CN1582961A - Improved Chinese medicinal paste for arthralgia and its preparation - Google Patents
Improved Chinese medicinal paste for arthralgia and its preparation Download PDFInfo
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Abstract
An improved Chinese medicine in the form of paste for treating rheumatoid arthritis, rheumatic arthritis and bony arthritis is prepared from 13 Chinese-medicinal materials including gypsum, Sichuan aconite root, ginger, myrrh, etc.
Description
[technical field] the present invention relates to a kind of improvement Chinese medicinal paste and preparation method for the treatment of arthromyodynia, belongs to the field of Chinese medicines.
The alleged arthromyodynia of [background technology] traditional Chinese medical science, similar in appearance to the autoimmune disease of modern medicine, the rheumatism category is such as rheumatoid arthritis, rheumatic arthritis, osteoarthritis, rheumatic fever, rheumatic myositis etc., wherein with rheumatoid arthritis, rheumatic arthritis, osteoarthritis for seeing more.The general employing of western medical treatment is analgesic, antiinflammatory, and analgesic, such as ibuprofen, indometacin etc., severe patient adopts immunosuppressant and hormone therapy, but side effect is big, and the state of an illness is easily repeatedly.The conventional medicament treatment is easy to generate drug resistance, is difficult to prove effective.Aspect physiotherapy, panoramic physiotherapy table and physical therapy method, such as electric therapeutic instrument, the spectrogrph ubiquity and is cost an arm and a leg, and complicated operation uses and owes convenient, needs problems such as prolonged application.Though the tradition mud therapy is effective to the treatment arthromyodynia, can not be still not ideal enough at etiological treatment.The tradition mud therapy is to be the physiotherapy of principle with warm mechanical stimulus, is about to the method that all kinds of mud class materials heating are coated in the certain position treatment of human body arthromyodynia, generally manyly use what mud, mud coal, peat, manually mud etc.Wherein mainly contain a large amount of mineral, biology, Organic substance, inorganic matter etc., have warm, machinery, chemistry, the antibiotic physical action that waits is so be applicable to the treatment of arthromyodynia.But will add warm sludge class material and problem such as clean hygiene not in advance because mud therapy exists, moderns come into disuse more, so traditional mud therapy utmost point is waited to improve.The inventor since nineteen eighty-three so far, last 21 years, traditional mud therapy treatment arthromyodynia is improved and is reformed, exothermic mixture and tcm treatment according to syndrome differentiation mechanism have been invented a kind of Chinese medicinal paste for the treatment of arthromyodynia automatically to introduce chemistry.1995.11.10. we go to the capital achievement of the present invention is reported to State Administration of Traditional Chinese Medicine, in national traditional chinese medical science administration, under the concern and support of the higher level State Scientific and Technological Commission, December in 1996 " the 120 routine clinical researches of mud cream moxibustion treatment arthromyodynia " on the 15th has passed through the city-level scientific achievement and has identified (No. the 16th, Hunan Chang Kejian word [1996]), obtained the third-class progress prize in scientific and collective technology of city-level on April 10th, 1997, (certificate number 963K12, the normal section in Hunan prize word [1997] 02).The connoisseur thinks that achievement in research level of the present invention belongs to " advanced international level ", is " siddhi mud " by the leader of State Administration of Traditional Chinese Medicine praise.Chinese medicinal paste of the present invention is made up of hakuzen soil (stir-fry carbon) 20g Gypsum Fibrosum (forging) 180g, has dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, the function of channels sootheing and network vessel quickening, have warm, mechanical, antibiotic, toxin expelling, detumescence, analgesic effect, be fit to the treatment of arthromyodynia, treatment arthromyodynia effective percentage is reached more than 93%.So far, the clinical research of Chinese medicinal paste treatment arthromyodynia has obtained interim achievement.See " arthromyodynia 120 routine clinical observations are rather treated in hot compress " (59 pages in 1996 the 2nd phase supplementary issues of " Hunan Journal of Traditional Chinese Medicine " 12 volume first about mud cream moxibustion correlational study document, author: She Qinghua, Yang Heming, author unit: commune hospital, Taoyuan county Shuan Xikou township, Taoyuan county Shuan Xikou township poplar is closed bright Chinese herbalist clinic.) back " corner is lifted in mud cream moxibustion clinical practice " (" Chinese medicine Leader, Hunan " 1996.6. the 2nd volume of successively having delivered, 126 pages in the 3rd volume supplementary issue) " acute gastric abscess 32 examples of mud cream therapy for treating " (" Hunan Journal of Traditional Chinese Medicine " 96.9.12 volume, 18 pages in 5 phase supplementary issues) " mud cream moxibustion treatment gastric abscess 108 examples " (" Chinese digests magazine " October the 6th in 1998, volume was 379 pages) " moxibustion of folks of china mud cream " (" practical synthetic medicine " 32 pages, 1998.6 front pages).Above article author and author unit, rank order is all identical.
