CN1324367A - 环状前塞波素衍生肽及其应用 - Google Patents

环状前塞波素衍生肽及其应用 Download PDF

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Publication number
CN1324367A
CN1324367A CN99812627A CN99812627A CN1324367A CN 1324367 A CN1324367 A CN 1324367A CN 99812627 A CN99812627 A CN 99812627A CN 99812627 A CN99812627 A CN 99812627A CN 1324367 A CN1324367 A CN 1324367A
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CN
China
Prior art keywords
amino acid
peptide
acid
hydrophobic amino
seq
Prior art date
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Pending
Application number
CN99812627A
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English (en)
Chinese (zh)
Inventor
戴维·E·赖特
约翰·S·奥布赖恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Myelos Corp
Original Assignee
Myelos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myelos Corp filed Critical Myelos Corp
Publication of CN1324367A publication Critical patent/CN1324367A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN99812627A 1998-08-28 1999-08-20 环状前塞波素衍生肽及其应用 Pending CN1324367A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9835998P 1998-08-28 1998-08-28
US60/098,359 1998-08-28

Publications (1)

Publication Number Publication Date
CN1324367A true CN1324367A (zh) 2001-11-28

Family

ID=22268937

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99812627A Pending CN1324367A (zh) 1998-08-28 1999-08-20 环状前塞波素衍生肽及其应用

Country Status (13)

Country Link
EP (1) EP1105420A1 (cg-RX-API-DMAC7.html)
JP (2) JP4528443B2 (cg-RX-API-DMAC7.html)
KR (1) KR20010079695A (cg-RX-API-DMAC7.html)
CN (1) CN1324367A (cg-RX-API-DMAC7.html)
AU (1) AU751034B2 (cg-RX-API-DMAC7.html)
BR (1) BR9913490A (cg-RX-API-DMAC7.html)
CA (1) CA2341810A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ2001655A3 (cg-RX-API-DMAC7.html)
HU (1) HUP0103265A3 (cg-RX-API-DMAC7.html)
IL (1) IL141586A0 (cg-RX-API-DMAC7.html)
PL (1) PL204359B1 (cg-RX-API-DMAC7.html)
WO (1) WO2000012553A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200102489B (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366286C (zh) * 2003-04-28 2008-02-06 常州南云科技有限公司 Saposin C-DOPS:一种抗癌新药
CN103275187A (zh) * 2013-06-14 2013-09-04 四川科伦新光生物科技开发有限公司 一种镇痛肽fi及其基因和应用

