CN1393259A - Prescription and preparing process of Chinese patent medicine for preventing and treating postoperative adhesion - Google Patents
Prescription and preparing process of Chinese patent medicine for preventing and treating postoperative adhesion Download PDFInfo
- Publication number
- CN1393259A CN1393259A CN 01129666 CN01129666A CN1393259A CN 1393259 A CN1393259 A CN 1393259A CN 01129666 CN01129666 CN 01129666 CN 01129666 A CN01129666 A CN 01129666A CN 1393259 A CN1393259 A CN 1393259A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- tissue adhesion
- content
- radix
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine for preventing and treating the postoperative adhesion is prepared form 4 Chinese medicinal materials including astragalus root, red sage root, bitter orange and rhubarb through aqueous extraction and alcohol deposition.
Description
The present invention relates to a kind of prescriptions of Chinese medicine that is used to prevent and treat tissue adhesion and be prepared into the method for Chinese patent medicine and it is oral, external and injection dosage form with it.
Tissue adhesion is an operation back common complication, and sickness rate is the main cause of abdominal part chronic pain up to 40%, and severe patient also can cause adhesive ileus (sickness rate is up to 9.7%), belongs to common clinical and prevents and treats one of difficult point.At present domestic still do not have specially at the medicine of preventing and treating peritoneal adhesion.Therefore, develop this type of medicine and not only academicly filling up clinical safety, effectively preventing and treating the Chinese patent medicine medication blank of tissue adhesion, what have more practical significance is to have very vast market prospect, will bring abundant economic benefit.
At present, the control of postoperative peritoneal adhesion is mainly set about from the following aspects both at home and abroad:
1. reduce tissue injury: soft operation, careful hemostasis, lavation fully is anti-
It is residual etc. to control foreign body.Not enough: tissue injury is inevitable.
2. prevent the local organization ischemia: intraperitoneal procaine blood vessel dilating, compound recipe pellet
Ginseng injection microcirculation improvement prevents tissue ischemia.
Not enough: zest is big, brings the chance of infection.
3. prevent fiber laydown: corticosteroid and nonsteroidal and-inflammatory drug should
With, somatostatin class thing, the gentle kallikrein inhibitor of blood plasma enzyme etc.
Not enough: immunosuppressant influences wound healing etc.
4. promotion fibrolysis: recombinant tissue plasminogen activator etc.
Not enough: effective dose influences wound healing, and extractive technique is limited, costs an arm and a leg.
5. serosa surface is isolated: medicine barrier such as full-bodied solution or hydrogel etc.Machine
Tool barrier such as Fibrin Glue etc.
Not enough: the sterile working requires high, easily brings infection.
6. Chinese medicine: the application of Chinese medicines such as Xiao Chengqi Tang, DACHENGQI TANG, blood circulation promoting and blood stasis dispelling.
Not enough: mainly be hospital preparation, the amorphous products listing.
The object of the present invention is to provide a kind of super quality and competitive price, effectively Chinese medicine three kind new medicines of prevention of postoperative adhesion.
Prescription component of the present invention and content (percentage by weight) are as follows: QI invigorating class Chinese medicine 20-30%, the class of invigorating blood circulation Chinese medicine 25-35%, the class of regulating the flow of vital energy Chinese medicine 15-25%, rush down lower class Chinese medicine 10-20%.
QI invigorating class Chinese medicine is with Radix Astragali the best in the said components, and content is the best with 27%.The class of invigorating blood circulation Chinese medicine is with Radix Salviae Miltiorrhizae the best, and content is the best with 28%, and the class of regulating the flow of vital energy Chinese medicine is with Fructus Aurantii the best, and content is the best with 12%, rushes down lower class Chinese medicine with Radix Et Rhizoma Rhei the best, and content is the best with 12%.
The present invention manufactures the method for tissue adhesion preparation with above-mentioned prescription, it is characterized in that technical process is as follows: (1), extract: by above-mentioned prescription each component is fed intake in proportion, decocting boils three times, merges decocting liquid, is concentrated into every milliliter of medicinal liquid and contains crude drug 1-2g.(2), refining: gradient incremental method precipitate with ethanol, cold preservation separates and removes precipitation.(3), semi-finished product preparation: reclaim ethanol.It is 1.10-1.3 that adding distil water is adjusted medicinal liquid density.High speed centrifugation is removed precipitation.(4), semi-finished product detect control: measure main component content.(5), make finished product: packing, capping.
The above-mentioned method for preparing the tissue adhesion preparation, gradient incremental method precipitate with ethanol in the step 2, medicinal liquid contain the alcohol amount and reach 50%, 60%, 70% respectively.
The present invention states the method for preparing the tissue adhesion preparation, main component content detection danshensu, Sennoside A in the above-mentioned steps 4.
Below in conjunction with example in detail content of the present invention.
