CN1330338C - Medicine for reinforcing primordial qi of late stage cancer patents - Google Patents
Medicine for reinforcing primordial qi of late stage cancer patents Download PDFInfo
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- CN1330338C CN1330338C CNB2004100738144A CN200410073814A CN1330338C CN 1330338 C CN1330338 C CN 1330338C CN B2004100738144 A CNB2004100738144 A CN B2004100738144A CN 200410073814 A CN200410073814 A CN 200410073814A CN 1330338 C CN1330338 C CN 1330338C
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Abstract
The present invention relates to medicine for reinforcing primordial qi for patients with terminal cancer. The medicine is prepared by combining desertliving cistanche, prepared rehmannia root, pilose asiabell root, glossy privet fruit, angelica, largehead atractylodesrhizome, milk vetch, Chinese magnoliavine fruit, white paeony root and tuckahoe. The present invention can be prepared into dosage forms, such as oral liquid, medicinal powder, tablets, capsules, granules, etc. The present invention can extend the survival time of patients with terminal cancer and improve life quality.
Description
Technical field
The present invention relates to treat the pharmaceutical composition of patients with advanced cancer, particularly the pharmaceutical preparation of preparing with Chinese crude drug.
Background technology
Patients with advanced cancer is because cancerous cell to comprehensive the carrying out property destruction and extremely consuming of organ-tissue, makes patient at the human body be in great misery mentally and day by day among the depletion.When the elimination of tumor was hopeless already, improving the patient was a big task of medical science with the quality of tumor existence.In China and foreign countries' medical practice, also using various extra-nutritions, physical strength reinforcing, raising immunity and various physiological function, and improve the medicine of patient with advanced cancer life quality to easing the pain etc., they respectively have the characteristics of oneself, but still are not known as the medicine generally suitable, respond well to most patients with advanced cancer, that cost is not too high again by medical circle.The depleted syndrome of patients with advanced cancer belongs to vigour by the Chinese medical discrimination theory and very loses even the vigour spent condition.The so-called vigour of the traditional Chinese medical science is the summary to people's vitality, can prolong patient's life to reinforcing primordial qi of late stage cancer patents, improves life quality.Tonifying vital QI is the chief of Chinese medicine.I constantly carry out Chinese medicine " training unit " research and laboratory observation in medical practice for many years, obtained the technological achievement that comprises the present invention.
Summary of the invention
The object of the present invention is to provide a kind of medicine with the Chinese medicine composition preparation, its manufacture method is easy, economical, and is easy to use, and the life quality that improves patient with advanced cancer is had sure effect.
Medicine of the present invention is the medicament of being made by following proportion raw material medicine, and they are expressed as by weight,
Herba Cistanches 15～25 Radix Rehmanniae Preparata 15～25 Radix Codonopsis 10～20 Fructus Ligustri Lucidi 15～25
Radix Angelicae Sinensis 9～16 Rhizoma Atractylodis Macrocephalaes 5～15 Radixs Astragali 15～25 Fructus Schisandrae Chinensis 3～9
The Radix Paeoniae Alba 5～15 Poria 15～25.
Above crude drug preferred weight proportioning is,
Herba Cistanches 16～24 Radix Rehmanniae Preparata 16～24 Radix Codonopsis 12～18 Fructus Ligustri Lucidi 16～24
Radix Angelicae Sinensis 10～15 Rhizoma Atractylodis Macrocephalaes 6～12 Radixs Astragali 16～24 Fructus Schisandrae Chinensis 5～8
The Radix Paeoniae Alba 6～14 Poria 16～24.
Above crude drug optimum weight proportioning is,
Herba Cistanches 20 Radix Rehmanniae Preparata 20 Radix Codonopsis 15 Fructus Ligustri Lucidi 20 Radix Angelicae Sinensis 12
The Rhizoma Atractylodis Macrocephalae 10 Radixs Astragali 20 Fructus Schisandrae Chinensis 6 Radix Paeoniae Albas 12 Poria 20.
Use above crude drug, can adopt common process to make said any dosage form on the pharmaceutics, comprise dosage forms such as powder, tablet, capsule, granular pattern electuary, oral liquid.Preferred oral liquid.