[summary of the invention] therefore, still there is demand in the Chinese medicinal paste that people better treat arthromyodynia to curative effect, in order to improve the research of Chinese medicinal paste to arthromyodynia, the inventor is on the basis of former Chinese medicinal paste, according to clinical needs, add medicine, Chinese medicinal paste treatment arthromyodynia is improved, and, found a kind of improvement Chinese medicinal paste for the treatment of arthromyodynia that better curative effect is arranged finally by clinical checking repeatedly.
The object of the invention provides a kind of to the more efficiently improvement Chinese medicinal paste of treatment arthromyodynia compositions.Another object of the present invention provides this improvement Chinese medicinal paste preparation of compositions method.
Medicament selection hakuzen soil of the present invention (stir-fry), Gypsum Fibrosum (ripe) makes up, be because Gypsum Fibrosum preparata is a half-H 2 O calcium sulphate, add water and can solidify heat release that temperature can reach about 43 ℃-50 ℃, its clinical effect is: (1), tissue temperature is raise, the blood of heating, blood circulation promoting increases the joint peripheral blood flow, increase joint nutrition, thereby quicken the recovery of function of joint; (2), the skin of heating, make dermalaxia, opening of the pores, the Transdermal absorption of beneficial drug; (3), the medicine of heating, promote medicine dissolution, improve the haemoconcentration of topical remedy, by the skin surface administration, make medicine enter human circulation and produce whole body or local therapeutic effects, thereby set up the diathermanous drug-supplying system of the percutaneous that meets on the modern medicine meaning.Be improvement and innovation, invented the new purposes of effects of Gypsum mud therapy.Hakuzen soil is a parian ware base soil, as making peat through carbonization, wherein contains a large amount of mineral, and human body is had good therapeutical effect.Compendium of Materia Medica is said: " function wins wet spleen invigorating for hakuzen soil, the hot temperature of abnormal smells from the patient." soil can win and wet, also can spleen invigorating, two medicines make up, and have dispelling cold by warming the meridian, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the function of relaxing muscles and tendons and activating QI and blood in the collateral is so be applicable to the treatment of arthromyodynia.Medicament selection Radix Aconiti of the present invention, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae, Rhizoma Zingiberis Recens makes up, and is because the arduous big heat of Radix Aconiti is very toxic, GUIXIN liver, spleen, kidney channel.Effect: dispelling cold by warming the meridian, expelling wind and removing dampness, the meridian dredging, sharp joint.Radix Aconiti Kusnezoffii is hot and big hot, and the toxicity efficacy of a drug is stronger with Radix Aconiti is identical for very toxic function.Rhizoma Arisaematis toil temperature is poisonous, returns liver, spleen, lung meridian.Effect: drying dampness to eliminate phlegm, dispersing swelling and dissipating binds, stopping nausea and vomiting by lowering the adverse flow of QI.Rhizoma Zingiberis Recens is hot.GUIXIN, lung, spleen, stomach warp, effect: relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.This product can also be separated Rhizoma Arisaematis, Rhizoma Pinelliae poison, and the Rhizoma Pinelliae and river, Radix Aconiti Kusnezoffii are combined as eighteen incompatible medicaments, not only do not see its side effect, can promote curative effect mutually on the contrary.This five kinds of Chinese medicine combination has dispelling cold by warming the meridian, and the function of expelling wind and removing dampness collateral dredging is applicable to the treatment of arthromyodynia.This five kinds of Chinese medicine of clinical observation and hakuzen soil, Gypsum Fibrosum preparata combination external application affected part through the cave district, has the effect of slight sweating with relevant.