Embodiment: make the method for producing control tissue adhesion medicine and describe in detail:
At first, getting the commercially available Radix Astragali, Radix Salviae Miltiorrhizae, Fructus Aurantii decoction pieces is that raw material feeds intake by a certain percentage, adding 3,2 times of water gagings respectively extracts in multi-function extractor twice, extraction time is respectively 1.5h, 1h, decoct for the second time and add Radix Et Rhizoma Rhei after 30 minutes and decocted 30 minutes, merging filtrate is concentrated into every milliliter of medicinal liquid and contains crude drug 1-2g, adding 95% ethanol makes medicinal liquid contain the alcohol amount to reach 50%, filter and remove precipitation.Supernatant adds 95% ethanol to be made medicinal liquid contain the alcohol amount to reach 60%, filter and remove precipitation.Supernatant adds 95% ethanol to be made medicinal liquid contain the alcohol amount to reach 70%, filter and remove precipitation.Reclaim ethanol.It is 1.10-1.30 that the medicinal liquid adding distil water is regulated medicinal liquid density, cold preservation, and high speed centrifugation is removed precipitation, packing.
Claims (13)
1, a kind of Chinese medicine compound prescription that is used to prevent and treat tissue adhesion is characterized in that component and content (percentage by weight) are as follows: QI invigorating class Chinese medicine 20-30%, the class of invigorating blood circulation Chinese medicine 25-35%, the class of regulating the flow of vital energy Chinese medicine 15-25%, rush down lower class Chinese medicine 10-20%.
2, a kind of Chinese medicine compound prescription that is used to prevent and treat tissue adhesion, it is characterized in that component and content (percentage by weight) are as follows: QI invigorating class Chinese medicine 20-30% comprises Radix Ginseng, Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae.
3, a kind of Chinese medicine compound prescription that is used to prevent and treat tissue adhesion, it is characterized in that component and content (percentage by weight) are as follows: the class of invigorating blood circulation Chinese medicine 25-35% comprises Radix Salviae Miltiorrhizae, Semen Persicae, Flos Carthami, Hirudo, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, rhizoma sparganic, Rhizoma Curcumae.
4, a kind of Chinese medicine compound prescription that is used to prevent and treat tissue adhesion, it is characterized in that component and content (percentage by weight) are as follows: the class of regulating the flow of vital energy Chinese medicine 15-25% comprises the Radix Aucklandiae, Fructus Aurantii Immaturus, Fructus Aurantii, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Fructus Amomi, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi, Radix Bupleuri.
5, a kind of Chinese medicine compound prescription that is used to prevent and treat tissue adhesion is characterized in that component and content (percentage by weight) are as follows: rush down lower class Chinese medicine 10-20%, comprise Radix Et Rhizoma Rhei, Folium Sennae, Natrii Sulfas, Fructus Crotonis.
6, be used to prevent and treat the Chinese medicine compound prescription of tissue adhesion according to claim 2, it is characterized in that component QI invigorating class Chinese medicine is the Radix Astragali, content is preferred range with 23-27%.
7, be used to prevent and treat the Chinese medicine compound prescription of tissue adhesion according to claim 3, it is characterized in that the component class Chinese medicine of invigorating blood circulation is Radix Salviae Miltiorrhizae, content is preferred range with 23-27%.
8, be used to prevent and treat the Chinese medicine compound prescription of tissue adhesion according to claim 4, it is characterized in that the component class Chinese medicine of regulating the flow of vital energy is Fructus Aurantii, content is preferred range with 7-12%.
9, be used to prevent and treat the Chinese medicine compound prescription of tissue adhesion according to claim 5, it is characterized in that it is Radix Et Rhizoma Rhei that component is rushed down lower class Chinese medicine, content is preferred range with 7-12%.
10, manufacture the method for tissue adhesion preparation with above-mentioned prescription, it is characterized in that technical process is as follows: (1), extraction: each component is fed intake in proportion by above-mentioned prescription, decocting boils two times, Radix Et Rhizoma Rhei adds after decocting 30 minutes for the second time, merge decocting liquid, be concentrated into every milliliter of medicinal liquid and contain crude drug 1-2g.(2), refining: gradient incremental method precipitate with ethanol, cold preservation separates and removes precipitation.(3), semi-finished product preparation: reclaim ethanol.It is 1.10-1.3 that adding distil water is adjusted medicinal liquid density.High speed centrifugation is removed precipitation.(4), semi-finished product detect control: measure main component content.(5), make finished product: embedding, sterilization.
11, according to the described method for preparing the tissue adhesion preparation of claim 10, it is characterized in that gradient incremental method precipitate with ethanol in the above-mentioned steps 2, medicinal liquid contains the alcohol amount and reaches 50%, 60%, 70% respectively.
