CN1316251A - 鼻窦炎康复胶囊 - Google Patents
鼻窦炎康复胶囊 Download PDFInfo
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Abstract
本发明为医药技术领域提供了一种鼻窦炎康复胶囊,其主要特点是根据中医扶正祛邪的基本治疗法则,采用麻黄、防风、羌活、辛夷、苍耳子、白芷、薄荷、菊花、柴胡、石膏、黄岑、猪胆浸膏、连翘、蒲公英、石菖蒲、茜草、细辛、藿香、苍术、川芎二十味药组成,与现有治疗鼻窦炎药物和方法相比,具有疗效显著、治疗费用低、无痛创等优点。
Description
本发明属于医药技术领域,是一种鼻窦炎康复胶囊
鼻窦炎为耳鼻喉常见病,该病在医学界被公认为难治之症。分急性和慢性两种,以慢性鼻窦炎较多见。本病过去认为多发于青少年和成人,现在认识到儿童发病亦不少见。鼻腔多种疾病均可引起鼻窦炎,且多以上呼吸道感染引起鼻窦炎为多见。常见致病菌为肺炎双球菌、链球菌、葡萄球菌、流感杆菌等。鼻腔粘膜有炎症时,窦腔粘膜也受累,窦口较细小,如发生狭窄或阻塞,鼻窦内的通风引流受到影响,导致窦内分泌物潴留易遭受感染。
该病在中医中谓之“鼻渊”(流浊涕,是脑受风热),“鼻鼽”(流清涕,是受风寒)。主要症状有鼻塞、头痛脑胀、嗅觉迟钝、鼻涕粘白或黄稠、有腥臭味,局部鼻岬肿胀肥犬等。严重者可引起眼部、耳部、呼吸道、消化道、颅面、颅内等多种并发症。因此治愈该病具有临床意义。
目前我国治疗鼻窦炎的方法有两种,一种是用药物治疗,一种是用手术治疗。1、药物治疗
目前我国常用的治疗鼻窦炎的内服药物有:鼻炎康、千柏鼻炎片、苍鹅鼻炎片,藿胆丸、鼻窦炎口服液等;常用的外用药物有:麻黄素滴鼻液、滴鼻净、鼻通、鼻眼净等,治愈疗效大都不佳。2、手术治疗
手术治疗有:上颌窦穿刺术、病灶部位注射药物或切口排脓术、或行鼻窦炎根治术。手术治疗给病人带来的痛苦不可言谕,而复发率很高。近年来,采取激光治疗鼻窦炎的效果,也未能取得患者的确信。
本发明的目的是提供一种对伤风感冒引起的鼻塞、头疼以及急、慢性鼻炎、鼻窦炎和过敏性鼻炎有良好的治疗效果,治疗费用低、无痛创的中药方。
鼻窦炎的发病机理主要是由于人体受外感风寒、风热等外界因素引起阴阳失调,导致肺气不能宣发卫气,影响肝脏的正常疏泄功能,则气血不能和调,升发不足,通达受阻。
根据中医扶正祛邪的基本治疗法则,认为该病是由风寒、湿热引起,治疗宜祛风化湿、清肝邪热,先祛邪而正自复。
该处方根据祖国医学理论,根据中医的治则治法,按照“君臣佐使”等组方原则,结合古今验方科学配伍,尽量满足中药复方中各单味药之间,在功效上存在上互促进、相互制约等复杂关系,使它们相得益彰,相辅相成,而治疗范围广、毒副作用小。从多年临床试验,不断调整复方中各药物的配伍,最后被实践证实,具有芳香通窍,祛风止痛,清浊化湿,解毒排脓等功效。
本药物的配方及配比关系(配比采用重量份)麻黄4.5-5.5、防风4.5-5.5、羌活4.5-5.5.辛夷4.5-5.5、苍耳子5.5-6.5、白芷5.5-6.5、薄荷2.5-3.5、菊花2.5-3.5、柴胡2.5-3.5、石膏1.5-2.5、黄岑4.5-5.5、猪胆浸膏1.5-2.5、连翘4.5-5.5、蒲公英4.5-5.5、石菖蒲4.5-5.5、茜草2.5-3.5、细辛2.5-3.5、藿香2.5-3.5、苍术4.5-5.5、川芎4.5-5.5二十味药组成。
以苍耳子祛风除湿通鼻窍,辛夷辛温走气而入肺,能助胃中清阳上行通于天,治头面鼻九窍之病,白芷芳香上达入手太阴肺经而消肿排脓生肌止痛。黄岑苦寒,能泻火补气而利肺达到消炎之作用。川芎上行头目,活血行气,祛风止痛。
