CN1322127C - 来自脑膜炎奈瑟氏球菌的basb029多核苷酸和多肽 - Google Patents

来自脑膜炎奈瑟氏球菌的basb029多核苷酸和多肽 Download PDF

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Publication number
CN1322127C
CN1322127C CNB998086061A CN99808606A CN1322127C CN 1322127 C CN1322127 C CN 1322127C CN B998086061 A CNB998086061 A CN B998086061A CN 99808606 A CN99808606 A CN 99808606A CN 1322127 C CN1322127 C CN 1322127C
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China
Prior art keywords
polypeptide
polynucleotide
seq
sequence
basb029
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Expired - Fee Related
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CNB998086061A
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English (en)
Chinese (zh)
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CN1309707A (zh
Inventor
J·－L·吕勒
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GlaxoSmithKline Biologicals SA
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SmithKline Beecham Biologicals SA
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Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Publication of CN1309707A publication Critical patent/CN1309707A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
CNB998086061A 1998-05-13 1999-05-07 来自脑膜炎奈瑟氏球菌的basb029多核苷酸和多肽 Expired - Fee Related CN1322127C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9810276.7 1998-05-13
GBGB9810276.7A GB9810276D0 (en) 1998-05-13 1998-05-13 Novel compounds

Publications (2)

Publication Number Publication Date
CN1309707A CN1309707A (zh) 2001-08-22
CN1322127C true CN1322127C (zh) 2007-06-20

Family

ID=10831992

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998086061A Expired - Fee Related CN1322127C (zh) 1998-05-13 1999-05-07 来自脑膜炎奈瑟氏球菌的basb029多核苷酸和多肽

Country Status (23)

Country Link
US (3) US6780419B1 (enExample)
EP (2) EP1621623A3 (enExample)
JP (2) JP4707832B2 (enExample)
KR (4) KR20100019461A (enExample)
CN (1) CN1322127C (enExample)
AT (1) ATE311457T1 (enExample)
AU (1) AU750032B2 (enExample)
BR (1) BR9910396A (enExample)
CA (1) CA2328403C (enExample)
CY (1) CY1105676T1 (enExample)
CZ (1) CZ299612B6 (enExample)
DE (1) DE69928658T2 (enExample)
DK (1) DK1078063T3 (enExample)
ES (1) ES2252946T3 (enExample)
GB (1) GB9810276D0 (enExample)
HU (1) HUP0102479A3 (enExample)
IL (2) IL139613A0 (enExample)
NO (2) NO326994B1 (enExample)
NZ (1) NZ508323A (enExample)
PL (1) PL197449B1 (enExample)
TR (1) TR200003347T2 (enExample)
WO (1) WO1999058683A2 (enExample)
ZA (1) ZA200006523B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
SG152917A1 (en) * 1998-01-14 2009-06-29 Chiron Srl Neisseria meningitidis antigens
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
ATE279943T1 (de) 1999-02-26 2004-11-15 Chiron Srl Verbesserung der bakterizidaktivität von neisseria antigenen mit cg enthaltende oligonukleotiden
GB9916529D0 (en) * 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
EP2275553B1 (en) 1999-10-29 2015-05-13 Novartis Vaccines and Diagnostics S.r.l. Neisserial antigenic peptides
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
CA2871789C (en) 2000-01-17 2017-04-04 Novartis Vaccines And Diagnostics S.R.L. Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
ES2389719T3 (es) * 2000-01-25 2012-10-30 The University Of Queensland Proteínas que comprenden regiones conservadas del antígeno de superficie de Neisseria meningitidis NhhA
JP4763210B2 (ja) 2000-02-28 2011-08-31 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル ナイセリアのタンパク質の異種発現
US20050232936A1 (en) 2001-07-27 2005-10-20 Chiron Corporation Meningococcus adhesins nada, app and orf 40
CA2489030A1 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
MXPA05003863A (es) 2002-10-11 2005-09-08 Chiron Srl Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos.
ES2397923T3 (es) 2003-10-02 2013-03-12 Novartis Ag Vacunas líquidas para múltiples serogrupos meningocócicos
US7459930B2 (en) * 2006-11-14 2008-12-02 Micron Technology, Inc. Digital calibration circuits, devices and systems including same, and methods of operation
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
GB0916570D0 (en) 2009-09-21 2009-10-28 Royal Holloway & Bedford New C Method
US9365624B2 (en) 2010-03-11 2016-06-14 Glaxosmithkline Biologicals, S.A. Vaccine
CA2859078A1 (en) * 2012-01-05 2013-07-11 Deutsches Krebsforschungszentrum Means and methods for treating or diagnosing idh1 r132h mutant-positive cancers
AU2016416450B2 (en) 2016-07-27 2021-08-12 Prysmian S.P.A. Flexible optical-fiber ribbon

