CN1377696A - Chinese herbal medicine preparation for curing viral hepatitis and its preapring method - Google Patents

Abstract

The Chinese herbal medicine preparation is granule prepared with capillary artemisia, negundo chastetree root, plantain, Indian kalimeris herb, glabrousleaf pittosporum root and other six kinds of Chinese medicinal materials and through decoction, concentration, filtering, drying, pelletizing and packing. It is used to treat viral hepatitis and has reliable curative effect, no toxic side effect and low cost.

Description

A kind of Chinese herbal and crude drugs preparations for the treatment of viral hepatitis and preparation method thereof

Technical field is a kind of treats medicine that viral hepatitis uses and preparation method thereof, belongs to field of Chinese herbal.

The technical background modern medicine is thought: viral hepatitis is the higher infectious disease of a kind of sickness rate that is caused by multiple hepatitis virus, and be divided into first, second, third, fourth, the eleventh of the twelve Earthly Branches five types, all with loss of appetite, weakly feel sick, hepatomegaly and liver function injury be its feature, be that HAN is in the intestinal intrusive body, enter blood, form viremia, in hepatocyte, duplicate, easily cause hepatocellular damage.Acute fatal hepatitis, then jaundice is deepened rapidly, and liver dwindles rapidly, and bleeding tendency is arranged, and ascites, liver is smelly and acute renal failure, and with nervous symptoms.Hepatitis B be virus in hepatocyte by a series of immunoreation, liver is got involved, it is mostly slow fall ill, but treats relatively more difficult.

The method of western medical treatment viral hepatitis is at present: (1) isolates; (2) lie up; (3) with the hepatic treatment, for example use V _B, V _C, V _K4, inosine, glucuronolatone, hepatocyte growth factor etc.; (4) use antiviral drugs such as interferon, polyinosini treatment; (5) with immunoregulation medicament treatment, for example thymosin, transfer factor, polyporusum bellatus etc.Not only the course of treatment is long and trouble, medical expense costliness for the western medicine and medical practitioners method, and cure rate is not high, and easily recurrence can not be effected a radical cure viral hepatitis.

Summary of the invention the present invention combines hereditary recipe with the modern pharmaceutical technology, preparation of a sharp treatment viral hepatitis and preparation method thereof is provided, and accomplishes to eliminate rapidly hepatitis virus, makes the patient produce antibody mediated immunity power, does not recur the radical cure viral hepatitis.

The percentage by weight of the present invention's prescription is:

Herba Artemisiae Scopariae 9-12 Radix viticis negundo 9-12

Herba Plantaginis 7-10 Herba Kalimeridis 7-10

Fructus Gardeniae root 12-16 Fructus Gardeniae 9-12

Radix Gentianae 4-8 Ramulus Salicis Babylonicae 9-12

Rhizoma Seu Herba Pteridis Dactylinae 7-10 Radix Serissae 9-12

Herba Eleusines Indicae 9-12

Preparation method is at first the herbal raw material of cleaned section to be equipped with by above-mentioned prescription, will be equipped with then good raw material through decoct, concentrate, filtered and recycled, drying, granulation process, be packaged into bag after the oven dry, make electuary.Therapeutic Method is to obey electuary hepatitis A patient day three times, and each 20mg takes after mixing it with hot water; To serious symptom type hepatitis, hepatitis B, liver cirrhosis, hepatic ascites patient, can suitably increase the weight of dosage according to physical condition.

Viral hepatitis belongs to the category of Chinese medicine " jaundice ", " costalgia ", " gathering ".The traditional Chinese medical science is thought: viral hepatitis is that the epidemic disease caused by damp-heat pathogen poison is invaded liver and gall, cause suffocating of liver and gall not normal, bile is excessive, it is burnt during damp hinders, influence the taste lifting, causing the fortuneization functional disorder, form phlegm retention and ascites, is the aim for the treatment of primary disease so enzyme falls in clearing away heat-damp and promoting diuresis, dispersing the stagnated liver-QI for regulating the stomach, invigorating the spleen for dissipating phlegm, removing heat from blood jaundice eliminating, detoxifcation.

