CN1313084A - Application of tea polyphenol in medicine to treat diseases in respiratory system - Google Patents

Application of tea polyphenol in medicine to treat diseases in respiratory system Download PDF

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Publication number
CN1313084A
CN1313084A CN 00112732 CN00112732A CN1313084A CN 1313084 A CN1313084 A CN 1313084A CN 00112732 CN00112732 CN 00112732 CN 00112732 A CN00112732 A CN 00112732A CN 1313084 A CN1313084 A CN 1313084A
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China
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tea polyphenols
medicine
application
respiratory system
preparation treatment
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CN 00112732
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CN1221253C (en
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陈建操
牛蓉
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Publication of CN1221253C publication Critical patent/CN1221253C/en
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Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A new application of tea polyphenol in medicine to treat diseases in respiratory system, especially the chronic bronchitis, bronchial asthma and pneumonectasis, is disclosed, which features high curative effect.

Description

The application of tea polyphenols in the medicine of treatment respiratory system disease
The present invention relates to the new medicine use of tea polyphenols, be specifically related to the application of tea polyphenols in the medicine of preparation treatment respiratory system disease, belong to the field of Chinese medicines.
Tea polyphenols is the polyphenols that extracts from Folium Camelliae sinensis, comprises catechin, flavonoid glycosides, and more than 30 kind of polyphenol component such as cyanine glycoside, phenolic acids etc. has stronger antioxygenic property.For the existing bibliographical information of the research of tea polyphenols.Multiple patent applications such as CN1142481A, CN1194966A, CN1186717A, CN1060488A, CN1071660A, CN1071844A, CN1056679A disclose the extracting method of tea polyphenols.The tea polyphenols that obtains with these methods can be used as food antioxidant, also can be used as medicinal.Medical value report for tea polyphenols may be summarized to be antitumor, blood fat reducing, blood sugar lowering, blood pressure lowering and cholesterol.But up to the present, the relevant tea polyphenols of Shang Weijian is used for the treatment of the report of respiratory system disease.
The present inventor is used for the treatment of respiratory system disease with regard to tea polyphenols and has carried out long research, thereby finished the present invention.
A kind of new pharmaceutical applications that the purpose of this invention is to provide tea polyphenols, i.e. the application of tea polyphenols in the medicine of preparation treatment respiratory system disease.
Respiratory system is made up of respiratory tract that transmits air and the lung that carries out gas exchange, and respiratory tract comprises parts such as nose, pharynx, larynx, trachea and bronchus.Because respiratory system communicates with the external world, be subjected to the direct effect of noxious stimulus in the external environment easily, and lung is again that the systemic blood circulating reflux must be through part, so that many factors can cause pulmonary disease, thereby respiratory system disease is more common internal disease.Respiratory system disease comprises rhinitis, pharyngitis, tonsillitis, chronic bronchitis, bronchiectasis, bronchial asthma, emphysema, pulmonary heart disease etc.Such sick sickness rate height, the course of disease is long, easily repeatedly, rhinitis, pharyngitis, tonsillitis patient's nasal obstruction, watery nasal discharge, pharyngeal drying, dull pain, tonsil redness, heating; Especially bronchitis, bronchiectasis, asthma, emphysema and patients with cor pulmonale when the affection of exogenous wind-cold acute attack, are coughed, expectorant, asthma shape increases the weight of, and dyspnea is agonizing.At present, such disease of western medical treatment, it often is symptomatic treatment, oral or instil some antiphlogistic antibacterial class medicine and hormoness, as ephedrine, aminophylline, epinephrine, isoproterenol, adrenocortical hormone etc., though can take effect temporary transient disease controlling at that time, but seldom can eradicate, and take the addiction that to bring such medicine for a long time.Though Chinese medicine has traditional decoction, adaptive surface is too wide, is difficult to timely disease controlling, also is difficult to remove old complaint.For the treatment of respiratory system disease,, still lack effective radical cure measure at present particularly for bronchitis, bronchial asthma, emphysema and pulmonary heart disease.Therefore, it is very important seeking a kind of natural drug that respiratory system disease is had a remarkable therapeutic effect, and tea polyphenols has been obtained excellent curative in this respect.
Tea polyphenols of the present invention has multiple extracting method, belongs to already known processes and mature technology, and existing commodity selling.
Tea polyphenols of the present invention is a kind of active constituents of medicine, preparation process according to routine, can be main active constituent with tea polyphenols, add excipient substances such as conventional excipient, flavoring agent, disintegrating agent, antiseptic, lubricant, wetting agent, binding agent, solvent, thickening agent, solubilizing agent, make any dosage form that is suitable for using clinically, as tablet, capsule, granule, oral liquid, injection, aerosol spray, drop, externally applied liniment etc.
Tea polyphenols of the present invention treatment rhinitis can be oral, also can take nasal cavity spray medicine, drip medicine or mode such as apply medicinal lotion or ointment.
Because the present invention discloses tea polyphenols treatment respiratory system disease first; particularly treat chronic bronchitis, bronchial asthma and emophysematous pharmacologic action; therefore; tea polyphenols is cooperated the making medicament separately or with other active constituent or adjuvant; so long as this medicament is used for the treatment of respiratory system disease; especially for treatment chronic bronchitis, bronchial asthma and emphysema, no matter for oral administration, external or injection all belong to protection scope of the present invention.
Tea polyphenols of the present invention all has the effect of treatment respiratory system disease when making any dosage form.Any medicament; if contain tea polyphenols in its component or only prepare patent medicine with the single composition of tea polyphenols; on signs such as its packing or description; and on other any propaganda materials; as long as indicate or point out and have the treatment respiratory system disease; treatment chronic bronchitis, bronchial asthma and emophysematous effect are particularly arranged, then fall within protection scope of the present invention.
Tea polyphenols of the present invention derives from the natural plants Folium Camelliae sinensis of medicine-food two-purpose, therefore, also tea polyphenols can be made health food or health care medicine.Health food or the health care medicine made with tea polyphenols; if on signs such as its packing or description, indicate or point out and have the treatment respiratory system disease; treatment chronic bronchitis, bronchial asthma and emophysematous effect are particularly arranged, also fall within protection scope of the present invention.
Embodiment 1
Prescription
Tea polyphenols 800 grams
Medical starch 200 grams
Above-mentioned component is gone into blender, stir, encapsulated with capsule machine, every filling 0.5 gram.Make 2000 of tea polyphenols capsules, every capsules contains 400 milligrams of tea polyphenols.
Embodiment 2
Tea polyphenols 250 grams
2000 milliliters of distilled water
Stevioside 1 gram
Tea polyphenols is dissolved in the distilled water fully mixing, adds stevioside, stirring and evenly mixing is once more packed in the vial with can filler, and every bottled 10 milligrams, sterilization makes the tea polyphenols oral liquid.
The medicine of Preparing Tea-polyphenol of the present invention is taken checking through routine patients up to a hundred, to rhinitis, pharyngitis, tonsillitis, chronic bronchitis, bronchiectasis, bronchial asthma, emphysema and pulmonary heart disease, all has good curative effect.According to age, body weight, condition of illness, patient takes 0.5-1.2 gram tea polyphenols at every turn, every day three times, after meal or take (rhinitis patient's nasal-cavity administration) one and a half hours ante cibum, positive effect is promptly arranged in one to three day.Rhinitis patient's nasal obstruction, watery nasal discharge transference cure; Pharyngitis patient's pharyngeal drying, dull pain, foreign body sensation disappear; Transference cures such as tonsillitis patient's tonsil redness, heating, pharyngalgia.Chronic bronchitis, bronchiectasis, bronchitis asthma, emphysema and the patients with cor pulmonale state of an illness are obviously controlled.After ten to 15 days, chronic bronchitis people's cough, expectoration, transference cure such as pant; Bronchiectasis patient's cough, a large amount of purulent sputum, transference cure such as spitting of blood or greatly alleviate repeatedly; Transference cure or most of disappearances such as the bronchospasm of asthma patient, dyspnea, pulmonary's wheezing sound; Transference cure such as uncomfortable in chest, out of breath, the dyspnea of emphysematic patients, edema of lower limbs, tachycardia, cyanosis or part disappear; Patients with cor pulmonale cough, expectoration, dyspnea, cyanosis, edema of lower limbs, the dried moist rale of pulmonary alleviate or reduce, the heart failure basic controlling.Take medicine after half a year to one year, light disease patient major part can be fully recovered, and the state of an illness of critically ill patient can significantly be taken a turn for the better.Take tea polyphenols treatment respiratory system disease of the present invention, total effective rate 99%, obvious effective rate is more than 95%.
The present invention has enlarged the range of application of tea polyphenols, has improved its exploitation and has been worth.With tea polyphenols treatment respiratory system disease of the present invention, special effect, remarkable, compound method is simple, does not see toxic and side effects after taking.