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0301992A2 (en) * 1987-07-30 1989-02-01 Centro Nacional De Biopreparados Vaccine against group B Neisseria meningitidis, gammaglobulin and transfer factor
WO1993006861A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. VACCIN CONTRE LES INFECTIONS A $i(NEISSERIA MENINGITIDIS)
CN1284965A (zh) * 1997-12-12 2001-02-21 昆士兰大学 脑膜炎奈瑟氏球菌的新表面蛋白

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769240A (en) * 1980-09-15 1988-09-06 Bactex, Inc. Pili of neisseria and vaccine compositions containing same
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
US6245337B1 (en) * 1994-08-25 2001-06-12 Washington University Haemophilus adherence and penetration proteins
US6121037A (en) * 1994-10-18 2000-09-19 Stojiljkovic; Igor Bacterial hemoglobin receptor genes
US5646259A (en) * 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule
CU22559A1 (es) 1996-01-17 1999-05-03 Ct Ingenieria Genetica Biotech Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión
SG152917A1 (en) * 1998-01-14 2009-06-29 Chiron Srl Neisseria meningitidis antigens
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
NZ530640A (en) * 1999-04-30 2006-06-30 Chiron S Conserved neisserial antigens

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0301992A2 (en) * 1987-07-30 1989-02-01 Centro Nacional De Biopreparados Vaccine against group B Neisseria meningitidis, gammaglobulin and transfer factor
WO1993006861A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. VACCIN CONTRE LES INFECTIONS A $i(NEISSERIA MENINGITIDIS)
CN1284965A (zh) * 1997-12-12 2001-02-21 昆士兰大学 脑膜炎奈瑟氏球菌的新表面蛋白

Also Published As

Publication number Publication date
CA2328403C (en) 2013-11-05
WO1999058683A2 (en) 1999-11-18
KR20060076789A (ko) 2006-07-04
ATE311457T1 (de) 2005-12-15
BR9910396A (pt) 2001-10-30
WO1999058683A3 (en) 2000-04-06
AU4142099A (en) 1999-11-29
IL139613A0 (en) 2002-02-10
JP4707832B2 (ja) 2011-06-22
EP1078063A2 (en) 2001-02-28
EP1621623A3 (en) 2009-02-18
KR100673674B1 (ko) 2007-01-23
CY1105676T1 (el) 2010-12-22
NO326994B1 (no) 2009-03-30
PL345281A1 (en) 2001-12-03
TR200003347T2 (tr) 2001-06-21
ZA200006523B (en) 2001-11-12
DK1078063T3 (da) 2006-04-03
EP1078063B1 (en) 2005-11-30
IL139613A (en) 2014-03-31
DE69928658T2 (de) 2006-06-14
DE69928658D1 (de) 2006-01-05
KR20080070073A (ko) 2008-07-29
US6780419B1 (en) 2004-08-24
CN1309707A (zh) 2001-08-22
JP2002514424A (ja) 2002-05-21
WO1999058683A9 (en) 2002-05-02
CA2328403A1 (en) 1999-11-18
KR100897951B1 (ko) 2009-05-18
NO20090955L (no) 2001-01-11
HK1036300A1 (en) 2001-12-28
EP1621623A2 (en) 2006-02-01
HUP0102479A2 (hu) 2001-10-28
PL197449B1 (pl) 2008-03-31
US20090093622A1 (en) 2009-04-09
GB9810276D0 (en) 1998-07-15
NZ508323A (en) 2002-10-25
ES2252946T3 (es) 2006-05-16
CZ299612B6 (cs) 2008-09-17
NO20005696D0 (no) 2000-11-10
HUP0102479A3 (en) 2004-10-28
KR20100019461A (ko) 2010-02-18
US20040265332A1 (en) 2004-12-30
NO20005696L (no) 2001-01-11
KR20010043571A (ko) 2001-05-25
JP2010166921A (ja) 2010-08-05
AU750032B2 (en) 2002-07-11
CZ20004202A3 (en) 2001-05-16

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Granted publication date: 20070620

Termination date: 20160507