12,, it is characterized in that main component content detection danshensu, Sennoside A in the above-mentioned steps 4 according to the described method for preparing the tissue adhesion preparation of claim 10.
13, manufacture the dosage form of tissue adhesion preparation with above-mentioned prescription, it is characterized in that oral, external and injection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01129666 CN1393259A (en) | 2001-06-26 | 2001-06-26 | Prescription and preparing process of Chinese patent medicine for preventing and treating postoperative adhesion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01129666 CN1393259A (en) | 2001-06-26 | 2001-06-26 | Prescription and preparing process of Chinese patent medicine for preventing and treating postoperative adhesion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1393259A true CN1393259A (en) | 2003-01-29 |
Family
ID=4669350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01129666 Pending CN1393259A (en) | 2001-06-26 | 2001-06-26 | Prescription and preparing process of Chinese patent medicine for preventing and treating postoperative adhesion |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1393259A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766789A (en) * | 2010-04-08 | 2010-07-07 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composite for treating appendicitis and preparation method thereof |
| CN101450149B (en) * | 2008-12-29 | 2010-12-22 | 黑颖睿 | Medicine for treating abdominal postoperative stomach palsy syndrome and preparation method |
| CN104491381A (en) * | 2014-11-24 | 2015-04-08 | 周广生 | Traditional Chinese medicinal composition for treating adhesive intestinal obstruction |
| CN111035699A (en) * | 2020-01-13 | 2020-04-21 | 叶关毅 | Research method for promoting gastrointestinal function recovery after abdominal operation by using traditional Chinese medicine formula granule anal drip |
-
2001
- 2001-06-26 CN CN 01129666 patent/CN1393259A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450149B (en) * | 2008-12-29 | 2010-12-22 | 黑颖睿 | Medicine for treating abdominal postoperative stomach palsy syndrome and preparation method |
| CN101766789A (en) * | 2010-04-08 | 2010-07-07 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composite for treating appendicitis and preparation method thereof |
| CN101766789B (en) * | 2010-04-08 | 2011-04-27 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composite for treating appendicitis and preparation method thereof |
| CN104491381A (en) * | 2014-11-24 | 2015-04-08 | 周广生 | Traditional Chinese medicinal composition for treating adhesive intestinal obstruction |
| CN111035699A (en) * | 2020-01-13 | 2020-04-21 | 叶关毅 | Research method for promoting gastrointestinal function recovery after abdominal operation by using traditional Chinese medicine formula granule anal drip |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1085080A (en) | A kind of medicated wine | |
| CN1224614A (en) | Medicine for preventing and curing cardiac and cerebral vascular diseases and its preparation | |
| CN1840126A (en) | Chinese medicine for treating amblyopia and myopia | |
| CN1291745C (en) | Chinese medicinal composition for diseases of nervus, varscular headache, cerebral blood supply lack and sequel of apolexy | |
| CN101028481A (en) | Medicinal liquor for treating hyperosteogeny and lumbar intervertebral disc protrusion | |
| CN1457831A (en) | Dynamic medicine for channels and collaterals and blood vessel | |
| CN104324355A (en) | Traditional Chinese medicine composition for treating peripheral neuropathy caused by diabetes | |
| CN1739611A (en) | Stasis relieving oral liquid for treating rhinitis and its prepn | |
| CN1103223C (en) | Chinese medicine for treating cholecystitis | |
| CN1393259A (en) | Prescription and preparing process of Chinese patent medicine for preventing and treating postoperative adhesion | |
| CN1057230C (en) | Traditional Chinese medicine capsule for treating thrombophlebitis | |
| CN1413683A (en) | Medicine for treating gynecopathy | |
| CN1141138C (en) | Medicine composition for curing coronary heart disease | |
| CN1101199C (en) | Chinese-medicinal capsule for treating hyperlipomia | |
| CN101549057A (en) | Chinese medicine composition for curing hyperlipemia, cerebral arteriosclerosis and ischemic apoplexy and method of preparing the same | |
| CN1589839A (en) | Stasis transforming pain relieving particle agent and its preparation method | |
| CN1059120C (en) | Chinese medicine for treating bone wound | |
| CN1077127A (en) | Incense circuit health magic liquid and preparation technology thereof | |
| CN1406617A (en) | Tablets against allergic purpura | |
| CN1279995A (en) | Chinese medicine composition for curing rhinitis | |
| CN1192916A (en) | Chinese medicine for treatment of gout | |
| CN101579458A (en) | Traditional Chinese medicine for treating infant susceptibility | |
| CN102225132A (en) | Traditional Chinese medicine compound for treating hyperlipidaemia, cerebral arteriosclerosis and ischemic stroke and preparation method thereof | |
| CN1080570C (en) | Medicinal liquor for treating psoriasis and preparation method thereof | |
| CN1907419A (en) | Decoction preparation for treating xuezaoshengfeng type skin eczema and its preparation process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |