CN1327860C - Prepared Chinese medicine for treating yang disease of boil caused by accumulated noxious heat - Google Patents

Prepared Chinese medicine for treating yang disease of boil caused by accumulated noxious heat Download PDF

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Publication number
CN1327860C
CN1327860C CNB03117227XA CN03117227A CN1327860C CN 1327860 C CN1327860 C CN 1327860C CN B03117227X A CNB03117227X A CN B03117227XA CN 03117227 A CN03117227 A CN 03117227A CN 1327860 C CN1327860 C CN 1327860C
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China
Prior art keywords
liquid
borneolum syntheticum
filtering
chinese patent
patent medicine
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Expired - Lifetime
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CNB03117227XA
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Chinese (zh)
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CN1519007A (en
Inventor
孔农
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Guizhou Runsheng Pharmacy Co ltd
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BENCAOTANG MEDICINE Co Ltd GUIZHOU
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Abstract

The present invention relates to a Chinese patent medicine for sore yang diseases of caused by noxious heat accumulation. 75 to 175 of Tinospora root and 1 to 10 of borneol are pulverized, extracted by ethanol, concentrated into extract and uniformly mixed. The mixture is made into a liquid preparation or a solid preparation by a conventional technology. In the present invention, principal and auxiliary medicines are matched. The patent medicine has the efficiency for clearing away heat and toxic materials, eliminating swellings and alleviating pain, and can effectively cure sore yang diseases caused by noxious heat accumulation.

Description

A kind of treat pyretic toxicity pent up due to the Chinese patent medicine of swelling and ulcer
Technical field: the invention belongs to the Chinese patent medicine pharmaceutical technology, specifically be a kind of treat pyretic toxicity pent up due to the Chinese patent medicine of skin infection sun disease.
Technical background: skin infection sun disease was common clinical disease due to pyretic toxicity pented up, show as innominate toxic swelling, carbuncle skin ulcer, lymphadenitis, cellulitis, phlebitis, its characteristics are the local red and swollen heat pain of pathological changes, or with heating, headache, thirsty, General Symptomies such as yellow urine is few, constipation with dry stool.The Seedling doctor is called " fiery Huang " (Jend refers to the shallow property of acute table suppurative illness).And think that etiology and pathogenesis is the fire-toxin blood trouble, due to heat in blood is pented up.
1, Radix Tinosporae, this product are the dried root of menispermaceae plant limacia sagittata Tinospora sagittata (olio.) Gagnep or Radix Tinosporae Tinospora capillipes Gagnep.Property is cold, and bitter in the mouth has the function of heat-clearing and toxic substances removing.
2, Borneolum Syntheticum, this product are the crisp crystallization of water white lamellar.The cold acrid in the mouth of property is gone into hot warp, diffusing stagnated fire is arranged, the reducing swelling and alleviating pain function.
Summary of the invention: the present invention is according to Miao ethnic group's theory of medicine, propose the treatment pyretic toxicity pent up due to the Chinese patent medicine of skin infection sun disease.