Treatment principle of the present invention derives from above-mentioned theory of Chinese medical science.The pharmacological action of each component is the effect that Herba Artemisiae Scopariae, Herba Plantaginis have clearing away heat-damp and promoting diuresis detoxifcation jaundice eliminating in the prescription; Herba Eleusines Indicae, Fructus Gardeniae, Rhizoma Seu Herba Pteridis Dactylinae have the merit of heat-clearing and toxic substances removing jaundice eliminating; Fructus Gardeniae root energy removing heat from blood jaundice eliminating, heat-clearing and toxic substances removing; Herba Kalimeridis can the heat clearing away spleen invigorating go to amass; Radix Serissae energy clearing away heat-damp and promoting diuresis soothing liver-QI for relieving depression; Radix viticis negundo has the stomach function regulating damp eliminating effect of reducing phlegm; Radix Gentianae can be held up liver to fall enzyme, fall wadding.Each medicine share then clearing away heat-damp and promoting diuresis, detoxifcation falls that enzyme, dispersing the stagnated liver-QI for regulating the stomach, spleen invigorating eliminate the phlegm, the effect of removing heat from blood jaundice eliminating, Cure Viruses hepatitis effectively.

Compared with prior art, the present invention has following characteristics:

1, the medicine source is extensive, the medicine valency is cheap, helps the treatment of rural area and poverty-stricken area hepatitis.

2, curative effect is reliable, has no side effect short treating period.Can cure fully in general five days hepatitis A; Hepatitis gravis, hepatitis B, liver cirrhosis, hepatic ascites also there is remarkable therapeutic effect.

3, processing technique is simple, patient's taking convenience.

4, can effect a radical cure viral hepatitis, especially hepatitis A be had specially good effect.After patient's recovery from illness,, can not recur again owing to produce antibody mediated immunity power.

Specific embodiment embodiment one

At first be equipped with by the percentage by weight of following prescription herbal raw material with cleaned section:

Herba Artemisiae Scopariae 12 Radix viticis negundos 9 Herba Plantaginiss 10

Herba Kalimeridis 7 Fructus Gardeniae 9 Fructus Gardeniae roots 16

Ramulus Salicis Babylonicae 12 Radix Gentianae 8 Rhizoma Seu Herba Pteridis Dactylinae 10

Radix Serissae 9 Herba Eleusines Indicae 12

To be equipped with then good raw material through decoct, concentrate, filtered and recycled, drying, granulation process, be packaged into bag after the oven dry, make electuary.

Embodiment two

Preparation method is identical with embodiment one, and just the change of the percentage by weight of prescription is as follows:

Herba Artemisiae Scopariae 9 Radix viticis negundos 12 Herba Plantaginiss 7

Herba Kalimeridis 10 Fructus Gardeniae 12 Fructus Gardeniae roots 12

Ramulus Salicis Babylonicae 9 Radix Gentianae 4 Rhizoma Seu Herba Pteridis Dactylinae 7

Radix Serissae 12 Herba Eleusines Indicae 9

Embodiment three

Preparation method is identical with embodiment one, and just the change of the percentage by weight of prescription is as follows:

Herba Artemisiae Scopariae 10 Radix viticis negundos 10 Herba Plantaginiss 7.5

Herba Kalimeridis 7.5 Fructus Gardeniae 7.5 Fructus Gardeniae roots 15

Ramulus Salicis Babylonicae 10 Radix Gentianae 5 Rhizoma Seu Herba Pteridis Dactylinae 7.5

Radix Serissae 10 Herba Eleusines Indicae 10

Embodiment four

Preparation method is identical with embodiment one, and just the change of the percentage by weight of prescription is as follows:

Herba Artemisiae Scopariae 9.7 Radix viticis negundos 9.7 Herba Plantaginiss 8

Herba Kalimeridis 8 Fructus Gardeniae 8 Fructus Gardeniae roots 13

Ramulus Salicis Babylonicae 9 Radix Gentianae 6.5 Rhizoma Seu Herba Pteridis Dactylinae 8

Radix Serissae 9.7 Herba Eleusines Indicae 9.7

Clinical observation report

One, selects the standard of case

Treatment is organized in 220 examples, male's 140 examples, women's 80 examples, age 14-40 one full year of life, average 28.8 one full year of life; Matched group 90 examples, male's 56 examples, women's 34 examples, age 18-45 one full year of life, average 29.4 one full year of life.Two groups of patients all are Hepatitis A through the chemical examination of counties and cities' level the People's Hospital, and two groups of patients have comparability at aspect there was no significant differences (P＞0.05) such as age, sex, the state of an illness and the courses of disease.

