CN1306040C - 高血压的定量诊断分析 - Google Patents

高血压的定量诊断分析 Download PDF

Info

Publication number
CN1306040C
CN1306040C CNB028086481A CN02808648A CN1306040C CN 1306040 C CN1306040 C CN 1306040C CN B028086481 A CNB028086481 A CN B028086481A CN 02808648 A CN02808648 A CN 02808648A CN 1306040 C CN1306040 C CN 1306040C
Authority
CN
China
Prior art keywords
snp
leu
hypertension
hsgk1
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028086481A
Other languages
English (en)
Chinese (zh)
Other versions
CN1503848A (zh
Inventor
弗洛里安·朗
A·布斯耶恩
F·C·卢夫特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN1503848A publication Critical patent/CN1503848A/zh
Application granted granted Critical
Publication of CN1306040C publication Critical patent/CN1306040C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/723Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CNB028086481A 2001-03-21 2002-03-21 高血压的定量诊断分析 Expired - Fee Related CN1306040C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10113876.8 2001-03-21
DE10113876A DE10113876A1 (de) 2001-03-21 2001-03-21 Quantitative diagnostische Analyse der Hypertonie

Publications (2)

Publication Number Publication Date
CN1503848A CN1503848A (zh) 2004-06-09
CN1306040C true CN1306040C (zh) 2007-03-21

Family

ID=7678460

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028086481A Expired - Fee Related CN1306040C (zh) 2001-03-21 2002-03-21 高血压的定量诊断分析

Country Status (17)

Country Link
US (1) US20060127892A1 (enExample)
EP (1) EP1390531B1 (enExample)
JP (1) JP2004528032A (enExample)
CN (1) CN1306040C (enExample)
AT (1) ATE331043T1 (enExample)
AU (1) AU2002244751B2 (enExample)
CA (1) CA2441314C (enExample)
CY (1) CY1105566T1 (enExample)
DE (2) DE10113876A1 (enExample)
DK (1) DK1390531T3 (enExample)
ES (1) ES2266463T3 (enExample)
HU (1) HUP0303491A3 (enExample)
MX (1) MXPA03008522A (enExample)
PL (1) PL364387A1 (enExample)
PT (1) PT1390531E (enExample)
RU (1) RU2287160C2 (enExample)
WO (1) WO2002074987A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003053363A2 (en) * 2001-12-19 2003-07-03 Millennium Pharmaceuticals, Inc. Human diacylglycerol acyltransferase 2 (dgat2) family members and uses therefor
US6830911B2 (en) * 2002-02-08 2004-12-14 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
DE10305213A1 (de) * 2003-02-07 2004-08-26 Florian Prof. Dr.med. Lang Verwendung eines neuen Polymorphismus im hsgk1-Gen zur Diagnose der Hypertonie und Verwendung der sgk-Genfamilie zur Diagnose und Therapie des Long-Q/T-Syndroms
JP4762552B2 (ja) * 2003-03-03 2011-08-31 フロリアン ラング、 診断用および治療用標的としてのsgk1
DE10346913A1 (de) 2003-10-09 2005-05-04 Merck Patent Gmbh Acylhydrazonderivate
RU2261442C2 (ru) * 2003-12-09 2005-09-27 Государственное образовательное учреждение высшего профессионального образования "Нижегородская Государственная Медицинская академия" МЗ РФ (ГОУ ВПО НижГМА) Способ диагностики артериальной гипертензии
WO2007025792A1 (de) * 2005-09-02 2007-03-08 Florian Lang Verfahren zur diagnose von hypertonie
CN102654893A (zh) * 2011-03-04 2012-09-05 苏州卫生职业技术学院 分析高尿酸血症和高血压患病率关系的方法
WO2023114714A1 (en) * 2021-12-14 2023-06-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Sgk1 inhibitory compositions and methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000062781A1 (de) * 1999-04-20 2000-10-26 Florian Lang Arzneimittel enthaltend hemmstoffe der zellvolumenregulierten humanen kinase h-sgk

