CN1306825A - Adsorbed burn ointment - Google Patents
Adsorbed burn ointment Download PDFInfo
- Publication number
- CN1306825A CN1306825A CN 00102014 CN00102014A CN1306825A CN 1306825 A CN1306825 A CN 1306825A CN 00102014 CN00102014 CN 00102014 CN 00102014 A CN00102014 A CN 00102014A CN 1306825 A CN1306825 A CN 1306825A
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- activated carbon
- carbon powder
- wound
- regulator
- ooze
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Abstract
The adsorbed burn ointment consists of mainly active carbon powcer containing isoosmotic aid isotonic regulator and absorbent ointment matrix. It can eliminate effectively the wound toxic of burnt surface, reduce the damage of inflection to wound tissue and body and provide excellent condition for the cell multiplication in wound tissue, so it is used in repairing burnt wound.
Description
The invention belongs to a kind of burn cream, particularly a kind of blade coating is used to stick on various by the wound surface of burn and scald after making dressing on the gauze, to repair the adsorbed burn ointment of the wound surface of being burnt.
Repairing burn wound is to reach reparation burn wound this purpose by the basal cell of wound surface and wound surface border cell's division and proliferation, but a layer slough arranged in the burn wound, and there is wound fluid to ooze out, add suitable patient temperature, make burn wound constitute the good culture medium of antibacterial division growth.Can produce histotoxin after the burn slough decomposes, antibacterial can produce bacteriotoxin in the division growth process and during dead disintegrate, and histotoxin and bacteriotoxin are collectively referred to as the wound surface toxin.The wound surface toxin is very harmful to burn patient.It can disturb and delay the division and proliferation reparation of wound tissue cell on wound surface, even makes the wound tissue necrosis, in case their a large amount of penetrating in the burns human body also can cause the burn toxemia, causes multiple organ dysfunction syndrome, makes burn patient death.Therefore in the burn treating process, the harm of wound surface toxin should cause the attention that people are enough.We have had the many medicines that it can be killed to the noxious bacteria in the burn wound at present, but to the wound surface toxin, still do not have effective sweep-out method.
The object of the present invention is to provide a kind of adsorbed burn ointment, this burn cream can be removed the wound surface toxin while in the burn wound effectively, can also suppress the growth of various antibacterials on wound surface, and provide an excellent repairing environmental condition to burn wound.
The main component of adsorbed burn ointment provided by the present invention be contain etc. ooze, etc. open the activated carbon powder and the water absorption ointment substrate of regulator, wherein contain etc. ooze, etc. open the activated carbon powder of regulator percentage by weight be 10%～20%, the percentage by weight of water absorption ointment substrate is 80%-90%.
Containing etc. among the present invention ooze, etc. open regulator activated carbon powder in activated carbon powder, add etc. ooze, etc. open a regulator and make, ooze according to waiting, etc. open the difference that each kind of regulator can form the osmotic pressure ability, wait ooze, etc. open regulator weight be 0.5%～10% of activated carbon powder weight.Be used to make contain etc. ooze, etc. open the activated carbon powder that activated carbon powder adopted of regulator, measure by the method for inspection of Ministry of Forestry's ministry standard defined, its decolorizing ability to burnt sugar coloring should be not less than 100; And No. 3 medicines sieves that can all sieve by the serial medicine of the R40/3 of national standard.
In order to understand the present invention better, below with the invention will be further described.