配以辛温、辛寒解表药以发散表邪,增强宣肺散邪的作用;清热药主要作用在于清池里热,达到清热解毒消炎之功效;祛风湿药加强祛风除湿效力,达到舒筋,通络,止痛的作用;芳香化湿药辛香温燥,能疏畅气机;湿里药温肺化软,宣能鼻窍;化痰药开宣肺气,祛痰,排脓;解毒。
本方剂的君臣关系1、君药 辛夷
功效:表散风寒、温肺通窍。
本品辛温升散,体性轻浮,既能发散风寒表症,又散肺中风邪面升清阳以通鼻窍。是用于外感风寒鼻塞,治鼻渊的要药。
本品含有挥发油,有收缩鼻粘膜血管作用,可治疗各种鼻炎,尤其对过敏性鼻炎疗效更好。2、臣药 苍耳子 白芷
(1)苍耳子功效:散风祛,通鼻窍。
本品苦温燥湿,甘缓不峻,善于疏达宣散,取其通窍而治鼻渊、头痛。
本品含有苍耳子甙、生物碱、维生素C、脂肪、树脂等。
(2)白芷功效:祛风除湿、活血排脓。
本品辛温能通散活血,兼有芳香通窍的功效,可治鼻渊。
本品含有挥发油和白芷毒素,对大肠杆菌、结核杆菌、伤寒杆菌、副伤寒杆菌、绿脓杆菌、痢疾杆菌、霍乱弧菌及皮肤真菌均有抑制作用。
苍耳子、白芷,都具辛温升散,祛风除湿之功效,臣佐辛夷更能发挥其表散风寒,温肺通窍的作用,白芷有较好的活血排脓作用,相伍对治鼻渊效果更佳。3、佐使药 黄岑 猪胆浸膏 川芎
(1)黄岑功效:清热燥湿、泻火解毒。
本品苦寒,燥湿泄热,长于清肺热并能解毒。
本品含黄岑甙水解后,产生黄芩甙元和葡萄糖醛酸,黄芩甙元有利尿作用。黄岑酊剂对肠道有抑制作用,对痢疾杆菌、伤寒杆菌、绿脓杆菌、葡萄球菌、溶血性链球菌、肺炎双球菌、百日咳杆菌以及皮癣真菌、流感病毒,均有抑制作用。
(2)猪胆浸膏功效:清肺化痰、清热解毒。
本品清肺热,又祛痰止。配黄岑除肝胆湿热。
(3)川芎功效:活血气、祛风止痛。
本品辛温芳香、性善走散、上行头目、下达血海、既活血又行气,有“血中气药”之称。
本品含挥发油(内有一种内脂衍生物),挥发性油头生物碱、阿魏酸等。对大肠杆菌、痢疾杆菌、伤寒杆菌、绿脓杆菌、霍乱弧菌有抑制作用。
本方剂的剂型
1、口服胶囊
饮片粉碎后,过五号筛,混合均匀。药粉经紫外线照射三十分钟杀菌后,在无菌间装胶囊。装完胶囊后,再经紫外线灯照射三十分钟后,进行包装。
用OO号胶囊装药,每粒可装0.3克,每次服8粒,每次服量为2.4克。
2、水泛丸(也可做成)
饮片粉碎后,可制成每两300-500粒的小丸,每次服3克
3、浓缩丸(也可做成)
将饮片粉碎成粗粉后,用深溶浸提,经蒸发与干后可制成浓缩丸或片剂等。
鼻窦炎康复胶囊治疗周期:为十天一个疗程,严重的病人一般需四至六个疗程,较轻的病人一至二个疗程可痊愈。因感冒引起的鼻塞、流涕一般只需三天就会症状完全消失。
鼻窦炎康复胶囊一疗程药物的成本是14.70元左右,按六个疗程基本治愈一个慢性鼻窦炎病人,药物的成本才88.20元,治疗费用低是本药的又一大特点。
实施例1
麻黄5.5g、防风5.5g、羌活5.5g、辛夷5.5g、苍耳子5.5g、白芷6.5g、薄荷2.5g、菊花3.5g、柴胡2.5g、石膏1.5g、黄岑5.5g、猪胆浸膏1.5g、连翘5.5g、蒲公英4.5g、石菖蒲4.5g、茜草3.5g、细辛3.5g、藿香2.5g、苍术4.5g、川芎5.5g二十味药组成。实施例2
