CN1192771C - Medicine for treating rheumatism and rheumatoid disease - Google Patents
Medicine for treating rheumatism and rheumatoid disease Download PDFInfo
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- CN1192771C CN1192771C CNB001129546A CN00112954A CN1192771C CN 1192771 C CN1192771 C CN 1192771C CN B001129546 A CNB001129546 A CN B001129546A CN 00112954 A CN00112954 A CN 00112954A CN 1192771 C CN1192771 C CN 1192771C
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- tea
- medicine
- rheumatic
- tea polyphenols
- pigment
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Abstract
The present invention discloses a new purpose of medicine of tea polyphenol and oxide thereof (tea pigment), namely a new purpose of the tea polyphenol and the oxide thereof (tea pigment) for preparing medicine and health care products to treat rheumatic and rheumatoid diseases, particularly a new purpose of the medicine of the tea polyphenol and the oxide thereof (tea pigment) for treating rheumatic heart diseases, rheumarthritis and rheumatoid arthritis. The tea polyphenol and the oxide thereof (tea pigment) are used for treating the rheumatic and rheumatoid diseases, and have conspicuous curative effect.
Description
Technical field
The present invention relates to the new medicine use of tea polyphenols and tea pigment thereof, be specifically related to the application that tea polyphenols and tea pigment thereof are used to prepare medicine or health product for treating rheumatism or rheumatoid disease, belong to natural medicine field.
Background technology
Tea polyphenols is the polyphenols that extracts from Folium Camelliae sinensis, comprises more than 30 kind of polyphenol components such as catechin, flavonoid glycosides, cyanine glycoside, phenolic acids, has stronger antioxygenic property.For the existing bibliographical information of the research of tea polyphenols.Multiple patent applications such as CN1142481A, CN1194966A, CN1186717A, CN1060488A, CN1071660A, CN1071844A, CN1056679A disclose the extracting method of tea polyphenols.The main body of tea polyphenols is a catechin, accounts for 70% to 80% of tea polyphenols substantially, and its oxidation product promptly is a tea pigment, comprises theaflavin, thearubigins and abrownin.The preparation method of tea pigment is tea polyphenols can be placed the air certain hour, autoxidation generation tea pigment; Also tea polyphenols heated oxide soluble in water can be generated tea pigment; Also can from Folium Camelliae sinensis, extract with patent application disclosed methods such as CN1081575A, CN1074459A, CN1074618A.With these methods with can be used as medicinal with tea polyphenols and oxide (tea pigment) thereof that additive method obtains.Medical value report for tea polyphenols and oxide (tea pigment) thereof may be summarized to be antitumor, blood fat reducing, blood sugar lowering, blood pressure lowering, cholesterol reducing, atherosclerosis, prevention and treatment cardiovascular disease.But up to the present, relevant tea polyphenols of Shang Weijian and tea pigment thereof are used for the treatment of the report of rheumatism or rheumatoid disease.
Summary of the invention
A kind of new medicinal usage that the purpose of this invention is to provide tea polyphenols and tea pigment thereof, be that tea polyphenols and tea pigment thereof are used to prepare medicine or health product for treating rheumatism or rheumatoid disease, particularly treat the new purposes of rheumatic heart disease, rheumatic arthritis or rheumatoid arthritis.
Rheumatism is a kind of chronic and systemic disease of acute attack repeatedly, often involves heart, joint, skin, blood vessel and brain, is subjected to harm maximum with heart again.Rheumatism can be damaged cardiac muscle, pericardium and the cardiac valve of heart, and the special damage cardiac valve forms rheumatic valvular heart disease, and severe patient can cause heart failure.Rheumatism comprises rheumatic heart disease, rheumatic arthritis, rheumatic arteritis, subcutaneous nodule and cutaneous annular erythema, especially with rheumatic heart disease and rheumatic arthritis to the physical impairment maximum, cure difficulty.Rheumatic heart disease mainly contains rheumatic carditis (rheumatic endocarditis, rheumatic myocarditis, rheumatic pericarditis), rheumatic valvular heart disease (mitral stenosis, mitral incompetence, aortic stenosis, aortic incompetence).Rheumatic arthritis is the arthropathy that is migration, mainly invades big joint such as shoulder, elbow, wrist, knee joint, hip, and is red during outbreak, swollen, bitterly, even stiff.Rheumatoid arthritis also is rheumatoid arthritis, and feature class is similar to rheumatic arthritis, divides maincenter type and peripheral.The maincenter type influences the post joint, and peripheral influences extremities joint.The peripheral pathological changes often is the multi-joint pathological changes, with hip, knee joint is more sees, is multiple and symmetry often, and ankylosis occurs, finally causes joint deformity.Maincenter type cardinal symptom is the lumbago and the difficulty of bending over, and can diffuse to lumbar vertebra, thoracic vertebra and cervical vertebra, and it is tetanic to cause post, can cause serious bow-backed deformity at last, even paralysis.