Medicine of the present invention is with " the healthy energy internal memory, heresy can not be done " of the traditional Chinese medical science, and " the kidney spleen is prosperous then from prosperous " argument, is the rule prescription with " nourishing kidney spleen invigorating, Baconic's complement ", has the right supporting anticancer effect.Wherein multiple medicine can activate or strengthen T lymphocytes in human body and the bone-marrow-derived lymphocyte kill capability to tumor cell, enriching yin and nourishing kidney, invigorating the spleen and benefiting QI, qi and blood tonifying, prolong middle and terminal cancer patient life cycle from the mechanism of tonifying vital QI, improve the quality of life of patient with tumor existence.Medicine of the present invention also can be used as the auxiliary treatment means of radiotherapy, chemotherapy, operative treatment.
The specific embodiment
The invention will be further described by the following examples.
Embodiment 1 produces oral liquid
Prescription: Herba Cistanches 2000 gram Radix Rehmanniae Preparata 2000 gram Radix Codonopsis 1500 gram Fructus Ligustri Lucidi 2000 grams
The Radix Angelicae Sinensis 1200 gram Rhizoma Atractylodis Macrocephalaes 1000 gram Radixs Astragali 2000 gram Fructus Schisandrae Chinensis 600 grams
The Radix Paeoniae Alba 1200 gram Poria 2000 grams
Preparation method: each medicine is decocted with water respectively 3 times, decocted 30～120 minutes at every turn, merge decoction liquor and filter, be concentrated into relative density 1.1 grams per milliliters, add the ethanol mix homogeneously, make mixed liquor contain alcohol 50%; Left standstill 24 hours, and got supernatant and reclaim ethanol, be condensed into the thick paste that relative density is 1.3 grams per milliliters, oven drying at low temperature is modulated into oral liquid again.
Present embodiment uses crude drug totally 15500 grams, can be made into 7000 milliliters of oral liquids, and per 10 milliliters contain about 22 grams of crude drug equivalent.Each oral 10～20 milliliters of adult patients, every day 3～4 times.
Embodiment 2 produces tablet
Prescription: Herba Cistanches 2200 gram Radix Rehmanniae Preparata 2200 gram Radix Codonopsis 1500 gram Fructus Ligustri Lucidi 2400 grams
The Radix Angelicae Sinensis 1000 gram Rhizoma Atractylodis Macrocephalaes 800 gram Radixs Astragali 2000 gram Fructus Schisandrae Chinensis 600 grams
The Radix Paeoniae Alba 1200 gram Poria 2000 grams
1. with Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Radix Astragali pulverize separately, cross 200 mesh sieves, mix homogeneously is standby.
2. all the other each medicines are merged and soak into back decoction 3 times, decocted 30～120 minutes at every turn, merge decoction liquor and filter, be condensed into clear paste.
3. in clear paste, add the made medicated powder of step 1, make granule, drying, compacting is in blocks, and sugar coating promptly gets the tablet finished product.
Present embodiment uses crude drug totally 15900 grams, can be made into 5000 in tablet, and every contains about 3.1 grams of crude drug equivalent.Each oral 3～4 of adult patients, every day 3～4 times.
Embodiment 3 produces capsule
Prescription: Herba Cistanches 2000 gram Radix Rehmanniae Preparata 2000 gram Radix Codonopsis 1500 gram Fructus Ligustri Lucidi 2200 grams
The Radix Angelicae Sinensis 1200 gram Rhizoma Atractylodis Macrocephalaes 1000 gram Radixs Astragali 2000 gram Fructus Schisandrae Chinensis 500 grams
The Radix Paeoniae Alba 1200 gram Poria 2000 grams
Preparation method:
1. Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Radix Astragali pulverize separately are crossed 150 mesh sieves, and mix homogeneously is standby.
2. each medicine is merged and soak into back decoction 3 times, decocted 30～120 minutes at every turn, merge decoction liquor and filter, be condensed into clear paste.
3. in clear paste, add the made medicated powder of step 1, make granule, spray-dried, make fine powder, the adding vegetable oil is mixed the back pelletize thoroughly and is made capsule in fine powder again.