麻黄5g、防风5g、羌活5g、辛夷5g、苍耳子6g、白芷6g、薄荷3g、菊花3g、柴胡3g、石膏2g、黄岑5g、猪胆浸膏2g、连翘g、蒲公英5g、石菖蒲5g、茜草3g、细辛2g、藿香3g、苍术5g、川芎5g二十味药组成。典型病例:例1鲁某,女,17岁,南阳市燎河高三学生家住南阳市石油二机厂家属院。经本石医院诊断为鼻窦炎两年余、鼻塞、头痛、流脓涕等症状。曾服用过鼻炎康、鼻窦炎口服液等各在药物,疗效不明显。经老乡介绍本方,一疗程后症状全消失。例2高某,男,22岁,复员军人在二胶厂PS版车间工作,家住南阳市第二胶片厂第三家属区。有四、五年鼻窦炎发病史,穿刺过两次,在该市肿瘤医院窦部位注射药物治疗三次(该院承诺三针根治鼻窦炎),未消除任何症状。高某之父为中医大专毕业生,曾给其子服用过鼻炎康、千柏鼻炎片、苍鹅鼻炎片、藿胆丸等,疗效不明显。鼻塞、头痛、流脓涕、鼻岬肥大,有视力下降等症状。九九年正月初九,开始服用本药,七日后疗效明显,两个疗程后所有症状全部消失。例3曹某,男,44岁,新野县一高教师,患鼻炎有十多年病史,症状鼻塞、头痛、不闻香臭。经各方治疗都无济于事,服本方两个疗程的药(七天服了两个疗程的药),鼻塞、头痛的症头消失。一月后,开始有点能闻香臭。例4丁某,男,47岁,南阳市第二胶片厂职工,住该厂第三家属区。因感冒引起鼻塞、头痛、流清涕不止。服用本方三天后全部消失。丁某之子,10岁也因感冒引起鼻塞流清涕等症状,服本方三天后,症状全部消失。例5刘某,女,17岁,南阳理工学院学生,家住南阳市第二胶片厂第二家属区,被该市医院诊断为鼻窦为,曾做过两次穿刺术,有六、七年发病史,鼻岬肿大、鼻塞脓性分泌物、头昏、头痛、记忆减退等症状。服用本方两个疗程后脓性变清滋,鼻岬服大见小,又继续服两个疗程后,所有症状全部消失。例6沈某,男,32岁,第二胶片厂PS片钳工,家住第二胶片厂第一家属区。该患者在外治疗已花千余元未取得疗效,CT片显示为前组筛窦炎、鼻塞、清涕不断、头痛、记忆力减退等证状,服本方三日后,清涕明显减少,鼻塞减轻。二疗程后清涕基本没有,鼻塞现象有明显好转,服用四个疗程症状全部消失。
Claims (1)
1、一种鼻窦炎康复胶囊,其特征是由以下药物组成,配比采用重量份:麻黄4.5-5.5、防风4.5-5.5、羌活4.5-5.5、辛夷4.5-5.5、苍耳子5.5-6.5、白芷5.5-6.5、薄荷2.5-3.5、菊花2.5-3.5、柴胡2.5-3.5、石膏1.5-2.5、黄岑4.5-5.5、猪胆浸膏1.5-2.5、连翘4.5-5.5、蒲公英4.5-5.5、石菖蒲4.5-5.5、茜草2.5-3.5、细辛2.5-3.5、藿香2.5-3.5、苍术4.5-5.5、川芎4.5-5.5二十味药组成。
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WO2006007758A1 (fr) * | 2004-07-16 | 2006-01-26 | Zhiquan Zhao | Composition de medecine traditionnelle chinoise pour le traitement de la rhino-sinusite aigue et chronique |
CN100386105C (zh) * | 2005-03-11 | 2008-05-07 | 冀元成 | 治疗鼻炎的中药 |
CN101491621B (zh) * | 2009-03-12 | 2011-01-05 | 许建成 | 一种治疗鼻窦炎的中药组合物及其制备方法 |
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CN101972362A (zh) * | 2010-10-19 | 2011-02-16 | 吴子舟 | 一种治疗鼻窦炎的中药散剂及其配制方法 |
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