Western medical treatment rheumatism and rheumatoid disease are used aspirin, Phenylbutazone, naproxen, hormone and penicillin etc. always, but side effect are often arranged at present, also difficult thoroughly healing.Chinese traditional treatment, big at scope, slow curative effect is effected a radical cure also very difficult.Therefore, seek a kind of to rheumatism and rheumatoid disease, particularly the natural drug that rheumatic heart disease, rheumatic arthritis and rheumatoid arthritis are had a remarkable therapeutic effect is very important, and tea polyphenols and tea pigment thereof have excellent curative in this respect.
Tea polyphenols of the present invention and dark brownly have a multiple preparation method belongs to already known processes and mature technology, and existing commodity selling.
Tea polyphenols of the present invention and tea pigment thereof are a kind of active constituents of medicine, preparation process according to routine, can be main active constituent with tea polyphenols and/or tea pigment, add excipient substances such as conventional excipient, flavoring agent, disintegrating agent, antiseptic, lubricant, wetting agent, binding agent, solvent, thickening agent, solubilizing agent, make any tablet that is suitable for using clinically, capsule, granule, oral liquid or injection.
Tea polyphenols of the present invention and tea pigment thereof are made medicament, and the content of tea polyphenols and/or tea pigment can from 1% to 100% wait in the medicine, adopt 20% to 98% better.
Because the present invention discloses tea polyphenols and tea pigment treatment rheumatism or rheumatoid disease first; particularly treat the pharmacologic action of rheumatic heart disease, rheumatic arthritis or rheumatoid arthritis; therefore; tea polyphenols and/or tea pigment are made medicament; as long as this medicament is used for the treatment of rheumatism or rheumatoid disease; especially for treatment rheumatic heart disease, rheumatic arthritis or rheumatoid arthritis, all belong to protection scope of the present invention.
Tea polyphenols of the present invention and tea pigment thereof all have the effect of treatment rheumatism or rheumatoid disease when making any dosage form.Any medicament; if with tea polyphenols and/or tea pigment preparation; on signs such as its packing or description; and on other any propaganda materials; as long as indicate or point out and have treatment rheumatism or rheumatoid disease; the effect of treatment rheumatic heart disease, rheumatic arthritis or rheumatoid arthritis is particularly arranged, then fall within protection scope of the present invention.
Tea polyphenols of the present invention and tea pigment thereof derive from the natural plants Folium Camelliae sinensis of medicine-food two-purpose, therefore, tea polyphenols and/or tea pigment can be made health food or health care medicine.Health food or the health care medicine made with tea polyphenols and/or tea pigment; if on signs such as its packing or description, indicate or point out and have treatment rheumatism or rheumatoid disease; the effect of treatment rheumatic heart disease, rheumatic arthritis and rheumatoid arthritis is particularly arranged, also fall within protection scope of the present invention.