In order to reach better therapeutic, medicine of the present invention has also added Semen Strychni, Herba Ephedrae, Olibanum, Myrrha makes up, selecting Semen Strychni is because the Semen Strychni bitter cold is very toxic, returns the liver spleen channel, the function removing obstruction in the collateral to relieve pain, contained strychnine has excited strong effect to the central nervous system, select the hot little bitter temperature of Herba Ephedrae for use, return lung, urinary bladder channel.Effect: relieving the exterior syndrome by diaphoresis, antiasthmatic-antitussive, inducing diuresis to remove edema, the modern pharmacological research ephedrine has the effect of stimulating central nervous system function, with the Semen Strychni combination, has the effect of regulating function of nervous system.Selecting Olibanum, is because of Olibanum toil temperature, GUIXIN, and liver, spleen channel, effect: promoting blood circulation and stopping pain, detumescence and promoting granulation is selected Myrrha, is because of Myrrha hardship, flat, GUIXIN, liver, spleen channel.Effect: the blood and relieving pain that looses, detumescence and promoting granulation.Myrrha has local irritant effect, when can be used for angiasthenia with excited vasomotion.This two flavors medicine combination has the function of promoting blood circulation, removing blood stasis and relieving pain, has the effect of regulating vascular function.This four Chinese medicine combination, the activating blood circulation to dissipate blood stasis and dredge the collateral pain relieving has the effect of regulating the nervus vasculairs function.
In order to reach better therapeutic, medicine of the present invention is also selected Pheretima, and Periostracum Serpentis makes up, and selects Pheretima, is because Pheretima is salty-cold, returns liver, lung, and urinary bladder channel, effect: endogenous wind stopping heat clearing away collateral dredging, relieving asthma diuresis.Can be used for arthralgia, hemiplegia.Periostracum Serpentis is sweet salty flat, returns Liver Channel, effect: expelling wind for relieving convulsion, and antipruritic, move back buttocks.This two flavors medicine combination effect: dispelling wind and removing obstruction in the collateral, according to modern pharmacological research, this two flavors medicine combination can replace the clinical use of hormone, has the effect of regulating immunologic function.
Medicine of the present invention can also deduct Herba Ephedrae 3, Olibanum 3, and Myrrha 3, Pheretima 3, Periostracum Serpentis 3 adds the Radix Astragali 15, and Rhizoma Atractylodis 10 are with activating qi and collateral.
Medicine of the present invention can also deduct the Radix Astragali 15 on the basis of said medicine, grey lattice 10 add stone Chang 3, and north thin 3 is with promoting of the circulation of QI and removing the obstruction in the collaterals.
The preparation method of medicine activity component of the present invention is as follows: A, hakuzen soil are fried, calcining gypsum, 126 ℃-180 ℃ of calcine temperature, merge hakuzen soil, Gypsum Fibrosum preparata is ground into fine powder altogether, crosses 100 mesh sieves, make medicine mud cream powder of the present invention, the hermetic container of packing into is standby, prevents to make moist, in order to avoid influence adds the solid heat release of water-setting.B, take by weighing Radix Aconiti by described weight proportion, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Herba Ephedrae, Olibanum, Myrrha, Semen Strychni, Pheretima, Periostracum Serpentis is ground into fine powder, cross 100 mesh sieves, leave and take 1/10th, surplus medicine decocts with water 2 times, and each amount of water was not to have powder 5cm degree of being, boiled 30 minutes, merge decocting liquid twice, it is concentrated to filter to get filtrate, and uses 1/10th medicated powder of being left and taken to extract concentrated solution, dry down at 45 ℃-50 ℃, be ground into fine powder, cross 100 mesh sieves, make medicine activity component of the present invention (claim 5 is the same with claim 6 described medicine activity component method for makings); C, the boiled water furnishing mud paste of when using the mud cream powder of described weight proportion being heated, sharing is on preprepared plastic sheeting, then that medicine activity component of the present invention is very thin and be spread in equably on the mud cream surface, external application affected part or relevant through the cave district, heating soon, temperature is added a cover cotton pad insulation about 43 ℃-50 ℃.
