CN1406599A - Process for producing medicine or health-care food from abalone shells - Google Patents
Process for producing medicine or health-care food from abalone shells Download PDFInfo
- Publication number
- CN1406599A CN1406599A CN01127161A CN01127161A CN1406599A CN 1406599 A CN1406599 A CN 1406599A CN 01127161 A CN01127161 A CN 01127161A CN 01127161 A CN01127161 A CN 01127161A CN 1406599 A CN1406599 A CN 1406599A
- Authority
- CN
- China
- Prior art keywords
- concha haliotidis
- hydrolyzed
- haliotidis
- concha
- health food
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A process for preparing medicine or health-care food from sea-ear shell includes such steps as decocting to obtain decoction, hydrolyzing the decocted sea-ear shell wile organic acid, concentrating, crystallizing to separate out calcium salt of organic acid, and mixing the mother liquid with said decoction. Its advantages are high utilization rate and simple process.
Description
Technical field
The present invention relates to a kind of processing technique of traditional Chinese medical science medicine, particularly relate to a kind of processing technique of producing medicine or health food with Concha Haliotidis (abalone shell).
Background technology
Concha Haliotidis (abalone shell) is the ophthalmology key medicine in the traditional Chinese medical science, its function is suppressing the hyperactive liver and subsiding YANG, makes eye bright, cure mainly diseases such as dizzy, the glaucoma of headache, hypertension retinal hemorrhage, cataract, keratitis and optic neuritis, it also can be respectively applied for treatment pulmonary tuberculosis low grade fever with different drug matching and not move back, and controls diseases such as hepatasthenia dim eyesight and Huan order nyctalopia.Because of Concha Haliotidis (abalone shell) contains more nacre, wherein comprised angle glutelin composition, so the same effect that skin care is also arranged with Margarita, its calcium content also is that of calcium replenishing well originates up to about 37%.In addition, also contain various trace element and trace element in the abalone shells as magnesium, manganese, strontium, copper, aluminum, ferrum, tungsten, zinc, barium, chromium, nickel, cobalt, silver, gold, titanium, silicon, lithium, iodine, bromine, thorium, lanthanum, scandium, selenium etc., wherein have quite a few trace element often human body lack and the material that need obtain replenishing, these trace element all can not be synthesized by human body oneself.Therefore, can think that Concha Haliotidis (abalone shell) is one of ideal trace element supplies of people.Because at present relevant process technology is still untapped, thereby health cares such as Concha Haliotidis (abalone shell) makes eye bright, replenishes the calcium, skin care still are underutilized so far.
Along with the appearance of TV and computer and more and more universal, the modern increases greatly with eye intensity, and vision suddenly must be protected, and eyes need health care, yet the natural health-care products of this respect is very few at present.Up-to-date achievement in research also shows the Concha Haliotidis hydrolyzed solution to improving the function of animal livers, and improving anti-fatigue ability all has remarkable result.The medicinal method of traditional Concha Haliotidis (abalone shell) is that the Concha Haliotidis water is decocted for a long time, perhaps calcining pulverize uses, these usages are not only processed consuming time, and can't make full use of whole effective ingredient of Concha Haliotidis, utilization ratio of raw materials is very low, makes resource produce very big waste, in addition, also can produce the nacre albumen of more waste pollution environment, particularly present known Concha Haliotidis and chitosan class material etc. also can't reasonably be made full use of.Other methods are used as soluble pearl powder or calsium supplement after just using acid or enzyme with complete hydrolysis such as shells, this kind method can make some compositions that have medical value originally be destroyed by acid or enzyme prematurely, for example have the nacre protein small peptide of health care or oligo-chitosan isoreactivity material all because of exceedingly being hydrolyzed into aminoacid or monosaccharide loses biologic activity, the curative effect composition that causes Concha Haliotidis Central Plains to have is ineffective.The up-to-date material chemical composition that studies show that Concha Haliotidis (abalone shell) top layer obviously is different from internal layer, and materials such as more Mg and phycobilin are contained on the top layer, and internal layer then nacre albumen and chitosan is more.Therefore, when different health cares or therapeutic use, should distinguish to some extent, not distinguish in this regard and also have in the processing of existing Concha Haliotidis, thereby limited the scope of application and the medical effect of Concha Haliotidis as medicine.
Summary of the invention
Technical problem to be solved by this invention just provide a kind of obtain more medicinal ingredient, raw material availability height, process fairly simple produce medicine or health food processing technique with Concha Haliotidis.
