CN1333056A - Medicine for treating gastropathy and preparation process thereof - Google Patents
Medicine for treating gastropathy and preparation process thereof Download PDFInfo
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- CN1333056A CN1333056A CN01124615A CN01124615A CN1333056A CN 1333056 A CN1333056 A CN 1333056A CN 01124615 A CN01124615 A CN 01124615A CN 01124615 A CN01124615 A CN 01124615A CN 1333056 A CN1333056 A CN 1333056A
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Abstract
The preparation method of Chinese medicine for curing gastropathy includes the following steps: respectively pulverizing pearl, bovine bezoar and notoginseng into 100-mesh fine powder, soaking clean astragalus decocting pieces in honey and white liquor mixed liquor, stir-frying to yellow, drying in the air and pulverizing to 100-mesh fine powder, mixing the above-mentioned all the powders, curing and sterilizing so as to obtain the invented medicine with obvious therapeutic effect for curing various chronic gastritises and gastro-duodenal ulcer.
Description
The present invention relates to a kind of medicine for the treatment of various chronic gastritiss, gastric and duodenal ulcers, specifically is the Chinese patent medicine of feedstock production with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Various chronic gastritiss, gastric and duodenal ulcers are current global frequently-occurring diseases, according to the interrelated data statistics, have 10% people to suffer from ulcer in life, have 80% people to suffer from gastritis in life.Part treat untimely also can concurrent fatal massive hemorrhage, perforation, canceration etc., human health and quality of life in serious harm.This disease is before the seventies, and treatment is mainly with antacid, spasmolytic, pain relieving, and the protection gastric mucosa is main, and cases with severe then need be considered surgical resection therapy.After the seventies, having occurred in the world with the cimetidine is the H of representative
2Receptor antagonist, fibergastroscope also are applied to clinical.The eighties, the discovery of helicobacter pylori and pathogenesis research in the world, emerging of proton pump inhibitor makes medical circle to the cause of disease, the pathology of various chronic gastritiss, gastric and duodenal ulcers new understanding arranged, and curative effect has also had relative raising.But, because this disease has easy recurrence, point out as " modern gastroenterologys " such as Chen Minzhangs (version in 1998): " modern times in the world new drug constantly emerge, curative effect also improves greatly.But no matter after the sort of Drug therapy, relapse rate then is all more than 70%.For anti-recurrence, the case that has then needs to take medicine for a long time or throughout one's life to keep, no matter the economic like this spending or the toxic and side effects of medicine all can not be ignored.So gastropathy on anti-recurrence, is still a thorny problem.
The object of the present invention is to provide a kind of good effect, medication few, have no side effect, be difficult for the various chronic gastritiss of treatment of recurrence, the Chinese patent medicine of gastric and duodenal ulcers.
Another object of the present invention provides the preparation method of this treatment gastropathy medicine.
Solution of the present invention is on the basis of modern times to the cause of disease of various chronic gastritiss, gastric and duodenal ulcers, pathology understanding, according to inventor's clinical practice for many years, selects its elite composition in the Chinese medicine from the medical treasure-house of motherland is hundreds of.
The formulation weight of medicine of the present invention (part) ratio range is as follows:
Margarita 5-25 Calculus Bovis 3-10 Radix Astragali 30-60 Radix Notoginseng 20-50
Formula optimization weight (part) ratio range of medicine of the present invention is:
Margarita 10-20 Calculus Bovis 5-10 Radix Astragali 35-50 Radix Notoginseng 30-40
Prescription optimum weight (part) proportioning of medicine of the present invention is:
Margarita 15 Calculus Boviss 5.6 Radixs Astragali 42 Radix Notoginseng 37.4
Preparing the used Calculus Bovis of medicine of the present invention can be the artificial Calculus Bovis.
Prepare the used Radix Astragali of medicine of the present invention and preferably adopt the wild Radix Astragali in Inner Mongol.
The pharmacological function that each component of medicine of the present invention is treated various chronic gastritiss, gastric and duodenal ulcers is respectively: during Margarita has and gastric acid, form the effect of layer protecting film and putrefaction removing and tissue regeneration promoting on gastric mucosa.Calculus Bovis has stronger antiinflammatory and kills the effect of helicobacter pylori.The Radix Astragali contains several aminoacid such as saccharide, phlegmatic temperament, choline, has the booster immunization function, its polysaccharide can make spleen inner cell hypertrophy, enhancing antibody synthesize, and have and increase reticuloendothelial system phagocytic function and antibacterial action, the main secretory volume that reduces gastric juice and gastric acid in addition experimental results show that the effect of prevention rat pyloric ligation ulcer.Radix Notoginseng contains arasaponin first and arasaponin second, can shorten clotting time and suppress platelet function, promotes the fibrinolytic effect, also has antiinflammatory to reach the stronger helicobacter pylori activity of killing.