The beneficial effect of medicine of the present invention:
1, the present invention selects hakuzen soil, and Gypsum Fibrosum preparata makes up, and wherein Gypsum Fibrosum preparata is a half-H 2 O calcium sulphate, adds the solid heat release of water-setting, has invented the new purposes of effects of Gypsum, is improvement and the innovation to mud therapy.And the reasonable temperature of having found the calcine half-H 2 O calcium sulphate is 120 ℃-180 ℃, is lower than 126 ℃ then for hydrous calcium sulfate can not solidify heat release, and surpassing 180 ℃ is dead plaster then, adds water and also can not solidify heat release.
2, Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Rehmanniae star, Rhizoma Pinelliae, Rhizoma Zingiberis Recens five kinds of Chinese medicine combination, the product of all big hot Da Xin are with hakuzen soil combination external application affected part or relevantly locate through the cave, discovery has the relieving the exterior syndrome by diaphoresis effect of slight sweating, and " control wind and control blood earlier, the blood sector-style is from going out thereby played traditional Chinese medical science what is called." and " cold effect of from antiperspirant, flowing." Rhizoma Pinelliae and the reverse thinking combination that Radix Aconiti, Radix Aconiti Kusnezoffii make up genus violation eighteen imcompatible pairs combination principle, be used to treat the reaction of arthromyodynia no side effects outward, can promote to treat the curative effect of arthromyodynia on the contrary each other,
3, Herba Ephedrae, Semen Strychni, Olibanum, the combination of Myrrha four medicines has the effect of regulating the nervus vasculairs function.Myrrha has local irritant effect, has invented Myrrha when vasomotion is unable, and the angiokinetic effect of promotion is arranged.
4, same combination report was not seen in Pheretima and Periostracum Serpentis combination in the past, and this combination has similar hormone-like effect according to modern pharmacological research, can replace hormone to use, and has the effect of regulating immunologic function.
The combination of improvement Chinese medicinal paste did not appear in the newspapers yet unexposed delivering in the past clinically.
[specific embodiment] further sets forth beneficial effect of the present invention below by improvement Chinese medicinal paste treatment arthromyodynia 120 routine clinical observation test examples.
1, physical data
This is organized 120 routine arthromyodynia patients and all belongs to clinic case, wherein male 57 examples, women 63 examples, age reckling 12 years old, the maximum 65 years old.The shortest person of the course of disease 3 days, elder 15 years.Chinese medical discrimination typing: migratory arthralgia person's 20 examples, arthralgia aggravated by cold person's 49 examples, damp arthralgia person 45 examples, pyretic arthralgia person 6 examples.Through Western medicine diagnose rheumatoid arthritis 35 examples, rheumatic arthritis 35 examples, osteoarthritis 50 examples.
2, Western medicine diagnose standard:
2.1 rheumatic arthritis diagnostic criteria: before (1), the disease hemolytic streptococcal infection history is arranged more; (2), symptom: four big joints (wrist, elbow, shoulder, ankle, knee joint, hip) migration is scurried pain or is swollen and ache.(3), the sign joint of getting involved is red, swollen, burning pain or swelling, movable function is limited, part patient can have low grade fever concurrently, erythema nodosum or erythema iris, heart change etc.(4), lab testing, ESR increases piece more, ASO (+) (more than the 1:600U) (5), the rarely seen soft tissue swelling of X line, no sclerotin change.(6), deformity is not stayed in prognosis.
2.2 rheumatoid arthritis diagnostic criteria: (1), symptom: based on little joint, mostly be multiple and swell and ache or little joint symmetry swells and ache (more than 6 weeks), morning deadlock.(2), sign: the arthroncus of getting involved, tenderness, movable function is limited, and is lopsided or tetanic, some cases can have subcutaneous nodule.(3), lab testing, RF (+), ESR speeds more.(4), X ray examination: the emphasis joint of getting involved has typical rheumatoid arthritis X line finding.(5), by stages: 1., in early days: swell and ache in the joint and limitation of activity though get involved mostly extremely, and the X line only shows soft tissue swelling and osteoporosis.2., mid-term: the function of joint activity of partly getting involved is obviously limited; X-ray film shows that the joint space narrows down and corrosion in various degree.3., late period: various deformities appear in the majority joint of getting involved, and fiber is tetanic, movable difficulty.X-ray film shows the joint heavy damage, dislocation or fusion.