Because activated carbon powder has very strong absorbability, its absorbability derives from a large amount of micropore that it has.The size of controlling its micropore just can be adsorbed the material that various material radiuses and its micropore radius adapt.Activated carbon powder has no side effect to wound tissue, can not absorbed by wound tissue, and the wound surface toxin belongs to hydrophilic larger molecular organics, with activated carbon powder very strong affinity is arranged, and is very easily adsorbed by activated carbon powder, so it is highly desirable to remove the wound surface toxin with it.Be placed in the wound fluid, it will adsorb the wound surface toxin that is present in the wound fluid automatically, and it can also adsorb the various antibacterials that are present in the wound fluid simultaneously.Reduce the quantity of various antibacterials on wound surface, thus the bacteriostasis of playing.Because activated carbon powder has a large amount of micropores, it is mixed the breathability that can also improve burn cream of the present invention in water absorption ointment substrate, the stifling sense of avoiding water absorption ointment substrate to bring to wound surface, too much wound fluid also can penetrate outside the dressing by the micropore of activated carbon powder on the wound surface simultaneously, thereby can play the effect of avoiding the wound surface dipping.Because activated carbon powder is to rely on wound fluid to do medium just can play this therapeutical effect of absorption wound surface toxin, when wound fluid more after a little while, activated carbon powder will can't adsorb the wound surface toxin because of lacking medium, thus in activated carbon powder, added wait ooze, etc. open regulator.Contain etc. ooze, etc. open regulator activated carbon powder in absorption wound surface toxin, its contained grade oozes, etc. open a regulator and also can dissolving slowly advance in the wound fluid.Dissolve in the wound fluid etc. ooze, etc. can form higher osmotic pressure after opening regulator.Under the effect of higher osmotic pressure, wound fluid can quicken to ooze out into the wound surface surface in the wound surface capillary network, to keep the balance of wound surface osmotic pressure.Wound surface toxin in wound tissue will be carried to the wound surface surface by wound fluid and be adsorbed like this.Because the molecular weight and the volume of absorption object (wound surface toxin) are bigger, therefore select for use the relatively advanced activated carbon powder of transitional pore (be that its pore radius is 20～1000 dusts, void content should be not less than 0.3 milliliter/gram) to make to contain wait ooze, etc. the activated carbon powder of a regulator.Also should control to some extent the activated carbon powder granularity simultaneously, crossing slightly can stimulate wound pain, crosses detailed rules and regulations and is difficult for exposing out from water absorption ointment substrate wound surface toxin and wound surface antibacterial are adsorbed.
In the present invention, water absorption ointment substrate is excipient, and it is to have added to have absorptive lipoidis substrate (as lanoline, Cera Flava etc.) or low quantity of surfactant (as spans surfactant etc.) and make among relatively poor hydrocarbon base of water absorption (as vaseline, paraffin wet goods) or oils substrate (as animal oil, plant wet goods).Water absorption ointment substrate can absorb the moisture of himself weight 10%～100% and be emulsified into water-in-oil type (W/O) emulsifiable paste matrix, and water absorption ointment substrate still can keep its semi-solid cream attitude and can be not mixed with water after suction emulsifying.With burn cream blade coating of the present invention after making dressing on the gauze, contain etc. ooze, etc. open regulator activated carbon powder will bury among water absorption ointment substrate.After dressing sticks in the burn wound, will absorb a small amount of wound fluid moisture content in the water absorption ointment substrate, and be emulsified into water-in-oil type (W/O) emulsifiable paste matrix.Because the skin wound tissue has very strong Absorption to emulsifiable paste matrix, the water absorption ointment substrate near wound tissue in the dressing can be absorbed by wound tissue.Bury like this containing etc. in water absorption ointment substrate ooze, etc. open regulator activated carbon powder just can part expose out and be immersed in the wound fluid, thereby can adsorb the wound surface toxin in wound fluid and in wound fluid, discharge wait ooze, etc. a regulator.Since contain wait ooze, etc. the particulate built on stilts effect of activated carbon powder of a regulator, water absorption ointment substrate near gauze in the dressing can not absorbed by wound tissue, thereby can continue to play ooze containing etc., etc. open the effect of activated carbon powder particle adhesion in dressing of regulator, make its unlikely coming off on wound surface.Treat that activated carbon powder absorption changes dressings after saturated, just the wound surface toxin can be excluded burn wound.In the present invention simultaneously, it can also play and cut off wound tissue and the extraneous effect that contact, and the evaporation that reduces moisture content to be preserving wound fluid, ooze for containing etc., etc. the activated carbon powder of a regulator adsorb the wound surface toxin medium basis be provided.Because water absorption ointment substrate also has lubrication, the adhesion that this can be avoided wound tissue and dressing, the pain when alleviating burn patient and changing dressings.
In sum, adsorbed burn ointment provided by the present invention can not only be removed the wound surface toxin effectively, and can also suppress the growth of various antibacterials in burn wound, and provides an excellent repairing environmental condition to wound surface.
Embodiment:
Make a kind of adsorbed burn ointment according to the present invention:
1, get the relatively advanced activated carbon powder of transitional pore and carry out screen analysis, choosing can be by No. 3 medicines sieve
Activated carbon powder is standby.By per 1000 gram activated carbon powders add 10 grams wait ooze, etc. open regulator
The ratio of sodium chloride takes by weighing sodium chloride and activated carbon powder respectively, adds an amount of water with sodium chloride
Join after the dissolving in the activated carbon powder of screen analysis and go and mix homogeneously, evaporating off water then
Divide just made contain wait ooze, etc. the activated carbon powder of a regulator.