Two, diagnostic criteria

Draft with reference to the diagnostic criteria of nineteen ninety Shanghai whole nation viral hepatitis academic conference revision and the viral hepatitis treatment scheme (try) of the 5th the national infectious disease parasitic disease academic conference revision in Beijing in May nineteen ninety-five, icteric index is higher, costalgia, asthenia, weak, vomit, detest oil, yellow urine is lacked.Jaundice appears in sclera, skin, and the transaminase raises.

Three, therapeutic scheme design

1, treatment group: use the invention prescription, with Herba Artemisiae Scopariae 20g (10%), Radix viticis negundo 20g (10%), Herba Plantaginis 15g (7.5%), Herba Kalimeridis 15g (7.5%), Fructus Gardeniae root 30g (15%), Fructus Gardeniae 15g (7.5%), Radix Gentianae 10g (5%), Ramulus Salicis Babylonicae 20g (10%), Rhizoma Seu Herba Pteridis Dactylinae 15g (7.5%), Radix Serissae 20g (10%), Herba Eleusines Indicae 20g (10%) juice at a simmer, 1 dose of every day, divide clothes three times, logotype five days.

2, matched group: use quiet of this Yinzhihuang Injection, Vitc2g, inosine 0.8g, oral compound vitamin B, logotype five days.

Four, efficacy assessment standard

Viral hepatitis treatment scheme (trying) with reference to the academic session discussing revision of nineteen ninety-five whole nation infectious disease parasite is drafted.Produce effects: clinical symptom disappearance, liver function and icteric index inspection recover normal.Effectively: cardinal symptom disappears, and liver function test recovers normal or mile abnormality, and icteric index is near normal.Invalid: cardinal symptom does not take a turn for the better, and liver function does not have improvement.

Five, therapeutic outcome (the gained data are summarized) is as follows:

Group	????n	Produce effects (%)	Effectively (%)	Invalid (%)	Total effective rate
						The treatment group	????220	?204(92.8％)	??12(5.4％)	??4(1.8％)	????98.2％
Matched group	????90	?42(46.7％)	??20(22.2％)	??28(31.1％)	????68.9％

Annotate: compare P＜0.01 with matched group.

Claims (2)

1, a kind of Chinese herbal and crude drugs preparations for the treatment of viral hepatitis is characterized in that the percentage by weight of each component prescription is:

Herba Artemisiae Scopariae 9-12 Radix viticis negundo 9-12

Herba Plantaginis 7-10 Herba Kalimeridis 7-10

Fructus Gardeniae root 12-16 Fructus Gardeniae 9-12

Radix Gentianae 4-8 Ramulus Salicis Babylonicae 9-12

Rhizoma Seu Herba Pteridis Dactylinae 7-10 Radix Serissae 9-12

Herba Eleusines Indicae 9-12

2, a kind of preparation method for the treatment of the viral hepatitis Chinese herbal and crude drugs preparations, its step are at first to be equipped with by the percentage by weight of the following prescription herbal raw material with cleaned section:

Herba Artemisiae Scopariae 9-12 Radix viticis negundo 9-12

Herba Plantaginis 7-10 Herba Kalimeridis 7-10

Fructus Gardeniae root 12-16 Fructus Gardeniae 9-12

Radix Gentianae 4-8 Ramulus Salicis Babylonicae 9-12

Rhizoma Seu Herba Pteridis Dactylinae 7-10 Radix Serissae 9-12

Herba Eleusines Indicae 9-12

To be equipped with then good raw material through decoct, concentrate, filtered and recycled, drying, granulation process, be packaged into bag after the oven dry, make electuary.