2.3 bone rheumatic arthritis diagnostic criteria: (1), this organizes 50 examples, takes the photograph sheet through the X line and confirms that a place or many places are lip sample hypertrophy and change 35 examples, the bony spur shape changes 15 examples.(2), all have and ache, twinge, heavy, numbness, a series of clinical symptoms such as unable, very activation is moving limited, can't take care of oneself.
3, tcm diagnosis standard:
3.1 migratory arthralgia, the arthralgia aggravated by cold migration is indefinite, involves the joint, many places, and the companion feels sick, heating, white and thin fur, floating pulse;
3.2 the arthralgia aggravated by cold localized pain, the pain gesture is acute, and meeting trembles with fear then weighs, the joint joint stuffiness, and tongue fur is white, stringy and tense pulse;
Weighing 3.3 damp arthralgia is ached, numbness of the skin is meciless, and limbs are heavy, accompanies nose heave pain as wrapping up in white and greasy fur, soft pulse.
3.4 pyretic arthralgia arthralgia redness, inconvenient activity, the heat that occurs together is thirsty, dry and yellowish fur, slippery and rapid pulse.
4, Therapeutic Method:
All adopt the treatment of improvement Chinese medicinal paste, medicine is formed: hakuzen soil (stir-fry) 20g Gypsum Fibrosum (forging) 180g Radix Aconiti 3g Radix Aconiti Kusnezoffii 3g Rhizoma Arisaematis 3g Rhizoma Pinelliae 3g Rhizoma Zingiberis Recens 3g Herba Ephedrae 3g Olibanum 3g Myrrha 3g Pheretima 3g Periostracum Serpentis 3g Semen Strychni 3g totally 13 flavor Chinese medicines forms.Method for making and usage: A, hakuzen soil is fried, Gypsum Fibrosum (forging) 2 flavor medicines grind to the powder altogether, cross 100 mesh sieves, the hermetic container of packing into, and it is standby to prevent to make moist.Get the mud cream powder boiled water furnishing mud paste of heating during use, sharing is on plastic sheeting; B, with Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae, Herba Ephedrae, Semen Strychni, Olibanum, Myrrha, Pheretima, Periostracum Serpentis takes by weighing by described proportioning, is ground into fine powder, leaves and takes 1/10th, it is standby to cross 100 mesh sieves.Surplus medicine decocts with water secondary, merges to filter, and gets filtrate concentrating, extract medicine activity component with the medicated powder of leaving and taking 1/10th, dry under 45 ℃-50 ℃, be ground into fine powder, cross 100 mesh sieves, make medicine activity component of the present invention, during use medicine of the present invention is sprinkling upon on the mud cream face that is mixed up thinly equably, external application affected part or relevant with pathological changes in the district of cave then, heating soon, temperature is about 43 ℃-50 ℃, add a cover cotton pad insulation, each 30-50 minute, every day 1-2 time, 30 days 1 courses of treatment.
5, therapeutic outcome:
5.1 rheumatic arthritis curative effect judging standard: cure: the arthralgia of getting involved disappears, and joint function recovery is normal, check ESR, ASO, three indexs of leukocyte recover normal, erythema nodosum, and erythema iris disappears, produce effects: the joint of getting involved is clearly better or disappears, ESR, ASO, leukocyte do not recover normal, or recovered normal, but arthralgia does not disappear as yet.Effectively: through treatment the get involved arthralgia or the improvement of swelling and ache.Invalid: through treating more than the course of treatment, the joint symptom of getting involved does not have improvement.
5.2 rheumatoid arthrosis curative effect judging standard: control in the recent period, the arthralgia of getting involved after treatment disappears, and function of joint is improved.Or recovering normal, RF, ESR recover normal, follow up a case by regular visits to not recurrence more than 3 months, produce effects: the arthralgia of getting involved is clearly better or disappears, ESR, the RF titre reduces or has recovered normal, but arthralgia disappearance as yet, effectively: after treatment, the get involved arthralgia or the improvement of swelling and ache; Invalid: through treating 1-3 more than the course of treatment, the arthralgia of getting involved does not have improvement.