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571787A (en) 1993-07-30 1996-11-05 Myelos Corporation Prosaposin as a neurotrophic factor
WO2000012553A1 (en) * 1998-08-28 2000-03-09 Myelos Corporation Cyclic prosaposin-derived peptides and uses thereof
AUPQ084899A0 (en) * 1999-06-08 1999-07-01 University Of Melbourne, The Neurotrophin agonists
IL137820A (en) * 2000-08-10 2009-06-15 S I S Shulov Inst For Science Pharmaceutical composition for topical administration comprising an analgesic peptide
EP2020988B1 (en) 2006-04-28 2017-08-16 Children's Hospital Medical Center Compositions comprising fusogenic proteins or polypeptides derived from prosaposin for application in transmembrane drug delivery systems
CA2666953A1 (en) * 2006-10-20 2008-05-02 Children's Hospital Medical Center Spontaneous forming ellipsoidal phospholipid unilamellar vesicles
JP7066412B2 (ja) 2015-04-23 2022-05-13 ザ プロクター アンド ギャンブル カンパニー 界面活性剤可溶性抗ふけ剤の送達
CN108697609A (zh) 2016-03-03 2018-10-23 宝洁公司 气溶胶去头皮屑组合物
WO2018075846A1 (en) 2016-10-21 2018-04-26 The Procter & Gamble Company Concentrated shampoo dosage of foam designating hair conditioning benefits
US20180110688A1 (en) 2016-10-21 2018-04-26 The Procter & Gamble Company Concentrated Shampoo Dosage of Foam for Providing Hair Care Benefits
WO2018075850A1 (en) 2016-10-21 2018-04-26 The Procter & Gamble Company Dosage of foam for delivering consumer desired dosage volume and surfactant amount in an optimal formulation space
CN109843252A (zh) 2016-10-21 2019-06-04 宝洁公司 指定毛发体积有益效果的浓缩型洗发剂泡沫剂型
WO2018075855A1 (en) 2016-10-21 2018-04-26 The Procter & Gamble Company Dosage of foam for delivering consumer desired dosage volume, surfactant amount, and scalp health agent amount in an optimal formulation space
EP3528780A1 (en) 2016-10-21 2019-08-28 The Procter and Gamble Company Stable compact shampoo products with low viscosity and viscosity reducing agent
EP3528896A1 (en) 2016-10-21 2019-08-28 The Procter & Gamble Company Concentrated shampoo dosage of foam for providing hair care benefits
US11224567B2 (en) 2017-06-06 2022-01-18 The Procter And Gamble Company Hair compositions comprising a cationic polymer/silicone mixture providing improved in-use wet feel
US11679073B2 (en) 2017-06-06 2023-06-20 The Procter & Gamble Company Hair compositions providing improved in-use wet feel
US11141370B2 (en) 2017-06-06 2021-10-12 The Procter And Gamble Company Hair compositions comprising a cationic polymer mixture and providing improved in-use wet feel
US20190105246A1 (en) 2017-10-10 2019-04-11 The Procter & Gamble Company Sulfate free personal cleansing composition comprising low inorganic salt
EP3694479A1 (en) 2017-10-10 2020-08-19 The Procter and Gamble Company A method of treating hair or skin with a personal care composition in a foam form
WO2019074989A1 (en) 2017-10-10 2019-04-18 The Procter & Gamble Company COMPACT SHAMPOO COMPOSITION CONTAINING SULFATE-FREE SURFACTANTS
US11116705B2 (en) 2017-10-10 2021-09-14 The Procter And Gamble Company Compact shampoo composition containing sulfate-free surfactants
CN111556743B (zh) 2017-12-20 2023-07-18 宝洁公司 包含硅氧烷聚合物的澄清洗发剂组合物
CN112367963A (zh) 2018-06-29 2021-02-12 宝洁公司 低表面活性剂气溶胶去头皮屑组合物
US12226505B2 (en) 2018-10-25 2025-02-18 The Procter & Gamble Company Compositions having enhanced deposition of surfactant-soluble anti-dandruff agents
MX2022005533A (es) 2019-12-06 2022-06-08 Procter & Gamble Composicion libre de sulfato con deposito mejorado del activo para el cuero cabelludo.
US11679065B2 (en) 2020-02-27 2023-06-20 The Procter & Gamble Company Compositions with sulfur having enhanced efficacy and aesthetics
JP7678101B2 (ja) 2020-11-23 2025-05-15 ザ プロクター アンド ギャンブル カンパニー 硫酸化界面活性剤を含まないパーソナルケア組成物
US11819474B2 (en) 2020-12-04 2023-11-21 The Procter & Gamble Company Hair care compositions comprising malodor reduction materials
US12409125B2 (en) 2021-05-14 2025-09-09 The Procter & Gamble Company Shampoo compositions containing a sulfate-free surfactant system and sclerotium gum thickener
US11986543B2 (en) 2021-06-01 2024-05-21 The Procter & Gamble Company Rinse-off compositions with a surfactant system that is substantially free of sulfate-based surfactants
US12458575B2 (en) 2021-12-09 2025-11-04 The Procter & Gamble Company Sulfate free personal cleansing composition comprising effective preservation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106106A0 (en) * 1993-06-22 1993-10-20 Interpharm Lab Ltd Library of polymeric molecules and its preparation
US6271196B1 (en) * 1996-03-05 2001-08-07 Regents Of The University Of Ca Methods of alleviating neuropathic pain using prosaposin-derived peptides
WO2000012553A1 (en) * 1998-08-28 2000-03-09 Myelos Corporation Cyclic prosaposin-derived peptides and uses thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366286C (zh) * 2003-04-28 2008-02-06 常州南云科技有限公司 Saposin C-DOPS:一种抗癌新药
CN103275187A (zh) * 2013-06-14 2013-09-04 四川科伦新光生物科技开发有限公司 一种镇痛肽fi及其基因和应用
CN103275187B (zh) * 2013-06-14 2014-10-29 四川合泰新光生物科技有限公司 一种镇痛肽fi及其基因和应用

Also Published As

Publication number Publication date
HUP0103265A2 (hu) 2002-02-28
CZ2001655A3 (cs) 2001-11-14
WO2000012553A1 (en) 2000-03-09
JP2002523518A (ja) 2002-07-30
ZA200102489B (en) 2002-06-04
JP2010150272A (ja) 2010-07-08
JP4528443B2 (ja) 2010-08-18
PL204359B1 (pl) 2010-01-29
KR20010079695A (ko) 2001-08-22
HUP0103265A3 (en) 2002-09-30
BR9913490A (pt) 2001-09-25
IL141586A0 (en) 2002-03-10
PL346346A1 (en) 2002-02-11
AU751034B2 (en) 2002-08-08
CA2341810A1 (en) 2000-03-09
AU5690599A (en) 2000-03-21
EP1105420A1 (en) 2001-06-13

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication