CN102670950B

CN102670950B - Chinese medicinal oral liquid for treating cough and preparation method thereof

Info

Publication number: CN102670950B
Application number: CN 201210182094
Authority: CN
Inventors: 黄芸
Original assignee: 黄芸
Current assignee: HANGZHOU HUAWEI PHARMACEUTICAL LLC
Priority date: 2012-06-04
Filing date: 2012-06-04
Publication date: 2013-09-18
Anticipated expiration: 2032-06-04
Also published as: CN102670950A

Abstract

The invention discloses a Chinese medicinal oral liquid for treating cough. The Chinese medicinal oral liquid is prepared from the following Chinese herbal medicines in part by weight: 200 to 400 parts of unibract fritillary bulb, 200 to 400 parts of corsvenor momordica fruit, 200 to 400 parts of mulberry leaf, 100 to 200 parts of pagoda tree flower bud, 100 to 200 parts of radish seed and 10 to 30 parts of liquoric root. The invention is characterized in that the Chinese medicinal oral liquid can cure patients, is quick in response, low in cost and is worthy of clinical popularization and application, and has a good effect and small toxic and side effects; and cough does not relapse.

Description

Treatment cough Chinese medicine oral liquid and preparation method

Technical field

The invention belongs to the field of Chinese medicines, particularly a kind of cough Chinese medicine oral liquid and preparation method for the treatment of.

Background technology

Cough is the protectiveness respiratory reflex action that human body is removed the interior secretions of respiratory tract or foreign body.Though its favourable one side is arranged, violent long-term cough can cause respiratory tract hemorrhage.Correct general cough and the cough variant asthma distinguished prevents mistaken diagnosis.Treatment cough should be distinguished the cough type, Western medicine, Chinese medicine all can, Chinese medicine is used for the treatment of the cough medicine, owing to have little, the eutherapeutic characteristics of side effect, so favored by people.

Summary of the invention

The object of the present invention is to provide little, the good effect of a kind of side effect, be used for the treatment of cough Chinese medicine oral liquid and preparation method.

For achieving the above object, the present invention is achieved by the following technical solutions:

Treatment cough Chinese medicine oral liquid is to be made by the crude drug of following parts by weight:

Bulbus Fritillariae Cirrhosae 200-400 part, Fructus Momordicae 200-400 part, winter folium mori 200-400 part, Flos Sophorae Immaturus 100-200 part, Semen Raphani 100-200 part, Radix Glycyrrhizae 10-30 part.

Described treatment cough Chinese medicine oral liquid is to be made by the crude drug of following parts by weight:

300 parts of Bulbus Fritillariae Cirrhosaes, 300 parts of Fructus Momordicaes, 300 parts of winter folium moris, 150 parts of the Flos Sophorae Immaturus, 150 parts of Semen Raphanis, 20 parts in Radix Glycyrrhizae.

Described treatment cough Chinese medicine oral liquid and preparation method comprise the following steps:

Get 300 parts of crude drug Bulbus Fritillariae Cirrhosaes, 300 parts of Fructus Momordicaes, 300 parts of winter folium moris, 150 parts of the Flos Sophorae Immaturus, 150 parts of Semen Raphanis, 20 parts in Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, and decocts secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, and to contain amount of alcohol be 60% to making to add ethanol, stirs evenly, left standstill 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 10%, refined honey 22%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, namely.

Instructions of taking: the adult measures every day three times, each 10ml.3 days courses for the treatment of, the back of taking medicine is many took effect at 2 days, and cure 1-2 the course for the treatment of, and oral liquid characteristics of the present invention are that the patient is fully recovered, instant effect, and effective, toxic and side effects is little, does not have recurrence, and cost is low, is worth clinical application.

In the selected raw material of Chinese medicine of the present invention, Bulbus Fritillariae Cirrhosae: bitter, cold, return lung, heart channel, heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing, be used for wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore; Fructus Momordicae: cool, sweet, return lung, large intestine channel, clearing heat and moistening lung, cough-relieving, sore-throat relieving, laxation relieving constipation are used for lung-fire cough caused by dryness, pharyngalgia aphonia, dryness of the intestine constipation; Winter folium mori: sweet, bitter, cold, return lung, Liver Channel, dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving; The Flos Sophorae Immaturus: cold, cool, sweet, flat, go into liver, large intestine channel, cooling blood for hemostasis, liver heat removing pathogenic fire reducing; Semen Raphani: hot, sweet, flat, return spleen, stomach, lung meridian, help digestion except bloated, lowering the adverse-rising QI to resolve phlegm; Radix Glycyrrhizae: sweet, flat, GUIXIN, spleen, lung, stomach warp, invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, heat-clearing and toxic substances removing, alleviation pain relieving, the mitigation property of medicine; Chinese medicine oral liquid of the present invention can be removed the symptom of cough rapidly, and specially medicine is specially controlled, and is evident in efficacy.Points for attention: anemia of pregnant woman's forbidding.