The method that preparation the present invention treats the medicine of gastropathy is:
1, with Margarita, Calculus Bovis, Radix Notoginseng respectively purge drying be crushed to 100 order fine powders;
2, will purify Radix Astragali decoction pieces, the Mel that is equivalent to astragalus weight 25% and 5% white spirit mixed and evenly soak into after, slow fire is processed stir-fry, treats that the jaundice of stilbene sheet, honey are done to take out when tack-free to dry, and is crushed to 100 order fine powders;
3, the powder of above-mentioned each component is sterilized the powder medicine of the gastropathy that can obtain medical treatment by described mixed, ripening.
The medicine that the present invention treats gastropathy can adopt multiple dosage form, can make packed or bottled powder, also can make capsule, can also make honeyed pill, tablet etc.
The clinical drug application result that the present invention treats gastropathy shows that following advantage is arranged: 1, medicine medicine of the present invention source is abundant, and cost is low.2, do not contain any toxic component, take for a long time human body is had no side effect.3, this medicine need not decoct, and can adopt powder, capsule, honeyed pill, tablets and other formulations, and taking convenience meets the national health law regulation.4, the present invention fills a prescription rationally, and drug effect is remarkable, cures the back and is difficult for recurrence.
Since nineteen eighty, example surplus the inventor's the gastropathy special outpatient clinic treatment patients with gastric disease nearly 3000,211 examples are followed up a case by regular visits to and write down to inventor's random observation, and observed result is as follows: man's 86 examples wherein, woman's 125 examples; 14 years old of age minimum, maximum 81 years old, 49 years old mean age; Medical history is the shortest 4 months, and is the longest 36 years, average 7 years; Gastric ulcer 5 examples wherein, duodenal ulcer 18 examples, superficial gastritis 99 examples, duodenal ulcer 37 examples, hypertrophic gastritis 15 examples, reflux gastritis 32 examples, atrophic gastritis 5 examples.The standard that diagnosis and curative effect determinate standard are formulated with reference to Society of Internal Medicine of the national medical association of China gastric abscess (chronic gastritis, gastric and duodenal ulcers),
Recovery from illness: treat further consultation after 3 months, fundamental symptoms all disappears, and feed is normal, and the physico-chemical examination index is normal, adds up to 113 examples, accounts for 53.5%;
Produce effects: treat further consultation after 3 months, symptom obviously alleviates, and it is normal substantially to take food, and physico-chemical examination is taken a favourable turn, and adds up to 69 examples, accounts for 32%;
Take a turn for the better: treat further consultation after 3 months, various sxs, appetite makes moderate progress, and physico-chemical examination changes little, adds up to 28 examples, accounts for 13%;
Invalid: treat further consultation after 3 months, various symptoms and the equal no change of physico-chemical examination add up to 3 examples before and after the treatment, account for 1.5%;
Total effective rate 98.5% is not seen toxic and side effects and untoward reaction.
Model case 1: Zhang Lin, the man 36 years old, lives remote countryside man ditch village, Hongshan District outskirts of a town, Chifeng City, the peasant.Go to a doctor the main suit on February 17th, 2000: the full dull pain of flatulence 5 years, increased the weight of 6 months, flatulence dull pain appears over 5 years often, mouthful vomiting watery fluid, the time have heartburn, every because of catch a cold, angry back sx, taking a small amount of stomach medicine can alleviate, all closely over the past half year diseases are increased the weight of, and particularly flatulence is full, and both sides of the chest are scurried pain.Mongolian medicine hospital's gastroscopy in Chifeng City, examine and be atrophic gastritis, moderate body of stomach and antral gastritis, patient takes medicine of the present invention, every day 3 times, each 2 grams advise eating attention living, cold, sour, peppery, hard, 3 months courses of treatment, after patient took medicine 1 month, the appetite amelioration, distension slightly subtracts, and pain is alleviated slightly, after continuing to take medicine 2 months, patient's flatulence, mouthful stream clear water and dull pain all disappear, and in 22 Nikkei Chifeng City, second hospital gastroscope check May in 2000, examine and are chronic superficial gastritis, the proof atrophic gastritis is fully recovered, and calendar year 2001 follows up a case by regular visits to for twice does not have recurrence.