Component of the present invention (weight ratio) is: Radix Tinosporae: Borneolum Syntheticum=(75-175): (1-10).Get above two flavor medical materials, Radix Tinosporae was ground into coarse granule, with 10-95% ethanol moistening 10-24 hour, make solvent with 25-95% ethanol, flooded 0-96 hour, slowly percolation, collect the liquid of just filtering, device is preserved in addition, continues percolation, collect the continuous liquid of filtering, the medicinal residues squeezing merges press juice and the continuous liquid of filtering, and is being concentrated into the extractum that relative density is 1.05-1.40 (35-80 a ℃) below 25-100 ℃, add the liquid of just filtering, add Borneolum Syntheticum behind the mixing and produce liquid preparation or solid preparation with conventional pharmaceutical technology.
Main ingredient 5 usefulness of the present invention, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, can effectively treat pyretic toxicity pent up due to skin infection sun disease.
The specific embodiment:
Embodiment one, gets Radix Tinosporae 1000g, Borneolum Syntheticum 10g.More than two the flavor medical materials, Radix Tinosporae is ground into coarse granule, spends the night with 85% ethanol 300ml moistening, make solvent with 85% ethanol, flooded 48 hours, slowly percolation, collect the liquid 850ml that just filters, device is preserved in addition, continues percolation, till the nearly colourless or little yellow of the liquid of filtering, collect the continuous liquid of filtering, the medicinal residues squeezing merges press juice and the continuous liquid of filtering, be concentrated into the extractum that relative density is 1.30 (6 0 ℃) below 60 ℃, add the liquid of just filtering, mix, add Borneolum Syntheticum and polyvinyl formal-acetal, mixing, add 85% ethanol to ormal weight, mixing leaves standstill, filter, promptly.
Embodiment two, get Radix Tinosporae 750g, Borneolum Syntheticum 30g.More than two the flavor medical materials, Radix Tinosporae is ground into coarse granule, spends the night with 85% ethanol 300ml moistening, make solvent with 85% ethanol, flooded 48 hours, slowly percolation, collect the liquid 850ml that just filters, device is preserved in addition, continues percolation, till the nearly colourless or little yellow of the liquid of filtering, collect the continuous liquid of filtering, the medicinal residues squeezing merges press juice and the continuous liquid of filtering, and is being concentrated into the extractum that relative density is 1.30 (60 ℃) below 60 ℃, add the liquid of just filtering, mixing reclaims ethanol, is being concentrated into the extractum that relative density is 1.05-1.40 (35-80 a ℃) below 25-100 ℃, add adjuvant, make granule, oven dry adds the Borneolum Syntheticum powder mixing and makes granule; Granule dress capsule or tabletting with mixing Borneolum Syntheticum powder can make solid preparations such as capsule or tablet.
Embodiment three, get Radix Tinosporae 1500g, Borneolum Syntheticum 35g.More than two the flavor medical materials, Radix Tinosporae is ground into coarse granule, spend the night with 85% ethanol 300ml moistening, make solvent with 85% ethanol, flooded 48 hours, slowly percolation, collection is filtered till the extremely nearly colourless or little yellow of liquid, mixing extracts palmatine hydrochloride with the Amberlyst process purification, with purification palmatine hydrochloride and Borneolum Syntheticum with the appropriate solvent dissolving after routinely technology make injection.Or earlier the purification palmatine hydrochloride is made granule, adding behind the Borneolum Syntheticum powder routinely, the technology preparation becomes solid preparation.

