CN1346671A

CN1346671A - Oral Chinese medicine for treating acute or chronic nasosinusitis

Info

Publication number: CN1346671A
Application number: CN 01136392
Authority: CN
Inventors: 史佩蕾
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-10-12
Filing date: 2001-10-12
Publication date: 2002-05-01

Abstract

An oral Chinese medicine for treating acute or chronic nasosinusitis is prepared from 7 Chinese-medicinal materials including anemarrhena rhizome, phellodendron bark, xanthium fruit, dahurian angelica root, etc. Its advantages are high cure rate, and no recurrence.

Description

Treat the oral Chinese medicine of acute and chronic sinusitis

The present invention relates to a kind of oral Chinese medicine for the treatment of acute and chronic sinusitis, belong to by pure Chinese herbal medicine and refine the Chinese medicine preparation of making.

Sinusitis especially chronic purulent sinusitis is common nose disease, and the traditional Chinese medical science is referred to as " nasal sinusitis ".Suffer from sinusitis person often endure to the fullest extent all the year round the turbid tears of stream more than, have a stuffy nose, have a bad nose, the hardship of feeling of fullness in the head headache.It is reported that only just there are 3,700 ten thousand sinusitis patients in the U.S..Modern study shows that the cause of disease of sinusitis is a courses of infection.Pathogenic bacterium mostly are pyococcus, as Diplococcus pneumoniae, haemolysis type streptococcus, staphylococcus, micrococcus catarrhalis etc.; Secondly be bacillus, as hemophilus influenza, Bacillus proteus, escherichia coli etc.; Morbific anaerobe is quite a few.And the patient falls ill because of the mixed infection of multiple pathogenic bacteria.

The main means of world wide internal therapy sinusitis have medicine for external use (as vasoconstrictor), antibiotic, puncture, operation at present, also have laser, microwave etc., but curative effect (especially treating chronic sinusitis) is all not really desirable, can not reach the effect of radical cure.The more domestic Chinese patent medicine that treatment sinusitis are also arranged, but curative effect is not fully up to expectations equally, and the patient is very easily recurred.

The object of the present invention is to provide and a kind ofly can effect a radical cure this persistent ailment of sinusitis, oral Chinese medicine without any side effects again is to remove the misery of extensive patients.

The basic cause of disease according to sinusitis is that pathogenic bacteria (comprising antibacterial and fungus) infects, and the present invention is sensible with lung qi dispersing, antiinflammatory is the principles of formulating prescriptions except that tears, and used Chinese herbal medicine has following pharmacological action: (1) has inhibitory action to multiple pathomycete; (2) staphylococcus, group B streptococcus etc. there is inhibitory action; (3) have protection nasal mucosa, the absorption that promotes mucosa secretions, the effect that reduces inflammation, can unobstructed nasal cavity.

The present invention refines in the preparation of the ratio in the certain limit with following Chinese herbal medicine and forms: Rhizoma Anemarrhenae 20%-30%, Cortex Phellodendri 20%-30%, Fructus Xanthii 10%-20%, Radix Angelicae Dahuricae 10%-20%, Flos Magnoliae 5%-10%, Radix Aucklandiae 5%-10%, Herba Asari 5%-10%.Its optimal proportion is: the Rhizoma Anemarrhenae 23.08%, Cortex Phellodendri 23.08%, Fructus Xanthii 15.38%, the Radix Angelicae Dahuricae 15.38%, Flos Magnoliae 7.69%, the Radix Aucklandiae 7.69%, Herba Asari 7.69%.

Manufacture method is as described below:

The mixture method for making:

(1) total amount is not less than the 1000 prescription Chinese crude drugs that restrain and adds proper amount of clear water (being as the criterion) immersion 1 hour with energy submergence medical material, at hermetic container (non-high tension unit, just airtight relatively, avoid moisture to evaporate in a large number) in heated and boiled and make it keep little boiling 1 hour, then extracting solution is poured out.In container, add clear water submergence medical material in addition, make it keep little boiling 1 hour after directly boiling again, extracting solution is poured out, then repeat this step and extract once again.Merge 3 times extracting solution, filter standby with 400 order filter clothes.

(2) extracting solution after will filtering is heated to boiling, and moisture is evaporated rapidly, goes out the amount concentrated extracting solution of X milliliter medicinal liquid by X gram medical material, again its placement is cooled to room temperature.Add 95% medical ethanol then, the concentration of alcohol to solution reaches 60%, leaves standstill 12 hours messenger drug liquid precipitates after fully stirring.

(3) medicinal liquid of post precipitation is two-layer about having formed naturally, and the upper strata is a supernatant, and lower floor is a residue.After the supernatant taking-up, again residue is filtered with 400 order filter clothes.With the filtrate and supernatant merging that obtain after filtering, heated and boiled (should consider alcoholic acid recovery during suitability for industrialized production, to reduce cost) transpiring moisture makes medicinal liquid be concentrated into the thick paste shape then, and its proportion is 1.22 with the proportion instrumentation in the time of 90 ℃.