In order to solve the problems of the technologies described above, the processing step of producing medicine or health food processing technique with Concha Haliotidis is as follows:
(1) cleaning raw material removes impurity and makes its fully absorb water (it is standby that raw materials size the greater can suitably be broken the back into pieces).
(2) ratio in raw material and water is 1: the ratio of 5-10 adds water, with high heat after the heated and boiled, with slow fire boiling 40-60 minute, leach decoction liquor, the raw material that boiled is added 5 times water again, carry out decocting the second time, twice decoction liquor merges standby, at this moment decoction liquor should be oyster, transparent liquid.
(3) hydrolysis of Concha Haliotidis (abalone shell) can be divided into full abalone shell hydrolysis and layering hydrolysis two classes by the difference of the method for hydrolysis:
1. abalone shell hydrolysis: the Concha Haliotidis that will decoct (abalone shell) is hydrolyzed under 40-80 ℃ with the organic acid soln (the concentration difference that different organic acid is used) of 10-80%, obtains full abalone shell hydrolyzed solution;
2. the layering hydrolysis of Concha Haliotidis (abalone shell), operation is as follows:
The Concha Haliotidis faucal that a. will decoct is placed on a stainless (steel) wire or the plastic plate with holes down;
B. the acid solution of the 5%-60% that constantly prepares to above-mentioned Concha Haliotidis appearance sprinkle from the top is hydrolyzed to Concha Haliotidis shell extexine;
C. be hydrolyzed into when outer surface that Concha Haliotidis is hydrolyzed all presents the color and luster the same with inner surface and stop;
D. the Concha Haliotidis after handle on the top layer cleans more than twice with clear water, and the organic acid soln with 10-80% after draining is hydrolyzed under 40-80 ℃ of temperature.
(4) the Concha Haliotidis organic acid hydrolyzed solution heating and filtering that step (3) is obtained is obtained filtrate.
(5) the filtrate heating that step (4) is obtained is concentrated into Baume degrees 5Be above (hydrolyzed solution of different organic acids concentrates required terminal point Baume degrees difference).
(6) hydrolyzed solution that will be concentrated to certain Baume degrees slowly crystallization under the temperature conditions of room temperature or 20-50 ℃.
(during not regrowth of crystal) separates crystal with centrifugation apparatus when (7) reaching the crystallization terminal point with mother solution, and crystal is carried out dried, can be used as calcium of organic acid and uses.
(8) mother solution of step (7) gained is heated once more concentrated, and repeating step (6) and step (7), mother liquid obtained standby as medicinal liquid.
(9) the Concha Haliotidis hydrolyzed solution mother solution that step (8) is obtained, functional requirement according to the various medicinal liquids that will prepare or health food base material, add to according to a certain percentage respectively in the Concha Haliotidis decoction liquor of step (2) gained and go, become the prepared brand-new Concha Haliotidis of the present invention (abalone shell) traditional Chinese medicine liquid.
(10) the Concha Haliotidis medicinal liquid with step (9) gained is a main component, prescription according to classical Chinese medicine proved recipe or health food, add the extract of other suitable Chinese medicine (as: Fructus Lycii, Semen Cassiae etc.) respectively, can modulate based on the crystalline mother solution mixture after above-mentioned Concha Haliotidis decoction liquor and the hydrolysis, adapt to the medicine or the health food of different crowd demand.
Because having adopted elder generation that the Concha Haliotidis water is decocted extracting, the present invention goes out effective ingredient required in traditional Chinese medicine, (for example top layer and the internal layer with Concha Haliotidis adopts the diverse ways hydrolysis respectively in processing to adopt organic acid that the Concha Haliotidis that decocted is hydrolyzed under specific controlled condition then, and the hydrolysis degree of Concha Haliotidis controlled, to obtain the material of biologically active), at last hydrolyzed solution is carried out condensing crystallizing, isolate mother solution behind the calcium of organic acid again according to different purposes, add to respectively to mix in the Concha Haliotidis decoction liquor and use, thereby this method can make the effective Chinese medicine ingredients in the Concha Haliotidis be able to complete preservation utilization, also made full use of other ingredient in the Concha Haliotidis (for example calcium carbonate wherein can also be changed into calcium of organic acid, use) as the calsium supplement that calcium absorption is utilized that is beneficial to human body; Hydrolysising condition can be hydrolyzed into the active substance that little peptide, aminoacid and oligo-chitosan etc. have health care with carapace albumen in the Concha Haliotidis and chitosan etc. through meticulous control.The medicinal ingredient that Concha Haliotidis obtained after this method processed is many, raw material availability is high, process is fairly simple.Ratio Concha Haliotidis in the past utilizes the easier prescription that is fit to different purposes that is deployed into of mode, to adapt to the requirement of various health care or treatment.Of the present invention from Concha Haliotidis (abalone shell) technology of effective component extracting, the quality of the medicine that can guarantee the advanced of its technology and be obtained, so both can satisfy the demand that people improve physical condition, the garbage abalone shell of abalone culture processing is rationally utilized.