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000062781A1 (de) * 1999-04-20 2000-10-26 Florian Lang Arzneimittel enthaltend hemmstoffe der zellvolumenregulierten humanen kinase h-sgk

Also Published As

Publication number Publication date
HK1063338A1 (en) 2004-12-24
RU2003130071A (ru) 2005-04-10
CY1105566T1 (el) 2010-07-28
HUP0303491A3 (en) 2005-12-28
WO2002074987A3 (de) 2003-12-04
DK1390531T3 (da) 2006-10-23
RU2287160C2 (ru) 2006-11-10
EP1390531A2 (de) 2004-02-25
MXPA03008522A (es) 2005-03-07
CA2441314C (en) 2011-11-08
JP2004528032A (ja) 2004-09-16
AU2002244751C1 (en) 2002-10-03
US20060127892A1 (en) 2006-06-15
ATE331043T1 (de) 2006-07-15
CN1503848A (zh) 2004-06-09
PL364387A1 (en) 2004-12-13
ES2266463T3 (es) 2007-03-01
HUP0303491A2 (hu) 2004-08-30
CA2441314A1 (en) 2002-09-26
DE10113876A1 (de) 2002-09-26
EP1390531B1 (de) 2006-06-21
PT1390531E (pt) 2006-09-29
WO2002074987A2 (de) 2002-09-26
AU2002244751B2 (en) 2007-01-11
DE50207305D1 (de) 2006-08-03

Similar Documents

Publication Publication Date Title
Yin et al. Genetic variations of CYP2C9 in 724 Japanese individuals and their impact on the antihypertensive effects of losartan
CA2701202C (en) Biomarkers for autism spectrum disorders
CN1251616A (zh) 大规模鉴定疾病基因型的方法和6型脊髓小脑共济失调的诊断试验
CN1547613A (zh) 评估施用自身或者其代谢中间物被ugt1a1酶代谢的化合物引起严重毒性的方法
CN1306040C (zh) 高血压的定量诊断分析
Pan et al. Angiotensin-converting enzyme gene 2350 G/A polymorphism is associated with left ventricular hypertrophy but not essential hypertension
CN1761760A (zh) hsgk1基因中新的多态性在诊断高血压中的用途和sgk基因家族在诊断和治疗长Q/T综合征中的用途
HK1063338B (zh) 高血压的定量诊断分析
CN1749415A (zh) 硝酸甘油治疗急性心绞痛疗效检测方法和试剂盒
CN1724692A (zh) 一种检测白血病易感性的试剂盒和方法
CN1730655A (zh) 与人类遗传性耳聋相关的gjb6突变基因及其在诊断遗传性耳聋中的应用
CN1891822A (zh) 具有特定单核苷酸多态性的th基因及其检测方法和用途
CN1882604A (zh) 肥胖症的遗传标记
CN101033487A (zh) 检测与原发性高血压相关的KLK1基因rs5517多态的方法
CN1495191A (zh) 具有新的单核苷酸多态性的HNF-1α基因变体和其编码的蛋白质变体
HK1089792A (en) Use of a novel polymorphism in the hsgk1 gene in the diagnosis of hypertonia and use of the sgk gene family in the diagnosis and therapy of the long qt syndrome
CN1661063A (zh) 触珠蛋白基因与原发性高血压的相关性
CN1661058A (zh) 触珠蛋白基因与原发性高血压的相关性
CN1661062A (zh) 触珠蛋白基因与原发性高血压的相关性
CN1661056A (zh) 触珠蛋白基因与原发性高血压的相关性
CN1690222A (zh) 耳聋相关基因突变的检测方法
CN1515686A (zh) 用于预测糖尿病易感性的试剂盒及所用引物
CN1696154A (zh) 乳腺癌相关蛋白、编码该蛋白的基因和诊断乳腺癌的方法
CN1661072A (zh) 精氨酸升压素受体1a基因与原发性高血压的相关性
CN1705754A (zh) P2y12受体的h2单元型与增加的血栓形成和外周动脉疾病的危险相关

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1063338

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20070321

Termination date: 20130321