(4) need the ratio of 1 gram antiseptic (ethylparaben) to calculate the consumption of antiseptic in every kilogram of thick paste.Use 5 milliliters of alcoholic acid ratios to be dissolved in 95% the medical ethanol in 1 gram antiseptic antiseptic, treat to add after thick paste is cooled to room temperature.Can pack after stirring.

The granule method for making:

(1) with mixture method for making (1).

(2) with mixture method for making (2).

(3) be that with mixture method for making (3) difference gained thick paste proportion is 1.30.

(4) in thick paste, add an amount of white sugar, be stirred into soft material through pulverizing.Granulate oven dry then.Can pack after the cooling.

The present invention is applied to clinical, and acute and chronic sinusitis is had unique curative effect: generally speaking, can fully recover in 12 days to 60 days, serious symptom is no more than 120 days, does not recur after healing.

Medical record one of is given an example:

The patient: Pan so-and-so, the woman, 7 one full year of life during prescription on individual diagnosis, 21 kilograms of body weight are lived Nanguan District Freedom Road, Changchun.

Medical history and symptom: cat fever in January, 1998, continue a large amount of yellow pus tears of stream, make a definite diagnosis March in the same year and suffer from sinusitis.The state of an illness is controlled behind 3 all antibiotic therapies, and yellow pus tears transfer white sticky tears to, but still has a stuffy nose, sleeps and snore.November in the same year and in November, 2000 increase the weight of because of flu makes sinusitis, and antibiotic control is used in yellow pus tears recurrence equally, but poor effect.Infant flows the glutinous tears of white for a long time, and nasal obstruction is used mouth breathing.

Check and treatment: on November 13rd, 2000 was done the X ray examination in Norman Bethune Medical University, Changchun first Affiliated Hospital.The X report from a liner is accused: " upper left sinus frontalis density enrichment, surplus no abnormality seen." diagnostic result: the left maxillary sinus inflammation.Promptly began to take Chinese medicine preparation treatment of the present invention the same day, the pus tears reduce after 4 days, and fade away; Right BITONG gas after 15 days; Left nose is ventilated substantially after 30 days.December was done the check of X line again on the 17th.The X report from a liner is accused: " two sinus frontalis, maxillary sinus are grown normal, left maxillary sinus bottom density enrichment, and hole wall sclerotin is normal." diagnostic result: the left maxillary sinus inflammation, but with the contrast of the X-ray on November 13, the state of an illness takes an evident turn for the better.December was done the X ray examination for the third time on the 27th.The X report from a liner is accused: " bilateral sinus frontalis, sieve hole, maxillary sinus physically well develop, and the hole chamber is transparent, and the hole wall is smooth, does not see that mucosa thickens and bone destruction." diagnostic result: bilateral nasal sinuses no abnormality seen.So far, infant was taken Chinese patent medicine of the present invention totally 45 days, and nasal obstruction disappears, and the pus tears disappear, and euosmia reaches the clinical cure standard.So far there is not recurrence.

Medical record give an example two:

The patient: Zhang, the man, works in the bath center, Changchun at 29 one full year of life during prescription on individual diagnosis.

Medical history and symptom: the stream turbid nasal discharge reaches 12 years, has the blood streak in the tears sometimes; Nasal obstruction, obstructed when leading to during left nare, right naris is obstructed substantially; Headache; Substantially there is not olfactory sensation; Bitter taste.Took medicines such as BIYANKANG, XINFANG BIYAN JIAONANG, effect is all bad.

Check and treatment: the X report from a liner is accused: " bilateral maxillary sinus consistent in density evenly increases, hole chamber muddiness, and the bone wall shows unclear." diagnostic result: the bilateral maxillary sinusitis.Rose on March 17th, 2000 and take Chinese medicine preparation treatment of the present invention, the 3rd day, the nasal obstruction symptom promptly alleviated to some extent, and left nare is logical; The 5th day, the nasal obstruction symptom was further improved, secretions increase, and color is yellow, but easily blows out than before, illustrates that the pus that stores in sinus cavities has begun to discharge; The 15th day, the nasal obstruction symptom was improved greatly, and right nostril is logical substantially, and the secretions color is white by xanthochromia, and amount obviously reduces; After two months, various symptoms all disappear.The X report from a liner is accused: " bilateral nasal sinuses no abnormality seen." reach the clinical cure standard.So far there is not recurrence.

Claims

1. the oral Chinese medicine of the acute and chronic sinusitis of treatment is characterized in that it is refined in the ratio in certain limit preparation by following Chinese herbal medicine to form (can be made into mixture and granule):

Rhizoma Anemarrhenae 20%-30%, Cortex Phellodendri 20%-30%, Fructus Xanthii 10%-20%, Radix Angelicae Dahuricae 10%-20%, Flos Magnoliae 5%-10%, Radix Aucklandiae 5%-10%, Herba Asari 5%-10%.