5.3 osteoarthritis curative effect judging standard: cure: clinical symptom disappearance such as pain, numbness, functional rehabilitation is normal, and the X line is taken the photograph the sheet check, and hyperosteogeny obviously absorbs and is normal, follows up a case by regular visits to 3 years not recidivists; Effectively: clinical symptoms such as pain, numbness disappear substantially or improve, and function is recovered normal substantially or improved, and the X line is taken the photograph the sheet check, and hyperosteogeny absorbs and dwindles to some extent; Invalid: treatment back symptom, the X line is taken the photograph sheet does not have change.
5.4 therapeutic outcome is added up curative effect through 1-3 the course of treatment.Rheumatic arthritis is totally 35 examples: cure 18 examples, account for 51.43%, produce effects 7 examples account for 20%, and effective 8 examples account for 21.4%, and invalid 2 examples account for 5.7%, and total effective rate is 92.86%; Rheumatoid arthritis is totally 35 examples: control 15 examples in the recent period, account for 42.86%, produce effects 5 examples account for 14.28%, and effective 7 examples account for 20%, and invalid 8 examples account for 21.43%, total effective rate 77.14%; Hyperosteogeny 50 examples: cure 35 examples and account for 70%, produce effects 10 examples account for 20%, and effective 2 examples account for 4%, and invalid 3 examples account for 6%, total effective rate 94%.
6, model case 1: the village so-and-so, woman 30 years old, whole body joint migration pain 1 year, based on double knee joint pain, the heating of local mild swelling, the Changes in weather aggravation, body of the tongue is light red, white and thin fur, pulse condition are carefully slow.Lab testing: erythrocyte sedimentation rate 45mm/h, anti-" 0 " 1:800u, X-ray film: soft tissue swelling is seen in the joint of getting involved, no sclerotin change.Clinical diagnosis is a rheumatic arthritis, and card belongs to migratory arthralgia, control when the expelling wind and removing dampness collateral dredging be main, assistant is with blood circulation promoting and blood stasis dispelling.Acupoint selection: inside and outside Xiyan, after treating 1 course of treatment with the improvement Chinese medicinal paste.The clinical symptoms complete obiteration, joint motion is normal, check: erythrocyte sedimentation rate 12mm/h, anti-" 0 " reduces to 1:400u.
Model case 2: Ao so-and-so, woman 47 years old, nineteen ninety-five first visit on March 2.Frequent waist distending pain, heavy discomfort, aggravation when meeting overcast and rainy wet weather and overworking.Waist persistence distending pain occurs in nearly one month and accompanied right lower extremity pain, light red tongue, tongue is white, stringy and tense pulse.The X ray examination: the L3-L4 vertebral body has lip sample hypertrophy, and L5 has the bony spur hypertrophy.Improved the Chinese medicinal paste external application affected part and the right side obviously place of pain that has a pain in the leg, one day 2 times, 30 days 1 courses of treatment.Through 2 course of therapy, the pain complete obiteration, functional rehabilitation is normal, follows up a case by regular visits to not recurrence.