Model case 2: Yan Guiqin, woman, 47 years old, live ground, Chaoyang, county, enveloping field, Hebei province township, on May 14th, 1989 went to a doctor, and the main suit: the gastric area is property pain after the meal, companion's distension 3 years increased the weight of 3 months, through the Chengde hospital diagnosis and take first cyanogen amidine and hang guanidine, XIANGSHA YANGWEI WAN, treatments such as bismuth aluminate compound, effect is not good enough, and the patient body extremely feeble is kept by transfusion, check that through Chifeng City's hospital gastroscope examine and be antral ulcer, patient takes medicine of the present invention, every day 3 times, each 2 grams, after taking medicine one month, all diseases alleviate, appetite is improved, continued to take medicine 2 months, all disease knowing of having a stomachache are removed, drug withdrawal immediately, follow up a case by regular visits to in May, 1999 nothing recurrence in nearly 10 years.
Embodiment
With preparation double centner medicated powder is example, with 37 kilograms of 12 kilograms of Margaritas, 6 kilograms of Calculus Boviss, Radix Notoginseng respectively purge drying be crushed to 100 order fine powders; After will purifying 11.25 kilograms of 45 kilograms of Radix Astragali decoction pieces, Mel and 2.25 kilograms of mix homogeneously of 50 degree Chinese liquor and soaking into, slow fire is processed and is fried jaundice, takes out when honey is done and dry, and is crushed to 100 order fine powders; Powder mixing, ripening sterilization with above-mentioned each component incapsulate and promptly make capsule Chinese medicine.Each clothes 2 grams of adult, day clothes 3 times, 1-3 the course of treatment.
Claims (6)
1, a kind of medicine for the treatment of gastropathy is characterized in that the medicament Margarita 5-25 Calculus Bovis 3-10 Radix Astragali 30-60 Radix Notoginseng 20-50 that it is made by the following weight proportion raw material
2, the medicine of treatment gastropathy according to claim 1, wherein the weight proportion of various raw materials is Margarita 10-20 Calculus Bovis 5-10 Radix Astragali 35-50 Radix Notoginseng 30-40
3, the medicine of treatment gastropathy according to claim 1, wherein the weight proportion of various raw materials is Margarita 15 Calculus Boviss 5.6 Radixs Astragali 42 Radix Notoginseng 37.4
4,, it is characterized in that described Calculus Bovis is the artificial Calculus Bovis according to the medicine of claim 1,2 or 3 described treatment gastropathy.
5,, it is characterized in that the described Radix Astragali is the wild Radix Astragali that produce in the Inner Mongol according to the medicine of claim 1,2 or 3 described treatment gastropathy.
6, according to the preparation method of the medicine of claim 1,2 or 3 described treatment gastropathy, it is characterized in that with Margarita, Calculus Bovis, Radix Notoginseng respectively purge drying be crushed to 100 order fine powders; With after purifying Radix Astragali decoction pieces, the Mel that is equivalent to astragalus weight 25% and 5% white spirit mixed and evenly soaking into, slow fire is processed stir-fry, treats that the jaundice of stilbene sheet, honey are done to take out when tack-free to dry, and is crushed to 100 order fine powders; The powder of above-mentioned each component is sterilized the powder medicine of the gastropathy that can obtain medical treatment by described mixed, ripening.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01124615A CN1122525C (en) | 2001-07-24 | 2001-07-24 | Medicine for treating gastropathy and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01124615A CN1122525C (en) | 2001-07-24 | 2001-07-24 | Medicine for treating gastropathy and preparation process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1333056A true CN1333056A (en) | 2002-01-30 |
| CN1122525C CN1122525C (en) | 2003-10-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN01124615A Expired - Fee Related CN1122525C (en) | 2001-07-24 | 2001-07-24 | Medicine for treating gastropathy and preparation process thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103599367A (en) * | 2013-11-15 | 2014-02-26 | 刘桂沅 | Capsule for gastrointestinal ulcer and preparation technology thereof |
-
2001
- 2001-07-24 CN CN01124615A patent/CN1122525C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103599367A (en) * | 2013-11-15 | 2014-02-26 | 刘桂沅 | Capsule for gastrointestinal ulcer and preparation technology thereof |
| CN103599367B (en) * | 2013-11-15 | 2016-02-17 | 刘桂沅 | Capsule for gastrointestinal ulcer and preparation technology thereof |
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| Publication number | Publication date |
|---|---|
| CN1122525C (en) | 2003-10-01 |
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