Claims (10)

1, the application of tea polyphenols in the medicine of preparation treatment respiratory system disease.
2, the application of tea polyphenols in the medicine of preparation treatment chronic bronchitis.
3, the application of tea polyphenols in the medicine of preparation treatment bronchiectasis.
4, the application of tea polyphenols in the medicine of preparation treatment bronchial asthma.
5, the application of tea polyphenols in the emophysematous medicine of preparation treatment.
6, the application of tea polyphenols in the medicine of preparation treatment pulmonary heart disease.
7, the application of tea polyphenols in the medicine of preparation treatment rhinitis.
8, the application of tea polyphenols in the medicine of preparation treatment pharyngitis.
9, the application of tea polyphenols in the tonsillitic medicine of preparation treatment.
10, the application of tea polyphenols in the health product of preparation treatment respiratory system disease.
CN 00112732 2000-03-09 2000-03-09 Application of tea polyphenol in medicine to treat diseases in respiratory system Expired - Fee Related CN1221253C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 00112732 CN1221253C (en) 2000-03-09 2000-03-09 Application of tea polyphenol in medicine to treat diseases in respiratory system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 00112732 CN1221253C (en) 2000-03-09 2000-03-09 Application of tea polyphenol in medicine to treat diseases in respiratory system

Publications (2)

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CN1313084A true CN1313084A (en) 2001-09-19
CN1221253C CN1221253C (en) 2005-10-05

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CN 00112732 Expired - Fee Related CN1221253C (en) 2000-03-09 2000-03-09 Application of tea polyphenol in medicine to treat diseases in respiratory system

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377563A (en) * 2016-11-17 2017-02-08 郑州郑先医药科技有限公司 Pharmaceutical composition for treating chronic pharyngitis
CN106421137A (en) * 2016-11-17 2017-02-22 郑州郑先医药科技有限公司 Compound preparation for treating chronic pharyngitis
CN106619645A (en) * 2016-11-17 2017-05-10 郑州郑先医药科技有限公司 Medicine for treating acute pharyngitis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377563A (en) * 2016-11-17 2017-02-08 郑州郑先医药科技有限公司 Pharmaceutical composition for treating chronic pharyngitis
CN106421137A (en) * 2016-11-17 2017-02-22 郑州郑先医药科技有限公司 Compound preparation for treating chronic pharyngitis
CN106619645A (en) * 2016-11-17 2017-05-10 郑州郑先医药科技有限公司 Medicine for treating acute pharyngitis

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