The specific embodiment

Embodiment 1:

Crude drug: 300 parts of Bulbus Fritillariae Cirrhosaes, 300 parts of Fructus Momordicaes, 300 parts of winter folium moris, 150 parts of the Flos Sophorae Immaturus, 150 parts of Semen Raphanis, 20 parts in Radix Glycyrrhizae.

Method for making; Get 300 parts of crude drug Bulbus Fritillariae Cirrhosaes, 300 parts of Fructus Momordicaes, 300 parts of winter folium moris, 150 parts of the Flos Sophorae Immaturus, 150 parts of Semen Raphanis, 20 parts in Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, and decocts secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, and to contain amount of alcohol be 60% to making to add ethanol, stirs evenly, left standstill 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 10%, refined honey 22%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, namely.The adult measures every day three times, each 10ml.

Embodiment 2:

Crude drug: 400 parts of Bulbus Fritillariae Cirrhosaes, 400 parts of Fructus Momordicaes, 400 parts of winter folium moris, 200 parts of the Flos Sophorae Immaturus, 200 parts of Semen Raphanis, 30 parts in Radix Glycyrrhizae.

Method for making; Get 400 parts of crude drug Bulbus Fritillariae Cirrhosaes, 400 parts of Fructus Momordicaes, 400 parts of winter folium moris, 200 parts of the Flos Sophorae Immaturus, 200 parts of Semen Raphanis, 30 parts in Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, and decocts secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, and to contain amount of alcohol be 60% to making to add ethanol, stirs evenly, left standstill 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 10%, refined honey 22%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, namely.The adult measures every day three times, each 10ml.

Embodiment 3:

Crude drug: 200 parts of Bulbus Fritillariae Cirrhosaes, 200 parts of Fructus Momordicaes, 200 parts of winter folium moris, 100 parts of the Flos Sophorae Immaturus, 100 parts of Semen Raphanis, 10 parts in Radix Glycyrrhizae.

Method for making; Get 200 parts of crude drug Bulbus Fritillariae Cirrhosaes, 200 parts of Fructus Momordicaes, 200 parts of winter folium moris, 100 parts of the Flos Sophorae Immaturus, 100 parts of Semen Raphanis, 10 parts in Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, and decocts secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, and to contain amount of alcohol be 60% to making to add ethanol, stirs evenly, left standstill 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 10%, refined honey 22%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, namely.The adult measures every day three times, each 10ml.

Embodiment 4:

Clinical trial

(1) physical data: clinical observation 100 routine patients all have obvious clinical symptoms, and make a definite diagnosis through the clinicist, and wherein the oldest 68 years old, 10 years old, the course of disease is the longest 2 years, and was the shortest 5 days.

(2) Therapeutic Method: oral embodiment 1 Chinese medicine oral liquid, the adult measures every day three times, each 10ml.

(3) treatment standard: cure: cough disappears substantially, and functional rehabilitation is normal.Produce effects: symptom is clearly better, and cough obviously reduces.Take a turn for the better: sx, cough reduces.Invalid: symptom does not have change before and after the medication.

(4) therapeutic outcome: among the 39 routine patients, 27 examples are cured, 8 examples that take a turn for the better, and 4 examples that do not heal, total effective rate is 89.7%.

Embodiment 5:

Model case: tall and erect certain, 32 years old, the woman, cough, sputum is white or yellow, rise morning or night more very, use prescription of the present invention, take the Chinese medicine oral liquid 3 days of this invention, take medicine 1 day 3 times, ampoule 10ml, 3 days take effect, 2 healings courses for the treatment of.

Embodiment 6:

Model case: Chu, 25 years old, the man, cough, expectoration, sputum is white or yellow, takes the Chinese medicine oral liquid 3 days of this invention, take medicine 1 day 3 times, ampoule 10ml, 3 days take effect, and cure 1 course for the treatment of.

Claims

1. a preparation method for the treatment of the cough Chinese medicine oral liquid is characterized in that: comprise the following steps:

Get 400 parts of crude drug Bulbus Fritillariae Cirrhosaes, 400 parts of Fructus Momordicaes, 400 parts of winter folium moris, 200 parts of the Flos Sophorae Immaturus, 200 parts of Semen Raphanis, 30 parts in Radix Glycyrrhizae, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, and decocts secondary, each 1-2 hour, filter, filtrate is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, and to contain amount of alcohol be 60% to making to add ethanol, stirs evenly, left standstill 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum that contains solid weight 65-67%, add sucrose 10%, refined honey 22%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, namely.