Can further be well understood to the present invention by specific embodiments of the invention given below.But they are not limitation of the invention.
The specific embodiment
(can appropriateness break into pieces greatly by shell through removing outer attachment of shell and cleaning for Concha Haliotidis (abalone shell), but needn't wear into powder) after, add certain density organic acid soln, under certain control temperature (30-60 ℃), carry out chemical reaction, after treating that calcium carbonate fully reacts the calcium of organic acid that generates solubility, regulate the hydrolyzed solution pH value, under the condition of control, carry out crystallization and filtration and isolate the hydrolysis crystallized product, but can obtain shellfish hydrolyzed solution such as Concha Haliotidis that hyoscine or food additive use and can be provided as the calcium of organic acid crystallized product that food additive is used.
Embodiment one:
Behind Concha Haliotidis (Haliotis diversicolor abalone shell) cleaning, add the water of 5 times of weight, used instead after boiling with high heat slow fire boiling 40-60 minute, it is standby that drop goes out decoction liquor.Abalone shell after the decoction adds 5 times of water again to carry out decocting the second time, and the decoction liquor that is obtained and the decoction liquor of upper track merge preserves.The abalone shell concentration that decocts through secondary is that the lactic acid (or citric acid, acetic acid, gluconic acid) of 40-80% is hydrolyzed under 50 to 80 ℃.After question response finishes, regulate the hydrolyzed solution pH value with alkali and reach 4-5.Heat concentratedly subsequently, the Baume degrees that is concentrated into hydrolyzed solution stops heating when reaching 8-12Be, 20-50 ℃ down the insulation Crystallization Separation go out mother solution and calcium lactate (or other calcium of organic acid).Crystallization once more after mother solution continued heating and concentrate.Last isolated mother solution and above-mentioned decoction liquor are mixed the Concha Haliotidis medicinal liquid that can obtain different purposes by different proportion.
Embodiment two:
Behind Concha Haliotidis (Australia dish awabi abalone shell) cleaning, add the water of 10 times of weight, used instead after boiling with high heat slow fire boiling 60-90 minute, it is standby that drop goes out decoction liquor.Abalone shell after the decoction adds 5 times of water again to carry out decocting the second time, and the decoction liquor that is obtained and the decoction liquor of upper track merge preserves.To put down through the abalone shell faucal that secondary decocts, from the top sprinkle, wash away after the abalone shell entry material is hydrolyzed with 6% dilute hydrochloric acid.Being hydrolyzed into the abalone shell surface exposes till the nacre fully.It is that the citric acid of 10-20% is hydrolyzed under 30 to 60 ℃ that abalone shell appropriateness after this is handled is broken into pieces with concentration.Treat to heat after the abalone shell complete reaction concentrated, the Baume degrees that is concentrated into hydrolyzed solution stops heating when reaching 5-6Be, 20-50 ℃ down the insulation Crystallization Separation go out mother solution and calcium citrate.Mother solution is mixed the Concha Haliotidis medicinal liquid that can obtain new purposes with above-mentioned decoction liquor.
Comparing embodiment two:
The process of this embodiment is identical with embodiment one, is when the abalone shell after decocting is hydrolyzed, the abalone shell that the lactic acid of employing 60% is put down from top sprinkle faucal.
In embodiment one and embodiment two, hydrolyzate carries out after the Crystallization Separation processing, and the mother solution after the crystallization will determine whether carry out the crystallization treatment second time according to circumstances.Last crystalline mother solution and decoction liquor can be used as the raw material important component part with health-care effect or medical effect of producing other health food or medicine together.Crystal can be used as the raw material of producing calcium supplement health care product.Concha Haliotidis top layer hydrolysate can be used for extracting important biochemical druies such as phycobilin.
