and are monarch drug.Radix Angelicae Sinensis, Flos Carthami, Radix Salviae Miltiorrhizae, Olibanum, Myrrha, Sanguis Draxonis, Caulis Spatholobi promoting blood circulation and stopping pain, promoting of the circulation of QI and removing the obstruction in the collaterals is ministerial drug, share with monarch drug and brings out the best in each other, and with the medicine-feeding pain relieving, needs the detailed cause of disease of examining pain, has wind to dispel the wind, and cold cold relieving is arranged, and has wet reason wet.So get Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata acrid in the mouth, extremely hot in nature, remove cold open numbness, removing mass eliminating stagnation; Radix Cyathulae, Fructus Chaenomelis relaxing muscles and tendons and activating QI and blood in the collateral, the wet reason of reason spleen; Rhizoma Et Radix Notopterygii, the hot temperature of Radix Angelicae Pubescentis are dispersed, and can dispel the wind and win temperature, rise Taiyang channel and governor vessel yang-energy; The Radix Clematidis acrid in the mouth becomes, and its property is apt to away, nowhere less than, can declare logical the five internal organs, twelve channels and collaterals, holding concurrently can the expectorant removing food stagnancy; Rhizoma Drynariae, Radix Rehmanniae Preparata, Cortex Eucommiae invigorating the kidney and strengthening the bones, YIN nourishing is given birth to marrow; The Fructus Gleditsia blood circulation promoting and dispersing pathogen accumulation is had one's ideas straightened out and is searched wind, and expectorant is long-pending, and the Tuoli is poison thoroughly, is adjuvant drug altogether; Borneolum Syntheticum acrid in the mouth hardship, cold nature, perfume (or spice) is scurried and is apt to away, nowhere less than, can declare the QI and blood of loosing, logical all keys, the walk help efficacy of a drug, row medicine gesture is to be messenger drug.Each medicine share, and the blood stasis bone is given birth to, the capable ruton of gas, then hip pain self-balancing, promptly so-called " person of going goes, and the survivor gives birth to, and pain is from easypro and first runback ".Full side plays blood circulation promoting and blood stasis dispelling altogether, promoting of the circulation of QI and removing the obstruction in the collaterals, and invigorating the kidney and strengthening the bones, expelling wind and cold, the Tuoli is poison thoroughly, the relieving spasm to stop pain effect.
The advantage that the present invention is possessed compared to existing technology is: non-operative treatment, the external application plaster, expense is low, the patient is no pain in therapeutic process, and treating both the principal and secondary aspects of a disease, effective, be applicable to all kinds of crowds, also solved existing in medical interior application treatment should disease, some should not take the difficult problem of oral medicine for a long time because of gastrointestinal upset or pregnancy women.
(4) the present invention is further described below in conjunction with embodiment, but does not limit the present invention.
Embodiment 1:
Take off in proportion and state medicine:
Radix Notoginseng 4%, Radix Angelicae Sinensis 5.5%, Flos Carthami 5.4%, Radix Salviae Miltiorrhizae 5%, Olibanum (system) 4%, Myrrha (processed) 4%, Sanguis Draxonis 2.8%, Caulis Spatholobi 6%, Radix Aconiti Preparata 2.5%, Radix Aconiti Kusnezoffii Preparata 2.7%, Radix Cyathulae 6%, Fructus Chaenomelis 5.5%, Rhizoma Et Radix Notopterygii 5.5%, Radix Angelicae Pubescentis 6.2%, Radix Clematidis 6%, Rhizoma Drynariae 5.9%, Radix Rehmanniae Preparata 6%, the Cortex Eucommiae 5.4%, Fructus Gleditsia 3.8%, Borneolum Syntheticum 7.8%
With wherein some medicines through following conventional treatment: Olibanum, Myrrha, Sanguis Draxonis dry processing; Radix Angelicae Pubescentis, Radix Angelicae Sinensis cold drying are handled, and adopt facing-up to handle when Borneolum Syntheticum should mix with other medicines.
Above-mentioned 20 flavor medicated powder are broken into fine powder, cross more than 80 mesh sieves, mix homogeneously heats little mill oil to 280~330 °, boils about 10 hours, reach the pearl degree of dripping into, the ratio of above-mentioned medicated powder in 1.5: 60 added in the oil mix homogeneously, the collection of cold back, be coated in during use on the cloth, be affixed on the affected part and get final product.
Embodiment 2:
Take off in proportion and state medicine:
Radix Notoginseng 3.8%, Radix Angelicae Sinensis 5.8%, Flos Carthami 5.4%, Radix Salviae Miltiorrhizae 5%, Olibanum (system) 3.7%, Myrrha (processed) 3.8%, Sanguis Draxonis 2.4%, Caulis Spatholobi 6.4%, Radix Aconiti Preparata 2.2%, Radix Aconiti Kusnezoffii Preparata 2.7%, Radix Cyathulae 6.3%, Fructus Chaenomelis 5.8%, Rhizoma Et Radix Notopterygii 5.6%, Radix Angelicae Pubescentis 5.8%, Radix Clematidis 5.8%, Rhizoma Drynariae 6.1%, Radix Rehmanniae Preparata 6.2%, the Cortex Eucommiae 5.4%, Fructus Gleditsia 3.8%, Borneolum Syntheticum 8%
With wherein some medicines through following conventional treatment: Olibanum, Myrrha, Sanguis Draxonis dry processing; Radix Angelicae Pubescentis, Radix Angelicae Sinensis cold drying are handled, and adopt facing-up to handle when Borneolum Syntheticum should mix with other medicines.