Claims (15)

  1. One kind treat pyretic toxicity pent up due to the Chinese patent medicine of skin infection sun disease, it is characterized in that it is that Radix Tinosporae, the Borneolum Syntheticum of 75-175: 1-10 is that composition and effectiveness and the acceptable accessories that raw material is made formed by weight ratio.
  2. 2. according to the described Chinese patent medicine of claim 1, wherein be to be the composition and effectiveness that raw material is made by the Radix Tinosporae of 1000g, the Borneolum Syntheticum of 10g.
  3. 3. according to the described Chinese patent medicine of claim 1, wherein be to be the composition and effectiveness that raw material is made by the Radix Tinosporae of 750g, the Borneolum Syntheticum of 30g.
  4. 4. according to the described Chinese patent medicine of claim 1, wherein be to be the composition and effectiveness that raw material is made by the Radix Tinosporae of 1500g, the Borneolum Syntheticum of 35g.
  5. 5. according to any one described Chinese patent medicine among claims 1-4, it is characterized in that it is liquid preparation, capsule, tablet or injection.
  6. 6. method of producing the described Chinese patent medicine of claim 1, it is characterized in that with weight ratio being the Radix Tinosporae of 75-175: 1-10, Borneolum Syntheticum, get Radix Tinosporae and be ground into coarse granule,, make solvent with 25-95% ethanol with 10-95% ethanol moistening 10-24 hour, flooded 0-96 hour, slowly percolation is collected the liquid of just filtering, and device is preserved in addition, continue percolation, collect the continuous liquid of filtering, the medicinal residues squeezing merges press juice and the continuous liquid of filtering, being concentrated into 35-80 ℃ of survey relative density below 25-100 ℃ is the extractum of 1.05-1.40, add the liquid of just filtering, mixing adds Borneolum Syntheticum, mixing is made solid preparation or liquid preparation with production technology commonly used.
  7. 7. according to the described Chinese patent medicine production method of claim 6, it is characterized in that Radix Tinosporae with 1000g, the Borneolum Syntheticum of 10g is got Radix Tinosporae and is ground into coarse granule, spends the night with 85% ethanol 300ml moistening, make solvent with 85% ethanol, flooded 48 hours, slowly percolation is collected the liquid 850ml that just filters, device is preserved in addition, continue percolation, till the nearly colourless or little yellow of the liquid of filtering, collect the continuous liquid of filtering, the medicinal residues squeezing, press juice and the continuous liquid of filtering are merged, and to survey relative densities be 1.30 extractum being concentrated into 60 ℃ below 60 ℃, adds the liquid of just filtering, mixing, add Borneolum Syntheticum, mixing is made solid preparation or liquid preparation with production technology commonly used.
  8. 8. according to the described Chinese patent medicine production method of claim 6, it is characterized in that Radix Tinosporae with 750g, the Borneolum Syntheticum of 30g, get Radix Tinosporae and be ground into coarse granule, spend the night with 85% ethanol 300ml moistening, make solvent, flooded 48 hours with 85% ethanol, percolation slowly, collect the liquid 850ml that just filters, device is preserved in addition, continues percolation, till the nearly colourless or little yellow of the liquid of filtering, collect the continuous liquid of filtering, the medicinal residues squeezing merges press juice and the continuous liquid of filtering, to survey relative densities be 1.30 extractum being concentrated into 60 ℃ below 60 ℃, add the liquid of just filtering, mixing reclaims ethanol, being concentrated into 35-80 ℃ of survey relative density below 25-100 ℃ is the extractum of 1.05-1.40, add Borneolum Syntheticum, mixing is made solid preparation or liquid preparation with production technology commonly used.
  9. 9. according to the described Chinese patent medicine production method of claim 6, it is characterized in that the Radix Tinosporae of 1500g, the Borneolum Syntheticum of 35g, get Radix Tinosporae and be ground into coarse granule, spend the night, make solvent with 85% ethanol with 85% ethanol 300ml moistening, flooded 48 hours, slowly percolation is collected till the nearly colourless or little yellow of the liquid of filtering mixing, extract palmatine hydrochloride with the Amberlyst process purification, purification palmatine hydrochloride and Borneolum Syntheticum are made solid preparation or liquid preparation with production technology commonly used.
  10. 10. according to any one described Chinese patent medicine production method among the claim 6-9, wherein extractum is added adjuvants such as polyvinyl formal-acetal, mixing obtains the liquid preparation of different size.
  11. 11. according to any one described Chinese patent medicine production method among the claim 6-9, wherein extractum is added adjuvant and make granule, drying adds the Borneolum Syntheticum powder mixing, obtains granule.
  12. 12. according to the described Chinese patent medicine production method of claim 11, wherein extractum is added adjuvant and make granule, drying adds the Borneolum Syntheticum powder mixing, adorns capsule, obtains the capsule of different size.
  13. 13. according to the described Chinese patent medicine production method of claim 11, wherein extractum is added adjuvant and make granule, drying adds the Borneolum Syntheticum powder mixing, tabletting obtains the tablet of different size.
  14. 14. according to any one described Chinese patent medicine production method among the claim 6-9, the wherein resulting liquid of filtering extracts palmatine hydrochloride with the Amberlyst process purification, and purification palmatine hydrochloride and Borneolum Syntheticum are dissolved with appropriate solvent, is mixed with the injection of different size.
  15. 15. according to any one described Chinese patent medicine production method among the claim 6-9, the wherein resulting liquid of filtering extracts palmatine hydrochloride with the Amberlyst process purification, the purification palmatine hydrochloride is added adjuvant make granule, add the Borneolum Syntheticum powder mixing, make solid preparation with production technology commonly used.
CNB03117227XA 2003-01-21 2003-01-21 Prepared Chinese medicine for treating yang disease of boil caused by accumulated noxious heat Expired - Lifetime CN1327860C (en)

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CN1327860C true CN1327860C (en) 2007-07-25

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329072C (en) * 2005-11-23 2007-08-01 赵剑锋 Medicine for treating infant's fever and cough and preparing method
CN104257866B (en) * 2014-09-16 2016-07-20 韩旭 Pharmaceutical composition and pharmaceutical preparation and application thereof
CN110538304B (en) * 2019-10-24 2021-08-13 崔公让 Chinese medicinal preparation and its preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国家药品监督管理局 国家中成药标准汇编中成药地方标准上升国家标准部分,第外科妇科分册卷 2002 *

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