Embodiment three:
Behind Concha Haliotidis (haliotis discus hannai Ino abalone shell) cleaning, add the water of 10 times of weight, use instead after boiling with high heat after slow fire boiling 40-60 minute (being decocted first), add other required Chinese crude drug and an amount of water (to flood medical material degree of being) and decoct in the lump.After boiling 40 minutes, the medicinal liquid that drop goes out to decoct is standby.The abalone shell that decocted is taken out clean breaking into pieces, is that the acetic acid of 30-50% is hydrolyzed under 40 to 60 ℃ with concentration.After question response finishes, regulate the hydrolyzed solution pH value with alkali and reach 5-6.Heat concentratedly subsequently, the Baume degrees that is concentrated into hydrolyzed solution stops heating when reaching 10-15Be, 20-50 ℃ down the insulation Crystallization Separation go out mother solution and calcium acetate.With mother solution and above-mentioned decoction liquor, mix the Concha Haliotidis medicinal liquid that can obtain different purposes by different proportion.
Embodiment four:
Behind Concha Haliotidis (Haliotis diversicolor abalone shell) cleaning, add the water of 5 times of weight, used instead after boiling with high heat slow fire boiling 40-60 minute, it is standby that drop goes out decoction liquor.Abalone shell after the decoction adds 5 times of water again to carry out decocting the second time, and the decoction liquor that is obtained and the decoction liquor of upper track merge preserves.The abalone shell concentration that decocts through secondary is the gluconic acid of 30-50%, is hydrolyzed under 40 to 60 ℃.Question response filters after finishing.Filtrate heating is concentrated, and the Baume degrees that is concentrated into hydrolyzed solution stops heating when reaching 15-20Be.Hydrolyzed solution mixed with above-mentioned decoction liquor can obtain the higher Concha Haliotidis medicinal liquid of calcium content.
Claims (5)
1, a kind ofly produce medicine or health food processing technique with Concha Haliotidis, it is characterized in that: described processing technique step is,
(1) clean the Concha Haliotidis raw material, remove impurity and it fully absorbed water;
(2) ratio in Concha Haliotidis raw material and water is 1: the ratio of 5-10 adds water, and after the heated and boiled, reuse slow fire boiling 40-60 minute leaches decoction liquor for the first time with high heat;
Concha Haliotidis organic acid hydrolyzed solution is obtained in the Concha Haliotidis hydrolysis that (3) will decoct;
(4) the Concha Haliotidis organic acid hydrolyzed solution heating and filtering that step (3) is obtained is obtained filtrate;
(5) the filtrate heating that step (4) is obtained is concentrated into more than the Baume degrees 5Be;
(6) hydrolyzed solution that will be concentrated to certain Baume degrees slowly crystallization under the temperature conditions of room temperature or 20-50 ℃;
When (7) reaching the crystallization terminal point, crystal is separated with Concha Haliotidis hydrolyzed solution mother solution;
(8) the Concha Haliotidis hydrolyzed solution mother solution that step (7) is obtained adds in the Concha Haliotidis decoction liquor of step (2) gained and goes, and makes the base material of Concha Haliotidis traditional Chinese medicine liquid or health food.
2, according to claim 1ly produce medicine or health food processing technique with Concha Haliotidis, it is characterized in that: comprise that further the Concha Haliotidis raw material that described step (2) was boiled adds the water more than 5 times again, carry out decocting the second time, first and second decoction liquor of the Concha Haliotidis that twice decoction obtained merge standby again;
3, according to claim 1ly produce medicine or health food processing technique with Concha Haliotidis, it is characterized in that: comprise that further the Concha Haliotidis hydrolyzed solution mother solution with described step (7) gained heats concentrated once more, and repeating said steps (6) and described step (7), mother liquid obtained standby as medicinal liquid;
4, produce medicine or health food processing technique according to claim 1 is described with Concha Haliotidis, it is characterized in that: wherein the described Concha Haliotidis hydrolyzing process of step (3) is, with the Concha Haliotidis that the decocted organic acid soln with 10-80%, 30-80 ℃ of following hydrolysis.