Above-mentioned 20 flavor medicated powder are broken into fine powder, cross more than 80 mesh sieves, mix homogeneously (can add some Oleum Arachidis hypogaeae semen therein with little mill oil, account for 1/4) heat to 280~330 °, boil about 10 hours, reach the pearl degree of dripping into, the ratio of above-mentioned medicated powder in 1.8: 60 added in the oil, mix homogeneously, the collection of cold back is coated in during use on the cloth, is affixed on the affected part and gets final product.
Clinical testing data
The patient is divided into treatment group and matched group, and 100 examples are organized in treatment, matched group 50 examples.
Test method:
1, with the grouping contrast method, by the random digit random packet, matched group and test group ratio are 1: 2.
2, treatment group: at patient's groin place and HUANTIAO acupoint place external application Fuyuan plaster for promoting blood circulation of the present invention paste, applied ointment or plaster every day 10 hours.
3, matched group: at patient's groin place and HUANTIAO acupoint place external application YUNNAN BAIYAO plaster, applied ointment or plaster every day 10 hours.
4, the course of treatment: be three months.
Therapeutic effect shows that this post-equalization is invigorated blood circulation and pasted treatment ischemic necrosis of femoral head cure rate is 61%, and improvement rate is 32%, total effective rate 93%; The matched group cure rate is 16%, and improvement rate is 40%, total effective rate 56%.
Acute dermal toxicity result of the test: select each 15 of rat male and female, adopt horn method to test, the drug of topical application time is 24 hours, remove dressing after 24 hours, and wash away the residual thing that tried with deionized water, observe a week continuously, the contamination back is female, tom all has movable slow phenomenon, second day all no abnormal phenomenon of observation animal.Observe none example death of a week.Fuyuan plaster for promoting blood circulation plaster of the present invention is real to belong to nontoxic grade.
Claims (2)
1, a kind of Fuyuan plaster for promoting blood circulation is characterized in that: it be by composition of medicine powder and the vegetable oil that boils by 1~2.4: the mixed of 60 (weight ratios) forms, wherein the composition of medicine powder by following component by weight formulated:
Radix Notoginseng 3.5~4.4% Radix Angelicae Sinensis 5.2~6.2% Flos Carthamis 5.4~6.3%
Radix Salviae Miltiorrhizae 4.9~5.8% Olibanums (system) 3.4~4.3% Myrrha (processed) 3.6~4.5%
Sanguis Draxonis 2.1~3.2% Caulis Spatholobis 5.7~6.6% Radix Aconiti Preparatas 2~3%
Radix Aconiti Kusnezoffii Preparata 2.1~3.2% Radix Cyathulaes 5.6~6.5% Fructus Chaenomeliss 5.4~6.3%
Rhizoma Et Radix Notopterygii 5.3~6.3% Radix Angelicae Pubescentiss 5.7~6.8% Radix Clematidis 5.6~6.5%
Rhizoma Drynariae 5.5~6.4% Radix Rehmanniae Preparata 5.5~6.6% Cortexs Eucommiae 5.4~6.3%
Fructus Gleditsia 3.7~4.6% Borneolum Syntheticums 7.6~8.4%
2, Fuyuan plaster for promoting blood circulation according to claim 1 is characterized in that: described vegetable oil is little mill oil.
Priority Applications (1)
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CNB021477183A CN1164323C (en) | 2002-11-20 | 2002-11-20 | Fuyuan plaster for promoting blood circulation |
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CNB021477183A CN1164323C (en) | 2002-11-20 | 2002-11-20 | Fuyuan plaster for promoting blood circulation |
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CN1410112A true CN1410112A (en) | 2003-04-16 |
CN1164323C CN1164323C (en) | 2004-09-01 |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1320900C (en) * | 2005-04-01 | 2007-06-13 | 郭永昌 | Bone erosion renewel pill |
CN101879261A (en) * | 2010-06-23 | 2010-11-10 | 王平 | Medicinal paste for treating ischemic necrosis in head of femur |
CN103230462A (en) * | 2013-05-13 | 2013-08-07 | 戴静宜 | Pain tincture for physiotherapeutic transdermal absorption and treatment of acute and chronic pains |
CN104940796A (en) * | 2014-03-24 | 2015-09-30 | 姚震威 | Traditional Chinese medicine composition for promoting blood circulation to remove blood stasis and relieving swelling and pain |
CN109893607A (en) * | 2017-12-07 | 2019-06-18 | 王宏跃 | Transdermal steaming bone ointment |
-
2002
- 2002-11-20 CN CNB021477183A patent/CN1164323C/en not_active Expired - Fee Related
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1320900C (en) * | 2005-04-01 | 2007-06-13 | 郭永昌 | Bone erosion renewel pill |
CN101879261A (en) * | 2010-06-23 | 2010-11-10 | 王平 | Medicinal paste for treating ischemic necrosis in head of femur |
CN103230462A (en) * | 2013-05-13 | 2013-08-07 | 戴静宜 | Pain tincture for physiotherapeutic transdermal absorption and treatment of acute and chronic pains |
CN104940796A (en) * | 2014-03-24 | 2015-09-30 | 姚震威 | Traditional Chinese medicine composition for promoting blood circulation to remove blood stasis and relieving swelling and pain |
CN104940796B (en) * | 2014-03-24 | 2018-09-11 | 姚震威 | A kind of Chinese medicine composition of swelling and pain relieving promoting blood circulation and removing blood stasis |
CN109893607A (en) * | 2017-12-07 | 2019-06-18 | 王宏跃 | Transdermal steaming bone ointment |
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Publication number | Publication date |
---|---|
CN1164323C (en) | 2004-09-01 |
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Granted publication date: 20040901 |