7, sum up: traditional Chinese medical science arthromyodynia contains the rheumatic fever in the doctor trained in Western medicine, rheumatic arthritis, and rheumatic myositis, rheumatoid arthritis and osteoarthritis etc., with rheumatic arthritis, rheumatoid arthritis, osteoarthritis for seeing more.It is generally acknowledged that rheumatic arthritis belongs to rheumatism, rheumatoid arthritis belongs to autoimmune disease, and osteoarthritis is the degenerative bone pathological changes.The traditional Chinese medical science belongs to the arthromyodynia category, " element is asked. the numbness opinion " say: and " wet three gas of wind and cold are assorted extremely, close and are numbness." for these diseases at present clinically in, Western medicine still do not have special effect medicine therapeutic " element is asked. a shape will piece of writing " point out: " and excessive physical labor and leisurely mood, diease occurrence be in muscle, control to scald." " element is asked. the regulating menstruation opinion " point out: and " sick at bone, pure medicine administered by injection is scalded." the present invention's handle " scalds method " and medicine organically combines, and has invented a kind of improvement Chinese medicinal paste for the treatment of arthromyodynia.Medicine of the present invention is by hakuzen soil, Gypsum Fibrosum preparata, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Herba Ephedrae, Semen Strychni, Olibanum, Myrrha, Pheretima, Periostracum Serpentis 13 flavor Chinese medicines are formed, and wherein hakuzen soil is a parian ware base soil, and Compendium of Material Medica is said: " function wins wet spleen invigorating for hakuzen soil, the hot temperature of abnormal smells from the patient." so control arthromyodynia, be with effectively with hakuzen soil.Gypsum Fibrosum divides Gypsum Fibrosum and Gypsum Fibrosum preparata, and Gypsum Fibrosum is a hydrous calcium sulfate, adds water and can not solidify heat release, Gypsum Fibrosum preparata divides half-H 2 O calcium sulphate and dead plaster, half-H 2 O calcium sulphate adds water can solidify heat release, and temperature can reach 43 ℃ more than-50 ℃, and hydrous calcium sulfate adds water with no dead plaster can not solidify heat release.The present invention introduces half-H 2 O calcium sulphate and solidifies heat release mechanism, and traditional mud therapy is improved and reforms, and has invented the new purposes of effects of Gypsum.According to the traditional Chinese medical science " the numbness person that administers the industry, diffusing wind is main, the resisting cold dampness removing still can not give up." control the traditional Chinese medical science principle of arthralgia aggravated by cold " the big heat of non-Da Xin can not be released it and coagulate cold causing harm also "; the improvement Chinese medicinal paste is selected the Radix Aconiti of the big heat of Da Xin, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis; Rhizoma Pinelliae for use; this five kinds of Chinese medicine combination of Rhizoma Zingiberis Recens, has dispelling cold by warming the meridian, the function of expelling wind and removing dampness; select Herba Ephedrae for use; Semen Strychni, Olibanum, Myrrha is to regulate the nervus vasculairs function.Select Pheretima for use, Periostracum Serpentis is that this 13 flavor medicine combination has dispelling cold by warming the meridian because this two flavors medicine combination has the effect of regulating immunologic function, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the function of channels sootheing and network vessel quickening, have warm, machinery, antibiotic, antiinflammatory, detoxifcation, detumescence, analgesic effect.Be applicable to the treatment of blood stasis type arthromyodynia.The Qi-stagnation type arthromyodynia is gone Herba Ephedrae, Olibanum, and Myrrha, Pheretima, Periostracum Serpentis adds stone Chang, and north is carefully with promoting of the circulation of QI and removing the obstruction in the collaterals.Blood-deficiency type is gone Herba Ephedrae, Olibanum, and Myrrha, Pheretima, Periostracum Serpentis adds the Radix Astragali, and Rhizoma Atractylodis are with activating qi and collateral.
From using modified Chinese medicinal paste 120 routine arthromyodynias are observed, the rheumatic arthritis cure rate reaches 51.43%, total effective rate reaches 92.86%, the recent control rate of rheumatoid arthritis reaches 42.86%, total effective rate reaches 77.14%, and the osteoarthritis cure rate reaches 70%, and total effective rate reaches 94%, show that improvement Chinese medicinal paste curative effect is fine, be fit to the treatment of arthromyodynia.
Claims (7)
1, a kind of medicine for the treatment of arthromyodynia is characterized in that it mainly is made up of materials of weight proportions medicine what follows: hakuzen soil 10-20, Gypsum Fibrosum preparata 90-180.Wherein Gypsum Fibrosum preparata is a half-H 2 O calcium sulphate, adds the solid heat release of water-setting, has invented the new purposes of effects of Gypsum, is improvement and the innovation to mud therapy.And the reasonable temperature of having invented the calcine half-H 2 O calcium sulphate is 120 ℃-180 ℃, is lower than 126 ℃ then for hydrous calcium sulfate can not solidify heat release, and surpassing 180 ℃ is dead plaster then, adds water and also can not solidify heat release.
2, according to claim 1 described medicine, wherein crude drug also has Radix Aconiti 3, Radix Aconiti Kusnezoffii 3, Rhizoma Arisaematis 3, Rhizoma Pinelliae 3, Rhizoma Zingiberis Recens 3.