2, the ratio that adds lanoline 100 grams in per 900 grams of vaseline takes by weighing vaseline and Pilus Caprae seu Ovis respectively
Fat heats both together and constantly to be stirred to condensation after dissolving, and has just made water absorption oil
Cream base matter.
3, by per 850 grams of water absorption ointment add contain etc. ooze, etc. open the activated carbon powder 150 of regulator
The ratio of gram take by weighing water absorption ointment substrate respectively and contain wait ooze, etc. the work of a regulator
The property powdered carbon, with water absorption ointment substrate heating dissolve the back add contain wait ooze, etc. open adjusting
The activated carbon powder of agent constantly is stirred to condensation, has promptly made absorption of the present invention and has burnt
Hinder cream.
Claims (3)
1, a kind of adsorbed burn ointment.It is characterized in that: the main component that constitutes this adsorbed burn ointment is to contain etc. to ooze.Deng the activated carbon powder and the water absorption ointment substrate of opening regulator, wherein contain wait ooze, etc. the percentage by weight of activated carbon powder of a regulator be 10%～20%, the percentage by weight of water absorption ointment substrate is 80%～90%.
2, adsorbed burn ointment according to claim 1, it is characterized in that containing etc. ooze, etc. open regulator activated carbon powder be in activated carbon powder, add etc. ooze, etc. open a regulator and make, ooze according to waiting, etc. open the difference of the osmotic pressure ability that each kind of regulator can form, wait ooze, etc. the weight of a regulator be 0.5%～10% of activated carbon powder weight.
3, adsorbed burn ointment according to claim 1 and 2.It is characterized in that the method for inspection mensuration of described activated carbon powder by Ministry of Forestry's ministry standard defined, its decolorizing ability to burnt sugar coloring is no less than 100.And can be all No. 3 medicines sieves of R40/3 series by national standard.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001020145A CN1137693C (en) | 2000-01-31 | 2000-01-31 | Adsorbed burn ointment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001020145A CN1137693C (en) | 2000-01-31 | 2000-01-31 | Adsorbed burn ointment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1306825A true CN1306825A (en) | 2001-08-08 |
| CN1137693C CN1137693C (en) | 2004-02-11 |
Family
ID=4576201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001020145A Expired - Fee Related CN1137693C (en) | 2000-01-31 | 2000-01-31 | Adsorbed burn ointment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1137693C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1982694A1 (en) | 2007-04-20 | 2008-10-22 | D.M.G. Italia Srl | Anti-oedema composition |
| CN105412203A (en) * | 2016-01-08 | 2016-03-23 | 赵先乾 | Composition for treating skin wound and preparation method thereof |
| CN105920039A (en) * | 2016-06-20 | 2016-09-07 | 李璐 | Application of nano activated carbon in preparation of skin wound repair medicine |
| CN105998064A (en) * | 2016-06-20 | 2016-10-12 | 李璐 | Application of nano activated carbon sol to preparation of medicine for treating eczema |
| DE102017010930A1 (en) | 2017-11-25 | 2019-05-29 | Dr. 3 Entwicklungsgesellschaft mbH i. Gr. | Topical preparations |
-
2000
- 2000-01-31 CN CNB001020145A patent/CN1137693C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1982694A1 (en) | 2007-04-20 | 2008-10-22 | D.M.G. Italia Srl | Anti-oedema composition |
| CN105412203A (en) * | 2016-01-08 | 2016-03-23 | 赵先乾 | Composition for treating skin wound and preparation method thereof |
| CN105920039A (en) * | 2016-06-20 | 2016-09-07 | 李璐 | Application of nano activated carbon in preparation of skin wound repair medicine |
| CN105998064A (en) * | 2016-06-20 | 2016-10-12 | 李璐 | Application of nano activated carbon sol to preparation of medicine for treating eczema |
| CN105920039B (en) * | 2016-06-20 | 2018-09-25 | 贵州泰柏妇科疾病研究中心 | A kind of application of active carbon nanoparticles in preparing skin wound repair medicine |
| CN105998064B (en) * | 2016-06-20 | 2019-01-22 | 贵州泰柏妇科疾病研究中心 | A kind of application of active carbon nanoparticles colloidal sol in the drug of preparation treatment eczema |
| DE102017010930A1 (en) | 2017-11-25 | 2019-05-29 | Dr. 3 Entwicklungsgesellschaft mbH i. Gr. | Topical preparations |
| WO2019101357A1 (en) | 2017-11-25 | 2019-05-31 | Dr. Deutz Kosmetik Gmbh | Topical preparations |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1137693C (en) | 2004-02-11 |
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