Present embodiment uses crude drug totally 15600 grams, can be made into about 6000 of capsule, and every contains about 2.7 grams of crude drug equivalent.Each oral 4～6 of adult patients, every day 3～4 times.
Experimental example treatment middle and advanced stage solid carcinoma 268 routine clinical observation on the therapeutic effect
During 5 years 268 routine middle and advanced stage solid carcinoma patients are used medicine of the present invention nearly and implement treatment, carry out clinical observation.All cases all give the oral liquid by the making of the embodiment of the invention 1 method, and each oral 10～20 milliliters, every day 3～4 times.Continuous use 30 days was a course of treatment.After medication 2～4 courses of treatment, there is 213 examples (79.5%) food to receive and increases slightly, weak alleviating, sleep increases, and the anemia looks are improved (erythrocyte and hemoglobin improve).61 examples are used medicine of the present invention during radiotherapy, multiplely alleviate to some extent at the common toxicity of radiation period: xerostomia, weak alleviating, food receive and obviously reduce, and radiocurable toleration is improved.73 examples are used medicine of the present invention before and after chemotherapy, the performance nausea and vomiting reduces or alleviates dizziness, weak alleviating. and clinical case shows that also medicine of the present invention has the effect of certain protection marrow function.73 examples are used medicine person of the present invention before and after chemotherapy, none example of blood leukocytes number drops to 1.0 * 10
9/ L does not just have 4 routine blood leukocytes numbers to drop to 1.0 * 10 and use in matched group 48 examples of medicine of the present invention
9/ L.All are used medicine person of the present invention and there is no untoward reaction.
Claims (4)
1. a medicine that is used for reinforcing primordial qi of late stage cancer patents is characterized in that, pharmacodynamic raw materials and the weight proportion thereof of making it are:
Herba Cistanches 15～25 Radix Rehmanniae Preparata 15～25 Radix Codonopsis 10～20 Fructus Ligustri Lucidi 15～25
Radix Angelicae Sinensis 9～16 Rhizoma Atractylodis Macrocephalaes 5～15 Radixs Astragali 15～25 Fructus Schisandrae Chinensis 3～9
The Radix Paeoniae Alba 5～15 Poria 15～25.
2. medicine according to claim 1 is characterized in that, raw materials used weight proportion is:
Herba Cistanches 16～24 Radix Rehmanniae Preparata 16～24 Radix Codonopsis 12～18 Fructus Ligustri Lucidi 16～24
Radix Angelicae Sinensis 10～15 Rhizoma Atractylodis Macrocephalaes 6～12 Radixs Astragali 16～24 flavor 5～8
The Radix Paeoniae Alba 6～14 Poria 16～24.
3. medicine according to claim 1 is characterized in that, raw materials used weight proportion is:
Herba Cistanches 20 Radix Rehmanniae Preparata 20 Radix Codonopsis 15 Fructus Ligustri Lucidi 20 Radix Angelicae Sinensis 12
Sub 6 Radix Paeoniae Albas, 12 Poria 20 of the Rhizoma Atractylodis Macrocephalae 10 Radixs Astragali, 20 flavors.
4. medicine according to claim 1 is characterized in that its dosage form is an oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100738144A CN1330338C (en) | 2004-09-03 | 2004-09-03 | Medicine for reinforcing primordial qi of late stage cancer patents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100738144A CN1330338C (en) | 2004-09-03 | 2004-09-03 | Medicine for reinforcing primordial qi of late stage cancer patents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1628823A CN1628823A (en) | 2005-06-22 |
| CN1330338C true CN1330338C (en) | 2007-08-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2004100738144A Expired - Fee Related CN1330338C (en) | 2004-09-03 | 2004-09-03 | Medicine for reinforcing primordial qi of late stage cancer patents |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100998769B (en) * | 2006-12-25 | 2011-04-06 | 隋丽红 | Chinese medicine decoction for anti-cancer and strengthening the body resistance |
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2004
- 2004-09-03 CN CNB2004100738144A patent/CN1330338C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 扶正活血抗癌方合并化疗治疗胃癌(术后)的临床与实验研究 周阿高，中国中西医结合杂志，第16卷第9期 1996 * |
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| CN1628823A (en) | 2005-06-22 |
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