3, according to claim 2 described medicines, wherein crude drug also has Herba Ephedrae 3, Semen Strychni 3, Olibanum 3, Myrrha 3.
4, according to claim 3 described medicines, wherein crude drug also has Pheretima 3, Periostracum Serpentis 3.
5, according to claim 4 described medicines, it is characterized in that also can deducting Herba Ephedrae 3 in the crude drug, Olibanum 3, Myrrha 3, Pheretima 3, Periostracum Serpentis 3 adds the Radix Astragali 15, Rhizoma Atractylodis 10.
6, according to claim 5 described medicines, it is characterized in that deducting the Radix Astragali 15, Rhizoma Atractylodis 10 add stone Chang 3, and north is thin by 3.
7, according to the preparation method of the described medicine of claim 1-6, it comprises the following steps: A, hakuzen soil stir-fry, calcining gypsum, 126 ℃-180 ℃ of calcine temperature merge hakuzen soil, Gypsum Fibrosum preparata is ground into fine powder altogether, cross 100 mesh sieves, make medicine mud cream powder of the present invention, the hermetic container of packing into is standby, prevent to make moist, in order to avoid influence adds the solid heat release of water-setting.B, take by weighing Radix Aconiti by described weight proportion, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Herba Ephedrae, Olibanum, Myrrha, Semen Strychni, Pheretima, Periostracum Serpentis is ground into fine powder, cross 100 mesh sieves, leave and take 1/10th, surplus medicine decocts with water 2 times, and each amount of water was not to have powder 5cm degree of being, boiled 30 minutes, merge decocting liquid twice, it is concentrated to filter to get filtrate, and uses 1/10th medicated powder of being left and taken to extract concentrated solution, dry down at 45 ℃-50 ℃, be ground into fine powder, cross 100 mesh sieves, make medicine activity component of the present invention (claim 5 is the same with claim 6 described medicine activity component method for makings); C, the boiled water furnishing mud paste of when using the mud cream powder of described weight proportion being heated, sharing is on preprepared plastic sheeting, then that the active component of medicine of the present invention is very thin and be spread in equably on the mud cream surface, external application affected part or relevant through the cave district, heating soon, temperature is added a cover cotton pad insulation about 43 ℃-50 ℃.
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| CNB2004100233116A CN100496596C (en) | 2004-06-15 | 2004-06-15 | Improved Chinese medicinal paste for arthralgia and its preparation |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028930A (en) * | 2010-12-01 | 2011-04-27 | 黎永明 | Medicated wine |
| CN102068634A (en) * | 2010-12-27 | 2011-05-25 | 邱天道 | Externally applied ironing moxibustion clay for human body and manufacturing method thereof |
| CN108210682A (en) * | 2018-02-27 | 2018-06-29 | 黄建民 | A kind of promoting blood circulation medicine puree and preparation method for treating Osteoarthritis |
| CN116920071A (en) * | 2023-09-12 | 2023-10-24 | 中国中医科学院中药研究所 | Application of Xiao ban Tang in preparation of preparation for improving abnormal bone metabolism |
-
2004
- 2004-06-15 CN CNB2004100233116A patent/CN100496596C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028930A (en) * | 2010-12-01 | 2011-04-27 | 黎永明 | Medicated wine |
| CN102068634A (en) * | 2010-12-27 | 2011-05-25 | 邱天道 | Externally applied ironing moxibustion clay for human body and manufacturing method thereof |
| CN102068634B (en) * | 2010-12-27 | 2014-08-06 | 邱天道 | Externally applied ironing moxibustion clay for human body and manufacturing method thereof |
| CN108210682A (en) * | 2018-02-27 | 2018-06-29 | 黄建民 | A kind of promoting blood circulation medicine puree and preparation method for treating Osteoarthritis |
| CN116920071A (en) * | 2023-09-12 | 2023-10-24 | 中国中医科学院中药研究所 | Application of Xiao ban Tang in preparation of preparation for improving abnormal bone metabolism |
| CN116920071B (en) * | 2023-09-12 | 2023-12-19 | 中国中医科学院中药研究所 | Application of Xiao ban Tang in preparation of preparation for improving abnormal bone metabolism |
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| CN100496596C (en) | 2009-06-10 |
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