The medicine of tea polyphenols of the present invention and tea pigment preparation thereof is taken checking through 42 routine patients, to rheumatism or rheumatoid disease, particularly to rheumatic heart disease, rheumatic arthritis or rheumatoid arthritis, all has good curative effect.According to age, body weight, condition of illness, patient takes 0.5-1.2 gram tea polyphenols and/or tea pigment at every turn, every day three times, after meal or take one and a half hours ante cibum, promptly there was positive effect in two weeks, rheumatism and rheumatoid disease patient's symptom is alleviated, rheumatic heart patient's spitting of blood, out of breath, shirtfront pain, swift pulse and arrhythmia, heart failure etc. are alleviated or are controlled, the joint of rheumatic arthritis and rheumatoid arthritis patients is rubescent, swelling, pain, and symptoms such as movable difficulty are obviously alleviated.Take medicine after half a year to one year big recovery from illness of patient with slight symptoms or near recovery from illness, the various symptoms of patient with severe symptoms are clearly better.Take tea polyphenols of the present invention and tea pigment thereof treatment rheumatism and rheumatoid disease, particularly treat rheumatic heart disease, rheumatic arthritis and rheumatoid arthritis, total effective rate 98%, obvious effective rate is more than 94%.
The specific embodiment
Embodiment 1
Prescription
Tea polyphenols (or tea pigment) 800 grams
Medical starch 200 grams
Above-mentioned component is stirred, encapsulated, every filling 0.5 gram.Make 2000 of tea polyphenols (or tea pigment) capsules, every capsules contains 400 milligrams of tea polyphenols (or tea pigment).
Embodiment 2
Tea polyphenols 250 grams
2000 milliliters of distilled water
Stevioside 1 gram
Tea polyphenols is dissolved in stirring and evenly mixing in the distilled water, adds stevioside, stirring and evenly mixing is bottled once more, and every bottled 10 milligrams, sterilization makes the tea polyphenols oral liquid.
Embodiment 3
Prescription
Tea polyphenols 15 grams
White sugar 50 grams
Citric acid 5 grams
Carbonated water 930 grams
A small amount of Herba Menthae, vanilla
Various raw materials are mixed, stir, bottle, make the tea polyphenols beverage.
The present invention has enlarged the range of application of tea polyphenols and tea pigment thereof, has improved its exploitation and has been worth.With tea polyphenols of the present invention and tea pigment treatment rheumatism or rheumatoid disease, particularly treat rheumatic arthritis, rheumatoid arthritis and rheumatic heart disease, special effect, remarkable, compound method is simple, raw material is easy to get, and does not see toxic and side effects after taking.
Claims (7)
1, tea polyphenols and/or the tea pigment application in the medicine of preparation treatment rheumatism or rheumatoid disease.
2, application according to claim 1 is characterized in that medicine is tablet, capsule, granule, oral liquid or injection.
3, application according to claim 1 is characterized in that the content of tea polyphenols in the medicine and/or tea pigment is 20% to 98%.
4, application according to claim 1 is characterized in that described rheumatism is a rheumatic arthritis.
5, application according to claim 1 is characterized in that described rheumatoid disease is a rheumatoid arthritis.
6, application according to claim 1 is characterized in that described rheumatism is a rheumatic heart disease.
7, tea polyphenols and/or the tea pigment application in the health product of preparation treatment rheumatism or rheumatoid disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001129546A CN1192771C (en) | 2000-05-22 | 2000-05-22 | Medicine for treating rheumatism and rheumatoid disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001129546A CN1192771C (en) | 2000-05-22 | 2000-05-22 | Medicine for treating rheumatism and rheumatoid disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1324616A CN1324616A (en) | 2001-12-05 |
| CN1192771C true CN1192771C (en) | 2005-03-16 |
Family
ID=4582774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001129546A Expired - Fee Related CN1192771C (en) | 2000-05-22 | 2000-05-22 | Medicine for treating rheumatism and rheumatoid disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1192771C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106620315A (en) * | 2016-11-17 | 2017-05-10 | 郑州郑先医药科技有限公司 | Medicinal composition for treating rheumatism |
| CN106667990A (en) * | 2016-11-17 | 2017-05-17 | 郑州郑先医药科技有限公司 | Medicine for treating rheumatism |
| CN108144027A (en) * | 2018-01-04 | 2018-06-12 | 湖北瑞晟生物有限责任公司 | A kind of joint nursing oil and its preparation process |
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2000
- 2000-05-22 CN CNB001129546A patent/CN1192771C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1324616A (en) | 2001-12-05 |
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