5, claim 1 is described produces medicine or health food processing technique with Concha Haliotidis, and it is characterized in that: wherein the described Concha Haliotidis hydrolyzing process of step (3) is,
(1) the Concha Haliotidis shell extexine of the cleaning acid solution hydrolysis of the 5%-60% for preparing;
(2) be hydrolyzed into when outer surface that Concha Haliotidis is hydrolyzed all presents the color and luster the same with inner surface and stop;
(3) Concha Haliotidis after handle on the top layer cleans with clear water, and the organic acid soln with 10-80% after draining is hydrolyzed under 40-80 ℃ of temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011271612A CN1227014C (en) | 2001-08-27 | 2001-08-27 | Process for producing medicine or health-care food from abalone shells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011271612A CN1227014C (en) | 2001-08-27 | 2001-08-27 | Process for producing medicine or health-care food from abalone shells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1406599A true CN1406599A (en) | 2003-04-02 |
| CN1227014C CN1227014C (en) | 2005-11-16 |
Family
ID=4667149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011271612A Expired - Fee Related CN1227014C (en) | 2001-08-27 | 2001-08-27 | Process for producing medicine or health-care food from abalone shells |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1227014C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101717590B (en) * | 2009-12-23 | 2012-08-29 | 福州大学 | Extraction method of blue-green pigments of abalone shell |
| CN103800483A (en) * | 2014-02-26 | 2014-05-21 | 天津中新药业集团股份有限公司达仁堂制药厂 | Method for preparing traditional Chinese medicinal extract capable of diminishing edema, removing toxicity, purging and stopping bleeding |
| CN103980111A (en) * | 2014-05-23 | 2014-08-13 | 福州大学 | Abalone shell source calcium citrate malate and preparation method thereof |
| CN104016854A (en) * | 2014-05-16 | 2014-09-03 | 福州大学 | Calcium citrate prepared from abalone shell as raw material and preparation method of calcium citrate |
-
2001
- 2001-08-27 CN CNB011271612A patent/CN1227014C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101717590B (en) * | 2009-12-23 | 2012-08-29 | 福州大学 | Extraction method of blue-green pigments of abalone shell |
| CN103800483A (en) * | 2014-02-26 | 2014-05-21 | 天津中新药业集团股份有限公司达仁堂制药厂 | Method for preparing traditional Chinese medicinal extract capable of diminishing edema, removing toxicity, purging and stopping bleeding |
| CN104016854A (en) * | 2014-05-16 | 2014-09-03 | 福州大学 | Calcium citrate prepared from abalone shell as raw material and preparation method of calcium citrate |
| CN104016854B (en) * | 2014-05-16 | 2016-06-01 | 福州大学 | A kind of take abalone shells as the citrate of lime prepared of raw material and method |
| CN103980111A (en) * | 2014-05-23 | 2014-08-13 | 福州大学 | Abalone shell source calcium citrate malate and preparation method thereof |
| CN103980111B (en) * | 2014-05-23 | 2016-06-01 | 福州大学 | Bao shell source calcium citrate malate and its preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1227014C (en) | 2005-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101711591B (en) | Preparation method of fish cartilage extracts and obtained product | |
| CN1227014C (en) | Process for producing medicine or health-care food from abalone shells | |
| CN107495357A (en) | The preparation method and product of abalone shells water-soluble extractive and the shell of seaear | |
| CN102166019A (en) | Method for preparing biological active calcium by using abalone shells | |
| CN101100689A (en) | Method for preparing pearl active peptide | |
| CN102119739B (en) | Formula of astragalus, lucid ganoderma, Chinese wolfberry and peanut milk for protecting liver and preparation method thereof | |
| CN109770353A (en) | Deep-sea fish oil soft capsules and preparation method thereof | |
| KR101708167B1 (en) | Food compositions containing hydrolysis raw materials of red ginseng and sea cucumber and methods for producing the same | |
| CN100571542C (en) | The preparation method of venison enzymolysis oral liquid | |
| CN101850007A (en) | Improvement on hydrolysis process for insoluble animal ingredient in Qingkailing | |
| CN1247718A (en) | Gingko juice and its production process | |
| CN106107966A (en) | Improving eyesight ferment and preparation method thereof | |
| CN1415222A (en) | Cream candy for improving eyesight and its preparation method | |
| JP5395997B2 (en) | Bamboo salt containing bamboo extract derived from Sosetsu bamboo and method for producing the same | |
| CN105030633A (en) | Skin care cream production method and skin care cream | |
| CN103285040A (en) | Method for preparing nano periplaneta americana | |
| CN1256108C (en) | Ass-hide glue phosphotipid composition and its preparing method | |
| CN107467465A (en) | Collagen compound prepared by deep-sea fish fish-bone and fish scale | |
| CN1325063C (en) | L-amino acid water-soluble pearl powder and its preparing method | |
| CN105902614A (en) | A plant salt containing baicalin and a preparing method thereof | |
| CN1048402C (en) | Method for extracting pearl liquid from pearl shell | |
| CN102119734B (en) | Formulation and preparation method of radish seed-containing peanut milk capable of preventing obesity | |
| CN1194631C (en) | Garlic healthy food and preparation thereof | |
| CN1128144A (en) | Chicken embryo extract oral liquid | |
| CN1943598A (en) | Eye medicine for preventing and curing shortsightedness and relieving sight fatigue and its preparing method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |